Saravanakkumar Chennappan


Moderate H-Ras activation decreases the health span in Costello Syndrome mouse model: novel H-RasG12V – driven advanced aging phenotype

Friedrich Schiller University Jena (FSU) - Faculty of Biology and Pharmacy
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Cirstea Research Group

First Supervisor:

Ion Cristian Cirstea (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Publications 2017:

  • Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model
    Chennappan S, Schulze T, Cirstea IC
    Molecular Life 2017, 1(1), 3-14