Home>People>Graduates

Jing Lu

China
LGSA Member

Interaction between epithelial cells and immune cells in the intestine during aging

Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Neri Research Group

First Supervisor:

Francesco Neri (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Co – Supervisor(s):

Steve Hoffmann (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Doctoral Disputation:

2023

Publications 2024:

  • Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis
    Minetti A, Omrani O, Brenner C, Allies G, Imada S, Rösler J, Khawaled S, Cansiz F, W.Meckelmann S, Gebert N, Heinze I, Lu J, Spengler K, Rasa M, Heller R, Yilmaz O, Tasdogan A, Neri F, Ori A
    bioRxiv 2024, https://doi.org/10.1101/2024.07.

    • Publications 2023:

    • Interaction between epithelial cells and immune cells in the intestine during aging
      Lu J
      Dissertation 2023, Jena, Germany
    • Author Correction: IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration.
      Omrani* O, Krepelova* A, Rasa SMM, Sirvinskas D, Lu J, Annunziata F, Garside G, Bajwa S, Reinhardt S, Adam L, Käppel S, Ducano N, Donna D, Ori A, Oliviero S, Rudolph KL, Neri F
      Nat Commun 2023, 14(1), 6302 * equal contribution
    • IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration.
      Omrani* O, Krepelova* A, Rasa SMM, Sirvinskas D, Lu J, Annunziata F, Garside G, Bajwa S, Reinhardt S, Adam L, Käppel S, Ducano N, Donna D, Ori A, Oliviero S, Rudolph KL, Neri F
      Nat Commun 2023, 14(1), 6109 * equal contribution

    Publications 2022:

    • Paneth cells drive intestinal stem cell competition and clonality in aging and calorie restriction
      Annunziata F, Rasa SMM, Krepelova A, Lu J, Minetti A, Omrani O, Nunna S, Adam L, Käppel S, Neri F
      Eur J Cell Biol 2022, 101(4), 151282
    • Establishment and evaluation of module-based immune-associated gene signature to predict overall survival in patients of colon adenocarcinoma.
      Lu J, Annunziata F, Sirvinskas D, Omrani O, Li H, Rasa SMM, Krepelova A, Adam L, Neri F
      J Biomed Sci 2022, 29(1), 81
    • Androgen-Induced MIG6 Regulates Phosphorylation of Retinoblastoma Protein and AKT to Counteract Non-Genomic AR Signaling in Prostate Cancer Cells.
      Schomann T, Mirzakhani K, Kallenbach J, Lu J, Rasa SMM, Neri F, Baniahmad A
      Biomolecules 2022, 12(8), 1048
    • Single-cell atlas of the aging mouse colon.
      Širvinskas D, Omrani O, Lu J, Rasa M, Krepelova A, Adam L, Kaeppel S, Sommer F, Neri F
      iScience 2022, 25(5), 104202

    Publications 2021:

    • Characterization of an in vitro 3D intestinal organoid model by using massive RNAseq-based transcriptome profiling.
      Lu J, Krepelova A, Rasa SMM, Annunziata F, Husak O, Adam L, Nunna S, Neri F
      Sci Rep 2021, 11(1), 16668