Marco Groth

Germany
LGSA Member

Funktionelle Genomik von Defensinen bei Prostatakarzinom - hochauflösende Kopienzahlbestimmung und Hochdurchsatz-Genotypisierung des Gen-Clusters auf 8p23.1

Leipzig University Medical Center
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Platzer Research Group

First Supervisor:

Klaus Huse (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Co – Supervisor(s):

Gerd Birkenmeier (University of Leipzig)

Doctoral Disputation:

2009

Publications 2010:

  • A label-free assay of exonuclease activity using a pyrosequencing technique.
    Gührs KH, Groth M, Grosse F
    Anal Biochem 2010, 405(1), 11-8
  • Publications 2009:

    • Comparison of multiplex ligation-dependent probe amplification and real-time PCR accuracy for gene copy number quantification using the beta-defensin locus.
      Perne A, Zhang X, Lehmann L, Groth M, Stuber F, Book M
      Biotechniques 2009, 47(6), 1023-8
    • DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution.
      Zhang Y, Rohde C, Tierling S, Jurkowski TP, Bock C, Santacruz D, Ragozin S, Reinhardt R, Groth M, Walter J, Jeltsch A
      PLoS Genet 2009, 5(3), e1000438

    Publications 2008:

    • High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes.
      Groth* M, Szafranski* K, Taudien S, Huse K, Mueller O, Rosenstiel P, Nygren AOH, Schreiber S, Birkenmeier G, Platzer M
      Hum Mutat 2008, 29(10), 1247-54 * equal contribution
    • Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors.
      Hollenbach M, Hintersdorf A, Huse K, Sack U, Bigl M, Groth M, Santel T, Buchold M, Lindner I, Otto A, Sicker D, Schellenberger W, Almendinger J, Pustowoit B, Birkemeyer C, Platzer M, Oerlecke I, Hemdan N, Birkenmeier G
      Biochem Pharmacol 2008, 76(5), 631-44
    • Genetic variants of the copy number polymorphic beta-defensin locus are associated with sporadic prostate cancer.
      Huse K, Taudien S, Groth M, Rosenstiel P, Szafranski K, Hiller M, Hampe J, Junker K, Schubert J, Schreiber S, Birkenmeier G, Krawczak M, Platzer M
      Tumour Biol 2008, 29(2), 83-92
    • Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity.
      Santel T, Pflug G, Hemdan NYA, Schäfer A, Hollenbach M, Buchold M, Hintersdorf A, Lindner I, Otto A, Bigl M, Oerlecke I, Hutschenreuter A, Sack U, Huse K, Groth M, Birkemeyer C, Schellenberger W, Gebhardt R, Platzer M, Weiss T, Vijayalakshmi MA, Krüger M, Birkenmeier G
      PLoS One 2008, 3(10), e3508

    Publications 2006:

    • Method for preparing single-stranded DNA templates for Pyrosequencing using vector ligation and universal biotinylated primers.
      Groth* M, Huse* K, Reichwald K, Taudien S, Hampe J, Rosenstiel P, Birkenmeier G, Schreiber S, Platzer M
      Anal Biochem 2006, 356(2), 194-201 * equal contribution