Alberto Minetti

Publications 2025:

• Oxidative stress causes a reversible decrease of deubiquitylases activity in old vertebrate brains
  Kumar Sahu A, Minetti A, Di Fraia D, Marino A, Rainer Winterhalter P, Giustarini D, Simm A, Neri F, Galvagni F, Gerhardt C, Pfirrmann** T, Ori** A
  bioRxiv 2025, https://doi.org/10.1101/2025.08. ** co-corresponding authors
  
• Aging and diet alter the protein ubiquitylation landscape in the mouse brain.
  Marino* A, Di Fraia* D, Panfilova D, Sahu AK, Minetti A, Omrani O, Cirri E, Ori A
  Nat Commun 2025, 16(1), 5266 * equal contribution
  
• Polyamines support intestinal epithelium regeneration in aging by regulating protein homeostasis
  Minetti A
  Dissertation 2025, Jena, Germany
  
• Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis.
  Minetti* A, Omrani* O, Brenner C, Cansiz F, Imada S, Rösler J, Khawaled S, Allies G, Meckelmann SW, Gebert N, Heinze I, Rahnis N, Lu J, Spengler K, Rasa M, Cirri E, Heller R, Yilmaz Ö, Tasdogan A, Neri** F, Ori** A
  Nat Cell Biol 2025 (epub ahead of print) * equal contribution, ** co-senior authors
  
• N-acetyl-l-cysteine ethyl ester (NACET) induces the transcription factor NRF2 and prevents retinal aging and diabetic retinopathy.
  Realini G, Amato R, Rasa M, Ceccatelli R, Cannavale A, Bottoni L, Marchini F, Minetti A, Giustarini D, Canovai A, Melecchi A, Elia I, Krepelova A, Annunziata F, Cammalleri M, Rossi R, Tosi GM, Orlandini M, Chiariello M, Neri F, Dal Monte M, Galvagni F
  Redox Biol 2025 (epub ahead of print)
  

Publications 2024:

• Quantitative mapping of proteasome interactomes and substrates using ProteasomeID.
  Bartolome A, Heiby* JC, Di Fraia* D, Heinze I, Knaudt H, Spaeth E, Omrani O, Minetti A, Hofmann M, Kirkpatrick JM, Dau** T, Ori** A
  Elife 2024, 13, RP93256 * equal contribution, ** co-corresponding authors
  
• NRF2 activation by cysteine as a survival mechanism for triple-negative breast cancer cells.
  Bottoni L, Minetti A, Realini G, Pio E, Giustarini D, Rossi R, Rocchio C, Franci L, Salvini L, Catona O, D'Aurizio R, Rasa M, Giurisato E, Neri F, Orlandini M, Chiariello M, Galvagni F
  Oncogene 2024, 43(22), 1701-13
  
• Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis
  Minetti A, Omrani O, Brenner C, Allies G, Imada S, Rösler J, Khawaled S, Cansiz F, W.Meckelmann S, Gebert N, Heinze I, Lu J, Spengler K, Rasa M, Heller R, Yilmaz O, Tasdogan A, Neri F, Ori A
  bioRxiv 2024, https://doi.org/10.1101/2024.07.
  
• Leiomodin 1 promotes myogenic differentiation by modulating Sirtuin 1
  Späth* E, C.Schüler* S, Heinze I, Dau T, Minetti A, Hofmann M, von Maltzahn** J, Ori** A
  bioRxiv 2024, https://doi.org/10.1101/2024.03. * equal contribution, ** co-corresponding authors
  

Publications 2022:

• Paneth cells drive intestinal stem cell competition and clonality in aging and calorie restriction
  Annunziata F, Rasa SMM, Krepelova A, Lu J, Minetti A, Omrani O, Nunna S, Adam L, Käppel S, Neri F
  Eur J Cell Biol 2022, 101(4), 151282
  

Publications 2021:

• Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
  Freter R, Falletta P, Omrani O, Rasa M, Herbert K, Annunziata F, Minetti A, Krepelova A, Adam L, Käppel S, Rüdiger T, Wang ZQ, Goding** CR, Neri** F
  Nat Commun 2021, 12(1), 3318 ** co-corresponding authors