Marco Groth
Germany
LGSA Member
Funktionelle Genomik von Defensinen bei Prostatakarzinom - hochauflösende Kopienzahlbestimmung und Hochdurchsatz-Genotypisierung des Gen-Clusters auf 8p23.1
Leipzig University Medical Center
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Platzer Research Group
First Supervisor:
Klaus Huse (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))Co – Supervisor(s):
Gerd Birkenmeier (University of Leipzig)Doctoral Disputation:
2009Publications 2010:
- A label-free assay of exonuclease activity using a pyrosequencing technique.
Gührs KH, Groth M, Grosse F
Anal Biochem 2010, 405(1), 11-8 - Comparison of multiplex ligation-dependent probe amplification and real-time PCR accuracy for gene copy number quantification using the beta-defensin locus.
Perne A, Zhang X, Lehmann L, Groth M, Stuber F, Book M
Biotechniques 2009, 47(6), 1023-8 - DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution.
Zhang Y, Rohde C, Tierling S, Jurkowski TP, Bock C, Santacruz D, Ragozin S, Reinhardt R, Groth M, Walter J, Jeltsch A
PLoS Genet 2009, 5(3), e1000438 - High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes.
Groth* M, Szafranski* K, Taudien S, Huse K, Mueller O, Rosenstiel P, Nygren AOH, Schreiber S, Birkenmeier G, Platzer M
Hum Mutat 2008, 29(10), 1247-54 * equal contribution - Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors.
Hollenbach M, Hintersdorf A, Huse K, Sack U, Bigl M, Groth M, Santel T, Buchold M, Lindner I, Otto A, Sicker D, Schellenberger W, Almendinger J, Pustowoit B, Birkemeyer C, Platzer M, Oerlecke I, Hemdan N, Birkenmeier G
Biochem Pharmacol 2008, 76(5), 631-44 - Genetic variants of the copy number polymorphic beta-defensin locus are associated with sporadic prostate cancer.
Huse K, Taudien S, Groth M, Rosenstiel P, Szafranski K, Hiller M, Hampe J, Junker K, Schubert J, Schreiber S, Birkenmeier G, Krawczak M, Platzer M
Tumour Biol 2008, 29(2), 83-92 - Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity.
Santel T, Pflug G, Hemdan NYA, Schäfer A, Hollenbach M, Buchold M, Hintersdorf A, Lindner I, Otto A, Bigl M, Oerlecke I, Hutschenreuter A, Sack U, Huse K, Groth M, Birkemeyer C, Schellenberger W, Gebhardt R, Platzer M, Weiss T, Vijayalakshmi MA, Krüger M, Birkenmeier G
PLoS One 2008, 3(10), e3508