Manuel Schmidt

Publications 2022:

• The hairpin region of WNT7A is sufficient for binding to the Frizzled7 receptor and to elicit signaling in myogenic cells
  Schmidt M, Poser C, Janster C, von Maltzahn J
  Comput Struct Biotechnol J 2022, 20
  

Publications 2021:

• Stimulation of Non-canonical NF-κB Through Lymphotoxin-β-Receptor Impairs Myogenic Differentiation and Regeneration of Skeletal Muscle.
  Schmidt M, Weidemann A, Poser C, Bigot A, von Maltzahn J
  Front Cell Dev Biol 2021, 9, 721543
  

Publications 2020:

• Wnt7a Counteracts Cancer Cachexia.
  Schmidt M, Poser C, von Maltzahn J
  Mol Ther Oncolytics 2020, 16, 134-46
  

Publications 2019:

• Analyzing Satellite Cell Function During Skeletal Muscle Regeneration by Cardiotoxin Injury and Injection of Self-delivering siRNA In Vivo.
  Ahrens* HE, Henze* H, Schüler SC, Schmidt M, Hüttner SS, von Maltzahn J
  J Vis Exp 2019, e60194 * equal contribution
  
• Isolation and Culture of Individual Myofibers and Their Adjacent Muscle Stem Cells from Aged and Adult Skeletal Muscle.
  Hüttner SS, Ahrens HE, Schmidt M, Henze H, Jung MJ, Schüler SC, von Maltzahn J
  Methods Mol Biol 2019, 2045, 25-36
  
• Author Correction: Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.
  Schwörer S, Becker F, Feller C, Baig AH, Köber U, Henze H, Kraus JM, Xin B, Lechel A, Lipka DB, Varghese CS, Schmidt M, Rohs R, Aebersold R, Medina KL, Kestler HA, Neri F, von Maltzahn** J, Tümpel** S, Rudolph** KL
  Nature 2019, 572(7769), E11-5 ** co-corresponding authors
  

Publications 2018:

• Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle.
  Ahrens* HE, Huettemeister* J, Schmidt M, Kaether C, von Maltzahn J
  Skelet Muscle 2018, 8(1), 20 * equal contribution
  
• Thyroid Hormone Transporters MCT8 and OATP1C1 Control Skeletal Muscle Regeneration.
  Mayerl S, Schmidt M, Doycheva D, Darras VM, Hüttner SS, Boelen A, Visser TJ, Kaether C, Heuer** H, von Maltzahn** J
  Stem Cell Reports 2018, 10(6), 1959-74 ** co-corresponding authors
  
• Towards prevention of loss of muscle stem cell function during aging and prevention of cancer cachexia.
  Schmidt M
  Dissertation 2018, Jena, Germany
  

Publications 2016:

• Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice.
  Lukjanenko L, Jung MJ, Hegde N, Perruisseau-Carrier C, Migliavacca E, Rozo M, Karaz S, Jacot G, Schmidt M, Li L, Metairon S, Raymond F, Lee U, Sizzano F, Wilson DH, Dumont NA, Palini A, Fässler R, Steiner P, Descombes P, Rudnicki MA, Fan CM, von Maltzahn J, Feige JN, Bentzinger CF
  Nat Med 2016, 22(8), 897-905
  
• Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.
  Schwörer S, Becker F, Feller C, Baig AH, Köber U, Henze H, Kraus JM, Xin B, Lechel A, Lipka DB, Varghese CS, Schmidt M, Rohs R, Aebersold R, Medina KL, Kestler HA, Neri F, von Maltzahn** J, Tümpel** S, Rudolph** KL
  Nature 2016, 540(7633), 428-32 ** co-corresponding authors