Seyed Mohammad Mahdi Rasa

Islamic Republic of Iran
Phone: +49 3641 656627
Email: mahdi.rasa@leibniz-fli.de

Characterization of the transcriptome, the epigenome, and the microbiome during aging: dietary restriction ameliorates inflammaging

Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Neri Research Group

First Supervisor:

Francesco Neri (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Co – Supervisor(s):

Karl Lenhard Rudolph (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Publications 2021:

  • Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
    Freter R, Falletta P, Omrani O, Rasa M, Herbert K, Annunziata F, Minetti A, Krepelova A, Adam L, Käppel S, Rüdiger T, Wang ZQ, Goding** CR, Neri** F
    Nat Commun 2021, 12(1), 3318 ** co-corresponding authors
  • HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration.
    Tapias* A, Lázaro* D, Yin* BK, Rasa SMM, Krepelova A, Kelmer Sacramento E, Grigaravicius P, Koch P, Kirkpatrick J, Ori A, Neri F, Wang ZQ
    Elife 2021, 10, e61531 * equal contribution

Publications 2019:

  • Aging Triggers H3K27 Trimethylation Hoarding in the Chromatin of Nothobranchius furzeri Skeletal Muscle.
    Cencioni* C, Heid* J, Krepelova A, Rasa SMM, Kuenne C, Guenther S, Baumgart M, Cellerino A, Neri F, Spallotta** F, Gaetano** C
    Cells 2019, 8(10) * equal contribution, ** co-senior authors
  • Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.
    Chen Z, Amro EM, Becker F, Hölzer M, Rasa SMM, Njeru SN, Han B, Di Sanzo S, Chen Y, Tang D, Tao S, Haenold R, Groth M, Romanov VS, Kirkpatrick JM, Kraus JM, Kestler HA, Marz M, Ori A, Neri F, Morita** Y, Rudolph** KL
    J Exp Med 2019, 216(1), 152-75 ** co-corresponding authors