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Xingxuan Wu

China

UFMylation of CDK5RAP2/MCPH3 regulates mitosis

Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Wang Research Group

First Supervisor:

Zhao-Qi Wang (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Co – Supervisor(s):

Helmut Pospiech (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Publications 2023:

  • The neurological and non-neurological roles of the primary microcephaly-associated protein ASPM.
    Wu X, Li Z, Wang ZQ, Xu X
    Front Neurosci 2023, 17, 1242448

    • Publications 2022:

    • ASPM promotes ATR-CHK1 activation and stabilizes stalled replication forks in response to replication stress.
      Wu* X, Xu* S, Wang P, Wang ZQ, Chen H, Xu X, Peng B
      Proc Natl Acad Sci U S A 2022, 119(40), e2203783119 * equal contribution

    Publications 2021:

    • ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability.
      Xu* S, Wu* X, Wang P, Cao SL, Peng B, Xu X
      iScience 2021, 24(6), 102534 * equal contribution