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Maja Dziegelewska

Poland
LGSA Member

Characterization of naked mole-rat cystathionine beta synthase

Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Platzer Research Group

First Supervisor:

Matthias Platzer (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Doctoral Disputation:

2018

Publications 2018:

  • The high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) may explain naked mole-rat's distinct methionine metabolite profile compared to mouse.
    Olecka M, Huse K, Platzer M
    Geroscience 2018, 40(4), 359-60
  • Exploring the basis of naked mole-rat healthspan by characterization of its transsulfuration pathway and hydroxymethylome.
    Olecka MK
    Dissertation 2018, Jena, Germany

Publications 2016:

  • Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat.
    Dziegelewska M, Holtze S, Vole C, Wachter U, Menzel U, Morhart M, Groth M, Szafranski K, Sahm A, Sponholz C, Dammann P, Huse K, Hildebrandt** T, Platzer** M
    Redox Biol 2016, 8, 192-8 ** co-senior authors