Yuan Meng

China
Phone: +49 3641 656749
Email: yuan.meng@leibniz-fli.de

Generation of mutants in epigenetic modifier genes in shoprt-lived killifish Nothobranchius furzeri

Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Englert Research Group

First Supervisor:

Christoph Englert (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Publications 2020:

  • Vascular endothelium-targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model.
    Sun S, Qin W, Tang X, Meng Y, Hu W, Zhang S, Qian M, Liu Z, Cao X, Pang Q, Zhao B, Wang Z, Zhou Z, Liu B
    Sci Adv 2020, 6(8), eaay5556
  • HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration.
    Tang X, Li G, Su F, Cai Y, Shi L, Meng Y, Liu Z, Sun J, Wang M, Qian M, Wang Z, Xu X, Cheng YX, Zhu WG, Liu B
    Nucleic Acids Res 2020, 48(6), 2912-23
  • PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson-Gilford progeria syndrome.
    Wang M, Wang L, Qian M, Tang X, Liu Z, Lai Y, Ao Y, Huang Y, Meng Y, Shi L, Peng L, Cao X, Wang Z, Qin B, Liu B
    Aging Cell 2020, 19(6), e13147