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David Lazero Pellon

Spain

Role of epigenetic modulation in neuron migration and impairment of adult neuroregeneration

Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Wang Research Group

First Supervisor:

Zhao-Qi Wang (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Publications 2023:

  • TRRAP-mediated acetylation on Sp1 regulates adult neurogenesis.
    Yin BK, Lázaro D, Wang ZQ
    Comput Struct Biotechnol J 2023, 21, 472

    • Publications 2021:

    • HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration.
      Tapias* A, Lázaro* D, Yin* BK, Rasa SMM, Krepelova A, Kelmer Sacramento E, Grigaravicius P, Koch P, Kirkpatrick J, Ori A, Neri F, Wang ZQ
      Elife 2021, 10, e61531 * equal contribution

    Publications 2017:

    • Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.
      Schuhwerk H, Bruhn C, Siniuk K, Min W, Erener S, Grigaravicius P, Krüger A, Ferrari E, Zubel T, Lazaro D, Monajembashi S, Kiesow K, Kroll T, Bürkle A, Mangerich A, Hottiger M, Wang ZQ
      Nucleic Acids Res 2017, 45(19), 11174-92