Friedrich Becker

Germany
LGSA Member

Vitamin A metabolism in niche cells activates retinoic acid signaling and impairs stem cell function and skeletal muscle maintenance in aging mice

Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Rudolph Research Group

First Supervisor:

Karl Lenhard Rudolph (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Doctoral Disputation:

2021

Publications 2022:

  • Vitamin A metabolism in niche cells activates retinoic acid signaling and impairs stem cell function and skeletal muscle maintenance in aging mice
    Becker F
    Dissertation 2022, Jena
  • pH-sensitive packaging of cationic particles by an anionic block copolymer shell.
    Solomun JI, Martin L, Mapfumo P, Moek E, Amro E, Becker F, Tuempel S, Hoeppener S, Rudolph KL, Traeger A
    J Nanobiotechnology 2022, 20(1), 336

Publications 2021:

  • Targeting enzyme aging.
    Becker F, Rudolph KL
    Science 2021, 371(6528), 462-3

Publications 2020:

  • Elevated Hedgehog activity contributes to attenuated DNA damage responses in aged hematopoietic cells.
    Scheffold A, Baig AH, Chen Z, von Löhneysen SE, Becker F, Morita Y, Avila AI, Groth M, Lechel A, Schmid F, Kraus JM, Kestler HA, Stilgenbauer S, Philipp M, Burkhalter MD
    Leukemia 2020, 34(4), 1125-34

Publications 2019:

  • Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.
    Chen Z, Amro EM, Becker F, Hölzer M, Rasa SMM, Njeru SN, Han B, Di Sanzo S, Chen Y, Tang D, Tao S, Haenold R, Groth M, Romanov VS, Kirkpatrick JM, Kraus JM, Kestler HA, Marz M, Ori A, Neri F, Morita** Y, Rudolph** KL
    J Exp Med 2019, 216(1), 152-75 ** co-corresponding authors
  • Author Correction: Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.
    Schwörer S, Becker F, Feller C, Baig AH, Köber U, Henze H, Kraus JM, Xin B, Lechel A, Lipka DB, Varghese CS, Schmidt M, Rohs R, Aebersold R, Medina KL, Kestler HA, Neri F, von Maltzahn** J, Tümpel** S, Rudolph** KL
    Nature 2019, 572(7769), E11-5 ** co-corresponding authors