Simone Di Sanzo

Phone: +49 3641 656856

Investigating the relationship between protein glycation and aggregation in stem cells and tissues

Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Ori Research Group

First Supervisor:

Alessandro Ori (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Co – Supervisor(s):

Karl Lenhard Rudolph (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Publications 2020:

  • Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation.
    Kelmer Sacramento* E, Kirkpatrick* JM, Mazzetto* M, Baumgart M, Bartolome A, Di Sanzo S, Caterino C, Sanguanini M, Papaevgeniou N, Lefaki M, Childs D, Bagnoli S, Terzibasi Tozzini E, Di Fraia D, Romanov N, Sudmant PH, Huber W, Chondrogianni N, Vendruscolo M, Cellerino** A, Ori** A
    Mol Syst Biol 2020, 16(6), e9596 * equal contribution, ** co-corresponding authors
  • Publications 2019:

    • Quantitation of Reactive Acyl-CoA Species Mediated Protein Acylation by HPLC-MS/MS.
      Baldensperger T, Simone DS, Ori A, Glomb MA
      Anal Chem 2019, 91(19), 12336-43
    • Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.
      Chen Z, Amro EM, Becker F, Hölzer M, Rasa SMM, Njeru SN, Han B, Di Sanzo S, Chen Y, Tang D, Tao S, Haenold R, Groth M, Romanov VS, Kirkpatrick JM, Kraus JM, Kestler HA, Marz M, Ori A, Neri F, Morita** Y, Rudolph** KL
      J Exp Med 2019, 216(1), 152-75 ** co-corresponding authors
    • Increased Expression of Immature Mannose-Containing Glycoproteins and Sialic Acid in Aged Mouse Brains.
      Simon F, Bork K, Gnanapragassam VS, Baldensperger T, Glomb MA, Di Sanzo S, Ori A, Horstkorte R
      Int J Mol Sci 2019, 20(24)

Scientific CV

July 2016 - December 2016       Research assistant - HiWi student in CF Proteomics
Leibniz Institute on Aging - FLI, Beutenbergstraße 11, 07745 Jena
March 2012 - July 2013       Technical researcher in mass spectrometry-MALDI-TOF
University of Milano-Bicocca, Via Cadore 48, Monza Milan
January 2009 - January 2010       Laboratory Technician
University of Milano, Ospedale Maggiore Policlinico Fondazione IRCCS Milan
2010 - 2013       Master’s Degree of Science in Medical Biotechnologies at University of Milano-Bicocca
2007 – 2010       Bachelor Degree of Science in Biomedical Laboratory Methods at University of Milan