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Publications with the contribution of LGSA PhD candidates

The goal of a PhD thesis program is to publish at least one first-author paper in an international peer-reviewed journal. We are very happy that our young researchers highly contribute to the publication record of the participating institutions.

2025

  • A fluorescent folding reporter uncovers myosin misfolding as a driver of Hypertrophic Cardiomyopathy
    Arnese R, Julian Dexheimer P, Escobar-Doncel B, Krüger L, Adhikari G, Krpan N, Sehr D, Kley J, Deszcz L, Meinhart A, Kirstein J, Clausen T
    bioRxiv 2025, https://doi.org/10.1101/2025.02.
  • Placental epigenetic clocks derived from crowdsourcing: Implications for the study of accelerated aging in obstetrics.
    Bhatti G, Sufriyana H, Romero R, Patel T, Tekola-Ayele F, Alsaggaf I, Gomez-Lopez N, Su ECY, Done B, Hoffmann S, van Bömmel A, Wan C, Albrecht J, Novak C, DREAM Placenta Clock Challenge Consortium, Chaiworapongsa T, Sirota M, Aghaeepour N, Stolovitzky G, Bryant DR, Tarca AL
    iScience 2025, 28(8), 113181
  • HSP-1-Specific Nanobodies Alter Chaperone Function in vitro and in vivo
    D.Urban N, Gharat K, J.Mattiola Z, Scheutzow A, Klaiss A, Tabler S, W.Huffaker A, Grootveld M, E.Skinner M, Kirstein J, C.Truttmann M
    bioRxiv 2025, https://doi.org/10.1101/2025.08.
  • Altered translation elongation contributes to key hallmarks of aging in the killifish brain.
    Di Fraia* D, Marino* A, Lee* JH, Kelmer Sacramento E, Baumgart M, Bagnoli S, Balla T, Schalk F, Kamrad S, Guan R, Caterino C, Giannuzzi C, Tomaz da Silva P, Sahu AK, Gut H, Siano G, Tiessen M, Terzibasi-Tozzini E, Fornasiero EF, Gagneur J, Englert C, Patil KR, Correia-Melo C, Nedialkova DD, Frydman** J, Cellerino** A, Ori** A
    Science 2025, 389(6759), eadk3079 * equal contribution, ** co-corresponding authors
  • Destabilization of rRNA genes due to Myc-driven hyperactivation is thwarted by promoter silencing in B cell lymphoma
    Eberhardt A
    Dissertation 2025, Jena, Germany
  • Distinct Effects of Aging and Klotho Deletion on the Choroid Plexus
    Fanaei-Kahrani Z, Patel T, Valkova C, Gloria A, Wagner J, Heuer H, Schwaninger M, Hofmann S, Bauer R, Kaether C
    bioRxiv 2025, https://doi.org/10.1101/2025.11.
  • Exploring the effects of amyloid beta (Aß) and Tau aggregation on neuronal activity and proteotoxicity in C. elegans
    Hirsch F
    Dissertation 2025, Bremen, Germany
  • Impairment of neuronal activity occurs at the early stages of the aggregation cascade of Aβ1-42 and mutant Tau
    Hirsch F, Läubli N, Kelkar A, Sleiman M, Woitzat Y, Gallrein C, Gumz V, Kaur Kalsi G, Fernandez-Villegas A, Kaminski Schierle G, Kirstein J
    bioRxiv 2025, https://doi.org/10.1101/2025.07.
  • Transient YAP/TAZ inhibition exposes therapeutic vulnerabilities in advanced cancers
    Jessen M, Kim K, Tollot-Wegner M, Cindric Vranesic A, Dönmez C, Junker C, Lehmann T, Khandelwal A, Kurlishchuk Y, Hünniger T, Ritter C, Di Napoli E, Krishnan Murali S, Buck V, Muth S, T.Tang T, Rosenwald A, Radsak M, Inverso D, Paciello O, von Eyss B
    bioRxiv 2025, https://doi.org/10.1101/2025.07.
  • Iron homeostasis and cell clonality drive cancer-associated intestinal DNA methylation drift in aging.
    Krepelova A, Rasa M, Annunziata F, Lu J, Giannuzzi C, Omrani O, Wyart E, Porporato PE, Ansari I, Bilenko D, Bergman Y, Neri F
    Nat Aging 2025 (epub ahead of print)