Yuan Meng
China
Phone: +49 3641 656749
Single-cell sequencing analysis unravels genes/pathways regulating vertebrate aging
Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Englert Research Group
First Supervisor:
Christoph Englert (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)), Baohua Liu (Shenzhen University)Publications 2023:
- CD133+ endothelial-like stem cells restore neovascularization and promote longevity in progeroid and naturally aged mice.
Sun* S, Meng* Y, Li* M, Tang X, Hu W, Wu W, Li G, Pang Q, Wang W, Liu B
Nat Aging 2023, 3(11), 1401-14 * equal contribution - Vascular endothelium-targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model.
Sun S, Qin W, Tang X, Meng Y, Hu W, Zhang S, Qian M, Liu Z, Cao X, Pang Q, Zhao B, Wang Z, Zhou Z, Liu B
Sci Adv 2020, 6(8), eaay5556 - HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration.
Tang X, Li G, Su F, Cai Y, Shi L, Meng Y, Liu Z, Sun J, Wang M, Qian M, Wang Z, Xu X, Cheng YX, Zhu WG, Liu B
Nucleic Acids Res 2020, 48(6), 2912-23 - PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson-Gilford progeria syndrome.
Wang M, Wang L, Qian M, Tang X, Liu Z, Lai Y, Ao Y, Huang Y, Meng Y, Shi L, Peng L, Cao X, Wang Z, Qin B, Liu B
Aging Cell 2020, 19(6), e13147
