Domenico Di Fraia
Italy
Phone: +49 3641 656856
Email: domenico.difraia@leibniz-fli.de
Email: domenico.difraia@leibniz-fli.de
Computational approaches to study organelle and protein complex composition in aging
Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Ori Research Group
First Supervisor:
Alessandro Ori (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))Co – Supervisor(s):
Steve Hoffmann (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))Publications 2022:
- ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies
Bartolome A, Heiby* JC, Dau* T, Di Fraia D, Heinze I, Kirkpatrick JM, Ori A
bioRxiv 2022, https://doi.org/10.1101/2022.08. * equal contribution - Conserved exchange of paralog proteins during neuronal differentiation.
Di Fraia D, Anitei M, Mackmull MT, Parca L, Behrendt L, Andres-Pons A, Gilmour D, Helmer Citterich M, Kaether C, Beck M, Ori A
Life Sci Alliance 2022, 5(6)
Publications 2020:
- Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction.
Gebert N, Cheng CW, Kirkpatrick JM, Di Fraia D, Yun J, Schädel P, Pace S, Garside GB, Werz O, Rudolph KL, Jasper H, Yilmaz ÖH, Ori A
Cell Rep 2020, 31(4), 107565 - Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation.
Kelmer Sacramento* E, Kirkpatrick* JM, Mazzetto* M, Baumgart M, Bartolome A, Di Sanzo S, Caterino C, Sanguanini M, Papaevgeniou N, Lefaki M, Childs D, Bagnoli S, Terzibasi Tozzini E, Di Fraia D, Romanov N, Sudmant PH, Huber W, Chondrogianni N, Vendruscolo M, Cellerino** A, Ori** A
Mol Syst Biol 2020, 16(6), e9596 * equal contribution, ** co-corresponding authors
