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Amit Kumar

India
LGSA Member

Structural investigations on heme-interacting proteins

Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): CS Protein Production - Project Ohlenschlaeger

First Supervisor:

Oliver Ohlenschläger (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Co – Supervisor(s):

Stefan H. Heinemann (Friedrich Schiller University Jena (FSU))

Doctoral Disputation:

2019

Publications 2022:

  • NMR of intrinsically disordered proteins: A note on the application of 15 N-13 Cα het-TOCSY mixing for 13 Cα magnetisation transfers.
    Kumar A, Wiedemann C, Bellstedt P, Ramachandran R, Ohlenschläger O
    J Magn Reson 2022, 337, 107166

    • Publications 2020:

    • 1 H, 13 C, and 15 N Backbone assignments of the human brain and acute leukemia cytoplasmic (BAALC) protein.
      Lang A, Kumar A, Jirschitzka J, Bordusa F, Ohlenschläger O, Wiedemann C
      Biomol NMR Assign 2020, 14(2), 163-8
    • Cysteines and Disulfide Bonds as Structure-Forming Units: Insights From Different Domains of Life and the Potential for Characterization by NMR.
      Wiedemann C, Kumar A, Lang A, Ohlenschläger O
      Front Chem 2020, 8, 280

    Publications 2019:

    • Structural investigations on heme-interacting proteins = Strukturelle Untersuchung an Häm-bindenden Proteinen
      Kumar A
      Dissertation 2019, Jena, Germany
    • NMR experiments on the transient interaction of the intrinsically disordered N-terminal peptide of cystathionine-β-synthase with heme.
      Kumar A, Bellstedt P, Wiedemann C, Wißbrock A, Imhof D, Ramachandran R, Ohlenschläger O
      J Magn Reson 2019, 308, 106561
    • 1 H, 13 C, and 15 N resonance assignments of the cytokine interleukin-36β isoform-2.
      Kumar A, Wißbrock A, Bellstedt P, Lang A, Ramachandran R, Wiedemann C, Imhof D, Ohlenschläger O
      Biomol NMR Assign 2019, 13(1), 155-61
    • Structural insights into heme binding to IL-36α proinflammatory cytokine.
      Wißbrock* A, Goradia* NB, Kumar A, Paul George AA, Kühl T, Bellstedt P, Ramachandran R, Hoffmann P, Galler K, Popp J, Neugebauer U, Hampel K, Zimmermann B, Adam S, Wiendl M, Krönke G, Hamza I, Heinemann SH, Frey S, Hueber AJ, Ohlenschläger** O, Imhof** D
      Sci Rep 2019, 9(1), 16893 * equal contribution, ** co-corresponding authors

    Publications 2018:

    • Heme interaction of the intrinsically disordered N-terminal peptide segment of human cystathionine-β-synthase.
      Kumar A, Wißbrock A, Goradia N, Bellstedt P, Ramachandran R, Imhof D, Ohlenschläger O
      Sci Rep 2018, 8(1), 2474