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Sospeter Njeru

Kenya
LGSA Associate

ORP3 is a Tumour Suppressor Protein in the B-Cell Lineage of Aging Mice

Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Rudolph Research Group

First Supervisor:

Karl Lenhard Rudolph (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Co – Supervisor(s):

Stephan Diekmann (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Doctoral Disputation:

2019

Publications 2020:

  • Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor.
    Njeru* SN, Kraus* J, Meena* JK, Lechel A, Katz SF, Kumar M, Knippschild U, Azoitei A, Wezel F, Bolenz C, Leithäuser F, Gollowitzer A, Omrani O, Hoischen C, Koeberle A, Kestler** HA, Günes** C, Rudolph** KL
    Oncogene 2020, 39(7), 1445-65 * equal contribution, ** co-corresponding authors

    • Publications 2019:

    • Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.
      Chen Z, Amro EM, Becker F, Hölzer M, Rasa SMM, Njeru SN, Han B, Di Sanzo S, Chen Y, Tang D, Tao S, Haenold R, Groth M, Romanov VS, Kirkpatrick JM, Kraus JM, Kestler HA, Marz M, Ori A, Neri F, Morita** Y, Rudolph** KL
      J Exp Med 2019, 216(1), 152-75 ** co-corresponding authors
    • ORP3 is a tumor suppressor protein in the B-cell lineage of aging mice
      Njeru SN
      Dissertation 2019, Jena, Germany

    Publications 2017:

    • Prospects for malaria control through manipulation of mosquito larval habitats and olfactory-mediated behavioural responses using plant-derived compounds.
      Muema JM, Bargul JL, Njeru SN, Onyango JO, Imbahale SS
      Parasit Vectors 2017, 10(1), 184