Publications 2018:

  • Whither systems medicine?
    Apweiler R, Beissbarth T, Berthold MR, Blüthgen N, Burmeister Y, Dammann O, Deutsch A, Feuerhake F, Franke A, Hasenauer J, Hoffmann S, Höfer T, Jansen PL, Kaderali L, Klingmüller U, Koch I, Kohlbacher O, Kuepfer L, Lammert F, Maier D, Pfeifer N, Radde N, Rehm M, Roeder I, Saez-Rodriguez J, Sax U, Schmeck B, Schuppert A, Seilheimer B, Theis FJ, Vera J, Wolkenhauer O
    Exp Mol Med 2018, 50(3), e453
  • Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.
    Aramillo Irizar P, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C
    Nat Commun 2018, 9(1), 327
  • SETD1A protects HSCs from activation-induced functional decline in vivo.
    Arndt K, Kranz A, Fohgrub J, Jolly A, Bledau AS, Di Virgilio M, Lesche M, Dahl A, Höfer T, Stewart AF, Waskow C
    Blood 2018, 131(12), 1311-24
  • Kidney regeneration in fish.
    Bates T, Naumann U, Hoppe B, Englert C
    Int J Dev Biol 2018, 62(6-7-8), 419-29
  • Analysis of lncRNA-Protein Interactions by RNA-Protein Pull-Down Assays and RNA Immunoprecipitation (RIP).
    Bierhoff H
    Methods Mol Biol 2018, 1686, 241-50
  • Spatial tissue proteomics quantifies inter- and intra-tumor heterogeneity in hepatocellular carcinoma.
    Buczak* K, Ori* A, Kirkpatrick JM, Holzer K, Dauch D, Roessler S, Endris V, Lasitschka F, Parca L, Schmidt A, Zender L, Schirmacher P, Krijgsveld J, Singer** S, Beck** M
    Mol Cell Proteomics 2018, 17(4), 810-25 * equal contribution, ** co-corresponding authors
  • Computational pan-genomics: status, promises and challenges.
    Computational PGC, Marschall T, Marz M, Abeel T, Dijkstra L, Dutilh BE, Ghaffaari A, Kersey P, Kloosterman WP, Mäkinen V, Novak AM, Paten B, Porubsky D, Rivals E, Alkan C, Baaijens JA, De Bakker PIW, Boeva V, Bonnal RJP, Chiaromonte F, Chikhi R, Ciccarelli FD, Cijvat R, Datema E, Van Duijn CM, Eichler EE, Ernst C, Eskin E, Garrison E, El-Kebir M, Klau GW, Korbel JO, Lameijer EW, Langmead B, Martin M, Medvedev P, Mu JC, Neerincx P, Ouwens K, Peterlongo P, Pisanti N, Rahmann S, Raphael B, Reinert K, de Ridder D, de Ridder J, Schlesner M, Schulz-Trieglaff O, Sanders AD, Sheikhizadeh S, Shneider C, Smit S, Valenzuela D, Wang J, Wessels L, Zhang Y, Guryev V, Vandin F, Ye K, Schönhuth A
    Brief Bioinform 2018, 19(1), 118-35
  • Sequential use of milk and bovine serum albumin for streptavidin-probed western blot.
    Cui Y, Ma L
    Biotechniques 2018, 65(3), 125-6
  • X-ray Structures of the Proprotein Convertase Furin Bound with Substrate Analogue Inhibitors Reveal Substrate Specificity Determinants beyond the S4 Pocket.
    Dahms SO, Hardes K, Steinmetzer T, Than ME
    Biochemistry 2018, 57(6), 925-34
  • DIEGO: Detection of Differential Alternative Splicing using Aitchison's Geometry.
    Doose G, Bernhart SH, Wagener R, Hoffmann S
    Bioinformatics 2018, 34(6), 1066-8
  • Cellular and epigenetic drivers of stem cell ageing.
    Ermolaeva M, Neri F, Ori A, Rudolph KL
    Nat Rev Mol Cell Biol 2018, 19(9), 594-610
  • On the S-layer of Thermus thermophilus and the assembling of its main protein SlpA.
    Farci D, Farci SF, Esposito F, Tramontano E, Kirkpatrick J, Piano D
    Biochim Biophys Acta 2018, 1860(8), 1554-62
  • 2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis.
    Fisher MJ, Belzberg AJ, de Blank P, De Raedt T, Elefteriou F, Ferner RE, Giovannini M, Harris GJ, Kalamarides M, Karajannis MA, Kim A, Lázaro C, Le LQ, Li W, Listernick R, Martin S, Morrison H, Pasmant E, Ratner N, Schorry E, Ullrich NJ, Viskochil D, Weiss B, Widemann BC, Zhu Y, Bakker A, Serra E
    Am J Med Genet A 2018, 176(5), 1258-69
  • Integrative analysis of differentially expressed genes and miRNAs predicts complex T3-mediated protective circuits in a rat model of cardiac ischemia reperfusion.
    Forini F, Nicolini G, Kusmic C, D'Aurizio R, Rizzo M, Baumgart M, Groth M, Doccini S, Iervasi G, Pitto L
    Sci Rep 2018, 8(1), 13870
  • The eukaryotic linear motif resource - 2018 update.
    Gouw M, Michael S, Sámano-Sánchez H, Kumar M, Zeke A, Lang B, Bely B, Chemes LB, Davey NE, Deng Z, Diella F, Gürth CM, Huber AK, Kleinsorg S, Schlegel LS, Palopoli N, Roey KV, Altenberg B, Reményi A, Dinkel H, Gibson TJ
    Nucleic Acids Res 2018, 46(D1), D428-34
  • Effects of allelic variations in the human Myxovirus resistance protein A on its antiviral activity.
    Graf L, Dick A, Sendker F, Barth E, Marz M, Daumke O, Kochs G
    J Biol Chem 2018, 293(9), 3056-72
  • Rapid proteotyping reveals cancer biology and drug response determinants in the NCI-60 cells
    Guo* T, Luna* A, Koh* CC, Rajapakse* V, Wu Z, Menden MP, Cheng Y, Calzone L, Martignetti L, Ori A, Iskar M, Gillet P, Zhong Q, Varma S, Schmitt U, Qiu P, Sun Y, Zhu Y, Wild P, Mathew G, Bork P, Beck M, Saez-Rodriguez J, Reinhold W, Sander C, Pommier Y, Aebersold R
    bioRxiv 2018, * equal contribution
  • Molecular mechanisms of photoadaptation of photosystem I supercomplex of in an evolutionary cyanobacterial/algal intermediate.
    Haniewicz P, Abram M, Nosek L, Kirkpatrick J, El-Mohsnawy E, Janna Olmos JD, Kouril R, Kargul JM
    Plant Physiol 2018, 176(2), 1433-51
  • Managing myeloproliferative neoplasms evidence based on the ELN treatment recommendations 2018.
    Heidel FH, Gale RP, Hochhaus A
    Leukemia 2018, 32(5), 1055-6
  • Conformational µ-conotoxin PIIIA isomers revisited: The impact of cysteine pairing on disulfide bond assignment and structure elucidation.
    Heimer P, Tietze AA, Bäuml CA, Resemann A, Mayer FJ, Suckau D, Ohlenschläger O, Tietze D, Imhof D
    Anal Chem 2018, 90(5), 3321-7
  • Retinal S-opsin dominance in Ansell's mole-rats (Fukomys anselli) is a consequence of naturally low serum thyroxine.
    Henning Y, Mladěnková N, Burda H, Szafranski* K, Begall* S
    Sci Rep 2018, 8(1), 4337 * equal contribution
  • The fate of ribosomal RNA genes in spontaneous polyploid dogrose hybrids (Rosa L. sect. Caninae (DC.) Ser.) exhibiting non-symmetrical meiosis.
    Herklotz V, Kovařík A, Lunerová J, Lippitsch S, Groth M, Ritz CM
    Plant J 2018, 94(1), 77-90
  • sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca2+ homeostasis and CREB1-signaling
    Hesse R, von Einem B, Wagner F, Bott P, Schwanzar D, Jackson RJ, Föhr KJ, Lausser L, Kroker KS, Proepper C, Walther P, Kestler HA, Spires-Jones TL, Boeckers T, Rosenbrock H, von Arnim CAF
    Exp Neurol 2018, 304, 1-13
  • Multiple roots of fruiting body formation in Amoebozoa.
    Hillmann F, Forbes G, Novohradská S, Ferling I, Riege K, Groth M, Westermann M, Marz M, Spaller T, Winckler T, Schaap P, Glöckner G
    Genome Biol Evol 2018, 10(2), 591-606
  • Multimodal Light Microscopy Approaches to Reveal Structural and Functional Properties of Promyelocytic Leukemia Nuclear Bodies.
    Hoischen C, Monajembashi S, Weisshart K, Hemmerich P
    Front Oncol 2018, 8, 125
  • CENP-C/H/I/K/M/T/W/N/L and hMis12 but not CENP-S/X participate in complex formation in the nucleoplasm of living human interphase cells outside centromeres.
    Hoischen* C, Yavas* S, Wohland T, Diekmann S
    PLoS One 2018, 13(3), e0192572 * equal contribution
  • The microenvironment of naked mole-rat burrows in East Africa
    Holtze S, Braude S, Lemma A, Koch R, Morhart M, Szafranski K, Platzer M, Alemayehu F, Goeritz F, Hildebrandt TB
    Afr J Ecol 2018, 56(2), 279-89
  • Virologists-Heroes need weapons.
    Hufsky F, Ibrahim B, Beer M, Deng L, Mercier PL, McMahon DP, Palmarini M, Thiel V, Marz M
    PLoS Pathog 2018, 14(2), e1006771
  • Bioinformatics Meets Virology: The European Virus Bioinformatics Center's Second Annual Meeting.
    Ibrahim B, Arkhipova K, Andeweg AC, Posada-Céspedes S, Enault F, Gruber A, Koonin EV, Kupczok A, Lemey P, McHardy AC, McMahon DP, Pickett BE, Robertson DL, Scheuermann RH, Zhernakova A, Zwart MP, Schönhuth A, Dutilh BE, Marz M
    Viruses 2018, 10(5)
  • Synthesis and biochemical evaluation of two novel N-hydroxyalkylated cyclosporin A analogs.
    Kahlert V, Prell E, Ohlenschläger O, Melesina J, Schumann M, Lücke C, Fischer G, Malešević M
    Org Biomol Chem 2018, 16(23), 4338-49
  • Transduction and transfection of difficult-to-transfect cells: Systematic attempts for the transfection of protozoa Leishmania.
    Keller AA, Scheiding B, Breitling R, Licht A, Hemmerich P, Lorkowski S, Reissmann S
    J Cell Biochem 2018 (epub ahead of print)
  • Big data and precision medicine: challenges and strategies with healthcare data
    Kraus JM, Lausser L, Kuhn P, Jobst F, Bock M, Halanke C, Hummel M, Heuschmann P, Kestler HA
    Int J Data Sci Anal 2018
  • Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma.
    Lee S, Liu P, Teinturier R, Jakob J, Tschaffon M, Tasdogan A, Wittig R, Hoeller S, Baumhoer D, Frappart L, Vettorazzi S, Bertolino P, Zhang C, Tuckermann J
    Oncogene 2018, 37(5), 616-26
  • Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis.
    Li J, Song P, Jiang T, Dai D, Wang H, Sun J, Zhu L, Xu W, Feng L, Shin VY, Morrison H, Wang X, Jin H
    Mol Ther 2018, 26(7), 1828-39
  • Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair.
    Lopez-Baez JC, Simpson DJ, LLeras Forero L, Zeng Z, Brunsdon H, Salzano A, Brombin A, Wyatt C, Rybski W, Huitema LFA, Dale RM, Kawakami K, Englert C, Chandra T, Schulte-Merker S, Hastie ND, Patton EE
    Elife 2018, 7, e30657
  • Cystatin A suppresses tumor cell growth through inhibiting epithelial to mesenchymal transition in human lung cancer.
    Ma Y, Chen Y, Li Y, Grün K, Berndt A, Zhou Z, Petersen I
    Oncotarget 2018, 9(18), 14084-98
  • Structural and functional conservation of cis-acting RNA elements in coronavirus 5'-terminal genome regions.
    Madhugiri R, Karl N, Petersen D, Lamkiewicz K, Fricke M, Wend U, Scheuer R, Marz M, Ziebuhr J
    Virology 2018, 517, 44-55
  • Internal tandem duplication mutations in the tyrosine kinase domain of FLT3 display a higher oncogenic potential than the activation loop D835Y mutation.
    Marhäll A, Heidel F, Fischer T, Rönnstrand L
    Ann Hematol 2018, 97(5), 773-80
  • The sirtuin 1/2 inhibitor tenovin-1 induces a nonlinear apoptosis-inducing factor-dependent cell death in a p53 null Ewing's sarcoma cell line.
    Marx C, Marx-Blümel L, Lindig N, Thierbach R, Hoelzer D, Becker S, Wittig S, Lehmann R, Slevogt H, Heinzel T, Wang ZQ, Beck JF, Sonnemann J
    Invest New Drugs 2018, 36(3), 396-406
  • Reduced expression of C/EBPβ-LIP extends health- and lifespan in mice.
    Müller* C, Zidek* LM, Ackermann T, de Jong T, Liu P, Kliche V, Zaini MA, Kortman G, Harkema L, Verbeek DS, Tuckermann JP, von Maltzahn J, de Bruin A, Guryev V, Wang ZQ, Calkhoven CF
    Elife 2018, 7, e34985 * equal contribution
  • Dispersion/reaggregation in early development of annual killifishes: Phylogenetic distribution and evolutionary significance of a unique feature.
    Naumann B, Englert C
    Dev Biol 2018, 442(1), 69-79
  • Efficacy and safety of ruxolitinib in intermediate-1 IPSS risk myelofibrosis patients: Results from an independent study.
    Palandri F, Tiribelli M, Benevolo G, Tieghi A, Cavazzini F, Breccia M, Bergamaschi M, Sgherza N, Polverelli N, Crugnola M, Isidori A, Binotto G, Heidel FH, Buccisano F, Martino B, Latagliata R, Spinsanti M, Kallenberg L, Palumbo GA, Abruzzese E, Scaffidi L, Cuneo A, Cavo M, Vianelli N, Bonifacio M
    Hematol Oncol 2018, 36(1), 285-90
  • Quantifying compartment-associated variations of protein abundance in proteomics data.
    Parca L, Beck M, Bork P, Ori A
    Mol Syst Biol 2018, 14(7), e8131
  • Dysregulation of chemokine receptor expression and function in leukocytes from ALS patients.
    Perner C, Perner F, Stubendorff B, Förster M, Witte OW, Heidel FH, Prell T, Grosskreutz J
    J Neuroinflammation 2018, 15(1), 99
  • The Pseudogenes of Barley.
    Prade VM, Gundlach H, Twardziok S, Chapman B, Tan C, Langridge P, Schulman AH, Stein N, Waugh R, Zhang G, Platzer M, Li C, Spannagl M, Mayer KFX
    Plant J 2018, 93(3), 502-14
  • Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.
    Prestipino A, Emhardt AJ, Aumann K, O'Sullivan D, Gorantla SP, Duquesne S, Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, Veratti P, Hettich M, Niedermann G, Bartholomä M, Shoumariyeh K, Jutzi JS, Wehrle J, Dierks C, Becker H, Schmitt-Graeff A, Follo M, Pfeifer D, Rohr J, Fuchs S, Ehl S, Hartl FA, Minguet S, Miething C, Heidel FH, Kröger N, Triviai I, Brummer T, Finke J, Illert AL, Ruggiero E, Bonini C, Duyster J, Pahl HL, Lane SW, Hill GR, Blazar BR, von Bubnoff N, Pearce EL, Zeiser R
    SCI TRANSL MED 2018, 10(429)
  • Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity.
    Prigent J, Jarossay A, Planchais C, Eden C, Dufloo J, Kök A, Lorin V, Vratskikh O, Couderc T, Bruel T, Schwartz O, Seaman MS, Ohlenschläger O, Dimitrov JD, Mouquet H
    Cell Rep 2018, 23(9), 2568-81
  • RBFOX2 and alternative splicing in B-cell lymphoma.
    Quentmeier H, Pommerenke C, Bernhart SH, Dirks WG, Hauer V, Hoffmann S, Nagel S, Siebert R, Uphoff CC, Zaborski M, Drexler HG, ICGC MMML-Seq Consortium
    Blood Cancer J 2018, 8(8), 77
  • Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis.
    Ravichandran M, Priebe S, Grigolon G, Rozanov L, Groth M, Laube B, Guthke R, Platzer M, Zarse K, Ristow M
    Cell Metab 2018, 27(4), 914-25
  • Haplotypes composed of minor frequency single nucleotide polymorphism of tnf gene protect from progression into sepsis: A study using the new sepsis classification.
    Retsas T, Huse K, Lazaridis LD, Karampela N, Bauer M, Platzer M, Kolonia V, Papageorgiou E, Giamarellos-Bourboulis EJ, Dimopoulos G
    Int J Infect Dis 2018, 67, 102-6
  • Neuropathies in the setting of Neurofibromatosis tumor syndromes: Complexities and opportunities.
    Schulz A, Grafe P, Hagel C, Bäumer P, Morrison H, Mautner VF, Farschtschi S
    Exp Neurol 2018, 299(Pt B), 334-44
  • Aspergillus fumigatus conidial metalloprotease Mep1p cleaves host complement proteins.
    Shende R, Wong SSW, Rapole S, Beau R, Ibrahim-Granet O, Monod M, Gührs KH, Pal JK, Latgé JP, Madan T, Aimanianda V, Sahu A
    J Biol Chem 2018 (epub ahead of print)
  • The Definition of Open Reading Frame Revisited.
    Sieber P, Platzer M, Schuster S
    Trends Genet 2018, 34(3), 167-70
  • A Boolean network of the crosstalk between IGF and Wnt signaling in aging satellite cells.
    Siegle* L, Schwab* JD, Kühlwein* SD, Lausser L, Tümpel S, Pfister AS, Kühl** M, Kestler** HA
    PLoS One 2018, 13(3), e0195126 * equal contribution, ** co-senior authors
  • LSD1 (KDM1A)-independent effects of the LSD1 inhibitor SP2509 in cancer cells.
    Sonnemann J, Zimmermann M, Marx C, Ebert F, Becker S, Lauterjung ML, Beck JF
    Br J Haematol 2018 (epub ahead of print)
  • The microRNA miR-21 Is a Mediator of FGF8 Action on Cortical COUP-TFI Translation.
    Terrigno M, Bertacchi M, Pandolfini L, Baumgart M, Calvello M, Cellerino A, Studer M, Cremisi F
    Stem Cell Reports 2018, 11(3), 756-69
  • Neurofibromatosis type 2 tumor suppressor protein is expressed in oligodendrocytes and regulates cell proliferation and process formation.
    Toledo* A, Grieger* E, Karram K, Morrison H, Baader SL
    PLoS One 2018, 13(5), e0196726 * equal contribution
  • Induction chemoradiotherapy versus induction chemotherapy for potentially resectable stage IIIA (N2) non-small cell lung cancer: a systematic review and meta-analysis.
    Tong S, Qin Z, Wan M, Zhang L, Cui Y, Yao Y
    J Thorac Dis 2018, 10(4), 2428-36
  • NUFIP1 is a ribosome receptor for starvation-induced ribophagy.
    Wyant* GA, Abu-Remaileh* M, Frenkel EM, Laqtom NN, Dharamdasani V, Lewis CA, Chan SH, Heinze I, Ori** A, Sabatini** DM
    Science 2018, 360(6390), 751-8 * equal contribution, ** co-corresponding authors
  • Influence of sphingosine-1-phosphate signaling on HCMV replication in human embryonal lung fibroblasts.
    Zilch A, Rien C, Weigel C, Huskobla S, Glück B, Spengler K, Sauerbrei A, Heller R, Gräler M, Henke A
    Med Microbiol Immunol 2018, 207(3-4), 227-42

Publications 2017:

  • Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo.
    Annamalai K, Liberta F, Vielberg MT, Close W, Lilie H, Gührs KH, Schierhorn A, Koehler R, Schmidt A, Haupt C, Hegenbart U, Schönland S, Schmidt M, Groll M, Fändrich M
    Angew Chem Int Ed Engl 2017, 56(26), 7510-4
  • Mutations in NOTCH1 PEST domain orchestrate CCL19-driven homing of chronic lymphocytic leukemia cells by modulating the tumor suppressor gene DUSP22.
    Arruga F, Gizdic B, Bologna C, Cignetto S, Buonincontri R, Serra S, Vaisitti T, Gizzi K, Vitale N, Garaffo G, Mereu E, Diop F, Neri F, Incarnato D, Coscia M, Allan J, Piva R, Oliviero S, Furman RR, Rossi D, Gaidano G, Deaglio S
    Leukemia 2017, 31(9), 1882-93 published during change of institution
  • PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p.
    Audrito V, Serra S, Stingi A, Orso F, Gaudino F, Bologna C, Neri F, Garaffo G, Nassini R, Baroni G, Rulli E, Massi D, Oliviero S, Piva R, Taverna D, Mandalà M, Deaglio S
    Oncotarget 2017, 8(9), 15894-911 published during change of institution
  • Comparative gene-expression profiling of the large cell variant of gastrointestinal marginal-zone B-cell lymphoma.
    Barth TFE, Kraus JM, Lausser L, Flossbach L, Schulte L, Holzmann K, Kestler** HA, Möller** P
    Sci Rep 2017, 7(1), 5963 ** co-senior authors
  • Construction of a map-based reference genome sequence for barley, Hordeum vulgare L.
    Beier S, Himmelbach A, Colmsee C, Zhang XQ, Barrero RA, Zhang Q, Li L, Bayer M, Bolser D, Taudien S, Groth M, Felder M, Hastie A, Šimková H, Staňková H, Vrána J, Chan S, Muñoz-Amatriaín M, Ounit R, Wanamaker S, Schmutzer T, Aliyeva-Schnorr L, Grasso S, Tanskanen J, Sampath D, Heavens D, Cao S, Chapman B, Dai F, Han Y, Li H, Li X, Lin C, McCooke JK, Tan C, Wang S, Yin S, Zhou G, Poland JA, Bellgard MI, Houben A, Doležel J, Ayling S, Lonardi S, Langridge P, Muehlbauer GJ, Kersey P, Clark MD, Caccamo M, Schulman AH, Platzer M, Close TJ, Hansson M, Zhang G, Braumann I, Li C, Waugh R, Scholz U, Stein N, Mascher M
    Sci Data 2017, 4, 170044
  • Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly.
    Bianchi FT, Tocco C, Pallavicini G, Liu Y, Vernì F, Merigliano C, Bonaccorsi S, El-Assawy N, Priano L, Gai M, Berto GE, Chiotto AMA, Sgrò F, Caramello A, Tasca L, Ala U, Neri F, Oliviero S, Mauro A, Geley S, Gatti M, Di Cunto F
    Cell Rep 2017, 18(7), 1674-86 published during change of institution
  • Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome.
    Binder H, Hopp L, Schweiger MR, Hoffmann S, Jühling F, Kerick M, Timmermann B, Siebert S, Grimm C, Nersisyan L, Arakelyan A, Herberg M, Buske P, Loeffler-Wirth H, Rosolowski M, Engel C, Przybilla J, Peifer M, Friedrichs N, Moeslein G, Odenthal M, Hussong M, Peters S, Holzapfel S, Nattermann J, Hueneburg R, Schmiegel W, Royer-Pokora B, Aretz S, Kloth M, Kloor M, Buettner R, Galle J, Loeffler M
    J Pathol 2017
  • Repeated intra-specific divergence in lifespan and ageing of African annual fishes along an aridity gradient.
    Blažek R, Polačik M, Kačer P, Cellerino A, Řežucha R, Methling C, Tomášek O, Syslová K, Tozzini ET, Albrecht T, Vrtílek M, Reichard M
    Evolution Int J Org Evolution 2017, 71(2), 386-402
  • Toxic effects of zinc ions on kinesin - Potential molecular cause of impaired intracellular transport.
    Böhm KJ
    Toxicol Lett 2017, 268, 58-62
  • DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.
    Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li D, Li J, Zhang B, Hou Y, Laudato S, Lipka DB, Schott J, Bierhoff H, Assenov Y, Helf M, Ressnerova A, Islam MS, Lindroth AM, Haas S, Essers M, Imbusch CD, Brors B, Oehme I, Witt O, Lübbert M, Mallm JP, Rippe K, Will R, Weichenhan D, Stoecklin G, Gerhäuser C, Oakes CC, Wang T, Plass C
    Nat Genet 2017, 49(7), 1052-60 published during change of institution
  • Renal regenerative potential of different extra-cellular vesicle populations derived from bone marrow mesenchymal stromal cells.
    Bruno S, Tapparo M, Collino F, Chiabotto G, Deregibus MC, Soares Lindoso R, Neri F, Kholia S, Giunti S, Wen S, Quesenberry P, Camussi G
    TISSUE ENG PART A 2017, 23(21-22), 1262-73
  • Ordinal Prototype-Based Classifiers
    Burkovski A, Schirra LR, Schmid F, Lausser L, Kestler HA
    Data Science Series A (Online-First) 2017, 2/1(
  • What have we learned on aging from omics studies?
    Cellerino A, Ori A
    Semin Cell Dev Biol 2017, 70, 177-89
  • MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.
    Chen Y, Anastassiadis K, Kranz A, Stewart AF, Arndt K, Waskow C, Yokoyama A, Jones K, Neff T, Lee Y, Ernst P
    Cancer Cell 2017, 31(6), 755-770.e6
  • New insights into the operative network of FaEO, an enone oxidoreductase from Fragaria x ananassa Duch.
    Collu G, Farci D, Esposito F, Pintus F, Kirkpatrick J, Piano D
    Plant Mol Biol 2017, 94(1-2), 125-36
  • HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.
    Connell M, Chen H, Jiang J, Kuan CW, Fotovati A, Chu T, He Z, Lengyell TC, Li H, Kroll T, Li AM, Goldowitz D, Frappart L, Ploubidou A, Patel M, Pilarski LM, Simpson EM, Lange P, Allan DW, Maxwell CA
    Elife 2017, 6, e28672
  • Structural Studies Revealed Active Site Distortions of Human Furin by a Small Molecule Inhibitor.
    Dahms SO, Jiao GS, Than ME
    ACS Chem Biol 2017, 12(5), 1211-6
  • Architecture of the yeast Elongator complex.
    Dauden MI, Kosinski J, Kolaj-Robin O, Desfosses A, Ori A, Faux C, Hoffmann NA, Onuma OF, Breunig KD, Beck M, Sachse C, Séraphin B, Glatt S, Müller CW
    EMBO Rep 2017, 18(2), 264-79
  • Raman and Infrared Spectroscopy Distinguishing Replicative Senescent from Proliferating Primary Human Fibroblast Cells by Detecting Spectral Differences Mainly Due to Biomolecular Alterations.
    Eberhardt K, Beleites C, Marthandan S, Matthäus C, Diekmann S, Popp J
    Anal Chem 2017, 89(5), 2937-47
  • Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models.
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  • mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance.
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    Nature 2017, 541(7635), 87-91
  • Trifunctional lipid probes for comprehensive studies of single lipid species in living cells.
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  • Corrigendum: Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells.
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  • High-throughput single-base resolution mapping of RNA 2'-O-methylated residues.
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  • Stepwise characterization of non-synonymous mutations in the HSV-1 thymidine kinase gene by different functional assays.
    Kaspar M, Bohn-Wippert K, Bellstedt P, Häfner S, Görlach M, Sauerbrei A
    J Virol Methods 2017, 247, 51-7
  • Differential Effects of Vitamins A and D on the Transcriptional Landscape of Human Monocytes during Infection.
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  • Verification and characterization of an alternative low density lipoprotein receptor-related protein 1 splice variant.
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  • The anti-tumorigenic activity of A2M-A lesson from the naked mole-rat.
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  • Hacking the stem cell niche.
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    Blood 2017, 129(22), 2951-2
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    Lanver D, Tollot M, Schweizer G, Lo Presti L, Reissmann S, Ma LS, Schuster M, Tanaka S, Liang L, Ludwig N, Kahmann R
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  • The Influence of Multi-class Feature Selection on the Prediction of Diagnostic Phenotypes
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  • Spindle Misorientation of Cerebral and Cerebellar Progenitors Is a Mechanistic Cause of Megalencephaly.
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    Stem Cell Reports 2017, 9(4), 1071-80
  • The E3 ubiquitin ligase APC/C(C)(dh1) degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis.
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    Mol Syst Biol 2017, 13(12), 962 ** co-corresponding authors, highlighted in the “Principle of Systems Biology” - Cell Systems 6 - 2018
  • A chromosome conformation capture ordered sequence of the barley genome.
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  • Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity.
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  • N-Heterocyclic (4-Phenylpiperazin-1-yl)methanones Derived from Phenoxazine and Phenothiazine as Highly Potent Inhibitors of Tubulin Polymerization.
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  • Mitochondrial BAX Determines the Predisposition to Apoptosis in Human AML.
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  • Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells.
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  • MicroRNA miR-29 controls a compensatory response to limit neuronal iron accumulation during adult life and aging.
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    Leukemia 2017, 31(4), 889-95
  • Macrophage's little helper: vitamin A directs alternatively activated monocyte-derived macrophages to tissue-resident macrophages.
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    Cell Mol Immunol 2017, 14(10), 805-8
  • The protein-tyrosine phosphatase DEP-1 promotes migration and phagocytic activity of microglial cells in part through negative regulation of fyn tyrosine kinase.
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    Glia 2017, 65(2), 416-28
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    Mol Cell Neurosci 2017, 78, 1-8
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    J Cancer Res Clin Oncol 2017, 143(5), 807-20
  • Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells.
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  • ViSiBooL - visualization and simulation of Boolean networks with temporal constraints.
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    Bioinformatics 2017, 33(4), 601-4 ** co-senior authors
  • Stability of Signaling Pathways during Aging-A Boolean Network Approach.
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    Biology (Basel) 2017, 6(4)
  • An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
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    Diabetes 2017, 66(11), 2888-902
  • TRE5-A retrotransposition profiling reveals putative RNA polymerase III transcription complex binding sites on the Dictyostelium extrachromosomal rDNA element.
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    PLoS One 2017, 12(4), e0175729
  • Candidate Brocadiales dominates C, N and S cycling in anoxic groundwater of a pristine limestone-fracture aquifer.
    Starke R, Müller M, Gaspar M, Marz M, Küsel K, Totsche KU, von Bergen M, Jehmlich N
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  • Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development.
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  • Switch-like behavior enables Wnt11 concentration specific response during dorso-ventral axis formation in Xenopus laevis.
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    J Theor Biol 2017, 429, 82-94 ** co-senior authors
  • Cdc45-induced loading of human RPA onto single-stranded DNA.
    Szambowska A, Tessmer I, Prus P, Schlott B, Pospiech H, Grosse F
    Nucleic Acids Res 2017, 45(6), 3217-30
  • Lysine Acetylation and Deacetylation in Brain Development and Neuropathies.
    Tapias A, Wang ZQ
    Genomics Proteomics Bioinformatics 2017, 15(1), 19-36
  • Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis.
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  • RHEB1 insufficiency in aged male mice is associated with stress-induced seizures.
    Tian Q, Gromov P, Clement JH, Wang Y, Riemann M, Weih F, Sun XX, Dai MS, Fedorov LM
    Geroscience 2017, 39(5-6), 557-70
  • Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation.
    Tsitsipatis D, Jayavelu AK, Müller JP, Bauer R, Schmidt-Arras D, Mahboobi S, Schnöder TM, Heidel F, Böhmer FD
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  • Keeping it complicated: Mitochondrial genome plasticity across diplonemids.
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    Sci Rep 2017, 7(1), 14166
  • The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.
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  • NMR spectroscopic studies of a TAT-derived model peptide in imidazolium-based ILs: influence on chemical shifts and the cis/trans equilibrium state.
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    Phys Chem Chem Phys 2017, 19(35), 24115-25
  • Synthesis and Evaluation of Amyloid β Derived and Amyloid β Independent Enhancers of the Peroxidase-like Activity of Heme.
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  • A Stably Protonated Adenine Nucleotide with a Highly Shifted pKa Value Stabilizes the Tertiary Structure of a GTP-Binding RNA Aptamer.
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  • Nucleosome Positioning Assay
    Zhao Z, Bierhoff H
    Bio-protocol 2017, 7(10), e2285

Publications 2016:

  • Differential sensitivity of lipegfilgrastim and pegfilgrastim to neutrophil elastase correlates with differences in clinical pharmacokinetic profile.
    Abdolzade-Bavil A, von Kerczek A, Cooksey BA, Kaufman T, Krasney PA, Pukac L, Görlach M, Lammerich A, Scheckermann C, Allgaier H, Shen WD, Liu PM
    J Clin Pharmacol 2016, 56(2), 186-94
  • Polymorphism of Amyloid Fibrils In Vivo.
    Annamalai K, Gührs KH, Koehler R, Schmidt M, Michel H, Loos C, Gaffney PM, Sigurdson CJ, Hegenbart U, Schönland S, Fändrich M
    Angew Chem Int Ed Engl 2016, 55(15), 4822-5
  • Impact of FLT3-ITD location on sensitivity to TKI-therapy in vitro and in vivo.
    Arreba-Tutusaus P, Mack TS, Bullinger L, Schnöder TM, Polanetzki A, Weinert S, Ballaschk A, Wang Z, Deshpande AJ, Armstrong SA, Döhner K, Fischer T, Heidel FH
    Leukemia 2016, 30(5), 1220-5
  • Multiplex sequencing of bacterial artificial chromosomes for assembling complex plant genomes.
    Beier S, Himmelbach A, Schmutzer T, Felder M, Taudien S, Mayer KFX, Platzer M, Stein N, Scholz U, Mascher M
    Plant Biotechnol J 2016, 14(7), 1511-22
  • Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer.
    Bernhart SH, Kretzmer H, Holdt LM, Jühling F, Ammerpohl O, Bergmann AK, Northoff BH, Doose G, Siebert R, Stadler PF, Hoffmann S
    Sci Rep 2016, 6, 37393
  • Blood stem cells: from beginning to end.
    Bigas A, Waskow C
    Development 2016, 143(19), 3429-33
  • From the bush to the bench: the annual Nothobranchius fishes as a new model system in biology.
    Cellerino A, Valenzano DR, Reichard M
    Biol Rev Camb Philos Soc 2016, 91(2), 511-33
  • Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing.
    Chandel NS, Jasper H, Ho TT, Passegué E
    Nat Cell Biol 2016, 18(8), 823-32
  • Discovering miRNA regulatory networks in Holt-Oram Syndrome using a Zebrafish model
    D'Aurizio R, Russo F, Chiavacci E, Baumgart M, Groth M, D'Onofrio M, Arisi I, Rainaldi G, Pitto L, Pellegrini M
    Front. Bioeng. Biotechnol. 2016, 4, Article 60
  • Boolean modeling identifies greatwall/MASTL as an important regulator in the AURKA network of neuroblastoma.
    Dahlhaus M, Burkovski A, Hertwig F, Mussel C, Volland R, Fischer M, Debatin KM, Kestler** HA, Beltinger** C
    Cancer Lett 2016, 371(1), 79-89 ** co-corresponding authors
  • The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.
    Dahms SO, Creemers JWM, Schaub Y, Bourenkov GP, Zögg T, Brandstetter H, Than ME
    Sci Rep 2016, 6, 34303.doi:10.1038/srep303
  • Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.
    Dahms* SO, Arciniega* M, Steinmetzer T, Huber** R, Than** ME
    Proc Natl Acad Sci U S A 2016, 113(40), 11196-201 * equal contribution, ** co-corresponding authors
  • The role of hypothalamic NF-κB signaling in the response of the HPT-axis to acute inflammation in female mice.
    de Vries EM, Nagel S, Haenold R, Sundaram SM, Pfrieger FW, Fliers E, Heuer H, Boelen A
    Endocrinology 2016, 157(7), 2947-56
  • Analysis of cultivable microbiota and diet intake pattern of the long-lived naked mole-rat.
    Debebe T, Holtze S, Morhart M, Hildebrandt TB, Rodewald S, Huse K, Platzer M, Wyohannes D, Yirga S, Lemma A, Thieme R, König B, Birkenmeier G
    Gut Pathog 2016, 8, 25
  • Ethyl Pyruvate: An Anti-Microbial Agent that Selectively Targets Pathobionts and Biofilms.
    Debebe T, Krüger M, Huse K, Kacza J, Mühlberg K, König B, Birkenmeier G
    PLoS One 2016, 11(9), e0162919
  • Sexual Dimorphism: How Female Cells Win the Race.
    Deng H, Jasper H
    Curr Biol 2016, 26(5), R212-5
  • Reply to Hart et al.: MINCR and MYC: More than expression correlation.
    Doose G, Hoffmann S, Iaccarino I
    Proc Natl Acad Sci U S A 2016, 113(5), E498
  • What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand Specificity of the Neomycin-Sensing Riboswitch.
    Duchardt-Ferner E, Gottstein-Schmidtke SR, Weigand JE, Ohlenschläger O, Wurm JP, Hammann C, Suess B, Wöhnert J
    Angew Chem Int Ed Engl 2016, 55(4), 1527-30
  • Expression and function of ABC-transporter protein ABCB1 correlates with inhibitory capacity of Ruxolitinib in vitro and in vivo.
    Ebert C, Perner F, Wolleschak D, Schnöder TM, Fischer T, Heidel FH
    Haematologica 2016, 101(3), e81-5
  • DNA Damage as a Critical Factor of Stem Cell Aging and Organ Homeostasis
    Espada L, Ermolaeva MA
    Curr Stem Cell Rep 2016, 2, 290-8
  • Multifocal Nerve Lesions and LZTR1 Germline Mutations in Segmental Schwannomatosis.
    Farschtschi S, Mautner VF, Pham M, Nguyen R, Kehrer-Sawatzki H, Hutter S, Friedrich RE, Schulz A, Morrison H, Jones DTW, Bendszus M, Bäumer P
    Ann Neurol 2016, 80(4), 625-8
  • Automated structure modeling of large protein assemblies using crosslinks as distance restraints.
    Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M, Simon B, Bouvier G, Batista PR, Müller CW, Beck M, Nilges M
    Nat Methods 2016, 13(6), 515-20 published during change of institution
  • The tumour suppressor CYLD regulates the p53 DNA damage response.
    Fernández-Majada V, Welz PS, Ermolaeva MA, Schell M, Adam A, Dietlein F, Komander D, Büttner R, Thomas RK, Schumacher B, Pasparakis M
    Nat Commun 2016, 7, 12508 published during change of institution
  • S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.
    Foertsch F, Szambowska A, Weise A, Zielinski A, Schlott B, Kraft F, Mrasek K, Borgmann K, Pospiech** H, Grosse F, Melle** C
    Cell Cycle 2016, 15(20), 2766-79 ** co-corresponding authors
  • Prediction of conserved long-range RNA-RNA interactions in full viral genomes.
    Fricke M, Marz M
    Bioinformatics 2016, 32(19), 2928-35
  • High Copy Numbers of Beta-Defensin Cluster on 8p23.1 Confer Genetic Susceptibility and Modulate the Physical Course of Hidradenitis Suppurativa/Acne Inversa.
    Giamarellos-Bourboulis* EJ, Platzer* M, Karagiannidis* I, Kanni T, Nikolakis G, Ulrich J, Bellutti M, Gollnick H, Bauer M, Zouboulis CC, Huse K
    J Invest Dermatol 2016, 136(8), 1592-8 * equal contribution
  • You Are What You Eat: Linking High-Fat Diet to Stem Cell Dysfunction and Tumorigenesis.
    Haller S, Jasper H
    Cell Stem Cell 2016, 18(5), 564-6
  • DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression.
    Hampp S, Kiessling T, Buechle K, Mansilla SF, Thomale J, Rall M, Ahn J, Pospiech H, Gottifredi V, Wiesmüller L
    Proc Natl Acad Sci U S A 2016, 113(30), E4311-9
  • Gene Dosage Reductions of Trf1 and/or Tin2 Induce Telomere DNA Damage and Lymphoma Formation in Aging Mice.
    Hartmann K, Illing A, Leithäuser F, Baisantry A, Quintanilla-Fend L, Rudolph KL
    Leukemia 2016, 30(3), 749-53
  • Feedback activation of neurofibromin terminates growth factor-induced Ras activation.
    Hennig A, Markwart R, Wolff K, Schubert K, Cui Y, Prior IA, Esparza-Franco MA, Ladds G, Rubio I
    Cell Commun Signal 2016, 14(1), 5
  • Age-Dependent Changes of Monocarboxylate Transporter 8 Availability in the Postnatal Murine Retina.
    Henning Y, Szafranski K
    Front Cell Neurosci 2016, 10, 205
  • Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis.
    Hezaveh K, Kloetgen A, Bernhart SH, Mahapatra KD, Lenze D, Richter J, Haake A, Bergmann AK, Brors B, Burkhardt B, Claviez A, Drexler HG, Eils R, Haas S, Hoffmann S, Karsch D, Klapper W, Kleinheinz K, Korbel J, Kretzmer H, Kreuz M, Küppers R, Lawerenz C, Leich E, Loeffler M, Mantovani-Loeffler L, López C, McHardy AC, Möller P, Rohde M, Rosenstiel P, Rosenwald A, Schilhabel M, Schlesner M, Scholz I, Stadler PF, Stilgenbauer S, Sungalee S, Szczepanowski M, Trümper L, Weniger MA, Siebert R, Borkhardt A, Hummel M, Hoell JI, ICGC MMML-Seq Project
    Haematologica 2016, 101(11), 1380-9
  • Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.
    Hoa NN, Shimizu T, Zhou ZW, Wang ZQ, Deshpande RA, Paull TT, Akter S, Tsuda M, Furuta R, Tsusui K, Takeda S, Sasanuma H
    Mol Cell 2016, 64(3), 580-92
  • Whole-Genome Sequence of Chlamydia gallinacea Type Strain 08-1274/3.
    Hölzer M, Laroucau K, Creasy HH, Ott S, Vorimore F, Bavoil PM, Marz M, Sachse K
    Genome Announc 2016, 4(4), pii: e00708-16
  • Leukemogenic potency of the novel FLT3-N676K mutant.
    Huang K, Yang M, Pan Z, Heidel FH, Scherr M, Eder M, Fischer T, Büsche G, Welte K, von Neuhoff N, Ganser A, Li Z
    Ann Hematol 2016, 95(5), 783-91
  • Wnt/β-catenin signaling via Axin2 is required for myogenesis and, together with YAP/Taz and Tead1, active in IIa/IIx muscle fibers.
    Huraskin D, Eiber N, Reichel M, Zidek LM, Kravic B, Bernkopf D, von Maltzahn J, Behrens J, Hashemolhosseini S
    Development 2016, 143(17), 3128-42
  • Control of apoptosis by Drosophila DCAF12.
    Hwangbo DS, Biteau B, Rath S, Kim J, Jasper H
    Dev Biol 2016, 413(1), 50-9
  • RNA structure framework: automated transcriptome-wide reconstruction of RNA secondary structures from high-throughput structure probing data.
    Incarnato D, Neri F, Anselmi F, Oliviero S
    Bioinformatics 2016, 32(3), 459-61 published during change of institution
  • Human DNA polymerase α interacts with mismatch repair proteins MSH2 and MSH6.
    Itkonen HM, Kantelinen J, Vaara M, Parkkinen S, Schlott B, Grosse F, Nyström M, Syväoja JE, Pospiech H
    FEBS Lett 2016, 590(23), 4233-41
  • Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation.
    Jaenicke* LA, von Eyss* B, Carstensen A, Wolf E, Xu W, Greifenberg AK, Geyer M, Eilers M, Popov N
    Mol Cell 2016, 61(1), 54-67 * equal contribution
  • NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells.
    Jayavelu AK, Müller JP, Bauer R, Böhmer SA, Lässig J, Cerny-Reiterer S, Sperr WR, Valent P, Maurer B, Moriggl R, Schröder K, Shah AM, Fischer M, Scholl S, Barth J, Oellerich T, Berg T, Serve H, Frey S, Fischer T, Heidel FH, Böhmer FD
    Leukemia 2016, 30(2), 473-83
  • Characteristics and treatment of polycythemia vera patients in clinical practice: a multicenter chart review on 1476 individuals in Germany.
    Jentsch-Ullrich K, Eberhardt J, Zeremski V, Koehler M, Wolleschak D, Heidel FH
    J Cancer Res Clin Oncol 2016 (epub ahead of print)
  • A homolog of Blade-On-Petiole 1 and 2 (BOP1/2) controls internode length and homeotic changes of the barley inflorescence.
    Jost M, Taketa S, Mascher M, Himmelbach A, Yuo T, Shahinnia F, Rutten T, Druka A, Schmutzer T, Steuernagel B, Beier S, Taudien S, Scholz U, Morgante M, Waugh R, Stein N
    Plant Physiol 2016, 171(2), 1113-27
  • metilene: fast and sensitive calling of differentially methylated regions from bisulfite sequencing data.
    Jühling F, Kretzmer H, Bernhart SH, Otto C, Stadler PF, Hoffmann S
    Genome Res 2016, 26(2), 256-62
  • PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways.
    Kaistha BP, Lorenz H, Schmidt H, Sipos B, Pawlak M, Gierke B, Kreider R, Lankat-Buttgereit B, Sauer M, Fiedler L, Krattenmacher A, Geisel B, Kraus JM, Frese KK, Kelkenberg S, Giese NA, Kestler HA, Gress TM, Buchholz M
    Cancer Res 2016, 76(96-107)
  • Molecular specification of germ layers in vertebrate embryos.
    Kiecker C, Bates T, Bell E
    Cell Mol Life Sci 2016, 73(5), 923-47
  • Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry.
    Kiosze-Becker K, Ori A, Gerovac M, Heuer A, Nürenberg-Goloub E, Rashid UJ, Becker T, Beckmann R, Beck M, Tampé R
    Nat Commun 2016, 7, 13248
  • Streptococci Engage TLR13 on Myeloid Cells in a Site-Specific Fashion.
    Kolter J, Feuerstein R, Spoeri E, Gharun K, Elling R, Trieu-Cuot P, Goldmann T, Waskow C, Chen ZJ, Kirschning CJ, Deshmukh SD, Henneke P
    J Immunol 2016, 196(6), 2733-41
  • Developmental endothelial locus-1 modulates platelet-monocyte interactions and instant blood-mediated inflammatory reaction in islet transplantation.
    Kourtzelis I, Kotlabova K, Lim JH, Mitroulis I, Ferreira A, Chen LS, Gercken B, Steffen A, Kemter E, Klotzsche-von Ameln A, Waskow C, Hosur K, Chatzigeorgiou A, Ludwig B, Wolf E, Hajishengallis G, Chavakis T
    Thromb Haemost 2016, 115(4), 781-8
  • Phagocytosis of bone marrow derived macrophages is controlled by phosphoinositide 3-kinase γ.
    Kresinsky A, Schneble N, Schmidt C, Frister A, Bauer R, Wetzker R, Müller JP
    Immunol Lett 2016, 180, 9-16
  • Analysis of an echovirus 18 outbreak in Thuringia, Germany: insights into the molecular epidemiology and evolution of several enterovirus species B members.
    Krumbholz A, Egerer R, Braun H, Schmidtke M, Rimek D, Kroh C, Hennig B, Groth M, Sauerbrei A, Zell R
    Med Microbiol Immunol 2016, 205(5), 471-83
  • Solvent Removal Induces a Reversible β-to-α Switch in Oligomeric Aβ Peptide.
    Kumar ST, Leppert J, Bellstedt P, Wiedemann C, Fändrich** M, Görlach** M
    J Mol Biol 2016, 428(2 Pt A), 268-73 ** co-corresponding authors
  • Abolishing Aging? Ethical implications of biological research on aging. Gemeinsames Seminar des Fritz Lipmann Institutes und des Ethikzentrums der Friedrich-Schiller-Universität Jena
    Kunzmann P, Briest W, Ehni HJ
    In: Diskurs Biogerontologie, Fachwissenschaftliche Einführung und Leitfaden für Lehrende (edited by Spindler M, Dietrich J, Ehni HJ) 2016, 285-287, Springer VS, Wiesbaden
  • Gastrointestinal stem cells in health and disease: from flies to humans.
    Li H, Jasper H
    Dis Model Mech 2016, 9(5), 487-99
  • Preventing Age-Related Decline of Gut Compartmentalization Limits Microbiota Dysbiosis and Extends Lifespan.
    Li H, Qi Y, Jasper H
    CELL HOST MICROBE 2016, 19(2), 240-53
  • DNA Damage Response in Hematopoietic Stem Cell Ageing.
    Li T, Zhou ZW, Ju Z, Wang ZQ
    Genomics Proteomics Bioinformatics 2016, 14(3), 147-54
  • Telomere shortening leads to earlier age of onset in ALS mice.
    Linkus B, Wiesner D, Meßner M, Karabatsiakis A, Scheffold A, Rudolph KL, Thal DR, Weishaupt JH, Ludolph AC, Danzer KM
    Aging (Albany NY) 2016, 8(2), 382-93
  • Different promoter affinities account for specificity in MYC-dependent gene regulation.
    Lorenzin F, Benary U, Baluapuri A, Walz S, Jung LA, von Eyss B, Kisker C, Wolf J, Eilers M, Wolf E
    Elife 2016, 5. pii: e15161, doi: 10.7554/eLife.15161.
  • Transcriptomic profiling of Alexandrium fundyense during physical interaction with or exposure to chemical signals from the parasite Amoebophrya.
    Lu Y, Wohlrab S, Groth M, Glöckner G, Guillou L, John U
    Mol Ecol 2016, 25(6), 1294-307
  • Intestinal IRE1 Is Required for Increased Triglyceride Metabolism and Longer Lifespan under Dietary Restriction.
    Luis NM, Wang L, Ortega M, Deng H, Katewa SD, Li PWL, Karpac J, Jasper** H, Kapahi** P
    Cell Rep 2016, 17(5), 1207-16 ** co-corresponding authors
  • The distribution of α-kleisin during meiosis in the holocentromeric plant Luzula elegans.
    Ma W, Schubert V, Martis MM, Hause G, Liu Z, Shen Y, Conrad U, Shi W, Scholz U, Taudien S, Cheng Z, Houben A
    Chromosome Res 2016 (epub ahead of print)
  • Coronavirus cis-Acting RNA Elements.
    Madhugiri R, Fricke M, Marz M, Ziebuhr J
    In: Advances in Virus Research (edited by John Ziebuhr) 2016, 96, 127-163, Elsevier Inc. Academic
  • The long intergenic non-coding RNA CCR492 functions as a let-7 competitive endogenous RNA to regulate c-Myc expression.
    Maldotti M, Incarnato D, Neri F, Krepelova A, Rapelli S, Anselmi F, Parlato C, Basile G, Dettori D, Calogero R, Oliviero S
    Biochim. Biophys. Acta-Gene Regul. Mech. 2016, 1859(10), 1322-32 published during change of institution
  • Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq.
    Marthandan S, Baumgart M, Priebe S, Groth M, Schaer J, Kaether C, Guthke R, Cellerino A, Platzer M, Diekmann S, Hemmerich P
    PLoS One 2016, 11(5), e0154531
  • Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence.
    Marthandan S, Menzel U, Priebe S, Groth M, Guthke R, Platzer M, Hemmerich P, Kaether C, Diekmann S
    Biol Res 2016, 49(1), 34
  • Olfactory phenotypic expression unveils human aging.
    Mazzatenta A, Cellerino A, Origlia N, Barloscio D, Sartucci F, Di Giulio C, Domenici L
    Oncotarget 2016, 7(15), 19193-200
  • Analyses of fugu hoxa2 genes provide evidence for subfunctionalization of neural crest cell and rhombomere cis-regulatory modules during vertebrate evolution.
    McEllin JA, Alexander TB, Tümpel S, Wiedemann LM, Krumlauf R
    Dev Biol 2016, 409(2), 530-42
  • Multilineage readout after HSC expansion - erythrocytes matter.
    Mende N, Rahmig S, Waskow C
    Cell Cycle 2016, 15(8), 1032-3
  • A standardized production pipeline for high profile targets from Mycobacterium tuberculosis.
    Milewski MC, Broger T, Kirkpatrick J, Filomena A, Komadina D, Schneiderhan-Marra N, Wilmanns M, Parret AHA
    Proteom Clin Appl 2016, 10(9-10), 1049-57
  • BiTrinA - multiscale binarization and trinarization with quality analysis.
    Mϋssel C, Schmid F, Blätte TJ, Hopfensitz M, Lausser** L, Kestler** HA
    Bioinformatics 2016, 32(3), 465-8 ** co-senior authors
  • Methylation-assisted bisulfite sequencing to simultaneously map 5fC and 5caC on a genome-wide scale for DNA demethylation analysis.
    Neri F, Incarnato D, Krepelova A, Parlato C, Oliviero S
    Nat Protoc 2016, 11(7), 1191-205 published during change of institution
  • Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients.
    Obermeier K, Sachsenweger J, Friedl TWP, Pospiech H, Winqvist R, Wiesmüller L
    Oncogene 2016, 35(29), 3796-806
  • Spatiotemporal variation of mammalian protein complex stoichiometries.
    Ori A, Iskar M, Buczak K, Kastritis P, Parca L, Andrés-Pons A, Singer S, Bork P, Beck M
    Genome Biol 2016, 17(1), 47 featured in Research Highlights by Michael P. Washburn: There is no human interactome. Genome Biology 2016 17:48
  • Growth factor and co-receptor release by structural regulation of substrate metalloprotease accessibility.
    Parra* LM, Hartmann* M, Schubach S, Ma J, Herrlich** P, Herrlich** A
    Sci Rep 2016, 6, 37464 * equal contribution, ** co-senior authors
  • Comparative genomics to explore phylogenetic relationship, cryptic sexual potential and host specificity of Rhynchosporium species on grasses.
    Penselin D, Münsterkötter M, Kirsten S, Felder M, Taudien S, Platzer M, Ashelford K, Paskiewicz KH, Harrison RJ, Hughes DJ, Wolf T, Shelest E, Graap J, Hoffmann J, Wenzel C, Wöltje N, King KM, Fitt BDL, Güldener U, Avrova A, Knogge W
    BMC Genomics 2016, 17(1), 953
  • Immunofluorescence Staining of Wt1 on Sections of Zebrafish Embryos and Larvae.
    Perner B, Englert C
    In: The Wilms' Tumor (WT1) Gene, Methods and Protocols (edited by Nicholas Hastie), Methods in Molecular Biology 2016, 1467, 129-32, Springer New York, New Y
  • Kinomics Screening Identifies Aberrant Phosphorylation of CDC25C in FLT3-ITD-positive AML.
    Perner F, Schnöder TM, Fischer T, Heidel FH
    Anticancer Res 2016, 36(12), 6249-58
  • Specificity of JAK-kinase inhibition determines impact on human and murine T-cell function.
    Perner F, Schnöder TM, Ranjan S, Wolleschak D, Ebert C, Pils MC, Frey S, Polanetzki A, Fahldieck C, Schönborn U, Schraven B, Isermann B, Fischer T, Heidel FH
    Leukemia 2016, 30(4), 991-5
  • Genotyping of herpes simplex virus type 1 by whole-genome sequencing.
    Pfaff F, Groth M, Sauerbrei A, Zell R
    J Gen Virol 2016, 97(10), 2732-41
  • Nothobranchius furzeri: A Model for Aging Research and More.
    Platzer M, Englert C
    Trends Genet 2016, 32(9), 543-52
  • The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export.
    Port SA, Mendes A, Valkova C, Spillner C, Fahrenkrog B, Kaether C, Kehlenbach RH
    J Biol Chem 2016, 291(44), 23068-83
  • Assembly of the Cdc45-Mcm2-7-GINS Complex, the Replication Helicase
    Pospiech H, Szambowska A
    In: The Initiation of DNA Replication in Eukaryot (edited by Daniel Kaplan) 2016, 393-409, Springer International
  • Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice.
    Rahmig S, Kronstein-Wiedemann R, Fohgrub J, Kronstein N, Nevmerzhitskaya A, Bornhäuser M, Gassmann M, Platz A, Ordemann R, Tonn T, Waskow C
    Stem Cell Reports 2016, 7(4), 591-601
  • Alternative splicing of SMPD1 coding for acid sphingomyelinase in major depression.
    Rhein C, Reichel M, Kramer M, Rotter A, Lenz B, Mühle C, Gulbins E, Kornhuber J
    J Affect Disord 2016 (epub ahead of print)
  • p21 shapes cancer evolution.
    Romanov VS, Rudolph KL
    Nat Cell Biol 2016, 18(7), 722-4
  • Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death.
    Salah FS, Ebbinghaus M, Muley VY, Zhou Z, Al-Saadi KRD, Pacyna-Gengelbach M, O'Sullivan GA, Betz H, König R, Wang ZQ, Bräuer R, Petersen I
    Cell Death Dis 2016, 7, e2205
  • MHC-dependent mate choice is linked to a trace-amine-associated receptor gene in a mammal.
    Santos PSC, Courtiol A, Heidel AJ, Höner OP, Heckmann I, Nagy M, Mayer F, Platzer M, Voigt CC, Sommer S
    Sci Rep 2016, 6, 38490
  • Cool-temperature-mediated activation of phospholipase C-γ2 in the human hereditary disease PLAID.
    Schade A, Walliser C, Wist M, Haas J, Vatter P, Kraus JM, Filingeri D, Havenith G, Kestler HA, Milner JD, Gierschik P
    Cell Signal 2016, 28(9), 1237-51
  • Leukemic mastopathy.
    Schalk E, Heidel FH
    Int J Hematol 2016, 103(4), 357-8
  • The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
    Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, Lundberg E, Perez F, Beck M, Bork P, Pepperkok R
    J Cell Biol 2016, 215(4), 543-58 published during change of institution
  • Anti-amyloid compounds protect from silica nanoparticle-induced neurotoxicity in the nematode C. elegans.
    Scharf A, Gührs KH, von Mikecz A
    Nanotoxicology 2016, 10(4), 426-35
  • Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model.
    Scheffold A, Holtman IR, Dieni S, Brouwer N, Katz SF, Jebaraj BMC, Kahle PJ, Hengerer B, Lechel A, Stilgenbauer S, Boddeke EWGM, Eggen BJL, Rudolph KL, Biber K
    Acta Neuropathol Commun 2016, 4(1), 87
  • Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality.
    Scherag A, Schöneweck F, Kesselmeier M, Taudien S, Platzer M, Felder M, Sponholz C, Rautanen A, Hill AVS, Hinds CJ, Hossain H, Suttorp N, Kurzai O, Slevogt H, Giamarellos-Bourboulis EJ, Armaganidis A, Trips E, Scholz M, Brunkhorst FM
    EBioMedicine 2016, 12, 239-46
  • GiANT: Gene set uncertainty in enrichment analysis.
    Schmid F, Schmid M, Müssel C, Sträng JE, Buske C, Bullinger L, Kraus JM, Kestler HA
    Bioinformatics 2016, 32(12), 1891-4
  • Phosphoinositide 3-Kinase γ Restrains Neurotoxic Effects of Microglia After Focal Brain Ischemia.
    Schmidt C, Frahm C, Schneble N, Müller JP, Brodhun M, Franco I, Witte OW, Hirsch E, Wetzker R, Bauer R
    Mol Neurobiol 2016, 53(8), 5468-79
  • Lipedema – lack of evidence for the involvement of tyrosine kinases.
    Schneble N, Wetzker R, Wollina U
    J Biol Regul Homeost Agents 2016, 30(1), 161-3
  • The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis.
    Schoedel KB, Morcos MNF, Zerjatke T, Roeder I, Grinenko T, Voehringer D, Göthert JR, Waskow C, Roers A, Gerbaulet A
    Blood 2016, 128(19), 2285-96
  • An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation.
    Schur FKM, Obr M, Hagen WJH, Wan W, Jakobi AJ, Kirkpatrick JM, Sachse C, Kräusslich HG, Briggs JAG
    Science 2016, 353(6298), 506-8 published during change of institution
  • Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis.
    Seidel P, Remus M, Delacher M, Grigaravicius P, Reuss DE, Frappart L, von Deimling A, Feueuer M, Abdollahi A, Frappart PO
    Oncotarget 2016, 7(17), 23006-18
  • BCL3 Reduces the Sterile Inflammatory Response in Pancreatic and Biliary Tissues.
    Song L, Wörmann S, Ai J, Neuhöfer P, Lesina M, Diakopoulos KN, Ruess D, Treiber M, Witt H, Bassermann F, Halangk W, Steiner JM, Esposito I, Rosendahl J, Schmid RM, Riemann M, Algül H
    Gastroenterology 2016, 150(2), 499-512
  • Polymorphisms of cystathionine beta-synthase gene are associated with susceptibility to sepsis.
    Sponholz C, Kramer M, Schöneweck F, Menzel U, Inanloo Rahatloo K, Giamarellos-Bourboulis EJ, Papavassileiou V, Lymberopoulou K, Pavlaki M, Koutelidakis I, Perdios I, Scherag A, Bauer M, Platzer M, Huse K
    Eur J Hum Genet 2016, 24(7), 1041-8
  • Genetic Factors of the Disease Course After Sepsis: Rare Deleterious Variants Are Predictive.
    Taudien* S, Lausser* L, Giamarellos-Bourboulis EJ, Sponholz C, Schöneweck F, Felder M, Schirra LR, Schmid F, Gogos C, Groth S, Petersen BS, Franke A, Lieb W, Huse K, Zipfel PF, Kurzai O, Moepps B, Gierschik P, Bauer M, Scherag A, Kestler** HA, Platzer** M
    EBioMedicine 2016, 12, 227-38 * equal contribution, ** co-senior authors
  • PARP activation promotes nuclear AID accumulation in lymphoma cells.
    Tepper S, Jeschke J, Böttcher K, Schmidt A, Davari K, Müller P, Kremmer E, Hemmerich P, Pfeil I, Jungnickel B
    Oncotarget 2016, 7(11), 13197-208
  • Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6.
    Uras IZ, Walter GJ, Scheicher R, Bellutti F, Prchal-Murphy M, Tigan AS, Valent P, Heidel FH, Kubicek S, Scholl C, Fröhling S, Sexl V
    Blood 2016, 127(23), 2890-902
  • Stress promotes Arabidopsis - Piriformospora indica interaction.
    Vahabi K, Dorcheh SK, Monajembashi S, Westermann M, Reichelt M, Falkenberg D, Hemmerich P, Sherameti I, Oelmüller R
    Plant Signal Behav 2016, 11(5), e1136763
  • NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions.
    Vlantis K, Wullaert A, Polykratis A, Kondylis V, Dannappel M, Schwarzer R, Welz P, Corona T, Walczak H, Weih F, Klein U, Kelliher M, Pasparakis M
    Immunity 2016, 44(3), 553-67
  • TraqBio - Flexible Progress Tracking for Core Unit Projects.
    Völkel G, Wiese S, Holzmann K, Kraus JM, Schneider F, Görlach M, Kestler HA
    PLoS One 2016, 11(9), e0162857
  • Characterization of SKAP/Kinastrin isoforms - The N-terminus defines tissue specificity and Pontin binding.
    Vranesic AC, Reiche J, Hoischen C, Wohlmann A, Bratsch J, Friedrich K, Günes B, Cappallo-Obermann H, Kirchhoff C, Diekmann S, Günes C, Huber O
    Hum Mol Genet 2016, 25(13), 2838-52
  • SIRT6 Controls Hematopoietic Stem Cell Homeostasis through Epigenetic Regulation of Wnt Signaling.
    Wang H, Diao D, Shi Z, Zhu X, Gao Y, Gao S, Liu X, Wu Y, Rudolph KL, Liu G, Li T, Ju Z
    Cell Stem Cell 2016, 18(4), 495-507
  • A Set of Efficient nD NMR Protocols for Resonance Assignments of Intrinsically Disordered Proteins.
    Wiedemann C, Bellstedt P, Häfner S, Herbst C, Bordusa F, Görlach M, Ohlenschläger O, Ramachandran R
    Chemphyschem 2016, 17(13), 1961-8
  • Analysis of Large and Complex Data
    Wilhelm AFX, Kestler HA (eds)
    Book series: Studies in Classification, Data Analysis, and Knowledge Organization 2016, Springer International Publishin
  • Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC).
    Winkler J, Roessler S, Sticht C, DiGuilio AL, Drucker E, Holzer K, Eiteneuer E, Herpel E, Breuhahn K, Gretz N, Schirmacher P, Ori A, Singer S
    Oncotarget 2016, 7(16), 22883-92
  • Finding approximate gene clusters with Gecko 3.
    Winter S, Jahn K, Wehner S, Kuchenbecker L, Marz M, Stoye J, Böcker S
    Nucleic Acids Res 2016, 44(20), 9600-10
  • Chronic myelogenous leukemia evolving after treatment of multiple myeloma.
    Wolleschak D, Heidel FH
    Blood 2016, 128(1), 146
  • Attenuated LKB1-SIK1 signaling promotes epithelial-mesenchymal transition and radioresistance of non-small cell lung cancer cells.
    Yao YH, Cui Y, Qiu XN, Zhang LZ, Zhang W, Li H, Yu JM
    Chin J Cancer 2016, 35(1), 50
  • Inhibition of cargo export at ER-exit sites and the trans-Golgi network by the secretion inhibitor FLI-06.
    Yonemura Y, Li X, Müller K, Krämer A, Atigbire P, Mentrup T, Feuerhake T, Kroll T, Shomron O, Nohl R, Arndt HD, Hoischen C, Hemmerich P, Hirschberg K, Kaether C
    J Cell Sci 2016, 129(20), 3868-77
  • Age-Dependent Changes of Monocarboxylate Transporter 8 Availability in the Postnatal Murine Retina
    Yoshiyuki H, Szafranski K
    Front Cell Neurosci 2016,
  • lncRNA-Induced Nucleosome Repositioning Reinforces Transcriptional Repression of rRNA Genes upon Hypotonic Stress.
    Zhao Z, Dammert MA, Grummt I, Bierhoff H
    Cell Rep 2016, 14(8), 1876-82
  • Heat shock represses rRNA synthesis by inactivation of TIF-IA and lncRNA-dependent changes in nucleosome positioning.
    Zhao Z, Dammert MA, Hoppe S, Bierhoff H, Grummt I
    Nucleic Acids Res 2016, 44(17), 8144-52

Publications 2015:

  • Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer.
    Adams* PD, Jasper* H, Rudolph* KL
    Cell Stem Cell 2015, 16(6), 601-12 ** co-corresponding authors
  • Amyloid domains in the cell nucleus controlled by nucleoskeletal protein lamin B1 reveal a new pathway of mercury neurotoxicity.
    Arnhold F, Gührs KH, von Mikecz A
    PeerJ 2015, 3, e754
  • Stem Cells and Aging: What’s Next?
    Artandi SE, Blau HM, de Haan G, Geiger H, Goodell MA, Jones L, Levine RL, Munoz-Canoves P, Rodewald HR, Wagers A, Wang ZQ, Yamashita Y
    Cell Stem Cell 2015, 16, 578-81
  • Haemocytes control stem cell activity in the Drosophila intestine.
    Ayyaz A, Li H, Jasper H
    Nat Cell Biol 2015, 17(6), 736-48
  • Differential Regulation of MicroRNAs in End-Stage Failing Hearts Is Associated with Left Ventricular Assist Device Unloading.
    Barsanti C, Trivella MG, D'Aurizio R, El Baroudi M, Baumgart M, Groth M, Caruso R, Verde A, Botta L, Cozzi L, Pitto L
    Biomed Res Int 2015, 2015, 592512
  • Comparison of captive lifespan, age-associated liver neoplasias and age-dependent gene expression between two annual fish species: Nothobranchius furzeri and Nothobranchius korthause.
    Baumgart M, Di Cicco E, Rossi G, Cellerino A, Tozzini ET
    Biogerontology 2015, 16(1), 63-9
  • Elevated copper ion levels as potential cause of impaired kinesin-dependent transport processes.
    Böhm KJ
    Arch Toxicol 2015, 89(4), 565-72
  • Aluminium-induced kinesin inactivation as potential molecular cause of impairment of neuronal transport processes.
    Böhm KJ, Shabanpour M, Kalchishkova N
    Chem Res Toxicol 2015, 28(6), 1275-81
  • A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis.
    Buch S, Stickel F, Trépo E, Way M, Herrmann A, Nischalke HD, Brosch M, Rosendahl J, Berg T, Ridinger M, Rietschel M, McQuillin A, Frank J, Kiefer F, Schreiber S, Lieb W, Soyka M, Semmo N, Aigner E, Datz C, Schmelz R, Brückner S, Zeissig S, Stephan AM, Wodarz N, Devière J, Clumeck N, Sarrazin C, Lammert F, Gustot T, Deltenre P, Völzke H, Lerch MM, Mayerle J, Eyer F, Schafmayer C, Cichon S, Nöthen MM, Nothnagel M, Ellinghaus D, Huse K, Franke A, Zopf S, Hellerbrand C, Moreno C, Franchimont D, Morgan MY, Hampe J
    Nat Genet 2015, 47(12), 1443-8
  • Phenotypic regulation of the sphingosine 1-phosphate receptor Miles Apart by GRK2.
    Burczyk MS, Burkhalter MD, Blätte T, Matysik S, Caron MG, Barak LS, Philipp M
    Biochemistry 2015, 54(3), 765-75
  • Genome instability of ageing stem cells-Induction and defence mechanisms.
    Burkhalter MD, Rudolph KL, Sperka T
    Ageing Res Rev 2015, 23(Pt A), 29-36
  • Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA-binding site.
    Calviño FR, Kharde S, Ori A, Hendricks A, Wild K, Kressler D, Bange G, Hurt E, Beck M, Sinning I
    Nat Commun 2015, 6, 6510
  • Annual fishes of the genus Nothobranchius as an experimental model. p.93-99 in Annual Fishes
    Cellerino A
    In: Annual Fishes, Life History Strategy, Diversity and Evolution. (edited by Beiros N, García G, de Sá R) 2015, 93-99, CRC Press Taylor and Fran
  • Editorial for "Regulatory RNAs in the nervous system".
    Cellerino A, Bally-Cuif L, Pizzorusso T
    Front Cell Neurosci 2015, 9, 38
  • MicroRNA 19a replacement partially rescues fin and cardiac defects in zebrafish model of Holt Oram syndrome.
    Chiavacci E, D'Aurizio R, Guzzolino E, Russo F, Baumgart M, Groth M, Mariani L, D'Onofrio M, Arisi I, Pellegrini M, Cellerino A, Cremisi F, Pitto L
    Sci Rep 2015, 5, 18240
  • AKI Recovery Induced by Mesenchymal Stromal Cell-Derived Extracellular Vesicles Carrying MicroRNAs.
    Collino F, Bruno S, Incarnato D, Dettori D, Neri F, Provero P, Pomatto M, Oliviero S, Tetta C, Quesenberry PJ, Camussi G
    J Am Soc Nephrol 2015, 26(10), 2349-60
  • Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
    Dahms SO, Mayer MC, Roeser D, Multhaup G, Than ME
    Acta Crystallogr D Biol Crystallogr 2015, 71(Pt 3), 494-504
  • Signal integration by Ca(2+) regulates intestinal stem-cell activity.
    Deng H, Gerencser AA, Jasper H
    Nature 2015, 528(7581), 212-7
  • Mutants of Metal Binding Site M1 in APP E2 Show Metal Specific Differences in Binding of Heparin but Not of sorLA.
    Dienemann C, Coburger I, Mehmedbasic A, Andersen OM, Than ME
    Biochemistry 2015, 54(15), 2490-9
  • MicroRNAs provide the first evidence of genetic link between diapause and aging in vertebrates
    Dolfi* L, Baumgart* M, Groth M, Platzer M, Cellerino A
    bioRxiv 2015, * equal contribution
  • MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells.
    Doose G, Haake A, Bernhart SH, López C, Duggimpudi S, Wojciech F, Bergmann AK, Borkhardt A, Burkhardt B, Claviez A, Dimitrova L, Haas S, Hoell JI, Hummel M, Karsch D, Klapper W, Kleo K, Kretzmer H, Kreuz M, Küppers R, Lawerenz C, Lenze D, Loeffler M, Mantovani-Löffler L, Möller P, Ott G, Richter J, Rohde M, Rosenstiel P, Rosenwald A, Schilhabel M, Schneider M, Scholz I, Stilgenbauer S, Stunnenberg HG, Szczepanowski M, Trümper L, Weniger MA, ICGC MMML-Seq Consortium, Hoffmann S, Siebert R, Iaccarino I
    Proc Natl Acad Sci U S A 2015, 112(38), E5261-70
  • Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division.
    Dumont NA, Wang YX, von Maltzahn J, Pasut A, Bentzinger CF, Brun CE, Rudnicki MA
    Nat Med 2015, 21(12), 1455-63
  • SPLIFF: A Single-Cell Method to Map Protein-Protein Interactions in Time and Space.
    Dünkler A, Rösler R, Kestler HA, Moreno-Andrés D, Johnsson N
    Methods Mol Biol 2015, 1346, 151-68 published during change of institution
  • The butterfly plant arms-race escalated by gene and genome duplications.
    Edger PP, Heidel-Fischer HM, Bekaert M, Rota J, Glöckner G, Platts AE, Heckel DG, Der JP, Wafula EK, Tang M, Hofberger JA, Smithson A, Hall JC, Blanchette M, Bureau TE, Wright SI, dePamphilis CW, Schranz ME, Barker MS, Conant GC, Wahlberg N, Vogel H, Pires JC, Wheat CW
    Proc Natl Acad Sci U S A 2015, 112(27), 8362-6
  • Quality control mechanisms in cellular and systemic DNA damage responses.
    Ermolaeva** MA, Dakhovnik A, Schumacher** B
    Ageing Res Rev 2015, 23(Pt A), 3-11 ** co-corresponding authors
  • Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization.
    Eschbach J, von Einem B, Müller K, Bayer H, Scheffold A, Morrison BE, Rudolph KL, Thal DR, Witting A, Weydt P, Otto M, Fauler M, Liss B, McLean PJ, Spada ARL, Ludolph AC, Weishaupt JH, Danzer KM
    Ann Neurol 2015, 77(1), 15-32
  • Telomeres and Stem Cell Aging
    Felix DA
    In: Adult Stem Cells in Aging, Diseases and Cancer (edited by Rudolph KL), Else Kröner-Fresenius Symposia 2015, 5, 69-73, Karger Verlag, Basel
  • Stem Cells in Adult Intestine
    Feng J, Sperka T
    In: Adult Stem Cells in Aging, Diseases and Cancer (edited by Rudolph KL), Else Kröner-Fresenius Symposia 2015, 5, 18-24, Karger Verlag, Basel
  • Engineering a Constrained Peptidic Scaffold towards Potent and Selective Furin Inhibitors.
    Fittler H, Depp A, Avrutina O, Dahms SO, Than ME, Empting M, Kolmar H
    Chembiochem 2015, 16(17), 2441-4
  • VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice with Colitis.
    Foersch S, Sperka T, Lindner C, Taut A, Rudolph KL, Breier G, Boxberger F, Rau TT, Hartmann A, Stürzl M, Wittkopf N, Haep L, Wirtz S, Neurath MF, Waldner MJ
    Gastroenterology 2015, 149(1), 177-89
  • Conserved RNA secondary structures and long-range interactions in hepatitis C viruses.
    Fricke M, Dünnes N, Zayas M, Bartenschlager R, Niepmann M, Marz M
    RNA 2015, 21(7), 1219-32
  • Extended pairwise local alignment of wild card DNA/RNA sequences using dynamic programming
    Fürstenberg A, Maucher M, Kestler HA
    J Stat Comput Sim 2015, 85(1), 3-13 published during change of institution
  • Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold.
    Gaik M, Flemming D, von Appen A, Kastritis P, Mücke N, Fischer J, Stelter P, Ori A, Bui KH, Baßler J, Barbar E, Beck M, Hurt E
    J Cell Biol 2015, 208(3), 283-97
  • Snai1 represses Nanog to promote embryonic stem cell differentiation.
    Galvagni F, Neri F
    Genom Data 2015, 4, 82-3
  • Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes.
    Galvagni* F, Lentucci* C, Neri* F, Dettori D, De Clemente C, Orlandini M, Anselmi F, Rapelli S, Grillo M, Borghi S, Oliviero S
    Stem Cells 2015, 33(3), 742-50 * equal contribution
  • Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
    Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, William Rayner N, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, Thuillier D, Yengo L, Grallert H, Wahl S, Frånberg M, Strawbridge RJ, Kestler H, Chheda H, Eisele L, Gustafsson S, Steinthorsdottir V, Thorleifsson G, Qi L, Karssen LC, van Leeuwen EM, Willems SM, Li M, Chen H, Fuchsberger C, Kwan P, Ma C, Linderman M, Lu Y, Thomsen SK, Rundle JK, Beer NL, van de Bunt M, Chalisey A, Kang HM, Voight BF, Abecasis GR, Almgren P, Baldassarre D, Balkau B, Benediktsson R, Blüher M, Boeing H, Bonnycastle LL, Bottinger EP, Burtt NP, Carey J, Charpentier G, Chines PS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Doney ASF, Dorkhan M, Edkins S, Eriksson JG, Esko T, Eury E, Fadista J, Flannick J, Fontanillas P, Fox C, Franks PW, Gertow K, Gieger C, Gigante B, Gottesman O, Grant GB, Grarup N, Groves CJ, Hassinen M, Have CT, Herder C, Holmen OL, Hreidarsson AB, Humphries SE, Hunter DJ, Jackson AU, Jonsson A, Jørgensen ME, Jørgensen T, Kao WHL, Kerrison ND, Kinnunen L, Klopp N, Kong A, Kovacs P, Kraft P, Kravic J, Langford C, Leander K, Liang L, Lichtner P, Lindgren CM, Lindholm E, Linneberg A, Liu CT, Lobbens S, Luan J, Lyssenko V, Männistö S, McLeod O, Meyer J, Mihailov E, Mirza G, Mühleisen TW, Müller-Nurasyid M, Navarro C, Nöthen MM, Oskolkov NN, Owen KR, Palli D, Pechlivanis S, Peltonen L, Perry JRB, Platou CGP, Roden M, Ruderfer D, Rybin D, van der Schouw YT, Sennblad B, Sigurðsson G, Stančáková A, Steinbach G, Storm P, Strauch K, Stringham HM, Sun Q, Thorand B, Tikkanen E, Tonjes A, Trakalo J, Tremoli E, Tuomi T, Wennauer R, Wiltshire S, Wood AR, Zeggini E, Dunham I, Birney E, Pasquali L, Ferrer J, Loos RJF, Dupuis J, Florez JC, Boerwinkle E, Pankow JS, van Duijn C, Sijbrands E, Meigs JB, Hu FB, Thorsteinsdottir U, Stefansson K, Lakka TA, Rauramaa R, Stumvoll M, Pedersen NL, Lind L, Keinanen-Kiukaanniemi SM, Korpi-Hyövälti E, Saaristo TE, Saltevo J, Kuusisto J, Laakso M, Metspalu A, Erbel R, Jöcke KH, Moebus S, Ripatti S, Salomaa V, Ingelsson E, Boehm BO, Bergman RN, Collins FS, Mohlke KL, Koistinen H, Tuomilehto J, Hveem K, Njølstad I, Deloukas P, Donnelly PJ, Frayling TM, Hattersley AT, de Faire U, Hamsten A, Illig T, Peters A, Cauchi S, Sladek R, Froguel P, Hansen T, Pedersen O, Morris AD, Palmer CNA, Kathiresan S, Melander O, Nilsson PM, Groop LC, Barroso I, Langenberg C, Wareham NJ, O'Callaghan CA, Gloyn AL, Altshuler D, Boehnke M, Teslovich TM, McCarthy MI, Morris AP, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
    Nat Genet 2015, 47(12), 1415-25
  • Grundlagen der Durchflusszytometrie
    Gompf A
    In: Zelluläre Diagnostik und Therapie (edited by Sack U) 2015, 1-28, Walter de Gruyter GmbH, Be
  • Predicting Variabilities in Cardiac Gene Expression with a Boolean Network Incorporating Uncertainty.
    Grieb M, Burkovski A, Sträng JE, Kraus JM, Groß A, Palm G, Kühl M, Kestler HA
    PLoS One 2015, 10(7), e0131832
  • Novel Furin Inhibitors with Potent Anti-infectious Activity.
    Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T
    ChemMedChem 2015, 10(7), 1218-31
  • Core cross-linked nanogels based on the self-assembly of double hydrophilic poly(2-oxazoline) block copolymers
    Hartlieb M, Pretzel D, Wagner M, Hoeppener S, Bellstedt P, Görlach M, Englert C, Kempe K, Schubert US
    J Mater Chem B 2015, 3, 1748-59
  • Plasma N-acetyl-glucosaminidase in advanced gastro-intestinal adenocarcinoma correlates with age, stage and outcome.
    Hartmann D, von Figura G, Song Z, Harden S, Scott LC, Evans TJ, Rudolph KL, Bilsland AE, Keith WN
    Future Oncol 2015, 11(2), 193-203
  • Evolutionarily conserved signaling pathways: acting in the shadows of acute myelogenous leukemia's genetic diversity.
    Heidel FH, Arreba-Tutusaus P, Armstrong SA, Fischer T
    Clin Cancer Res 2015, 21(2), 240-8
  • Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response.
    Hein K, Mittler G, Cizelsky W, Kühl M, Ferrante F, Liefke R, Berger IM, Just S, Sträng JE, Kestler HA, Oswald F, Borggrefe T
    Sci Signal 2015, 8(369), ra30
  • A simple data-adaptive probabilistic variant calling model.
    Hoffmann S, Stadler PF, Strimmer K
    Algorithms Mol Biol 2015, 10, 10
  • High-throughput whole-genome sequencing of E14 mouse embryonic stem cells.
    Incarnato D, Neri F
    Genom Data 2015, 3, 6-7
  • Exploring the physiology and pathology of aging in the intestine of Drosophila melanogaster.
    Jasper H
    Invertebr Reprod Dev 2015, 59(sup1), 51-8
  • Proceedings of Reisensburg 2013 (Foreword).
    Kestler HA, Schmid M
    J Stat Comput Sim 2015, 85(1), 1-2
  • Polyketide synthesis genes associated with toxin production in two species of Gambierdiscus (Dinophyceae).
    Kohli GS, John U, Figueroa RI, Rhodes LL, Harwood DT, Groth M, Bolch CJS, Murray SA
    BMC Genomics 2015, 16, 410
  • NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis.
    Kondylis V, Polykratis A, Ehlken H, Ochoa-Callejero L, Straub BK, Krishna-Subramanian S, Van TM, Curth HM, Heise N, Weih F, Klein U, Schirmacher P, Kelliher M, Pasparakis M
    Cancer Cell 2015, 28(5), 582-98
  • Xlink Analyzer: software for analysis and visualization of cross-linking data in the context of three-dimensional structures.
    Kosinski J, von Appen A, Ori A, Karius K, Müller CW, Beck M
    J Struct Biol 2015, 189(3), 177-83
  • Alternative Splicing of SMPD1 in Human Sepsis.
    Kramer M, Quickert S, Sponholz C, Menzel U, Huse K, Platzer M, Bauer M, Claus RA
    PLoS One 2015, 10(4), e0124503
  • Exhaustive k-nearest-neighbour subspace clustering
    Krause JM, Lausser L, Kestler HA
    J Stat Comput Sim 2015, 85(1), 30–46 published during change of institution
  • DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control.
    Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Bergmann AK, Betts MJ, Carrillo-de-Santa-Pau E, Doose G, Gutwein J, Richter J, Hovestadt V, Huang B, Rico D, Jühling F, Kolarova J, Lu Q, Otto C, Wagener R, Arnolds J, Burkhardt B, Claviez A, Drexler HG, Eberth S, Eils R, Flicek P, Haas S, Humme M, Karsch D, Kerstens HHD, Klapper W, Kreuz M, Lawerenz C, Lenzek D, Loeffler M, López C, MacLeod RAF, Martens JHA, Kulis M, Martín-Subero JI, Möller P, Nage I, Picelli S, Vater I, Rohde M, Rosenstiel P, Rosolowski M, Russell RB, Schilhabel M, Schlesner M, Stadler PF, Szczepanowski M, Trümper L, Stunnenberg HG, Küppers R, Ammerpohl O, Lichter P, Siebert R, Hoffmann S, Radlwimmer B
    Nat Genet 2015, 47(11), 1316-25
  • Survival of primary, but not of cancer cells after combined Plk1-HDAC inhibition.
    Lange L, Hemmerich P, Spänkuch B
    Oncotarget 2015, 6(28), 25801-14
  • Defining the transcriptomic landscape of Candida glabrata by RNA-Seq.
    Linde J, Duggan S, Weber M, Horn F, Sieber P, Hellwig D, Riege K, Marz M, Martin R, Guthke R, Kurzai O
    Nucleic Acids Res 2015, 43(3), 1392-406
  • Genomic and epigenomic co-evolution in follicular lymphomas.
    Loeffler M, Kreuz M, Haake A, Hasenclever D, Trautmann H, Arnold C, Winter K, Koch K, Klapper W, Scholtysik R, Rosolowski M, Hoffmann S, Ammerpohl O, Szczepanowski M, Herrmann D, Küppers R, Pott C, Siebert R, HaematoSys-Project
    Leukemia 2015, 29(2), 456-63
  • Interventions to Slow Aging in Humans: Are We Ready?
    Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L
    Aging Cell 2015, 14(4), 497-510
  • Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells.
    Lu Y, Hardes K, Dahms SO, Böttcher-Friebertshäuser E, Steinmetzer T, Than ME, Klenk HD, Garten W
    Antiviral Res 2015, 120, 89-100
  • Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs).
    Mackmull MT, Iskar M, Parca L, Singer S, Bork P, Ori** A, Beck** M
    Mol Cell Proteomics 2015, 14(5), 1350-60 ** co-corresponding authors
  • Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.
    Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi VR, Ranjan S, Wolter J, Kohli S, Shahzad K, Heidel F, Krueger M, Schwenger V, Moeller MJ, Kalinski T, Reiser J, Chavakis T, Isermann B
    Nat Commun 2015, 6, 6496
  • Effects of ebselen and N-acetyl cysteine on replicative aging of primary human fibroblast strains.
    Marthandan S
    Immun Ageing 2015, 12, 8
  • Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts.
    Marthandan S, Priebe S, Baumgart M, Groth M, Cellerino A, Guthke R, Hemmerich P, Diekmann S
    Biomed Res Int 2015, 2015, 731938
  • Hormetic effect of rotenone in primary human fibroblasts.
    Marthandan S, Priebe S, Groth M, Guthke R, Platzer M, Hemmerich P, Diekmann S
    Immun Ageing 2015, 12, 11
  • MicroRNAs as biomarker of Parkinson disease? Small but mighty.
    Marz M, Ferracin M, Klein C
    Neurology 2015, 84(7), 636-8
  • Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy.
    Matthews LC, Berry AA, Morgan DJ, Poolman TM, Bauer K, Kramer F, Spiller DG, Richardson RV, Chapman KE, Farrow SN, Norman MR, Williamson AJK, Whetton AD, Taylor SS, Tuckermann JP, White MRH, Ray DW
    Proc Natl Acad Sci U S A 2015, 112(17), 5479-84
  • CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo.
    Mende N, Kuchen EE, Lesche M, Grinenko T, Kokkaliaris KD, Hanenberg H, Lindemann D, Dahl A, Platz A, Höfer T, Calegari F, Waskow C
    J Exp Med 2015, 212(8), 1171-83
  • Comprehensive insights in the Mycobacterium avium subsp. paratuberculosis genome using new WGS data of sheep strain JIII-386 from Germany.
    Möbius P, Hölzer M, Felder M, Nordsiek G, Groth M, Köhler H, Reichwald K, Platzer M, Marz M
    Genome Biol Evol 2015, 7(9), 2585-601
  • Mechanism of Functional Alterations in Hematopoietic Stem Cell Aging
    Morita Y
    In: Adult Stem Cells in Aging, Diseases and Cancer (edited by Rudolph KL), Else Kröner-Fresenius Symposia 2015, 5, 40-59, Karger Verlag, Basel
  • Space constraints govern fate of hematopoietic stem and progenitor cells in vitro.
    Müller E, Grinenko T, Pompe T, Waskow C, Werner C
    Biomaterials 2015, 53, 709-15
  • The function of embryonic stem cell-expressed Ras (E-Ras), a unique Ras family member, correlates with its additional motifs and its structural properties.
    Nakhaei-Rad S, Nakhaeizadeh H, Kordes C, Cirstea IC, Schmick M, Dvorsky R, Bastiaens PIH, Häussinger D, Ahmadian MR
    J Biol Chem 2015, 290(25), 15892-903
  • Cooperative development of logical modelling standards and tools with CoLoMoTo.
    Naldi A, Monteiro PT, Müssel C, the Consortium for Logical Models and Tools, Kestler HA, Thieffry D, Xenarios I, Saez-Rodriguez J, Helikar T, Chaouiya C
    Bioinformatics 2015, 31(7), 1154-9
  • TET1 is a tumour suppressor that inhibits colon cancer growth by derepressing inhibitors of the WNT pathway.
    Neri F, Dettori D, Incarnato D, Krepelova A, Rapelli S, Maldotti M, Parlato C, Paliogiannis P, Oliviero S
    Oncogene 2015, 34(32), 4168-76
  • TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues.
    Neri F, Incarnato D, Krepelova A, Dettori D, Rapelli S, Maldotti M, Parlato C, Anselmi F, Galvagni F, Oliviero S
    Nucleic Acids Res 2015, 43(14), 6814-26
  • DNA methylation and demethylation dynamics.
    Neri F, Incarnato D, Oliviero S
    Oncotarget 2015, 6(33), 34049-50
  • Murine Embryonic Stem Cells Synthesize Retinoic Acid to Promote their Own Differentiation
    Neri* F, De Clemente* C, Orlandini M, Lentucci C, Anselmi F, Galvagni F
    J Stem Cell Res Ther 2015, 5(7), 293 * equal contribution
  • Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine Reveals Promoter DNA Methylation Dynamics.
    Neri* F, Incarnato* D, Krepelova A, Rapelli S, Anselmi F, Parlato C, Medana C, Dal Bello F, Oliviero S
    Cell Rep 2015, 10(5), 674–683 * equal contribution
  • Of flies, mice, and men: evolutionarily conserved tissue damage responses and aging.
    Neves J, Demaria M, Campisi J, Jasper H
    Dev Cell 2015, 32(1), 9-18
  • Stat5 gene dosage in T cells modulates CD8+ T-cell homeostasis and attenuates contact hypersensitivity response in mice.
    Nivarthi H, Prchal-Murphy M, Swoboda A, Hager M, Schlederer M, Kenner L, Tuckermann J, Sexl V, Moriggl R, Ermakova O
    Allergy 2015, 70(1), 67-79 published during change of institution
  • Identification of ageing-associated naturally occurring peptides in human urine.
    Nkuipou-Kenfack E, Bhat A, Klein J, Jankowski V, Mullen W, Vlahou A, Dakna M, Koeck T, Schanstra JP, Zürbig P, Rudolph KL, Schumacher B, Pich A, Mischak H
    Oncotarget 2015, 6(33), 34106-17
  • Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats
    Ori* A, Toyama* BH, Harris MS, Bock T, Iskar M, Bork P, Ingolia NT, Hetzer MW, Beck M
    Cell Syst 2015, 1(3), 224–237 * equal contribution, published during change of institution
  • High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation.
    Parplys AC, Seelbach JI, Becker S, Behr M, Jend C, Mansour WY, Joosse S, Stuerzbecher HW, Pospiech H, Petersen C, Dikomey E, Borgmann K
    Cell Cycle 2015, 14(19), 3190-202
  • Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44
    Parra* LM, Hartmann* M, Schubach S, Li Y, Herrlich P, Herrlich A
    Mol Cell Biol 2015, 35(19), 3381-95 * equal contribution
  • Deficiency of the protein-tyrosine phosphatase DEP-1/PTPRJ promotes matrix metalloproteinase-9 expression in meningioma cells.
    Petermann A, Stampnik Y, Cui Y, Morrison H, Pachow D, Kliese N, Mawrin C, Böhmer FD
    J Neurooncol 2015, 122(3), 451-9
  • Characterization and quantification of proteins secreted by single human embryos prior to implantation.
    Poli* M, Ori* A, Child T, Jaroudi S, Spath K, Beck M, Wells D
    EMBO Mol Med 2015, 7(11), 1465-79 * equal contribution, published during change of institution
  • Glandular ß-glucosidases in juvenile Chrysomelina leaf beetles support the evolution of a host-plant-dependent chemical defense.
    Rahfeld P, Haeger W, Kirsch R, Pauls G, Becker T, Schulze E, Wielsch N, Wang D, Groth M, Brandt W, Boland W, Burse A
    Insect Biochem Mol Biol 2015, 58, 28-38
  • Turquoise killifish.
    Reichard M, Cellerino A, Valenzano DR
    Curr Biol 2015, 25(17), R741-2
  • The deubiquitinating enzyme CYLD regulates the differentiation and maturation of thymic medullary epithelial cells.
    Reissig S, Hövelmeyer N, Tang Y, Weih D, Nikolaev A, Riemann M, Weih F, Waisman A
    Immunol Cell Biol 2015, 93(6), 558-66
  • The Epigenome of Schistosoma mansoni Provides Insight about How Cercariae Poise Transcription until Infection.
    Roquis D, Lepesant JMJ, Picard MAL, Freitag M, Parrinello H, Groth M, Emans R, Cosseau C, Grunau C
    PLoS Negl Trop Dis 2015, 9(8), e0003853
  • Adult Stem Cells in Aging, Diseases and Cancer
    Rudolph KL (ed)
    Book series: Else Kröner-Fresenius Symposia 2015, 5, Karger Verlag, Basel, Switzerlan
  • Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition.
    Russell R, Perkhofer L, Liebau S, Lin Q, Lechel A, Feld FM, Hessmann E, Gaedcke J, Güthle M, Zenke M, Hartmann D, von Figura G, Weissinger SE, Rudolph KL, Möller P, Lennerz JK, Seufferlein T, Wagner M, Kleger A
    Nat Commun 2015, 6, 7677
  • Towards a comprehensive picture of alloacceptor tRNA remolding in metazoan mitochondrial genomes.
    Sahyoun AH, Hölzer M, Jühling F, Höner zu Siederdissen C, Al-Arab M, Tout K, Marz M, Middendorf M, Stadler PF, Bernt M
    Nucleic Acids Res 2015, 43(16), 8044-56
  • Central Venous Catheter-Related Bloodstream Infections in Obese Hematologic Patients.
    Schalk E, Färber J, Fischer T, Heidel FH
    Infect Control Hosp Epidemiol 2015, 36(8), 995-6
  • Prediction of central venous catheter-related bloodstream infections (CRBSIs) in patients with haematologic malignancies using a modified Infection Probability Score (mIPS).
    Schalk E, Hanus L, Färber J, Fischer T, Heidel FH
    Ann Hematol 2015, 94(9), 1451-6
  • On the validity of time-dependent AUC estimators.
    Schmid M, Kestler HA, Potapov S
    Brief Bioinform 2015, 16(1), 153-68 published during change of institution
  • Epo-induced erythroid maturation is dependent on Plcγ1 signaling.
    Schnöder TM, Arreba-Tutusaus P, Griehl I, Bullinger L, Buschbeck M, Lane SW, Döhner K, Plass C, Lipka DB, Heidel FH, Fischer T
    Cell Death Differ 2015, 22(6), 974-85
  • Mast cell promotion of T cell-driven antigen-induced arthritis despite being dispensable for antibody-induced arthritis in which T cells are bypassed.
    Schubert N, Dudeck J, Liu P, Karutz A, Speier S, Maurer M, Tuckermann J, Dudeck A
    Arthritis Rheumatol 2015, 67(4), 903-13 published during change of institution
  • High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation.
    Sokka M, Rilla K, Miinalainen I, Pospiech H, Syväoja JE
    Nucleic Acids Res 2015, 43(10), 4975-89
  • It's a bit over, is that ok? The subtle surplus from tandem alternative splicing.
    Szafranski K, Kramer M
    RNA BIOL 2015, 12(2), 115-22
  • Sestrins in Aging and Metabolism
    Tang D, Tao S
    In: Adult Stem Cells in Aging, Diseases and Cancer (edited by Rudolph KL), Else Kröner-Fresenius Symposia 2015, 5, 60-65, Karger Verlag, Basel
  • Internalization of near-infrared fluorescently labeled activatable cell-penetrating peptide and of proteins into human fibrosarcoma cell line HT-1080.
    Tansi F, Kallweit E, Kaether C, Kappe K, Schumann C, Hilger I, Reissmann S
    J Cell Biochem 2015, 116(7), 1222-31
  • Left-right asymmetry in the light of TOR: An update on what we know so far.
    Tena TC, Burkhalter** MD, Philipp** M
    Biol Cell 2015, 107(9), 306-18 ** co-corresponding authors
  • A Branch-and-Bound Approach for Tautomer Enumeration
    Thalheim T, Wagner B, Kühne R, Middendorf M, Schüürmann G
    Mol Inform 2015, 34, 263–75
  • Analysis of Alpha-2 Macroglobulin from the Long-Lived and Cancer-Resistant Naked Mole-Rat and Human Plasma.
    Thieme R, Kurz S, Kolb M, Debebe T, Holtze S, Morhart M, Huse K, Szafranski K, Platzer M, Hildebrandt TB, Birkenmeier G
    PLoS One 2015, 10(6), e0130470
  • A pooled analysis of overall survival in COMFORT-I and COMFORT-II, 2 randomized phase III trials of ruxolitinib for the treatment of myelofibrosis.
    Vannucchi AM, Kantarjian HM, Kiladjian JJ, Gotlib J, Cervantes F, Mesa RA, Sarlis NJ, Peng W, Sandor V, Gopalakrishna P, Hmissi A, Stalbovskaya V, Gupta V, Harrison C, Verstovsek S, COMFORT Investigators
    Haematologica 2015, 100(9), 1139-45
  • Sputnik: Ad hoc distributed computation.
    Völkel G, Lausser L, Schmid F, Kraus JM, Kestler HA
    Bioinformatics 2015, 31(8), 1298-301
  • In situ structural analysis of the human nuclear pore complex.
    von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L, Kastritis P, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, Bork P, Antonin W, Glavy JS, Bui KH, Beck M
    Nature 2015, 526(7571), 140-3 published during change of institution
  • A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer.
    von Eyss B, Jaenicke LA, Kortlever RM, Royla N, Wiese KE, Letschert S, McDuffus LA, Sauer M, Rosenwald A, Evan GI, Kempa S, Eilers M
    Cancer Cell 2015, 28(6), 743-57
  • The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma.
    Wagener R, Aukema SM, Schlesner M, Haake A, Burkhardt B, Claviez A, Drexler HG, Hummel M, Kreuz M, Loeffler M, Rosolowski M, López C, Möller P, Richter J, Rohde M, Betts MJ, Russell RB, Bernhart SH, Hoffmann S, Rosenstiel P, Schilhabel M, Szczepanowski M, Trümper L, Klapper W, Siebert R, ICGC MMML-Seq-Project, "Molecular Mechanisms in Malignant Lymphomas" Network Project of the Deutsche Krebshilfe
    Genes Chromosomes Cancer 2015, 54(9), 555-64
  • Sumoylation of HDAC2 promotes NF-κB-dependent gene expression.
    Wagner T, Kiweler N, Wolff K, Knauer SK, Brandl A, Hemmerich P, Dannenberg JH, Heinzel T, Schneider G, Krämer OH
    Oncotarget 2015, 6(9), 7123-35
  • PERK Limits Drosophila Lifespan by Promoting Intestinal Stem Cell Proliferation in Response to ER Stress.
    Wang L, Ryoo HD, Qi Y, Jasper H
    PLoS Genet 2015, 11(5), e1005220
  • Structure and regulatory role of the C-terminal winged helix domain of the archaeal minichromosome maintenance complex.
    Wiedemann C, Szambowska A, Häfner S, Ohlenschläger O, Gührs KH, Görlach M
    Nucleic Acids Res 2015, 43(5), 2958-67
  • Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells.
    Wiese* KE, Haikala* HM, von Eyss* B, Wolf E, Esnault C, Rosenwald A, Treisman R, Klefström J, Eilers M
    EMBO J 2015, 34(11), 1554-71 * equal contribution
  • Generation of Aorta Transcript Atlases of Wild-Type and Apolipoprotein E-null Mice by Laser Capture Microdissection-Based mRNA Expression Microarrays.
    Yin C, Mohanta S, Ma Z, Weber C, Hu D, Weih F, Habenicht A
    Methods Mol Biol 2015, 1339, 297-308
  • Inhibition of Wild-type p53-induced phosphatase 1 promotes liver regeneration in mice by direct activation of mTOR.
    Zhang L, Liu L, He Z, Li G, Liu J, Song Z, Jin H, Rudolph KL, Yang H, Mao Y, Zhang L, Zhang H, Xiao Z, Ju Z
    Hepatology 2015, 61(6), 2030-41
  • Merlin's wizardry guides cohesive migration.
    Zoch A, Morrison H
    Nat Cell Biol 2015, 17(3), 212-3

Publications 2014:

  • A sequence-ready physical map of barley anchored genetically by two million single-nucleotide polymorphisms.
    Ariyadasa R, Mascher M, Nussbaumer T, Schulte D, Frenkel Z, Poursarebani N, Zhou R, Steuernagel B, Gundlach H, Taudien S, Felder M, Platzer M, Himmelbach A, Schmutzer T, Hedley P, Muehlbauer G, Scholz U, Korol A, Mayer K, Waugh R, Langridge P, Graner A, Stein N
    Plant Physiol 2014, 164(1), 412-23
  • HSP90 supports tumor growth and angiogenesis through PRKD2 protein stabilization.
    Azoitei N, Diepold K, Brunner C, Rouhi A, Genze F, Becher A, Kestler H, van Lint J, Chiosis G, Koren J, Fröhling S, Scholl C, Seufferlein T
    Cancer Res 2014, 74(23), 7125-36 published during change of institution
  • Transcriptomic immune response of the cotton stainer Dysdercus fasciatus to experimental elimination of vitamin-supplementing intestinal symbionts.
    Bauer E, Salem H, Marz M, Vogel H, Kaltenpoth M
    PLoS One 2014, 9(12), e114865
  • RNA-seq of the aging brain in the short-lived fish N. furzeri - conserved pathways and novel genes associated with neurogenesis.
    Baumgart* M, Groth* M, Priebe* S, Savino A, Testa G, Dix A, Ripa R, Spallotta F, Gaetano C, Ori M, Terzibasi Tozzini E, Guthke R, Platzer M, Cellerino A
    Aging Cell 2014, 13(6), 965-74 * equal contribution
  • Explorative Analysis of Heterogeneous, Unstructured, and Uncertain Data: A Computer Science Perspective on Biodiversity Research
    Beckstein C, Böcker S, Bogdan M, Bücker HM.Bruelheide H, Denzler J, Dittrich P, Grosse I, Hinneburg A, König-Ries B, Löffler F, Marz M, Müller-Hannemann M, Winter M, Zimmermann W
    In: Proceedings of 3rd International Conference on Data Management Technologies and Applications (DATA-2014) 2014, 251-257, Science and Technology
  • Impact of genomic damage and ageing on stem cell function.
    Behrens A, van Deursen JM, Rudolph* KL, Schumacher B
    Nat Cell Biol 2014, 16(3), 201-7 * corresponding author, based on the Else Kröner-Fresenius-Symposium in Molecular Medicine
  • Analysis of disorder in tricalcium silicate by 29Si NMR spectroscopy and additional methods
    Bellmann F, Leppert J, Görlach M, Krbetschek M, Damidot D, Ludwig HM
    Cement Concrete Res 2014, 57, 105-16
  • Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength.
    Bentzinger* CF, von Maltzahn* J, Dumont NA, Stark DA, Wang YX, Nhan K, Frenette J, Cornelison DDW, Rudnicki MA
    J Cell Biol 2014, 205(1), 97-111 * equal contribution, published during change of institution
  • Slit/Robo signaling regulates cell fate decisions in the intestinal stem cell lineage of Drosophila.
    Biteau B, Jasper H
    Cell Rep 2014, 7(6), 1867-75
  • Chlamydia psittaci inclusion membrane protein IncB associates with host protein Snapin.
    Böcker S, Heurich A, Franke C, Monajembashi S, Sachse K, Saluz HP, Hänel F
    Int J Med Microbiol 2014, 304(5-6), 542-53
  • Kinesin-dependent motility generation as target mechanism of cadmium intoxication.
    Böhm KJ
    Toxicol Lett 2014, 224(3), 356-61
  • Novel Insights into Structure and Function of Factor XIIIa-Inhibitor Tridegin.
    Böhm M, Bäuml CA, Hardes K, Steinmetzer T, Roeser D, Schaub Y, Than ME, Biswas A, Imhof D
    J Med Chem 2014, 57(24), 10355-65
  • The Wilms' tumor suppressor WT1 enhances CD95L expression and promotes activation-induced cell death in leukemic T cells.
    Bourkoula K, Englert C, Giaisi M, Koehler R, Krammer PH, Li-Weber M
    Int J Cancer 2014, 134(2), 291-300
  • A 'telomere-associated secretory phenotype' cooperates with BCR-ABL to drive malignant proliferation of leukemic cells.
    Braig M, Pällmann N, Preukschas M, Steinemann D, Hofmann W, Gompf A, Streichert T, Braunschweig T, Copland M, Rudolph KL, Bokemeyer C, Koschmieder S, Schuppert A, Balabanov S, Brümmendorf TH
    Leukemia 2014, 28(10), 2028-39
  • Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy.
    Bruedigam C, Bagger FO, Heidel FH, Paine Kuhn C, Guignes S, Song A, Austin R, Vu T, Lee E, Riyat S, Moore AS, Lock RB, Bullinger L, Hill GR, Armstrong SA, Williams DA, Lane SW
    Cell Stem Cell 2014, 15(6), 775-90
  • Lin28a - boost your energy for youthful regeneration.
    Burkhalter MD, Morita Y, Rudolph KL
    EMBO J 2014, 33(1), 5–6
  • Control of metabolic adaptation to fasting by dILP6-induced insulin signaling in Drosophila oenocytes.
    Chatterjee D, Katewa SD, Qi Y, Jackson SA, Kapahi P, Jasper H
    Proc Natl Acad Sci U S A 2014, 111(50), 17959-64
  • Gadd45a Regulates Hematopoietic Stem Cell Stress Responses in Mice.
    Chen Y, Ma X, Zhang M, Wang X, Wang C, Wang H, Guo P, Yuan W, Rudolph KL, Zhan Q, Ju Z
    Blood 2014, 123(6), 851-62
  • Kit regulates HSC engraftment across the human-mouse species barrier.
    Cosgun KN, Rahmig S, Mende N, Reinke S, Hauber I, Schäfer C, Petzold A, Weisbach H, Heidkamp G, Purbojo A, Cesnjevar R, Platz A, Bornhäuser M, Schmitz M, Dudziak D, Hauber J, Kirberg J, Waskow C
    Cell Stem Cell 2014, 15(2), 227-38
  • Nerve growth factor in the adult brain of a teleostean model for aging research: Nothobranchius furzeri.
    D'Angelo L, Castaldo L, Cellerino A, de Girolamo P, Lucini C
    Ann Anat 2014, 196(4), 183-91
  • Brain derived neurotrophic factor: mRNA expression and protein distribution in the brain of the teleost Nothobranchius furzeri.
    D'Angelo L, de Girolamo P, Lucini C, Terzibasi ET, Baumgart M, Castaldo L, Cellerino A
    J Comp Neurol 2014, 522(5), 1004-30
  • X-ray structures of human furin in complex with competitive inhibitors.
    Dahms SO, Hardes K, Becker GL, Steinmetzer T, Brandstetter H, Than ME
    ACS Chem Biol 2014, 9(5), 1113-18
  • FACS-FRET: Reply to comments on "Biomolecular dynamics and binding studies in the living cell".
    Diekmann S, Hoischen C
    Phys Life Rev 2014, 11(1), 38
  • Biomolecular dynamics and binding studies in the living cell.
    Diekmann S, Hoischen C
    Phys Life Rev 2014, 11(1), 1-30
  • Transition to annual life history coincides with reduction in cell cycle speed during early cleavage in three independent clades of annual killifish.
    Dolfi L, Ripa R, Cellerino A
    Evodevo 2014, 5, 32
  • Expression of the lymphoid enhancer factor 1 is required for normal hematopoietic stem and progenitor cell function.
    Edmaier KE, Stahnke K, Vegi N, Mulaw M, Ihme S, Scheffold A, Rudolph KL, Buske C
    Leukemia 2014, 28(1), 227-30 published during change of institution
  • The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells.
    Eguether T, Ermolaeva MA, Zhao Y, Bonnet MC, Jain A, Pasparakis M, Courtois G, Tassin AM
    Nat Commun 2014, 5, 4585
  • Systemic DNA damage responses: organismal adaptations to genome instability.
    Ermolaeva MA, Schumacher B
    Trends Genet 2014, 30(3), 95-102
  • Insights from the worm: the C. elegans model for innate immunity.
    Ermolaeva MA, Schumacher B
    Semin Immunol 2014, 26(4), 303-9
  • Functional Mutation Analysis Provides Evidence for a Role of REEP1 in Lipid Droplet Biology.
    Falk J, Rohde M, Bekhite MM, Sophie Neugebauer, Hemmerich P, Kiehntopf M, Deufel T, Hübner CA, Beetz C
    Hum Mutat 2014, 35(4), 497-504
  • Hypoxia controls Flvcr1 gene expression in Caco2 cells through HIF2α and ETS1.
    Fiorito V, Neri F, Pala V, Silengo L, Oliviero S, Altruda F, Tolosano E
    Biochim Biophys Acta 2014, 1839(4), 259-64
  • Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis.
    Flex E, Jaiswal M, Pantaleoni F, Martinelli S, Strullu M, Fansa EK, Caye A, De Luca A, Lepri F, Dvorsky R, Pannone L, Paolacci S, Zhang SC, Fodale V, Bocchinfuso G, Rossi C, Burkitt-Wright EMM, Farrotti A, Stellacci E, Cecchetti S, Ferese R, Bottero L, Castro S, Fenneteau O, Brethon B, Sanchez M, Roberts AE, Yntema HG, Van Der Burgt I, Cianci P, Bondeson ML, Cristina Digilio M, Zampino G, Kerr B, Aoki Y, Loh ML, Palleschi A, Di Schiavi E, Carè A, Selicorni A, Dallapiccola B, Cirstea IC, Stella L, Zenker M, Gelb BD, Cavé H, Ahmadian MR, Tartaglia M
    Hum Mol Genet 2014, 23(16), 4315-27
  • Brain derived neurotrophic factor in the retina of the teleost N. furzeri.
    Gatta C, Castaldo L, Cellerino A, de Girolamo P, Lucini C, D'Angelo L
    Ann Anat 2014, 196(4), 192-6
  • The Genome of the Foraminiferan Reticulomyxa filosa.
    Glöckner G, Hülsmann N, Schleicher M, Noegel AA, Eichinger L, Gallinger C, Pawlowski J, Sierra R, Euteneuer U, Pillet L, Moustafa A, Platzer M, Groth M, Szafranski K, Schliwa M
    Curr Biol 2014, 24, 11-8
  • Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells.
    Grinenko T, Arndt K, Portz M, Mende N, Günther M, Cosgun KN, Alexopoulou D, Lakshmanaperumal N, Henry I, Dahl A, Waskow C
    J Exp Med 2014, 211(2), 209-15
  • The genome of an influenza virus from a pilot whale: Relation to influenza viruses of gulls and marine mammals.
    Groth M, Lange J, Kanrai P, Pleschka S, Scholtissek C, Krumbholz A, Platzer M, Sauerbrei A, Zell R
    Infect Genet Evol 2014, 24, 183-6
  • Transkriptom-Sequenzierung in der Alternsforschung
    Groth M, Reichwald K, Szafranski K, Taudien S, Platzer M
    BIOspektrum 2014, 20(2), 163-6
  • PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan.
    Guo L, Karpac J, Tran SL, Jasper H
    Cell 2014, 156(1-2), 109-22
  • Manganese-Enhanced MRI: In Vivo Imaging of CNS Anatomy, Fiber Connectivity and Functional Activity
    Haenold R
    In: In Vivo Imaging: New Research (edited by Rick Hough and Jared Camarillo), Biotechnology in Agriculture, Industry and Medicine 2014, 49-86, Nova Science Publishers
  • Studying aging in Drosophila.
    He Y, Jasper H
    Methods 2014, 68(1), 129-33
  • A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection.
    Hoffmann S, Otto C, Doose G, Tanzer A, Langenberger D, Christ S, Kunz M, Holdt LM, Teupser D, Hackermüller J, Stadler PF
    Genome Biol 2014, 15(2), R34
  • AgeFactDB – The JenAge Ageing Factor Database – Towards data integration in ageing research
    Huehne R, Thalheim T, Suehnel J
    Nucleic Acids Res 2014, 42(1), D892-6
  • Telomerase exerts physiological and tumor promoting functions by stimulating ribosomal biogenesis
    Iben S, Günes C
    Telomere and Telomerases 2014, 1, e433
  • Mutation in ST6GALNAC5 identified in family with coronary artery disease.
    Inanloorahatloo K, Parsa AFZ, Huse K, Rasooli P, Davaran S, Platzer M, Kramer M, Fan JB, Turk C, Amini S, Steemers F, Gunderson K, Ronaghi M, Elahi E
    Sci Rep 2014, 4, 3595
  • High-throughput single nucleotide variant discovery in E14 mouse embryonic stem cells provides a new reference genome assembly.
    Incarnato D, Krepelova A, Neri F
    Genomics 2014, 104(2), 121-7
  • Genome-wide profiling of mouse RNA secondary structures reveals key features of the mammalian transcriptome.
    Incarnato D, Neri F, Anselmi F, Oliviero S
    Genome Biol 2014, 15(10), 491
  • Functional crosstalk between Ras and Rho pathways: p120RasGAP competitively inhibits the RhoGAP activity of Deleted in Liver Cancer (DLC) tumor suppressors by masking its catalytic arginine finger.
    Jaiswal M, Dvorsky R, Amin E, Risse SL, Fansa EK, Zhang SC, Taha MS, Gauhar AR, Nakhaei-Rad S, Kordes C, Koessmeier KT, Cirstea IC, Olayioye MA, Haeussinger D, Ahmadian MR
    J Biol Chem 2014, 289(10), 6839-49
  • Mitochondrial proteostasis in the control of aging and longevity.
    Jensen MB, Jasper H
    Cell Metab 2014, 20(2), 214-25
  • Telomere shortening in leukocyte subpopulations in depression.
    Karabatsiakis A, Kolassa IT, Kolassa S, Rudolph KL, Dietrich DE
    BMC Psychiatry 2014, 14, 192
  • Transduction of proteins into leishmania tarentolae by formation of non-covalent complexes with cell-penetrating peptides.
    Keller AA, Breitling R, Hemmerich P, Kappe K, Braun M, Wittig B, Schaefer B, Lorkowski S, Reissmann S
    J Cell Biochem 2014, 115(2), 243-52
  • Sensory neuropathy with bone destruction due to a mutation in the membrane-shaping atlastin GTPase 3.
    Kornak U, Mademan I, Schinke M, Voigt M, Krawitz P, Hecht J, Barvencik F, Schinke T, Gießelmann S, Beil FT, Pou-Serradell A, Vílchez JJ, Beetz C, Deconinck T, Timmerman V, Kaether C, De Jonghe P, Hübner CA, Gal A, Amling M, Mundlos S, Baets J, Kurth I
    Brain 2014, 137(Pt 3), 683-92
  • Myc and max genome-wide binding sites analysis links the Myc regulatory network with the polycomb and the core pluripotency networks in mouse embryonic stem cells.
    Krepelova* A, Neri* F, Maldotti M, Rapelli S, Oliviero S
    PLoS One 2014, 9(2), e88933 * equal contribution
  • The origin of the European avian-like swine influenza viruses.
    Krumbholz A, Lange J, Sauerbrei A, Groth M, Platzer M, Kanrai P, Pleschka S, Scholtissek C, Büttner M, Dürrwald R, Zell R
    J Gen Virol 2014, 95(Pt11), 2372-6
  • Virus isolate from carp: genetic characterisation reveals a novel picornavirus with two aphthovirus 2A-like sequences.
    Lange J, Groth M, Fichtner D, Granzow H, Keller B, Walther M, Platzer M, Sauerbrei A, Zell R
    J Gen Virol 2014, 95, 80-90
  • Circulation of classical swine influenza virus in Europe between the wars?
    Lange J, Groth M, Kanrai P, Pleschka S, Scholtissek C, Dürrwald R, Platzer M, Sauerbrei A, Zell R
    Arch Virol 2014, 159(6), 1467-73
  • Unlabeling data can improve classification accuracy
    Lausser L, Schmid F, Schmid M, Kestler HA
    Pattern Recogn Lett 2014, 37, 15–23
  • Enhanced Telomere Rejuvenation in Pluripotent Cells Reprogrammed via Nuclear Transfer Relative to Induced Pluripotent Stem Cells.
    Le R, Kou Z, Jiang Y, Li M, Huang B, Liu W, Li H, Kou X, He W, Rudolph KL, Ju Z, Gao S
    Cell Stem Cell 2014, 14(1), 27-39
  • Genomewide comparison and novel ncRNAs of Aquificales.
    Lechner M, Nickel AI, Wehner S, Riege K, Wieseke N, Beckmann BM, Hartmann** RK, Marz** M
    BMC Genomics 2014, 15, 522 ** co-corresponding authors
  • Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.
    Lee T, Di Paola D, Malina A, Mills JR, Kreps A, Grosse F, Tang H, Zannis-Hadjopoulos M, Larsson O, Pelletier J
    J Biol Chem 2014, 289(33), 22798-814
  • Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features.
    Lessel D, Vaz B, Halder S, Lockhart PJ, Marinovic-Terzic I, Lopez-Mosqueda J, Philipp M, Sim JCH, Smith KR, Oehler J, Cabrera E, Freire R, Pope K, Nahid A, Norris F, Leventer RJ, Delatycki MB, Barbi G, von Ameln S, Högel J, Degoricija M, Fertig R, Burkhalter MD, Hofmann K, Thiele H, Altmüller J, Nürnberg G, Nürnberg P, Bahlo M, Martin GM, Aalfs CM, Oshima J, Terzic J, Amor DJ, Dikic I, Ramadan K, Kubisch C
    Nat Genet 2014, 11, 1239-44
  • RNA structure analysis of alphacoronavirus terminal genome regions.
    Madhugiri R, Fricke M, Marz M, Ziebuhr J
    Virus Res 2014, 194, 76-89
  • p21 promotes sustained liver regeneration and hepatocarcinogenesis in chronic cholestatic liver injury.
    Marhenke S, Buitrago-Molina LE, Endig J, Orlik J, Schweitzer N, Klett S, Longerich T, Geffers R, Sánchez Muñoz A, Dorrell C, Katz SF, Lechel A, Weng H, Krech T, Lehmann U, Dooley S, Rudolph KL, Manns MP, Vogel A
    Gut 2014, 63(9), 1501-12
  • SENIEUR status of the originating cell donor negates certain 'anti-immunosenescence' effects of ebselen and N-acetyl cysteine in human T cell clone cultures.
    Marthandan S, Freeburn R, Steinbrecht S, Pawelec G, Barnett Y
    Immun Ageing 2014, 11(1), 17
  • Challenges in RNA virus bioinformatics.
    Marz M, Beerenwinkel N, Drosten C, Fricke M, Frishman D, Hofacker IL, Hoffmann D, Middendorf M, Rattei T, Stadler PF, Töpfer A
    Bioinformatics 2014, 30(13), 1793-9
  • Novel Zinc-binding Site in the E2 Domain Regulates Amyloid Precursor-like Protein 1 (APLP1) Oligomerization.
    Mayer MC, Kaden D, Schauenburg L, Hancock MA, Voigt P, Roeser D, Barucker C, Than ME, Schaefer M, Multhaup G
    J Biol Chem 2014, 289(27), 19019-30
  • Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice.
    Missios P, Zhou Y, Guachalla LM, von Figura G, Wegner A, Chakkarappan SR, Binz T, Gompf A, Hartleben G, Burkhalter MD, Wulff V, Günes C, Sattler RW, Song Z, Illig T, Klaus S, Böhm BO, Wenz T, Hiller K, Rudolph KL
    Nat Commun 2014, 5, 4924
  • Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures.
    Movérare-Skrtic S, Henning P, Liu X, Nagano K, Saito H, Börjesson AE, Sjögren K, Windahl SH, Farman H, Kindlund B, Engdahl C, Koskela A, Zhang FP, Eriksson EE, Zaman F, Hammarstedt A, Isaksson H, Bally M, Kassem A, Lindholm C, Sandberg O, Aspenberg P, Sävendahl L, Feng JQ, Tuckermann J, Tuukkanen J, Poutanen M, Baron R, Lerner UH, Gori F, Ohlsson C
    Nat Med 2014, 20(11), 1279-88 published during change of institution
  • DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage.
    Mueller MM, Castells-Roca L, Babu V, Ermolaeva MA, Müller RU, Frommolt P, Williams AB, Greiss S, Schneider JI, Benzing T, Schermer B, Schumacher B
    Nat Cell Biol 2014, 16(12), 1168-79
  • Expression pattern of thyroid hormone transporters in the postnatal mouse brain.
    Müller J, Heuer H
    Front Endocrinol (Lausanne) 2014, 5, 92
  • Atypical RNAs in the coelacanth transcriptome.
    Nitsche A, Doose G, Tafer H, Robinson M, Saha NR, Gerdol M, Canapa A, Hoffmann S, Amemiya CT, Stadler PF
    J Exp Zool B Mol Dev Evol 2014, 322(6), 342-51
  • Measuring telomere length and telomere dynamics in evolutionary biology and ecology
    Nussey DH, Baird D, Barrett E, Boner W, Fairlie J, Gemmell N, Hartmann N, Horn T, Haussmann M, Olsson M, Turbill C, Verhulst S, Zahn S, Monaghan P
    Methods Ecol Evol 2014, 5(4), 299–310
  • Substantial telomere shortening in the substantia nigra of telomerase-deficient mice does not increase susceptibility to MPTP-induced dopamine depletion.
    Oeckl P, Scheffold A, Lechel A, Rudolph KL, Ferger B
    Neuroreport 2014, 25(5), 335-9 published during change of institution
  • Häm und seine Abbauprodukte
    Ohlenschläger O, Schiller A, Jahns F, Heinemann SH
    Nachr Chem 2014, 62(2), 119-24
  • The use of targeted proteomics to determine the stoichiometry of large macromolecular assemblies.
    Ori* A, Andrés-Pons* A, Beck M
    Methods Cell Biol 2014, 122, 117-46 * equal contribution
  • Lacking alignments? The next-generation sequencing mapper segemehl revisited.
    Otto C, Stadler PF, Hoffmann S
    Bioinformatics 2014, 30(13), 1837-43
  • Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits.
    Piazza I, Rutkowska A, Ori A, Walczak M, Metz J, Pelechano V, Beck M, Haering CH
    Nat Struct Mol Biol 2014, 21(6), 560-8
  • Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.
    Placke T, Faber K, Nonami A, Putwain SL, Salih HR, Heidel FH, Krämer A, Root DE, Barbie DA, Krivtsov AV, Armstrong SA, Hahn WC, Huntly BJ, Sykes SM, Milsom MD, Scholl C, Fröhling S
    Blood 2014, 124(1), 13-23
  • Inhibition of JAK-STAT signaling stimulates adult satellite cell function.
    Price* FD, von Maltzahn* J, Bentzinger CF, Dumont NA, Yin H, Chang NC, Wilson DH, Frenette J, Rudnicki MA
    Nat Med 2014, 10, 1174-81 * equal contribution, published during change of institution
  • The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons.
    Purohit P, Perez-Branguli F, Prots I, Borger E, Gunn-Moore F, Welzel O, Loy K, Wenzel EM, Grömer TW, Brachs S, Holzer M, Buslei R, Fritsch K, Regensburger M, Böhm KJ, Winner B, Mielenz D
    PLoS One 2014, 9(8), e103976
  • Graph-distance distribution of the Boltzmann ensemble of RNA secondary structures.
    Qin J, Fricke M, Marz M, Stadler PF, Backofen R
    Algorithms Mol Biol 2014, 9, 19
  • Independently recruited oxidases from the glucose-methanol-choline oxidoreductase family enabled chemical defences in leaf beetle larvae (subtribe Chrysomelina) to evolve.
    Rahfeld P, Kirsch R, Kugel S, Wielsch N, Stock M, Groth M, Boland W, Burse A
    Proc Biol Sci 2014, 281(1788), 20140842
  • The Comet-Fish technique, a tool for detection of specific DNA damage and repair
    Rapp A, Hausmann M, Greulich KO
    In: Molecular Toxicology Protocols, Methods in Molecular Biology (edited by Phouthone K, Stephen GG) 2014, 107-19, Humana Press Inc., Totow
  • A first glimpse at the genome of the Baikalian amphipod Eulimnogammarus verrucosus.
    Rivarola-Duarte L, Otto C, Jühling F, Schreiber S, Bedulina D, Jakob L, Gurkov A, Axenov-Gribanov D, Sahyoun AH, Lucassen M, Hackermüller J, Hoffmann S, Sartoris F, Pörtner HO, Timofeyev M, Luckenbach T, Stadler PF
    J Exp Zool B Mol Dev Evol 2014, 322(3), 177-89
  • Novel mechanism of JNK pathway activation by adenoviral E1A.
    Romanov* VS, Brichkina* AI, Morrison H, Pospelova TV, Pospelov VA, Herrlich P
    Oncotarget 2014, 5(8), 2176-86 * equal contribution
  • Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans.
    Sabala I, Jagielska E, Bardelang PT, Czapinska H, Dahms SO, Sharpe JA, James R, Than ME, Thomas NR, Bochtler M
    FEBS J 2014, 281(18), 4112-22
  • Evidence for the existence of two new members of the family Chlamydiaceae and proposal of Chlamydia avium sp. nov. and Chlamydia gallinacea sp. nov.
    Sachse K, Laroucau K, Riege K, Wehner S, Dilcher M, Creasy HH, Weidmann M, Myers G, Vorimore F, Vicari N, Magnino S, Liebler-Tenorio E, Ruettger A, Bavoil PM, Hufert FT, Rosselló-Móra R, Marz M
    Syst Appl Microbiol 2014, 37(2), 79-88
  • Vitamin supplementation by gut symbionts ensures metabolic homeostasis in an insect host.
    Salem H, Bauer E, Strauss AS, Vogel H, Marz M, Kaltenpoth M
    Proc Biol Sci 2014, 281(1796), 20141838
  • Miz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation.
    Sanz-Moreno A, Fuhrmann D, Wolf E, von Eyss B, Eilers M, Elsässer HP
    PLoS One 2014, 9(2), e89187
  • Germ and hematology: underlying disease influences diversity of germ spectra and antibiotic therapy.
    Schalk E, Tammer I, Heidel FH
    Infect Control Hosp Epidemiol 2014, 35(2), 208-10
  • Targeting V-ATPase in primary human monocytes by archazolid potently represses the classical secretion of cytokines due to accumulation at the endoplasmic reticulum.
    Scherer O, Steinmetz H, Kaether C, Weinigel C, Barz D, Kleinert H, Menche D, Müller R, Pergola C, Werz O
    Biochem Pharmacol 2014, 91(4), 490-500
  • Exon 11 skipping of SCN10A coding for voltage-gated sodium channels in dorsal root ganglia.
    Schirmeyer J, Szafranski K, Leipold E, Mawrin C, Platzer M, Heinemann SH
    Channels 2014, 8(3), 210 -15
  • Linear Contrast Classifiers in High-Dimensional Spaces
    Schmid F, Lausser L, Kestler HA
    In: Lecture Notes in Computer Science (edited by El G, Neamat, Schwenker, Friedhelm, Suen, Ching Y), Artificial Neural Networks in Pattern Recognition 2014, 8774, 141-52, Springer International P published during change of institution
  • Biosimilar G-CSF Based Mobilization of Peripheral Blood Hematopoietic Stem Cells for Autologous and Allogeneic Stem Cell Transplantation.
    Schmitt M, Publicover A, Orchard KH, Görlach M, Wang L, Schmitt A, Mani J, Tsirigotis P, Kuriakose R, Nagler A
    Theranostics 2014, 4(3), 280-9
  • Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial mucorales (Mucoromycotina).
    Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K
    PLoS Genet 2014, 10(8), e1004496
  • Epithelial regeneration and cancer: news from the Src front.
    Sousa-Victor P, Jasper H
    EMBO J 2014, 33(13), 1423-4
  • Integrin αvβ3 and thyroid hormones promote expansion of progenitors in embryonic neocortex.
    Stenzel D, Wilsch-Bräuninger M, Wong FK, Heuer H, Huttner WB
    Development 2014, 141(4), 795-806
  • Tissue-Specific Transcript Profiling for ABC Transporters in the Sequestering Larvae of the Phytophagous Leaf Beetle Chrysomela populi.
    Strauss AS, Wang D, Stock M, Gretscher RR, Groth M, Boland W, Burse A
    PLoS One 2014, 9(6), e98637
  • Physiological state co-regulates thousands of mammalian mRNA splicing events at tandem splice sites and alternative exons.
    Szafranski K, Fritsch C, Schumann F, Siebel L, Sinha R, Hampe J, Hiller M, Englert C, Huse K, Platzer M
    Nucleic Acids Res 2014, 42(14), 8895-904
  • DNA binding properties of human Cdc45 suggest a function as molecular wedge for DNA unwinding.
    Szambowska A, Tessmer I, Kursula P, Usskilat C, Prus P, Pospiech H, Grosse F
    Nucleic Acids Res 2014, 42(4), 2308-19
  • RelB-induced expression of Cot, a MAP3K, rescues RANKL-induced osteoclastogenesis in alymphoplasia mice by promoting NF-κB2 processing by IKKα
    Taniguchi R, Fukushima H, Osawa K, Maruyama T, Yasuda H, Weih F, Doi T, Maki K, Jimi E
    J Biol Chem 2014, 289(11), 7349-61
  • Narrowing down the distal border of the copy number variable beta-defensin gene cluster on human 8p23.
    Taudien S, Huse K, Groth M, Platzer M
    BMC Res Notes 2014, 7(1), 93
  • Regulation of microRNA expression in the neuronal stem cell niches during aging of the short-lived annual fish Nothobranchius furzeri.
    Terzibasi Tozzini E, Savino A, Ripa R, Battistoni G, Baumgart M, Cellerino A
    Front Cell Neurosci 2014, 8, 51
  • Comparative analysis of mitochondrial genomes from closely related Rhynchosporium species reveals extensive intron invasion.
    Torriani SFF, Penselin D, Knogge W, Felder M, Taudien S, Platzer M, McDonald BA, Brunner PC
    Fungal Genet Biol 2014, 62, 34-42
  • Aging stem cells: transcriptome meets epigenome meets methylome.
    Tümpel S, Rudolph KL
    Cell Stem Cell 2014, 14(5), 551-2
  • Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars.
    Uniewicz KA, Ori A, Ahmed YA, Yates EA, Fernig DG
    PeerJ 2014, 2, e461
  • Gap-directed translesion DNA synthesis of an abasic site on circular DNA templates by a human replication complex.
    Villani G, Shevelev I, Orlando E, Pospiech H, Syvaoja JE, Markkanen E, Hubscher U, Le Gac NT
    PLoS One 2014, 9(4), e93908
  • Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.
    Walz S, Lorenzin F, Morton J, Wiese KE, von Eyss B, Herold S, Rycak L, Dumay-Odelot H, Karim S, Bartkuhn M, Roels F, Wüstefeld T, Fischer M, Teichmann M, Zender L, Wei CL, Sansom O, Wolf E, Eilers M
    Nature 2014, 511(7510), 483-7
  • Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres.
    Wang J, Lu X, Sakk V, Klein CA, Rudolph KL
    Blood 2014, 124(22), 3237-40
  • Promoting longevity by maintaining metabolic and proliferative homeostasis.
    Wang L, Karpac J, Jasper H
    J Exp Biol 2014, 217(Pt 1), 109-18
  • Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation.
    Wang L, Zeng X, Ryoo HD, Jasper H
    PLoS Genet 2014, 10(8), e1004568
  • A coimmunization vaccine of Aβ42 ameliorates cognitive deficits without brain inflammation in an Alzheimer's disease model.
    Wang S, Yu Y, Geng S, Wang D, Zhang L, Xie X, Wu B, Li C, Xu H, Li X, Hu Y, Zhang L, Kaether C, Wang B
    Alzheimers Res Ther 2014, 6(3), 26
  • The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining.
    Waters CA, Strande NT, Pryor JM, Strom CN, Mieczkowski P, Burkhalter MD, Oh S, Qaqish BF, Moore DT, Hendrickson EA, Ramsden DA
    Nat Commun 2014, 5, 4286
  • Dissemination of 6S RNA among bacteria.
    Wehner S, Damm K, Hartmann RK, Marz M
    RNA Biol 2014, 11(11), 1467-78
  • pRNA: NoRC-associated RNA of rRNA operons.
    Wehner S, Dörrich AK, Ciba P, Wilde A, Marz M
    RNA Biol 2014, 11(1), 3-9
  • Detection of very long antisense transcripts by whole transcriptome RNA-Seq analysis of Listeria monocytogenes by semiconductor sequencing technology.
    Wehner S, Mannala GK, Qing X, Madhugiri R, Chakraborty T, Mraheil MA, Hain** T, Marz** M
    PLoS One 2014, 9(10), e108639 ** co-corresponding authors
  • D-Glucosamine supplementation extends life span of nematodes and of ageing mice.
    Weimer S, Priebs J, Kuhlow D, Groth M, Priebe S, Mansfeld J, Merry TL, Dubuis S, Laube B, Pfeiffer AF, Schulz TJ, Guthke R, Platzer M, Zamboni N, Zarse K, Ristow M
    Nat Commun 2014, 5, 3563
  • CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies.
    Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, Gutmann DH, Hanemann CO, Hennigan R, Huson S, Ingram D, Kissil J, Korf BR, Legius E, Packer RJ, McClatchey AI, McCormick F, North K, Pehrsson M, Plotkin SR, Ramesh V, Ratner N, Schirmer S, Sherman L, Schorry E, Stevenson D, Stewart DR, Ullrich N, Bakker AC, Morrison H
    Am J Med Genet A 2014, 164A(3), 563-78
  • Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.
    Winkler J, Ori A, Holzer K, Sticht C, Dauch D, Eiteneuer EM, Pinna F, Geffers R, Ehemann V, Andres-Pons A, Breuhahn K, Longerich T, Bermejo JL, Gretz N, Zender L, Schirmacher P, Beck M, Singer S
    Hepatology 2014, 60(3), 884-95
  • A rare cause of lower back pain.
    Wolleschak D, Heidel FH
    Blood 2014, 124(2), 165
  • Clinically relevant doses of FLT3-kinase inhibitors quizartinib and midostaurin do not impair T-cell reactivity and function.
    Wolleschak D, Mack TS, Perner F, Frey S, Schnöder TM, Wagner MC, Höding C, Pils MC, Parkner A, Kliche S, Schraven B, Hebel K, Brunner-Weinzierl M, Ranjan S, Isermann B, Lipka DB, Fischer T, Heidel FH
    Haematologica 2014, 99(6), e90-3
  • Loss of Caenorhabditis elegans BRCA1 promotes genome stability during replication in smc-5 mutants.
    Wolters S, Ermolaeva MA, Bickel JS, Fingerhut JM, Khanikar J, Chan RC, Schumacher B
    Genetics 2014, 196(4), 985-99
  • Quantitative Dissection and Modeling of the NF-κB p100-p105 Module Reveals Interdependent Precursor Proteolysis.
    Yılmaz ZB, Kofahl B, Beaudette P, Baum K, Ipenberg I, Weih F, Wolf J, Dittmar G, Scheidereit C
    Cell Rep 2014, 9(5), 1756-69
  • Exonuclease 1 is essential for maintaining genomic stability and the proliferative capacity of neural but not hematopoietic stem cells.
    Zhang J, Yang R, Zhou D, Rudolph KL, Meng A, Ju Z
    Stem Cell Res 2014, 12(1), 250-9
  • Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1.
    Zhang SC, Gremer L, Heise H, Janning P, Shymanets A, Cirstea IC, Krause E, Nürnberg B, Ahmadian MR
    PLoS One 2014, 9(7), e102425
  • 8p23 beta-defensin copy number determination by single-locus pseudogene-based paralog ratio tests risk bias due to low-frequency sequence variations.
    Zhang X, Müller S, Möller M, Huse K, Taudien S, Book M, Stuber F, Platzer M, Groth M
    BMC Genomics 2014, 15(1), 64

Publications 2013:

  • The African coelacanth genome provides insights into tetrapod evolution.
    Amemiya CT, Alföldi J, Lee AP, Fan S, Philippe H, Maccallum I, Braasch I, Manousaki T, Schneider I, Rohner N, Organ C, Chalopin D, Smith JJ, Robinson M, Dorrington RA, Gerdol M, Aken B, Biscotti MA, Barucca M, Baurain D, Berlin AM, Blatch GL, Buonocore F, Burmester T, Campbell MS, Canapa A, Cannon JP, Christoffels A, De Moro G, Edkins AL, Fan L, Fausto AM, Feiner N, Forconi M, Gamieldien J, Gnerre S, Gnirke A, Goldstone JV, Haerty W, Hahn ME, Hesse U, Hoffmann S, Johnson J, Karchner SI, Kuraku S, Lara M, Levin JZ, Litman GW, Mauceli E, Miyake T, Mueller MG, Nelson DR, Nitsche A, Olmo E, Ota T, Pallavicini A, Panji S, Picone B, Ponting CP, Prohaska SJ, Przybylski D, Saha NR, Ravi V, Ribeiro FJ, Sauka-Spengler T, Scapigliati G, Searle SMJ, Sharpe T, Simakov O, Stadler PF, Stegeman JJ, Sumiyama K, Tabbaa D, Tafer H, Turner-Maier J, van Heusden P, White S, Williams L, Yandell M, Brinkmann H, Volff JN, Tabin CJ, Shubin N, Schartl M, Jaffe DB, Postlethwait JH, Venkatesh B, Di Palma F, Lander ES, Meyer A, Lindblad-Toh K
    Nature 2013, 496(7445), 311-6
  • CD133 is a modifier of hematopoietic progenitor frequencies but is dispensable for the maintenance of mouse hematopoietic stem cells.
    Arndt K, Grinenko T, Mende N, Reichert D, Portz M, Ripich T, Carmeliet P, Corbeil D, Waskow C
    Proc Natl Acad Sci U S A 2013, 110(14), 5582-7
  • Intestinal inflammation and stem cell homeostasis in aging Drosophila melanogaster.
    Ayyaz A, Jasper H
    Front Cell Infect Microbiol 2013, 3, 98
  • Strong population genetic structuring in an annual fish, Nothobranchius furzeri, suggests multiple savannah refugia in southern Mozambique.
    Bartáková V, Reichard M, Janko K, Polačik M, Blažek R, Reichwald K, Cellerino A, Bryja J
    BMC Evol Biol 2013, 13(1), 196
  • Molecular determinants of glucocorticoid actions in inflammatory joint diseases.
    Baschant U, Culemann S, Tuckermann J
    Mol Cell Endocrinol 2013, 380(1-2), 108-18
  • The emerging biology of muscle stem cells: implications for cell-based therapies.
    Bentzinger CF, Wang YX, von Maltzahn J, Rudnicki MA
    Bioessays 2013, 35(3), 231-41
  • Fibronectin regulates Wnt7a signaling and satellite cell expansion.
    Bentzinger CF, Wang YX, von Maltzahn J, Soleimani VD, Yin H, Rudnicki MA
    Cell Stem Cell 2013, 12(1), 75-87
  • The positional identity of mouse ES cell-generated neurons is affected by BMP signaling.
    Bertacchi M, Pandolfini L, Murenu E, Viegi A, Capsoni S, Cellerino A, Messina A, Casarosa S, Cremisi F
    Cell Mol Life Sci 2013, 70(6), 1095-111
  • Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers.
    Biniossek ML, Lechel A, Rudolph KL, Martens UM, Zimmermann S
    J Proteomics 2013, 91, 515-35 published during change of institution
  • Integrated structural analysis of the human nuclear pore complex scaffold.
    Bui KH, von Appen A, DiGuilio AL, Ori A, Sparks L, Mackmull MT, Bock T, Hagen W, Andrés-Pons A, Glavy JS, Beck M
    Cell 2013, 155(6), 1233-43
  • LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys.
    Burghardt T, Kastner J, Suleiman H, Rivera-Milla E, Stepanova N, Lottaz C, Kubitza M, Böger CA, Schmidt S, Gorski M, de Vries U, Schmidt H, Hertting I, Kopp J, Rascle A, Moser M, Heid IM, Warth R, Spang R, Wegener J, Mierke CT, Englert C, Witzgall R
    J Am Soc Nephrol 2013, 24(11), 1830-48
  • Grk5l Controls Heart Development by Limiting mTOR Signaling during Symmetry Breaking.
    Burkhalter MD, Fralish GB, Premont RT, Caron MG, Philipp M
    Cell Rep 2013, 4(4), 625-32
  • Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes.
    Cirstea IC, Gremer L, Dvorsky R, Zhang SC, Piekorz RP, Zenker M, Ahmadian MR
    Hum Mol Genet 2013, 22(2), 262-70
  • Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways.
    Dang M, Armbruster N, Miller MA, Cermeno E, Hartmann M, Bell GW, Root DE, Lauffenburger DA, Lodish HF, Herrlich A
    Proc Natl Acad Sci U S A 2013, 110(24), 9776-81 Editors' Choice
  • Mapping the RNA-Seq trash bin: unusual transcripts in prokaryotic transcriptome sequencing data.
    Doose G, Alexis M, Kirsch R, Findeiß S, Langenberger D, Machné R, Mörl M, Hoffmann S, Stadler PF
    RNA Biol 2013, 10(7), 1204-10
  • Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant.
    Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KHA, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, Fukagawa T, Gassmann R, Gerlich DW, Glover DM, Gorbsky GJ, Harrison SC, Heun P, Hirota T, Jansen LET, Karpen G, Kops GJPL, Lampson MA, Lens SM, Losada A, Luger K, Maiato H, Maddox PS, Margolis RL, Masumoto H, McAinsh AD, Mellone BG, Meraldi P, Musacchio A, Oegema K, O'Neill RJ, Salmon ED, Scott KC, Straight AF, Stukenberg PT, Sullivan BA, Sullivan KF, Sunkel CE, Swedlow JR, Walczak CE, Warburton PE, Westermann S, Willard HF, Wordeman L, Yanagida M, Yen TJ, Yoda K, Cleveland DW
    Chromosome Res 2013, 21(2), 101-6
  • Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome sequencing.
    Eisenreich S, Abou-El-Ardat K, Szafranski K, Campos Valenzuela JA, Rump A, Nigro JM, Bjerkvig R, Gerlach EM, Hackmann K, Schröck E, Krex D, Kaderali L, Schackert G, Platzer M, Klink B
    PLoS One 2013, 8(9), e76623
  • The innate immune system as mediator of systemic DNA damage responses.
    Ermolaeva M, Schumacher B
    Commun Integr Biol 2013, 6(6), e26926
  • DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.
    Ermolaeva MA, Segref A, Dakhovnik A, Ou HL, Schneider JI, Utermöhlen O, Hoppe T, Schumacher B
    Nature 2013, 501(7467), 416-20
  • FOSL1 controls the assembly of endothelial cells into capillary tubes by direct repression of αv and β3 integrin transcription.
    Evellin S, Galvagni F, Zippo A, Neri F, Orlandini M, Incarnato D, Dettori D, Neubauer S, Kessler H, Wagner EF, Oliviero S
    Mol Cell Biol 2013, 33(6), 1198-209
  • Are aging biomarkers clinically relevant in oncogeriatrics?
    Falandry C, Gilson E, Rudolph KL
    Crit Rev Oncol Hematol 2013, 85(3), 257-65 published during change of institution
  • Characterization of a novel picornavirus isolate from a diseased European eel (Anguilla anguilla).
    Fichtner D, Philipps A, Groth M, Schmidt-Posthaus H, Granzow H, Dauber M, Platzer M, Bergmann SM, Schrudde D, Sauerbrei A, Zell R
    J Virol 2013, 87(19), 10895-99
  • In silico approaches and the role of ontologies in aging research.
    Fuellen G, Boerries M, Busch H, de Grey A, Hahn U, Hiller T, Hoeflich A, Jansen L, Janssens GE, Kaleta C, Meinema AC, Schäuble S, Simm A, Schofield PN, Smith B, Sühnel J, Vera J, Wagner W, Wönne EC, Wuttke D
    Rejuvenation Res 2013, 16(6), 540-6
  • Haplotypes of IL-12Rβ1 impact on the clinical phenotype of hidradenitis suppurativa.
    Giatrakos S, Huse K, Kanni T, Tzanetakou V, Kramer M, Grech I, Papadavid E, Katoulis A, Stavrianeas N, Nothnagel M, Platzer M, Bauer M, Giamarellos-Bourboulis EJ
    Cytokine 2013, 62(2), 297-301
  • The mitochondrial genome of Arctica islandica; Phylogeny and variation.
    Glöckner G, Heinze I, Platzer M, Held C, Abele D
    PLoS One 2013, 8(12), e82857
  • Absence of replicative senescence in cultured cells from the short-lived killifish Nothobranchius furzeri.
    Graf* M, Hartmann* N, Reichwald K, Englert C
    Exp Gerontol 2013, 48(1), 17-28 * equal contribution
  • What is a particle? A lesson from the photon
    Greulich KO
    In: The Nature of Light: What are Photons? V 2013, 8832, 431-7, SPIE Press, Bellingham, W
  • The role of telomeres in stem cells and cancer.
    Günes C, Rudolph KL
    Cell 2013, 152(3), 390-3
  • Role of NF-κB in Neurodegenerative Diseases
    Haenold R, Kretz A, Weih F
    In: Forum on Immunopathological Diseases and Therapeutics (edited by Benjamin B, Zouhair Atassi M) 2013, 4(2), 161-79, Begell House, Inc., Redd
  • Ein kurzlebiger Fisch als Modell für die Alternsforschung
    Hartmann N, Reichwald K, Platzer M, Englert C
    Biol Unserer Zeit 2013, 43, 87-95
  • The holocentric species Luzula elegans shows interplay between centromere and large-scale genome organization.
    Heckmann S, Macas J, Kumke K, Fuchs J, Schubert V, Ma L, Novák P, Neumann P, Taudien S, Platzer M, Houben A
    Plant J 2013, 73(4), 555-65
  • The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML.
    Heidel FH, Bullinger L, Arreba-Tutusaus P, Wang Z, Gaebel J, Hirt C, Niederwieser D, Lane SW, Döhner K, Vasioukhin V, Fischer T, Armstrong SA
    J Exp Med 2013, 210(1), 15-22
  • Defining the subcellular interface of nanoparticles by live-cell imaging.
    Hemmerich PH, von Mikecz AH
    PLoS One 2013, 8(4), e62018
  • The responsibility of the scientist. What can history teach us about how scientists should handle research that has the potential to create harm?
    Herrlich P
    EMBO Rep 2013, 14(9), 759-64
  • The pathophysiological consequences of thyroid hormone transporter deficiencies: Insights from mouse models.
    Heuer H, Visser TJ
    Bba-Gen Subjects 2013, 1830(7), 3974-8
  • Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks.
    Holdt LM, Hoffmann S, Sass K, Langenberger D, Scholz M, Krohn K, Finstermeier K, Stahringer A, Wilfert W, Beutner F, Gielen S, Schuler G, Gäbel G, Bergert H, Bechmann I, Stadler PF, Thiery J, Teupser D
    PLoS Genet 2013, 9(7), e1003588
  • The duck genome and transcriptome provide insight into an avian influenza virus reservoir species.
    Huang Y, Li Y, Burt DW, Chen H, Zhang Y, Qian W, Kim H, Gan S, Zhao Y, Li J, Yi K, Feng H, Zhu P, Li B, Liu Q, Fairley S, Magor KE, Du Z, Hu X, Goodman L, Tafer H, Vignal A, Lee T, Kim KW, Sheng Z, An Y, Searle S, Herrero J, Groenen MAM, Crooijmans RPMA, Faraut T, Cai Q, Webster RG, Aldridge JR, Warren WC, Bartschat S, Kehr S, Marz M, Stadler PF, Smith J, Kraus RHS, Zhao Y, Ren L, Fei J, Morisson M, Kaiser P, Griffin DK, Rao M, Pitel F, Wang J, Li N
    Nat Genet 2013, 45(7), 776-83
  • JenAge Ageing Factor Database - AgeFactDB
    Hühne R, Thalheim T, Sühnel J
    JenAge 2013, JenAge, version 1, URL http://ag
  • Mutation in CYP27A1 identified in family with coronary artery disease.
    Inanloorahatloo K, Zand Parsa AF, Huse K, Rasooli P, Davaran S, Platzer M, Fan JB, Amini S, Steemers F, Elahi E
    Eur J Med Genet 2013, 56(12), 655-60
  • MREdictor: a two-step dynamic interaction model that accounts for mRNA accessibility and Pumilio binding accurately predicts microRNA targets.
    Incarnato D, Neri F, Diamanti D, Oliviero S
    Nucleic Acids Res 2013, 41(18), 8421-33
  • GABAB receptor antibodies in paraneoplastic cerebellar ataxia.
    Jarius S, Steinmeyer F, Knobel A, Streitberger K, Hotter B, Horn S, Heuer H, Schreiber SJ, Wilhelm T, Trefzer U, Wildemann B, Ruprecht K
    J Neuroimmunol 2013, 256(1-2), 94-6
  • Sirtuins: Longevity focuses on NAD+.
    Jasper H
    Nat Chem Biol 2013, 9(11), 666-7
  • Misregulation of an adaptive metabolic response contributes to the age-related disruption of lipid homeostasis in Drosophila.
    Karpac J, Biteau B, Jasper H
    Cell Rep 2013, 4(6), 1250-61
  • Aging: seeking mitonuclear balance.
    Karpac J, Jasper H
    Cell 2013, 154(2), 271-3
  • Relationships between Cargo, Cell Penetrating Peptides and Cell Type for Uptake of Non-Covalent Complexes into Live Cells.
    Keller AA, Mussbach F, Breitling R, Hemmerich P, Schaefer B, Lorkowski S, Reissmann S
    Pharmaceuticals 2013, 6(2), 184-203
  • Arachidonoyl-phosphatidylcholine oscillates during the cell cycle and counteracts proliferation by suppressing Akt membrane binding.
    Koeberle A, Shindou H, Koeberle SC, Laufer SA, Shimizu T, Werz O
    Proc Natl Acad Sci U S A 2013, 110(7), 2546-51
  • Alternative 5' Untranslated Regions Are Involved in Expression Regulation of Human Heme Oxygenase-1.
    Kramer M, Sponholz C, Slaba M, Wissuwa B, Claus RA, Menzel U, Huse K, Platzer M, Bauer M
    PLoS One 2013, 8(10), e77224
  • CEBP factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein-T mice during mammary carcinogenesis.
    Kumar M, Witt B, Knippschild U, Koch S, Meena JK, Heinlein C, Weise JM, Krepulat F, Kuchenbauer F, Iben S, Rudolph KL, Deppert W, Günes C
    Int J Cancer 2013, 132(9), 2032-43 published during change of institution
  • Reassortants of the pandemic (H1N1) 2009 virus and establishment of a novel porcine H1N2 influenza virus, lineage in Germany.
    Lange J, Groth M, Schlegel M, Krumbholz A, Wieczorek K, Ulrich R, Köppen S, Schulz K, Appl D, Selbitz HJ, Sauerbrei A, Platzer M, Zell R, Dürrwald R
    Vet Microbiol 2013, 167(3-4), 345-56
  • Dicer-processed small RNAs: rules and exceptions.
    Langenberger D, Çakir MV, Hoffmann S, Stadler PF
    J Exp Zool B Mol Dev Evol 2013, 320(1), 35-46
  • The correlation of genome size and DNA methylation rate in metazoans.
    Lechner M, Marz M, Ihling C, Sinz A, Stadler PF, Krauss V
    Theor Biosci 2013, 132(1), 47-60
  • Characterization of a new class of androgen receptor antagonists with potential therapeutic application in advanced prostate cancer.
    Li H, Hassona MD, Lack NA, Axerio-Cilies P, Leblanc E, Kanaan N, Frewin K, Singh K, Adomat H, Böhm KJ, Prinz H, Guns ET, Rennie PS, Cherkasov A
    Mol Cancer Ther 2013, 12(11), 2425-35
  • Dpp signaling determines regional stem cell identity in the regenerating adult Drosophila gastrointestinal tract.
    Li H, Qi Y, Jasper H
    Cell Rep 2013, 4(1), 10-8
  • Identification of purple sea urchin telomerase RNA using a next-generation sequencing based approach.
    Li* Y, Podlevsky* JD, Marz* M, Qi X, Hoffmann S, Stadler PF, Chen JJL
    RNA 2013, 19(6), 852-60 * equal contribution
  • BSTA: a targeted approach combines bulked segregant analysis with next- generation sequencing and de novo transcriptome assembly for SNP discovery in sunflower.
    Livaja M, Wang Y, Wieckhorst S, Haseneyer G, Seidel M, Hahn V, Knapp SJ, Taudien S, Schön CC, Bauer E
    BMC Genomics 2013, 14, 628
  • Genomics-based high-resolution mapping of the BaMMV/BaYMV resistance gene rym11 in barley (Hordeum vulgare L.).
    Lüpken T, Stein N, Perovic D, Habekuß A, Krämer I, Hähnel U, Steuernagel B, Scholz U, Zhou R, Ariyadasa R, Taudien S, Platzer M, Martis M, Mayer K, Friedt W, Ordon F
    Theor Appl Genet 2013, 126(5), 1201-12
  • An investigation of the effects of the antioxidants, ebselen or N-acetyl cysteine on human peripheral blood mononuclear cells and T cells.
    Marthandan S, Hyland P, Pawelec G, Barnett Y
    Immun Ageing 2013, 10(1), 7
  • RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.
    Mills JR, Malina A, Lee T, Di Paola D, Larsson O, Miething C, Grosse F, Tang H, Zannis-Hadjopoulos M, Lowe SW, Pelletier J
    Blood 2013, 121(17), 3402-12
  • Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera.
    Mullally A, Bruedigam C, Poveromo L, Heidel FH, Purdon A, Vu T, Austin R, Heckl D, Breyfogle LJ, Kuhn CP, Kalaitzidis D, Armstrong SA, Williams DA, Hill GR, Ebert BL, Lane SW
    Blood 2013, 121(18), 3692-702
  • Distribution, functional impact, and origin mechanisms of copy number variation in the barley genome.
    Muñoz-Amatriaín M, Eichten SR, Wicker T, Richmond TA, Mascher M, Steuernagel B, Scholz U, Ariyadasa R, Spannagl M, Nussbaumer T, Mayer KF, Taudien S, Platzer M, Jeddeloh JA, Springer NM, Muehlbauer GJ, Stein N
    Genome Biol 2013, 14(6), R58
  • Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells.
    Neri F, Incarnato D, Krepelova A, Rapelli S, Pagnani A, Zecchina R, Parlato C, Oliviero S
    Genome Biol 2013, 14(8), R91
  • Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs.
    Neri* F, Krepelova* A, Incarnato D, Maldotti M, Parlato C, Galvagni F, Matarese F, Stunnenberg HG, Oliviero S
    Cell 2013, 155(1), 121-34 * equal contribution
  • Heterozygous mutations in PALB2 cause DNA replication and damage response defects.
    Nikkilä J, Parplys AC, Pylkäs K, Bose M, Huo Y, Borgmann K, Rapakko K, Nieminen P, Xia B, Pospiech* H, Winqvist* R
    Nat Commun 2013, 4, 2578 * equal contribution
  • Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines.
    Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Bui KH, Sparks L, Solis-Mezarino V, Rinner O, Bork P, Lemke EA, Beck M
    Mol Syst Biol 2013, 9, 648
  • Swimming behavior of the monotrichous bacterium Pseudomonas fluorescens SBW25.
    Ping L, Birkenbeil J, Monajembashi S
    FEMS Microbiol Ecol 2013, 86(1), 36-44
  • Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments.
    Prewitz MC, Seib FP, von Bonin M, Friedrichs J, Stißel A, Niehage C, Müller K, Anastassiadis K, Waskow C, Hoflack B, Bornhäuser M, Werner C
    Nat Methods 2013, 10(8), 788-94
  • Extension of Life Span by Impaired Glucose Metabolism in Caenorhabditis elegans Is Accompanied by Structural Rearrangements of the Transcriptomic Network.
    Priebe S, Menzel U, Zarse K, Groth M, Platzer M, Ristow M, Guthke R
    PLoS One 2013, 8(10), e77776
  • α-Synuclein Oligomers Impair Neuronal Microtubule-Kinesin Interplay.
    Prots I, Veber V, Brey S, Campioni S, Buder K, Riek R, Böhm KJ, Winner B
    J Biol Chem 2013, 288(30), 21742-54
  • The common ancestral core of vertebrate and fungal telomerase RNAs.
    Qi X, Li Y, Honda S, Hoffmann S, Marz M, Mosig A, Podlevsky JD, Stadler PF, Selker EU, Chen JJL
    Nucleic Acids Res 2013, 41(1), 450-62
  • Why soft UV-A damages DNA: An optical micromanipulation study
    Rapp A, Greulich KO
    In: Optical Trapping and Optical Micromanipulation X (edited by Dholakia K, Spalding GC), Proceedings of SPIEE 2013, 8810, 511-7, SPIE Press, Bellingham, W
  • Pan genome of the phytoplankton Emiliania underpins its global distribution.
    Read BA, Kegel J, Klute MJ, Kuo A, Lefebvre SC, Maumus F, Mayer C, Miller J, Monier A, Salamov A, Young J, Aguilar M, Claverie JM, Frickenhaus S, Gonzalez K, Herman EK, Lin YC, Napier J, Ogata H, Sarno AF, Shmutz J, Schroeder D, de Vargas C, Verret F, von Dassow P, Valentin K, Van de Peer Y, Wheeler G, Emiliania huxleyi Annotation Consortium, Dacks JB, Delwiche CF, Dyhrman ST, Glöckner G, John U, Richards T, Worden AZ, Zhang X, Grigoriev IV
    Nature 2013, 499(7457), 209-13
  • Identification of prolyl oligopeptidase as a cyclosporine-sensitive protease by screening of mouse liver extracts.
    Rentzsch A, Kahlert V, Jahreis G, Schlott B, Schutkowski M, Malešević M, Fischer G
    Biol Chem 2013, 394(8), 1057-67
  • Histone acetyltransferase cofactor trrap maintains self-renewal and restricts differentiation of embryonic stem cells.
    Sawan C, Hernandez-Vargas H, Murr R, Lopez F, Vaissière T, Ghantous AY, Cuenin C, Imbert J, Wang ZQ, Ren B, Herceg Z
    Stem Cells 2013, 31(5), 979-91
  • Conserved gene regulatory function of the carboxy-terminal domain of dictyostelid C-module-binding factor.
    Schmith A, Groth M, Ratka J, Gatz S, Spaller T, Siol O, Glöckner G, Winckler T
    Eukaryot Cell 2013, 12(3), 460-8
  • Structural RNA alignment by multi-objective optimization.
    Schnattinger T, Schöning U, Kestler HA
    Bioinformatics 2013, 29(13), 1607-13
  • PPARβ/δ governs Wnt signaling and bone turnover.
    Scholtysek C, Katzenbeisser J, Fu H, Uderhardt S, Ipseiz N, Stoll C, Zaiss MM, Stock M, Donhauser L, Böhm C, Kleyer A, Hess A, Engelke K, David JP, Djouad F, Tuckermann JP, Desvergne B, Schett G, Krönke G
    Nat Med 2013, 19(5), 608-13
  • Ciliated sensory hair cell formation and function require the F-BAR protein syndapin I and the WH2 domain-based actin nucleator Cobl.
    Schüler S, Hauptmann J, Perner B, Kessels** MM, Englert** C, Qualmann** B
    J Cell Sci 2013, 126(Pt 1), 196-208 ** co-corresponding authors
  • Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors.
    Schwitalla S, Ziegler PK, Horst D, Becker V, Kerle I, Begus-Nahrmann Y, Lechel A, Rudolph KL, Langer R, Slotta-Huspenina J, Bader FG, Prazeres da Costa O, Neurath MF, Meining A, Kirchner T, Greten FR
    Cancer Cell 2013, 23(1), 93-106 published during change of institution
  • Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice.
    Seeling M, Hillenhoff U, David JP, Schett G, Tuckermann J, Lux A, Nimmerjahn F
    Proc Natl Acad Sci U S A 2013, 110(26), 10729-34 published during change of institution
  • Putative Sugar Transporters of the Mustard Leaf Beetle Phaedon cochleariae: Their Phylogeny and Role for Nutrient Supply in Larval Defensive Glands.
    Stock M, Gretscher RR, Groth M, Eiserloh S, Boland W, Burse A
    PLoS One 2013, 8(12), e84461
  • Rule-based modeling and simulations of the inner kinetochore structure.
    Tschernyschkow S, Herda S, Gruenert G, Döring V, Görlich D, Hofmeister A, Hoischen C, Dittrich P, Diekmann S, Ibrahim B
    Prog Biophys Mol Biol 2013, 113(1), 33-45
  • Monocarboxylate transporter 8 modulates the viability and invasive capacity of human placental cells and fetoplacental growth in mice.
    Vasilopoulou E, Loubière LS, Heuer H, Trajkovic-Arsic M, Darras VM, Visser TJ, Lash GE, Whitley GS, McCabe CJ, Franklyn JA, Kilby MD, Chan SY
    PLoS One 2013, 8(6), e65402
  • Systematic analysis and evolution of 5S ribosomal DNA in metazoans.
    Vierna J, Wehner S, Höner zu Siederdissen C, Martínez-Lage A, Marz M
    Heredity 2013, 111(5), 410-21
  • Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus.
    von Kampen O, Buch S, Nothnagel M, Azocar L, Molina H, Brosch M, Erhart W, von Schönfels W, Egberts J, Seeger M, Arlt A, Balschun T, Franke A, Lerch MM, Mayerle J, Kratzer W, Boehm BO, Huse K, Schniewind B, Tiemann K, Jiang ZY, Han TQ, Mittal B, Srivastava A, Fenger M, Jørgensen T, Schirin-Sokhan R, Tönjes A, Wittenburg H, Stumvoll M, Kalthoff H, Lammert F, Tepel J, Puschel K, Becker T, Schreiber S, Platzer M, Völzke H, Krawczak M, Miquel JF, Schafmayer C, Hampe J
    Hepatology 2013, 57(6), 2407-17
  • Pax7 is critical for the normal function of satellite cells in adult skeletal muscle.
    von Maltzahn J, Jones AE, Parks RJ, Rudnicki MA
    Proc Natl Acad Sci U S A 2013, 110(41), 16474-9
  • A truncated Wnt7a retains full biological activity in skeletal muscle.
    von Maltzahn J, Zinoviev R, Chang NC, Bentzinger CF, Rudnicki MA
    Nat Commun 2013, 4, 2869 research results from former institution
  • Nilotinib shows prolonged intracellular accumulation upon pulse-exposure: a novel mechanism for induction of apoptosis in CML cells.
    Wagner MC, Dziadosz M, Melo JV, Heidel F, Fischer T, Lipka DB
    Leukemia 2013, 27(7), 1567-70
  • The role of MIZ-1 in MYC-dependent tumorigenesis.
    Wiese KE, Walz S, von Eyss B, Wolf E, Athineos D, Sansom O, Eilers M
    Cold Spring Harb Perspect Med 2013, 3(12), a014290
  • Miz1 is required to maintain autophagic flux.
    Wolf E, Gebhardt A, Kawauchi D, Walz S, von Eyss B, Wagner N, Renninger C, Krohne G, Asan E, Roussel MF, Eilers M
    Nat Commun 2013, 4, 2535
  • Rapid induction of complete molecular remission by sequential therapy with LDAC and sorafenib in FLT3-ITD-positive patients unfit for intensive treatment: two cases and review of the literature.
    Wolleschak D, Schalk E, Krogel C, Schnoeder TM, Luehr H, Jentsch-Ullrich K, Fischer T, Heidel FH
    J Hematol Oncol 2013, 6, 39
  • Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells.
    Yamamoto* R, Morita* Y, Ooehara J, Hamanaka S, Onodera M, Rudolph KL, Ema H, Nakauchi H
    Cell 2013, 154(5), 1112-26 * equal contribution
  • PARP-1 Controls Immunosuppressive Function of Regulatory T Cells by Destabilizing Foxp3.
    Zhang P, Maruyama T, Konkel JE, Abbatiello B, Zamarron B, Wang ZQ, Chen W
    PLoS One 2013, 8(8), e71590
  • PARP-1 regulates expression of TGF-β receptors in T cells.
    Zhang P, Nakatsukasa H, Tu E, Kasagi S, Cui K, Ishikawa M, Konkel JE, Maruyama T, Wei G, Abbatiello B, Wang ZQ, Zhao K, Chen W
    Blood 2013, 122(13), 2224-32

Publications 2012:

  • Comparative evaluation of the gut microbiota associated with the below- and above-ground life stages (larvae and beetles) of the forest cockchafer, Melolontha hippocastani.
    Arias-Cordero E, Ping L, Reichwald K, Delb H, Platzer M, Boland W
    PLoS One 2012, 7(12), e51557
  • Developmental gene regulation by an ancient intercellular communication system in social amoebae.
    Asghar A, Groth M, Siol O, Gaube F, Enzensperger C, Glöckner G, Winckler T
    Protist 2012, 163(1), 25-37
  • The multiple facets of glucocorticoid action in rheumatoid arthritis.
    Baschant U, Lane NE, Tuckermann J
    Nat Rev Rheumatol 2012, 8(11), 645-55
  • Age-dependent regulation of tumor-related microRNAs in the brain of the annual fish Nothobranchius furzeri.
    Baumgart M, Groth M, Priebe S, Appelt J, Guthke R, Platzer M, Cellerino A
    Mech Ageing Dev 2012, 133(5), 226-33
  • A pRNA-induced structural rearrangement triggers 6S-1 RNA release from RNA polymerase in Bacillus subtilis.
    Beckmann BM, Hoch PG, Marz M, Willkomm DK, Salas M, Hartmann RK
    EMBO J 2012, 31(7), 1727-38
  • Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.
    Begus-Nahrmann Y, Hartmann D, Kraus J, Eshraghi P, Scheffold A, Grieb M, Rasche V, Schirmacher P, Lee HW, Kestler HA, Lechel A, Rudolph KL
    J Clin Invest 2012, 122(6), 2283-8 published during change of institution
  • Fungal-Induced Cell Cycle Impairment, Chromosome Instability and Apoptosis via Differential Activation of NF-κB.
    Ben-Abdallah M, Sturny-Leclère A, Avé P, Louise A, Moyrand F, Weih F, Janbon G, Mémet S
    PLoS Pathog 2012, 8(3), e1002555
  • Precise RNAi-mediated silencing of metabolically active proteins in the defence secretions of juvenile leaf beetles.
    Bodemann RR, Rahfeld P, Stock M, Kunert M, Wielsch N, Groth M, Frick S, Boland W, Burse A
    Proc Biol Sci 2012, 279(1745), 4126-34
  • RSK2 protects mice against TNF-induced bone loss.
    Böhm C, Derer A, Axmann R, Hillienhoff U, Zaiss MM, Luther J, Zech C, Stock M, Scholtysek C, Engelke K, Hess A, Tuckermann JP, Schett G, David JP
    J Cell Sci 2012, 125(Pt 9), 2160-71
  • Synthesis and functional characterization of tridegin and its analogues: inhibitors and substrates of factor XIIIa.
    Böhm M, Kühl T, Hardes K, Coch R, Arkona C, Schlott B, Steinmetzer T, Imhof D
    ChemMedChem 2012, 7(2), 326-33
  • Cell-cycle-dependent structural transitions in the human CENP-A nucleosome in vivo.
    Bui M, Dimitriadis EK, Hoischen C, An E, Quénet D, Giebe S, Nita-Lazar A, Diekmann S, Dalal Y
    Cell 2012, 150(2), 317-26
  • Unusual combinatorial involvement of poly-A/T tracts in organizing genes and chromatin in Dictyostelium.
    Chang GS, Noegel AA, Mavrich TN, Müller R, Tomsho L, Ward E, Felder M, Jiang C, Eichinger L, Glöckner G, Schuster SC, Pugh BF
    Genome Res 2012, 22(6), 1098-106
  • Genome dynamics explain the evolution of flowering time CCT domain gene families in the Poaceae.
    Cockram J, Thiel T, Steuernagel B, Stein N, Taudien S, Bailey PC, O'Sullivan DM
    PLoS One 2012, 7(9), e45307
  • Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity.
    Creemers JWM, Choquet H, Stijnen P, Vatin V, Pigeyre M, Beckers S, Meulemans S, Than ME, Yengo L, Tauber M, Balkau B, Elliott P, Jarvelin MR, Van Hul W, Van Gaal L, Horber F, Pattou F, Froguel P, Meyre D
    Diabetes 2012, 61(2), 383-90
  • Immunolocalization of S100-like protein in the brain of an emerging model organism: Nothobranchius furzeri.
    D'Angelo L, De Girolamo P, Cellerino A, Terzibasi Tozzini E, Varricchio E, Castaldo L, Lucini C
    Microsc Res Tech 2012, 75(4), 441-47
  • Neurotrophin Trk receptors in the brain of a teleost fish, Nothobranchius furzeri.
    D'Angelo L, de Girolamo P, Cellerino A, Tozzini ET, Castaldo L, Lucini C
    Microsc Res Tech 2012, 75(1), 81-8
  • CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin.
    Dambacher S, Deng W, Hahn M, Sadic D, Fröhlich J, Nuber A, Hoischen C, Diekmann S, Leonhardt H, Schotta G
    Nucleus 2012, 3(1), 101-10
  • ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis.
    Dellago H, Khan A, Nussbacher M, Gstraunthaler A, Lämmermann I, Schosserer M, Mück C, Anrather D, Scheffold A, Ammerer G, Jansen-Dürr P, Rudolph KL, Voglauer-Grillari R, Grillari J
    Aging (Albany NY) 2012, 4(4), 290-304 published during change of institution
  • Transcriptional Repression of ATF4 Gene by CCAAT/Enhancer-binding Protein β (C/EBPβ) Differentially Regulates Integrated Stress Response.
    Dey S, Savant S, Teske BF, Hatzoglou M, Calkhoven CF, Wek RC
    J Biol Chem 2012, 287(26), 21936-49
  • Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting.
    Fritsch C, Herrmann A, Nothnagel M, Szafranski K, Huse K, Schumann F, Schreiber S, Platzer M, Krawczak M, Hampe J, Brosch M
    Genome Res 2012, 22(11), 2208-18
  • Systems biology and bioinformatics in aging research: a workshop report.
    Fuellen G, Dengjel J, Hoeflich A, Hoeijemakers J, Kestler HA, Kowald A, Priebe S, Rebholz-Schuhmann D, Schmeck B, Schmitz U, Stolzing A, Sühnel J, Wuttke D, Vera J
    Rejuvenation Res 2012, 15(6), 631-41
  • A novel role of human holiday junction resolvase GEN1 in the maintenance of centrosome integrity.
    Gao M, Rendtlew Danielsen J, Wei LZ, Zhou DP, Xu Q, Li MM, Wang ZQ, Tong WM, Yang YG
    PLoS One 2012, 7(11), e49687
  • Contribution of the C-terminal regions of promyelocytic leukemia protein (PML) isoforms II and V to PML nuclear body formation.
    Geng Y, Monajembashi S, Shao A, Cui D, He W, Chen Z, Hemmerich** P, Tang** J
    J Biol Chem 2012, 287(36), 30729-42 ** co-senior authors
  • Autophagy researchers
    González-Estévez C
    Autophagy 2012, 8(10), 1411-14
  • Decreased neoblast progeny and increased cell death during starvation-induced planarian degrowth.
    González-Estévez C, Felix DA, Rodríguez-Esteban G, Aboobaker AA
    Int J Dev Biol 2012, 56(1-3), 83-91
  • SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians.
    González-Estévez C, Felix DA, Smith MD, Paps J, Morley SJ, James V, Sharp TV, Aboobaker AA
    PLoS Genet 2012, 8(3), e1002619
  • UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages.
    Greinert R, Volkmer B, Henning S, Breitbart EW, Greulich KO, Cardoso MC, Rapp A
    Nucleic Acids Res 2012, 40(20), 10263-73
  • Single DNA Molecule Typing, Heart Beating, DNA Repair and Ageing: The Contribution of Fluorescence Techniques
    Greulich KO, Grigaravicius P, Monajembashi S
    In: Reviews in Fluorescence 2012, Volume 2010, 199-222, Springer, Heidelberg
  • Colony-stimulating factor-1 mediates macrophage-related neural damage in a model for Charcot-Marie-Tooth disease type 1X.
    Groh J, Weis J, Zieger H, Stanley ER, Heuer H, Martini R
    Brain 2012, 135(1), 88-104
  • Telomere dysfunction puts the brakes on oncogene-induced cancers.
    Günes C, Rudolph KL
    EMBO J 2012, 31(13), 2833-4
  • The actin nucleator Cobl is crucial for Purkinje cell development and works in close conjunction with the F-actin binding protein Abp1.
    Haag N, Schwintzer L, Ahuja R, Koch N, Grimm J, Heuer H, Qualmann B, Kessels MM
    J Neurosci 2012, 32(49), 17842-56
  • Trafficking and proteolytic processing of APP.
    Haass C, Kaether C, Thinakaran G, Sisodia S
    Cold Spring Harb Perspect Med 2012, 2(5), a006270
  • Magnetic resonance imaging of the mouse visual pathway for in vivo studies of degeneration and regeneration in the CNS.
    Haenold R, Herrmann KH, Schmidt S, Reichenbach JR, Schmidt KF, Löwel S, Witte OW, Weih F, Kretz A
    Neuroimage 2012, 59(1), 363-76
  • Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis.
    Hamidi T, Algül H, Cano CE, Sandi MJ, Molejon MI, Riemann M, Calvo EL, Lomberk G, Dagorn JC, Weih F, Urrutia R, Schmid RM, Iovanna JL
    J Clin Invest 2012, 122(6), 2092-103
  • A microinjection protocol for the generation of transgenic killifish (Species: Nothobranchius furzeri).
    Hartmann N, Englert C
    Dev Dyn 2012, 241(6), 1133-41
  • Genetic and pharmacologic inhibition of β-catenin targets imatinib-resistant leukemia stem cells in CML.
    Heidel FH, Bullinger L, Feng Z, Wang Z, Neff TA, Stein L, Kalaitzidis D, Lane SW, Armstrong SA
    Cell Stem Cell 2012, 10(4), 412-24
  • Possibilities and limitations for high resolution small animal MRI on a clinical whole-body 3T scanner.
    Herrmann KH, Schmidt S, Kretz A, Haenold R, Krumbein I, Metzler M, Gaser C, Witte OW, Reichenbach JR
    MAGMA 2012, 25(3), 233-44
  • Niche science: the aging stem cell.
    Jasper H, Kennedy BK
    Cell Cycle 2012, 11(16), 2959-60
  • Neurofibromatosis 2011: a report of the Children's Tumor Foundation Annual Meeting.
    Kalamarides M, Acosta MT, Babovic-Vuksanovic D, Carpen O, Cichowski K, Gareth Evans D, Giancotti F, Oliver Hanemann C, Ingram D, Lloyd AC, Mayes DA, Messiaen L, Morrison H, North K, Packer R, Pan D, Stemmer-Rachamimov A, Upadhyaya M, Viskochil D, Wallace MR, Hunter-Schaedle K, Ratner N
    Acta Neuropathol (Berl) 2012, 123(3), 369-80
  • Notch-mediated suppression of TSC2 expression regulates cell differentiation in the Drosophila intestinal stem cell lineage.
    Kapuria S, Karpac J, Biteau B, Hwangbo D, Jasper H
    PLoS Genet 2012, 8(11), e1003045
  • Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation.
    Katz SF, Lechel A, Obenauf AC, Begus-Nahrmann Y, Kraus JM, Hoffmann EM, Duda J, Eshraghi P, Hartmann D, Liss B, Schirmacher P, Kestler HA, Speicher MR, Rudolph KL
    Gastroenterology 2012, 142(5), 1229-1239.e3 published during change of institution
  • Functionality, growth and accelerated aging of tissue engineered living autologous vascular grafts.
    Kelm JM, Emmert MY, Zürcher A, Schmidt D, Begus Nahrmann Y, Rudolph KL, Weber B, Brokopp CE, Frauenfelder T, Leschka S, Odermatt B, Jenni R, Falk V, Zünd G, Hoerstrup SP
    Biomaterials 2012, 33(33), 8277-85 published during change of institution
  • Schnurri regulates hemocyte function to promote tissue recovery after DNA damage.
    Kelsey EM, Luo X, Brückner K, Jasper H
    J Cell Sci 2012, 125(Pt 6), 1393-400
  • Malfunctioning DNA Damage Response (DDR) Leads to the Degeneration of Nigro-Striatal Pathway in Mouse Brain.
    Kirshner M, Galron R, Frenkel D, Mandelbaum G, Shiloh Y, Wang ZQ, Barzilai A
    J Mol Neurosci 2012, 46(3), 554-68
  • Increased reprogramming capacity of mouse liver progenitor cells, compared with differentiated liver cells, requires the BAF complex.
    Kleger A, Mahaddalkar PU, Katz SF, Lechel A, Joo JY, Loya K, Lin Q, Hartmann D, Liebau S, Kraus JM, Cantz T, Kestler HA, Zaehres H, Schöler H, Rudolph KL
    Gastroenterology 2012, 142(4), 907-17 published during change of institution
  • Liver X receptors orchestrate osteoblast/osteoclast crosstalk and counteract pathologic bone loss.
    Kleyer A, Scholtysek C, Bottesch E, Hillienhof U, Beyer C, Distler JH, Tuckermann JP, Schett G, Krönke G
    J Bone Miner Res 2012, 27(12), 2442-51
  • Guidelines for the use and interpretation of assays for monitoring autophagy.
    Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NYO, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ETW, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LAM, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RCC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SSL, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CHK, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AMK, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RSB, Clarke PGH, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CAM, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LMD, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S
    Autophagy 2012, 8(4), 445-544
  • Guidelines for the use and interpretation of assays for monitoring autophagy.
    Klionsky DJ, Abdalla FC, other participants, González-Estévez C, other participants, Zuckerbraun B
    Autophagy 2012, 8(4), 445-544
  • Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.
    Koeberle SC, Romir J, Fischer S, Koeberle A, Schattel V, Albrecht W, Grütter C, Werz O, Rauh D, Stehle T, Laufer SA
    Nat Chem Biol 2012, 8(2), 141-3
  • Proteomic identification of PSF and p54(nrb) as TopBP1-interacting proteins.
    Kuhnert A, Schmidt U, Monajembashi S, Franke C, Schlott B, Grosse F, Greulich KO, Saluz HP, Hänel F
    J Cell Biochem 2012, 113(5), 1744-53
  • deepBlockAlign: a tool for aligning RNA-seq profiles of read block patterns.
    Langenberger D, Pundhir S, Ekstrøm CT, Stadler PF, Hoffmann S, Gorodkin J
    Bioinformatics 2012, 28(1), 17-24
  • Cell-type, dose, and mutation-type specificity dictate mutant p53 functions in vivo.
    Lee MK, Teoh WW, Phang BH, Tong WM, Wang ZQ, Sabapathy K
    Cancer Cell 2012, 22(6), 751-64
  • A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons.
    Li R, Yang YG, Gao Y, Wang ZQ, Tong WM
    Cell Res 2012, 22(5), 859-72
  • Molecular, phylogenetic and comparative genomic analysis of the cytokinin oxidase/dehydrogenase gene family in the Poaceae.
    Mameaux S, Cockram J, Thiel T, Steuernagel B, Stein N, Taudien S, Jack P, Werner P, Gray JC, Greenland AJ, Powell W
    Plant Biotechnol J 2012, 10(1), 67-82
  • Telomere length, telomerase activity and osteogenic differentiation are maintained in adipose-derived stromal cells from senile osteoporotic SAMP6 mice.
    Mirsaidi A, Kleinhans KN, Rimann M, Tiaden AN, Stauber M, Rudolph KL, Richards PJ
    J Tissue Eng Regen M 2012, 6(5), 378-90 published during change of institution
  • Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development.
    Mueller KM, Themanns M, Friedbichler K, Kornfeld JW, Esterbauer H, Tuckermann JP, Moriggl R
    Mol Cell Endocrinol 2012, 361(1-2), 1-11
  • Multi-Objective Parameter Selection for Classifiers
    Müssel C, Lausser L, Maucher M, Kestler HA
    J Stat Softw 2012, 46(5), 1–27
  • Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells.
    Neri F, Zippo A, Krepelova A, Cherubini A, Rocchigiani M, Oliviero S
    Mol Cell Biol 2012, 32(4), 840-51
  • Fast and sensitive mapping of bisulfite-treated sequencing data.
    Otto C, Stadler PF, Hoffmann S
    Bioinformatics 2012, 28(13), 1698-704
  • Isolation and molecular characterization of a second serotype of the encephalomyocarditis virus.
    Philipps A, Dauber M, Groth M, Schirrmeier H, Platzer M, Krumbholz A, Wutzler P, Zell R
    Vet Microbiol 2012, 161(1-2), 49-57
  • Coevolution of aah: a dps-like gene with the host bacterium revealed by comparative genomic analysis.
    Ping L, Platzer M, Wen G, Delaroque N
    SCI WORLD J 2012, 2012, 504905
  • The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing.
    Rashmi RN, Eckes B, Glöckner G, Groth M, Neumann S, Gloy J, Sellin L, Walz G, Schneider M, Karakesisoglou I, Eichinger L, Noegel AA
    Nucleus 2012, 3(2), 172-86
  • Glucocorticoids Enhance Intestinal Glucose Uptake Via the Dimerized Glucocorticoid Receptor in Enterocytes.
    Reichardt SD, Föller M, Rexhepaj R, Pathare G, Minnich K, Tuckermann JP, Lang F, Reichardt HM
    Endocrinology 2012, 153(4), 1783-94
  • Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing.
    Richter J, Schlesner M, Hoffmann S, Kreuz M, Leich E, Burkhardt B, Rosolowski M, Ammerpohl O, Wagener R, Bernhart SH, Lenze D, Szczepanowski M, Paulsen M, Lipinski S, Russell RB, Adam-Klages S, Apic G, Claviez A, Hasenclever D, Hovestadt V, Hornig N, Korbel JO, Kube D, Langenberger D, Lawerenz C, Lisfeld J, Meyer K, Picelli S, Pischimarov J, Radlwimmer B, Rausch T, Rohde M, Schilhabel M, Scholtysik R, Spang R, Trautmann H, Zenz T, Borkhardt A, Drexler HG, Möller P, MacLeod RAF, Pott C, Schreiber S, Trümper L, Loeffler M, Stadler PF, Lichter P, Eils R, Küppers R, Hummel M, Klapper W, Rosenstiel P, Rosenwald A, Brors B, Siebert R, ICGC MMML-Seq Project
    Nat Genet 2012, 44(12), 1316-20
  • Advances in Stem Cell Aging
    Rudolph KL (ed)
    Book series: lse Kröner-Fresenius Symposia 2012, 3, Karger Verlag, Basel, Switzerlan
  • Connexin45 is expressed in vascular smooth muscle but its function remains elusive.
    Schmidt VJ, Jobs A, von Maltzahn J, Wörsdörfer P, Willecke K, de Wit C
    PLoS One 2012, 7(7), e42287
  • Genome-wide transcriptome analysis of the plant pathogen Xanthomonas identifies sRNAs with putative virulence functions.
    Schmidtke C, Findeiss S, Sharma CM, Kuhfuss J, Hoffmann S, Vogel J, Stadler PF, Bonas U
    Nucleic Acids Res 2012, 40(5), 2020-31
  • Pharmacological estrogen administration causes a FSH-independent osteo-anabolic effect requiring ER alpha in osteoblasts.
    Seitz S, Keller J, Schilling AF, Jeschke A, Marshall RP, Stride BD, Wintermantel T, Beil FT, Amling M, Schütz G, Tuckermann** J, Schinke** T
    PLoS One 2012, 7(11), e50301 ** co-corresponding authors
  • Accumulation of p100, a Precursor of NF-κB2, Enhances Osteoblastic Differentiation in Vitro and Bone Formation in Vivo in aly/aly Mice.
    Seo Y, Fukushima H, Maruyama T, Kuroishi KN, Osawa K, Nagano K, Aoki K, Weih F, Doi T, Zhang M, Ohya K, Katagiri T, Hosokawa R, Jimi E
    Mol Endocrinol 2012, 26(3), 414-22
  • Telomere dysfunctional environment induces loss of quiescence and inherent impairments of hematopoietic stem cell function.
    Song Z, Zhang J, Ju Z, Rudolph KL
    Aging Cell 2012, 11(3), 449-55 published during change of institution
  • DNA damage checkpoints in stem cells, ageing and cancer.
    Sperka T, Wang J, Rudolph KL
    Nat Rev Mol Cell Biol 2012, 13(9), 579-90 published during change of institution
  • Gene polymorphisms in the heme degradation pathway and outcome of severe human sepsis.
    Sponholz C, Huse K, Kramer M, Giamarellos-Bourboulis EJ, Claus RA, Kern A, Engel C, Kuhnt E, Kiehntopf M, Routsi C, Mylona V, Tsangaris I, Heinemann SH, Reinhart K, Platzer M, Bauer M
    Shock 2012, 38(5), 459-65
  • Two novel germline KRAS mutations: expanding the molecular and clinical phenotype.
    Stark Z, Gillessen-Kaesbach G, Ryan MM, Cirstea IC, Gremer L, Ahmadian MR, Savarirayan R, Zenker M
    Clin Genet 2012, 81(6), 590-4
  • Disrupted-in-Schizophrenia 1 (DISC1) is necessary for the correct migration of cortical interneurons.
    Steinecke A, Gampe C, Valkova C, Kaether C, Bolz J
    J Neurosci 2012, 32(2), 738-45
  • Kcnh1 voltage-gated potassium channels are essential for early zebrafish development.
    Stengel* R, Rivera-Milla* E, Sahoo N, Ebert C, Bollig F, Heinemann SH, Schönherr R, Englert C
    J Biol Chem 2012, 287(42), 35565-75 * equal contribution
  • Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis.
    Taudien* S, Gäbel* G, Kuss* O, Groth M, Grützmann R, Huse K, Kluttig A, Wolf A, Nothnagel M, Rosenstiel P, Greiser KH, Werdan K, Krawczak M, Pilarsky C, Platzer M
    BMC Res Notes 2012, 5, 629 * equal contribution
  • A physical, genetic and functional sequence assembly of the barley genome.
    The International Barley Genome Sequencing Consortium, Principal investigators, Mayer KFX, Waugh R, Langridge P, Close TJ, Wise RP, Graner A, Matsumoto T, Sato K, Schulman A, Muehlbauer GJ, Stein N, Physical map construction and direct anchoring, Ariyadasa R, Schulte D, Poursarebani N, Zhou R, Steuernagel B, Mascher M, Scholz U, Shi B, Langridge P, Madishetty K, Svensson JT, Bhat P, Moscou M, Resnik J, Close TJ, Muehlbauer GJ, Hedley P, Liu H, Morris J, Waugh R, Frenkel Z, Korol A, Bergès H, Graner A, Stein N, Genomic sequencing and assembly, Steuernagel B, Scholz U, Taudien S, Felder M, Groth M, Platzer M, Stein N, BAC sequencing and assembly, Steuernagel B, Scholz U, Himmelbach A, Taudien S, Felder M, Platzer M, Lonardi S, Duma D, Alpert M, Cordero F, Beccuti M, Ciardo G, Ma Y, Wanamaker S, Close TJ, Stein N, BAC-end sequencing, Cattonaro F, Vendramin V, Scalabrin S, Radovic S, Wing R, Schulte D, Steuernagel B, Morgante M, Stein N, Waugh R, Integration of physical/genetic map and sequence resources, Nussbaumer T, Gundlach H, Martis M, Ariyadasa R, Poursarebani N, Steuernagel B, Scholz U, Wise RP, Poland J, Stein N, Mayer KFX, Gene annotation, Spannagl M, Pfeifer M, Gundlach H, Mayer KFX, Repetitive DNA analysis, Gundlach H, Moisy C, Tanskanen J, Scalabrin S, Zuccolo A, Vendramin V, Morgante M, Mayer KFX, Schulman A, Transcriptome sequencing and analysis, Pfeifer M, Spannagl M, Hedley P, Morris J, Russell J, Druka A, Marshall D, Bayer M, Swarbreck D, Sampath D, Ayling S, Febrer M, Caccamo M, Matsumoto T, Tanaka T, Sato K, Wise RP, Close TJ, Wannamaker S, Muehlbauer GJ, Stein N, Mayer KFX, Waugh R, Re-sequencing and diversity analysis, Steuernagel B, Schmutzer T, Mascher M, Scholz U, Taudien S, Platzer M, Sato K, Marshall D, Bayer M, Waugh R, Stein N, Writing and editing of the manuscript, Mayer KFX, Waugh R, Brown JWS, Schulman A, Langridge P, Platzer M, Fincher GB, Muehlbauer GJ, Sato K, Close TJ, Wise RP, Stein N
    Nature 2012, 491(7426), 711-16
  • Selective glucocorticoid receptor modulation maintains bone mineral density in mice.
    Thiele S, Ziegler N, Tsourdi E, De Bosscher K, Tuckermann JP, Hofbauer LC, Rauner M
    J Bone Miner Res 2012, 27(11), 2242-50
  • VEGFR-3 is expressed on megakaryocyte precursors in the murine bone marrow and plays a regulatory role in megakaryopoiesis.
    Thiele W, Krishnan J, Rothley M, Weih D, Plaumann D, Kuch V, Quagliata L, Weich HA, Sleeman JP
    Blood 2012, 120(9), 1899-907
  • Adult neurogenesis in the short-lived teleost Nothobranchius furzeri: localization of neurogenic niches, molecular characterization and effects of aging.
    Tozzini ET, Baumgart M, Battistoni G, Cellerino A
    Aging Cell 2012, 11(2), 241-51 evaluated by "Faculty of 1000"
  • The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems.
    Tümpel S, Rudolph KL
    Ann N Y Acad Sci 2012, 1266, 28-39 published during change of institution
  • Telomere shortening is associated with reduced duodenal HCOFormula secretory but normal gastric acid secretory capacity in aging mice.
    Tuo B, Ju Z, Riederer B, Engelhardt R, Manns MP, Rudolph KL, Seidler U
    Am J Physiol Gastrointest Liver Physiol 2012, 303(12), G1312-21 published during change of institution
  • Following protein-glycosaminoglycan polysaccharide interactions with differential scanning fluorimetry.
    Uniewicz KA, Ori A, Rudd TR, Guerrini M, Wilkinson MC, Fernig DG, Yates EA
    Methods Mol Biol 2012, 836, 171-82
  • Segregation of replicative DNA polymerases during S phase: DNA polymerase ε, but not DNA polymerases α/δ, are associated with lamins throughout S phase in human cells.
    Vaara M, Itkonen H, Hillukkala T, Liu Z, Nasheuer HP, Schaarschmidt D, Pospiech H, Syväoja JE
    J Biol Chem 2012, 287(40), 33327-38
  • Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation.
    Vandevyver S, Dejager L, Van Bogaert T, Kleyman A, Liu Y, Tuckermann J, Libert C
    J Clin Invest 2012, 122(6), 2130-40 published during change of institution
  • The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.
    von Eyss B, Maaskola J, Memczak S, Möllmann K, Schuetz A, Loddenkemper C, Tanh MD, Otto A, Muegge K, Heinemann U, Rajewsky N, Ziebold U
    EMBO J 2012, 31(4), 972-85
  • Wnt7a-Fzd7 signalling directly activates the Akt/mTOR anabolic growth pathway in skeletal muscle.
    von Maltzahn J, Bentzinger CF, Rudnicki MA
    Nat Cell Biol 2012, 14(2), 186-91
  • Wnt signaling in myogenesis.
    von Maltzahn J, Chang NC, Bentzinger CF, Rudnicki MA
    Trends Cell Biol 2012, 22(11), 602-9
  • Wnt7a treatment ameliorates muscular dystrophy.
    von Maltzahn J, Renaud JM, Parise G, Rudnicki MA
    Proc Natl Acad Sci U S A 2012, 109(50), 20614-9
  • A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage.
    Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wuestefeld T, Dauch D, Schrezenmeier H, Hofmann WK, Nakauchi H, Ju Z, Kestler HA, Zender L, Rudolph KL
    Cell 2012, 148(5), 1001-14 published during change of institution
  • Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease.
    Watabe-Rudolph M, Song Z, Lausser L, Schnack C, Begus-Nahrmann Y, Scheithauer MO, Rettinger G, Otto M, Tumani H, Thal DR, Attems J, Jellinger KA, Kestler HA, von Arnim CAF, Rudolph KL
    Neurology 2012, 78(8), 569-77 published during change of institution
  • A cell autonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure.
    Watson ML, Baehr LM, Reichardt HM, Tuckermann JP, Bodine SC, Furlow JD
    Am J Physiol Endocrinol Metab 2012, 302(10), E1210-20
  • Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia.
    Weber M, Lambeck S, Ding N, Henken S, Kohl M, Deigner HP, Enot DP, Igwe EI, Frappart L, Kiehntopf M, Claus RA, Kamradt T, Weih D, Vodovotz Y, Briles DE, Ogunniyi AD, Paton JC, Maus UA, Bauer M
    FASEB J 2012, 26(6), 2424-36
  • CD44 Promotes Intoxication by the Clostridial Iota-Family Toxins.
    Wigelsworth DJ, Ruthel G, Schnell L, Herrlich P, Blonder J, Veenstra TD, Carman RJ, Wilkins TD, Van Nhieu GT, Pauillac S, Gibert M, Sauvonnet N, Stiles BG, Popoff MR, Barth H
    PLoS One 2012, 7(12), e51356
  • Comparative evaluation of establishing a human gut microbial community within rodent models.
    Wos-Oxley M, Bleich A, Oxley APA, Kahl S, Janus L, Smoczek A, Nahrstedt H, Pils M, Taudien S, Platzer M, Hedrich HJ, Medina E, Pieper D
    Gut Microbes 2012, 3(3), 234-49
  • Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity.
    Xu R, Ori A, Rudd TR, Uniewicz KA, Ahmed YA, Guimond SE, Skidmore MA, Siligardi G, Yates EA, Fernig DG
    J Biol Chem 2012, 287(47), 40061-73
  • Sequencing of 21 varicella-zoster virus genomes reveals two novel genotypes and evidence of recombination.
    Zell R, Taudien S, Pfaff F, Wutzler P, Platzer M, Sauerbrei A
    J Virol 2012, 86(3), 1608-22

Publications 2011:

  • Laser microbeam - kinetic studies combined with molecule - structures reveal mechanisms of DNA repair
    Altenberg B, Greulich KO
    In: Optical Trapping and Optical Micromanipulation VIII, From Bio-Molecules to Tissue Studies (edited by Dholakia K, Spalding GC), Proceedings of SPIEE 2011, 8097, 80970D, SPIE Press, Bellingham,
  • Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells.
    Azukizawa H, Döhler A, Kanazawa N, Nayak A, Lipp M, Malissen B, Autenrieth I, Katayama I, Riemann M, Weih F, Berberich-Siebelt F, Lutz MB
    Eur J Immunol 2011, 41(5), 1420-34
  • The quantitative proteome of a human cell line.
    Beck M, Schmidt A, Malmstroem J, Claassen M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J, Aebersold R
    Mol Syst Biol 2011, 7, 549
  • NF-kappaB signaling and lymphoid tissue organogenesis.
    Benezech C, Mader E, Weih F, Caamano J
    In: Developmental Biology of Peripheral Lymphoid Organs (edited by Balogh P) 2011, 25-38, Springer, Heidelberg
  • Maintaining tissue homeostasis: dynamic control of somatic stem cell activity.
    Biteau B, Hochmuth CE, Jasper H
    Cell Stem Cell 2011, 9(5), 402-11
  • EGF signaling regulates the proliferation of intestinal stem cells in Drosophila.
    Biteau B, Jasper H
    Development 2011, 138(6), 1045-55
  • Regulation of Drosophila lifespan by JNK signaling.
    Biteau B, Karpac J, Hwangbo D, Jasper H
    Exp Gerontol 2011, 46(5), 349-54
  • The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation.
    Bonnet MC, Preukschat D, Welz PS, van Loo G, Ermolaeva MA, Bloch W, Haase I, Pasparakis M
    Immunity 2011, 35(4), 572-82
  • Influence of the HLA-DRB1 genotype on antibody development to interferon beta in multiple sclerosis.
    Buck D, Cepok S, Hoffmann S, Grummel V, Jochim A, Berthele A, Hartung HP, Wassmuth R, Hemmer B
    Arch Neurol 2011, 68(4), 480-7
  • Structure-function relationship in an archaebacterial methionine sulphoxide reductase B.
    Carella M, Becher J, Ohlenschläger O, Ramachandran R, Gührs KH, Wellenreuther G, Meyer-Klaucke W, Heinemann SH, Görlach M
    Mol Microbiol 2011, 79(2), 342-58
  • Retinoids Stimulate Periosteal Bone Resorption by Enhancing the Protein RANKL, a Response Inhibited by Monomeric Glucocorticoid Receptor.
    Conaway HH, Pirhayati A, Persson E, Pettersson U, Svensson O, Lindholm C, Henning P, Tuckermann J, Lerner UH
    J Biol Chem 2011, 286(36), 31425-36
  • Investigation of the functional link between ATM and NBS1 in the DNA damage response in the mouse cerebellum.
    Dar I, Yosha G, Elfassy R, Galron R, Wang ZQ, Shiloh Y, Barzilai A
    J Biol Chem 2011, 286(17), 15361-76
  • Peroxiredoxin stabilization of DE-cadherin promotes primordial germ cell adhesion.
    DeGennaro M, Hurd TR, Siekhaus DE, Biteau B, Jasper H, Lehmann R
    Dev Cell 2011, 20(2), 233-43
  • The short-lived annual fish Nothobranchius furzeri shows a typical teleost aging process reinforced by high incidence of age-dependent neoplasias.
    Di Cicco E, Tozzini Terzibasi E, Rossi G, Cellerino A
    Exp Gerontol 2011, 46(4), 249-56
  • Microscopic Techniques.
    Diekmann S
    In: An Introduction to Molecular Biotechnology, Fundamentals, Methods and Applications (edited by Wink M) 2011, 197-209, Wiley-VCH Verlagsgesell
  • Identification of adult nephron progenitors capable of kidney regeneration in zebrafish.
    Diep CQ, Ma D, Deo RC, Holm TM, Naylor RW, Arora N, Wingert RA, Bollig F, Djordjevic G, Lichman B, Zhu H, Ikenaga T, Ono F, Englert C, Cowan CA, Hukriede NA, Handin RI, Davidson AJ
    Nature 2011, 470(7332), 95-100
  • Specific amino acids in the BAR domain allow homodimerization and prevent heterodimerization of sorting nexin 33.
    Dislich B, Than ME, Lichtenthaler SF
    Biochem J 2011, 433(1), 75-83
  • Molecular and biochemical properties of the S-layer protein from the wine bacterium Lactobacillus hilgardii B706.
    Dohm N, Petri A, Schlander M, Schlott B, König H, Claus H
    Arch Microbiol 2011, 193(4), 251-61
  • Lineage-specific pleiotropy in immune aging.
    Eshraghi P, Rudolph KL
    Blood 2011, 117(12), 3250-1
  • DARIO: a ncRNA detection and analysis tool for next-generation sequencing experiments.
    Fasold M, Langenberger D, Binder H, Stadler PF, Hoffmann S
    Nucleic Acids Res 2011, 39(Web Server issue), W112-7
  • Traces of post-transcriptional RNA modifications in deep sequencing data.
    Findeiss S, Langenberger D, Stadler PF, Hoffmann S
    Biol Chem 2011, 392(4), 305-13
  • Bioinformatics in aging research: a workshop report.
    Fuellen G, Adjaye J, de Grey A, Lepperdinger G, de Magalhães JP, Sühnel J, Wipat A
    Rejuvenation Res 2011, 13(6), 763-7
  • Requirement for DNA ligase IV during embryonic neuronal development.
    Gatz SA, Ju L, Gruber R, Hoffmann E, Carr AM, Wang ZQ, Liu C, Jeggo PA
    J Neurosci 2011, 31(27), 10088-100
  • Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders.
    Gremer* L, Merbitz-Zahradnik* T, Dvorsky* R, Cirstea* IC, Kratz CP, Zenker M, Wittinghofer A, Ahmadian MR
    Hum Mutat 2011, 32(1), 33-43 * equal contribution
  • Understanding the masses of elementary particles: a step towards understanding the massless photon?
    Greulich KO
    In: The Nature of Light: What are Photons? IV, Revisiting Derivations and QM Concepts II (edited by Roychoudhuri C, Kracklauer AF, Khrennikov Andrei Yu), Proceedings of SPIEE 2011, 8121, 81210H, SPIE Press, Bellingham,
  • Why does the wave particle dualism appear to become evident particularly at optical wavelengths
    Greulich KO
    In: The Nature of Light: What are Photons? IV, Superposition and Interaction Process Models I (edited by Roychoudhuri C, Kracklauer AF, Khrennikov Andrei Yu), Proceedings of SPIEE 2011, 8121, 812116, SPIE Press, Bellingham,
  • The birth of a photon
    Greulich KO
    In: The Nature of Light: What are Photons? IV, Diverse Photon Models I (edited by Roychoudhuri C, Kracklauer AF, Khrennikov Andrei Yu), Proceedings of SPIEE 2011, 8121, 81210T, SPIE Press, Bellingham,
  • Photons bring light into DNA repair: the comet assay and laser microbeams for studying photogenotoxicity of drugs and ageing.
    Greulich KO
    J Biophotonics 2011, 4(3), 165-71
  • The GAPs between hepatocellular carcinoma and RAS.
    Guachalla LM, Rudolph KL
    J Hepatol 2011, 54(2), 191-2
  • Telomerase gene mutations are associated with cirrhosis formation.
    Hartmann D, Srivastava U, Thaler M, Kleinhans KN, N'kontchou G, Scheffold A, Bauer K, Kratzer RF, Kloos N, Katz SF, Song Z, Begus-Nahrmann Y, Kleger A, von Figura G, Strnad P, Lechel A, Günes C, Potthoff A, Deterding K, Wedemeyer H, Ju Z, Song G, Xiao F, Gillen S, Schrezenmeier H, Mertens T, Ziol M, Friess H, Jarek M, Manns MP, Beaugrand M, Rudolph KL
    Hepatology 2011, 53(5), 1608-17
  • From RNA-seq to large-scale genotyping - genomics resources for rye (Secale cereale L.).
    Haseneyer G, Schmutzer T, Seidel M, Zhou R, Mascher M, Schön CC, Taudien S, Scholz U, Stein N, Mayer KF, Bauer E
    BMC Plant Biol 2011, 11, 131
  • Cellular distribution of metastasis suppressor 1 and the shape of cell bodies are temporarily altered in Engrailed-2 overexpressing cerebellar Purkinje cells.
    Hayn-Leichsenring G, Liebig C, Miething A, Schulz A, Kumar S, Schwalbe M, Eiberger B, Baader SL
    Neuroscience 2011, 189, 68-78
  • Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication.
    Heidel AJ, Lawal HM, Felder M, Schilde C, Helps NR, Tunggal B, Rivero F, John U, Schleicher M, Eichinger L, Platzer M, Noegel AA, Schaap P, Glöckner G
    Genome Res 2011, 21(11), 1882-91
  • KAP1: a new link between the DNA damage response and PML nuclear bodies.
    Hemmerich P
    Cell Cycle 2011, 10(4), 576-7
  • Dynamic as well as stable protein interactions contribute to genome function and maintenance.
    Hemmerich P, Schmiedeberg L, Diekmann S
    Chromosome Res 2011, 19(1), 131-51
  • Chemical shift correlation at high MAS frequencies employing low-power symmetry-based mixing schemes.
    Herbst C, Herbst J, Leppert J, Ohlenschläger O, Görlach M, Ramachandran R
    J Biomol NMR 2011, 50(3), 277-84
  • Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors.
    Herrmann A, Haake A, Ammerpohl O, Martin-Guerrero I, Szafranski K, Stemshorn K, Nothnagel M, Kotsopoulos SK, Richter J, Warner J, Olson J, Link DR, Schreiber S, Krawczak M, Platzer M, Nürnberg P, Siebert R, Hampe J
    PLoS One 2011, 6(7), e21332
  • Hear, hear! Thyroid hormone transporters in cochlear development.
    Heuer H
    Endocrinology 2011, 152(12), 4478-80
  • Subcellular distribution of connexin45 in OFF bipolar cells of the mouse retina.
    Hilgen G, von Maltzahn J, Willecke K, Weiler R, Dedek K
    J Comp Neurol 2011, 519(3), 433-50
  • Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila.
    Hochmuth CE, Biteau B, Bohmann D, Jasper H
    Cell Stem Cell 2011, 8(2), 188-99
  • Computational analysis of high throughput sequencing data.
    Hoffmann S
    Methods Mol Biol 2011, 719, 199-217
  • Progress in the function and regulation of ADP-Ribosylation.
    Hottiger MO, Boothby* M, Koch-Nolte* F, Lüscher* B, Martin* NMB, Plummer* R, Wang* ZQ, Ziegler* M
    Sci Signal 2011, 4(174), mr5 * equal contribution
  • The ITS1-5.8S-ITS2 sequence region in the Musaceae: structure, diversity and use in molecular phylogeny.
    Hřibová E, Čížková J, Christelová P, Taudien S, de Langhe E, Doležel J
    PLoS One 2011, 6(3), e17863
  • JenAge Information Centre
    Hühne R, Thalheim T, Wagner K, Schleicher J, Sühnel J
    2011, URL
  • Creation and Comparison of Different Chip Definition Files for Affymetrix Microarrays.
    Hummert C, Mech F, Horn F, Weber M, Dryndab S, Gausmann U, Guthke R
    In: Proceedings of the International Conference on Bioinformatics and Computational Biology, BIOCOMP '11, July 12-15, 2011, Las Vegas, USA (edited by Arabnia HR, Tran QN) 2011, 1(BIC3102), 16-22, CSREA Press, Las Vegas
  • Polymorphisms in the 3'-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma.
    Jacobs G, Hellmig S, Huse K, Titz A, Franke A, Kwiatkowski R, Ott S, Kosmahl M, Fischbach W, Lucius R, Klapper W, Fölsch UR, Hampe J, Schreiber S, Rosenstiel P
    Haematologica 2011, 96(7), 987-95
  • Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange factors (GEFs) p115, PDZ-RhoGEF (PRG), and leukemia-associated RhoGEF (LARG).
    Jaiswal M, Gremer L, Dvorsky R, Haeusler LC, Cirstea IC, Uhlenbrock K, Ahmadian MR
    J Biol Chem 2011, 286(20), 18202-12
  • Metabolic homeostasis: HDACs take center stage.
    Karpac J, Jasper H
    Cell 2011, 145(4), 497-9
  • Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage.
    Karpac J, Younger A, Jasper H
    Dev Cell 2011, 20(6), 841-54
  • TNF gene cluster deletion abolishes lipopolysaccharide-mediated sensitization of the neonatal brain to hypoxic ischemic insult.
    Kendall GS, Hirstova M, Horn S, Dafou D, Acosta-Saltos A, Almolda B, Zbarsky V, Rumajogee P, Heuer H, Castellano B, Pfeffer K, Nedospasov SA, Peebles DM, Raivich G
    Lab Invest 2011, 91(3), 328-41
  • Host plant shifts affect a major defense enzyme in Chrysomela lapponica.
    Kirsch R, Vogel H, Muck A, Reichwald K, Pasteels JM, Boland W
    Proc Natl Acad Sci U S A 2011, 108(12), 4897-901
  • Protein kinase D2 is an essential regulator of murine myoblast differentiation.
    Kleger A, Loebnitz C, Pusapati GV, Armacki M, Müller M, Tümpel S, Illing A, Hartmann D, Brunner C, Liebau S, Rudolph KL, Adler G, Seufferlein T
    PLoS One 2011, 6(1), e14599
  • Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice.
    Kraft M, Cirstea IC, Voss AK, Thomas T, Goehring I, Sheikh BN, Gordon L, Scott H, Smyth GK, Ahmadian MR, Trautmann U, Zenker M, Tartaglia M, Ekici A, Reis A, Dörr HG, Rauch A, Thiel CT
    J Clin Invest 2011, 121(9), 3479-91
  • Determination of hemin-binding characteristics of proteins by a combinatorial peptide library approach.
    Kühl T, Sahoo N, Nikolajski M, Schlott B, Heinemann SH, Imhof D
    Chembiochem 2011, 12(18), 2846-55
  • Artificial linear episome-based protein expression system for protozoon Leishmania tarentolae.
    Kushnir S, Cirstea IC, Basiliya L, Lupilova N, Breitling R, Alexandrov K
    Mol Biochem Parasitol 2011, 176(2), 69-79
  • A microRNA contribution to aberrant Ras activation in gastric cancer.
    Lam EK, Wang X, Shin VY, Zhang S, Morrison H, Sun J, Ng EK, Yu J, Jin H
    Am J Transl Res 2011, 3(2), 209-18
  • Serine 312 phosphorylation is dispensable for wild-type p53 functions in vivo.
    Lee MK, Tong WM, Wang ZQ, Sabapathy K
    Cell Death Differ 2011, 18(2), 214-21
  • Point mutation at the Nbs1 Threonine 278 site does not affect mouse development, but compromises the Chk2 and Smc1 phosphorylation after DNA damage.
    Li T, Wang ZQ
    Mech Ageing Dev 2011, 132(8-9), 382-8
  • Highly parallel gene-to-BAC addressing using microarrays.
    Liu H, McNicol J, Bayer M, Morris JA, Cardle L, Marshall DF, Schulte D, Stein N, Shi BJ, Taudien S, Waugh R, Hedley PE
    Biotechniques 2011, 50(3), 165-74
  • Cancer, senescence, and aging: translation from basic research to clinics.
    Lleonart ME, Carnero A, Paciucci R, Wang ZQ, Shomron N
    J Aging Res 2011, 2011, 1-2
  • Elevated Fra-1 expression causes severe lipodystrophy.
    Luther J, Driessler F, Megges M, Hess A, Herbort B, Mandic V, Zaiss MM, Reichardt A, Zech C, Tuckermann JP, Calkhoven CF, Wagner EF, Schett G, David JP
    J Cell Sci 2011, 124(Pt 9), 1465-76
  • An investigation of the effects of MitoQ on human peripheral mononuclear cells.
    Marthandan S, Murphy MP, Billett E, Barnett Y
    Free Radic Res 2011, 45(3), 351-8
  • Inferring Boolean network structure via correlation.
    Maucher M, Kracher B, Kühl M, Kestler HA
    Bioinformatics 2011, 27(11), 1529-36
  • A radiation-induced gene expression signature as a tool to predict acute radiotherapy-induced adverse side effects.
    Mayer C, Popanda O, Greve B, Fritz E, Illig T, Eckardt-Schupp F, Gomolka M, Benner A, Schmezer P
    Cancer Lett 2011, 302(1), 20-8
  • Unlocking the barley genome by chromosomal and comparative genomics.
    Mayer KFX, Martis M, Hedley PE, Simková H, Liu H, Morris JA, Steuernagel B, Taudien S, Roessner S, Gundlach H, Kubaláková M, Suchánková P, Murat F, Felder M, Nussbaumer T, Graner A, Salse J, Endo T, Sakai H, Tanaka T, Itoh T, Sato K, Platzer M, Matsumoto T, Scholz U, Dolezel J, Waugh R, Stein N
    Plant Cell 2011, 23(4), 1249-63
  • Early relapse in ALL is identified by time to leukemia in NOD/SCID mice and is characterized by a gene signature involving survival pathways.
    Meyer LH, Eckhoff SM, Queudeville M, Kraus JM, Giordan M, Stursberg J, Zangrando A, Vendramini E, Möricke A, Zimmermann M, Schrauder A, Lahr G, Holzmann K, Schrappe M, Basso G, Stahnke K, Kestler HA, Te Kronnie G, Debatin KM
    Cancer Cell 2011, 19(2), 206-17
  • Poly(ADP-ribose) metabolism is essential for proper nucleoprotein exchange during mouse spermiogenesis.
    Meyer-Ficca ML, Ihara M, Lonchar JD, Meistrich ML, Austin CA, Min W, Wang ZQ, Meyer RG
    Biol Reprod 2011, 84(2), 218-28
  • Eukaryotic initiation factor 2{alpha} phosphorylation is required for B-cell maturation and function in mice.
    Mielke N, Schwarzer R, Calkhoven CF, Kaufman R, Dorken B, Leutz A, Jundt F
    Haematologica 2011, 96(9), 1261-8
  • Technology-specific error signatures in the 1000 Genomes Project data.
    Nothnagel M, Herrmann A, Wolf A, Schreiber S, Platzer M, Siebert R, Krawczak M, Hampe J
    Hum Genet 2011, 130(4), 505-16
  • Statistical inference of allelic imbalance from transcriptome data.
    Nothnagel M, Wolf A, Herrmann A, Szafranski K, Vater I, Brosch M, Huse K, Siebert R, Platzer M, Hampe J, Krawczak M
    Hum Mutat 2011, 32(1), 98-106
  • Endosymbiotic gene transfer and transcriptional regulation of transferred genes in Paulinella chromatophora.
    Nowack ECM, Vogel H, Groth M, Grossman AR, Melkonian** M, Glöckner** G
    Mol Biol Evol 2011, 28(1), 407-22 ** co-senior authors
  • A systems biology approach for the investigation of the heparin/heparan sulfate interactome.
    Ori A, Wilkinson MC, Fernig DG
    J Biol Chem 2011, 286(22), 19892-904
  • Fast local fragment chaining using sum-of-pair gap costs.
    Otto C, Hoffmann S, Gorodkin J, Stadler PF
    Algorithms Mol Biol 2011, 6, 4
  • A major invasion of transposable elements accounts for the large size of the Blumeria graminis f.sp. tritici genome.
    Parlange F, Oberhaensli S, Breen J, Platzer M, Taudien S, Simková H, Wicker T, Doležel J, Keller B
    Funct Integr Genomics 2011, 11(4), 671-7
  • Loss of the Protein-Tyrosine Phosphatase DEP-1/PTPRJ Drives Meningioma Cell Motility.
    Petermann A, Haase D, Wetzel A, Balavenkatraman KK, Tenev T, Gührs KH, Friedrich S, Nakamura M, Mawrin C, Böhmer FD
    Brain Pathol 2011, 21(4), 405-18
  • Der annuelle Türkise Prachtgrundkärpfling Nothobranchius furzeri als neues Modell für die Alternsforschung
    Platzer M, Reichwald K, Hartmann N, Cellerino A, Englert C
    In: Interdisziplinäre geriatrische Versorgung (edited by Heiß W), Altersmedizin aktuell 2011, Kapitel 3.1.3, ecomed Medizin, L
  • N-Benzoylated Phenoxazines and Phenothiazines: Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization.
    Prinz H, Chamasmani B, Vogel K, Bohm KJ, Aicher B, Gerlach M, Gunther EG, Amon P, Ivanov I, Muller K
    J Med Chem 2011, 54(12), 4247-63
  • Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Prinz H, Schmidt P, Böhm KJ, Baasner S, Müller K, Gerlach M, Günther EG, Unger E
    Bioorg Med Chem 2011, 19(14), 4183-91
  • Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells.
    Rauner M, Goettsch C, Stein N, Thiele S, Bornhaeuser M, De Bosscher K, Haegeman G, Tuckermann J, Hofbauer LC
    Endocrinology 2011, 152(1), 103-12
  • To be or not to be the odd one out--allele-specific transcription in pentaploid dogroses (Rosa L. sect. Caninae (DC.) Ser).
    Ritz CM, Köhnen I, Groth M, Theissen G, Wissemann V
    BMC Plant Biol 2011, 11, 37
  • Telomere shortening reduces Alzheimer's disease amyloid pathology in mice.
    Rolyan H, Scheffold A, Heinrich A, Begus-Nahrmann Y, Langkopf BH, Hölter SM, Vogt-Weisenhorn DM, Liss B, Wurst W, Lie DC, Thal DR, Biber K, Rudolph KL
    Brain 2011, 134(Pt 7), 2044-56
  • Molecular control of systemic bile Acid homeostasis by the liver glucocorticoid receptor.
    Rose AJ, Díaz MB, Reimann A, Klement J, Walcher T, Krones-Herzig A, Strobel O, Werner J, Peters A, Kleyman A, Tuckermann JP, Vegiopoulos A, Herzig S
    Cell Metab 2011, 14(1), 123-30
  • Synergistic activation by p38MAPK and glucocorticoid signaling mediates induction of M2-like tumor-associated macrophages expressing the novel CD20 homolog MS4A8A.
    Schmieder A, Schledzewski K, Michel J, Tuckermann JP, Tome L, Sticht C, Gkaniatsou C, Nicolay JP, Demory A, Faulhaber J, Kzhyshkowska J, Géraud C, Goerdt S
    Int J Cancer 2011, 129(1), 122-32
  • Liposomal Encapsulation of Glucocorticoids Alters Their Mode of Action in the Treatment of Experimental Autoimmune Encephalomyelitis.
    Schweingruber N, Haine A, Tiede K, Karabinskaya A, van den Brandt J, Wüst S, Metselaar JM, Gold R, Tuckermann JP, Reichardt HM, Lühder F
    J Immunol 2011, 187(8), 4310-8
  • Association of TLR7 variants with AIDS-like disease and AIDS vaccine efficacy in rhesus macaques.
    Siddiqui RA, Krawczak M, Platzer M, Sauermann U
    PLoS One 2011, 6(10), e25474
  • New furin inhibitors based on weakly basic amidinohydrazones.
    Sielaff F, Than ME, Bevec D, Lindberg I, Steinmetzer T
    Bioorg Med Chem Lett 2011, 21(2), 836-40
  • The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation.
    Sirma H, Kumar M, Meena JK, Witt B, Weise JM, Lechel A, Ande S, Sakk V, Guguen-Guillouzo C, Zender L, Rudolph KL, Günes C
    Gastroenterology 2011, 141(1), 326-37, 337.e1-3
  • Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction.
    Sperka T, Song Z, Morita Y, Nalapareddy K, Guachalla LM, Lechel A, Begus-Nahrmann Y, Burkhalter MD, Mach M, Schlaudraff F, Liss B, Ju Z, Speicher MR, Rudolph KL
    Nat Cell Biol 2011, 14(1), 73-9 published during change of institution
  • p38α mitogen-activated protein kinase inhibitors, a patent review (2005 – 2011)
    Stefan F, Solveigh C K, Stefan A L
    Expert Opin Ther Pat 2011, 21(12), 1843-66
  • Revealing the position of the substrate in nickel superoxide dismutase: a model study.
    Tietze D, Voigt S, Mollenhauer D, Tischler M, Imhof D, Gutmann T, González L, Ohlenschläger O, Breitzke H, Görlach M, Buntkowsky G
    Angew Chem Int Ed Engl 2011, 50(13), 2946-50
  • Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled alpha-subunits.
    Valkova* C, Albrizio* M, Röder IV, Schwake M, Betto R, Rudolf** R, Kaether** C
    Proc Natl Acad Sci U S A 2011, 108(2), 621-5 * equal contribution, ** co-corresponding authors
  • Tumor necrosis factor inhibits glucocorticoid receptor function in mice: a strong signal toward lethal shock.
    Van Bogaert T, Vandevyver S, Dejager L, Van Hauwermeiren F, Pinheiro I, Petta I, Engblom D, Kleyman A, Schütz G, Tuckermann J, Libert C
    J Biol Chem 2011, 286(30), 26555-67
  • In vitro gap-directed translesion DNA synthesis of an abasic site involving human DNA polymerases epsilon, lambda, and beta.
    Villani G, Hubscher U, Gironis N, Parkkinen S, Pospiech H, Shevelev I, di Cicco G, Markkanen E, Syväoja JE, Tanguy Le Gac N
    J Biol Chem 2011, 286(37), 32094-104
  • Addicted to Myc--but why?
    von Eyss B, Eilers M
    Genes Dev 2011, 25(9), 895-7
  • Regeneration of the exocrine pancreas is delayed in telomere-dysfunctional mice.
    von Figura G, Wagner M, Nalapareddy K, Hartmann D, Kleger A, Guachalla LM, Rolyan H, Adler G, Rudolph KL
    PLoS One 2011, 6(2), e17122
  • Connexin39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle.
    von Maltzahn J, Wulf V, Matern G, Willecke K
    Exp Cell Res 2011, 317(8), 1169-78
  • Immunoaging induced by hematopoietic stem cell aging.
    Wang J, Geiger H, Rudolph KL
    Curr Opin Immunol 2011, 23(4), 532-6
  • Telomere shortening impairs regeneration of the olfactory epithelium in response to injury but not under homeostatic conditions.
    Watabe-Rudolph M, Begus-Nahrmann Y, Lechel A, Rolyan H, Scheithauer MO, Rettinger G, Thal DR, Rudolph KL
    PLoS One 2011, 6(11), e27801
  • FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.
    Welz PS, Wullaert A, Vlantis K, Kondylis V, Fernández-Majada V, Ermolaeva M, Kirsch P, Sterner-Kock A, van Loo G, Pasparakis M
    Nature 2011, 477(7364), 330-4
  • Frequent gene movement and pseudogene evolution is common to the large and complex genomes of wheat, barley, and their relatives.
    Wicker T, Mayer KF, Gundlach H, Martis M, Steuernagel B, Scholz U, Simková H, Kubaláková M, Choulet F, Taudien S, Platzer M, Feuillet C, Fahima T, Budak H, Dolezel J, Keller B, Stein N
    Plant Cell 2011, 23(5), 1706-18
  • Origin of land plants: do conjugating green algae hold the key?
    Wodniok S, Brinkmann H, Glöckner G, Heidel AJ, Philippe H, Melkonian M, Becker B
    BMC Evol Biol 2011, 11, 104
  • Segrosome assembly at the pliable parH centromere.
    Wu M, Zampini M, Bussiek M, Hoischen C, Diekmann S, Hayes F
    Nucleic Acids Res 2011, 39(12), 5082-97
  • Telomere dysfunction-related serological markers are associated with type 2 diabetes.
    Xiao F, Zheng X, Cui M, Shi G, Chen X, Li R, Song Z, Rudolph KL, Chen B, Ju Z
    Diabetes Care 2011, 34(10), 2273-8
  • The first Sino-German Symposium on DNA Repair and Human Diseases.
    Xu* X, Eilers* M, Xiao* W, Du* LL, Bürkle* A, Wiesmüller* L, Wang* ZQ
    DNA Repair 2011, 10(3), 349-54 * equal contribution
  • RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice.
    Yu C, Li Y, Holmes A, Szafranski K, Faulkes CG, Coen CW, Buffenstein R, Platzer M, de Magalhães JP, Church GM
    PLoS One 2011, 6(11), e26729

Publications 2010:

  • The small RNA expression profile of the developing murine urinary and reproductive systems.
    Aguilar ALG, Piskol R, Beitzinger M, Zhu JY, Kruspe D, Aszodi A, Moser M, Englert C, Meister G
    FEBS Lett 2010, 584(21), 4426-34
  • Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans.
    Ashworth S, Teng B, Kaufeld J, Miller E, Tossidou I, Englert C, Bollig F, Staggs L, Roberts ISD, Park JK, Haller H, Schiffer M
    PLoS One 2010, 5(9), e12626
  • Rigid assembly and Monte Carlo models of stable and unstable chromatin structures: the effect of nucleosomal spacing.
    Aumann* F, Sühnel* J, Langowski J, Diekmann S
    Theor Chem Acc 2010, 125, 217-31 * equal contribution
  • Transcriptomic changes arising during light-induced sporulation in Physarum polycephalum.
    Barrantes I, Glockner G, Meyer S, Marwan W
    BMC Genomics 2010, 11, 115
  • Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics.
    Becker GL, Sielaff F, Than ME, Lindberg I, Routhier S, Day R, Lu Y, Garten W, Steinmetzer T
    J Med Chem 2010, 53(3), 1067-75
  • Extrinsic regulation of satellite cell specification.
    Bentzinger CF, von Maltzahn J, Rudnicki MA
    Stem Cell Res Ther 2010, 1(3), 27
  • Bioelectromagnetic field effects on cancer cells and mice tumors.
    Berg H, Günther B, Hilger I, Radeva M, Traitcheva N, Wollweber L
    Electromagn Biol Med 2010, 29(4), 132-43
  • Posttranslational modification of human glyoxalase 1 indicates redox-dependent regulation.
    Birkenmeier G, Stegemann C, Hoffmann R, Günther R, Huse K, Birkemeyer C
    PLoS One 2010, 5(4), e10399
  • Lifespan extension by preserving proliferative homeostasis in Drosophila.
    Biteau B, Karpac J, Supoyo S, Degennaro M, Lehmann R, Jasper H
    PLoS Genet 2010, 6(10), e1001159
  • Impact papers on aging in 2009.
    Blagosklonny MV, Campisi J, Sinclair DA, Bartke A, Blasco MA, Bonner WM, Bohr VA, Brosh RM, Brunet A, Depinho RA, Donehower LA, Finch CE, Finkel T, Gorospe M, Gudkov AV, Hall MN, Hekimi S, Helfand SL, Karlseder J, Kenyon C, Kroemer G, Longo V, Nussenzweig A, Osiewacz HD, Peeper DS, Rando TA, Rudolph KL, Sassone-Corsi P, Serrano M, Sharpless NE, Skulachev VP, Tilly JL, Tower J, Verdin E, Vijg J
    Aging (Albany NY) 2010, 2(3), 111-21
  • Radiation Induced Cytoplasmic Signaling
    Böhmer FD, Weiss C, Herrlich P
    In: Handbook of Cell Signaling (edited by Ralph A. Bradshaw and Edward A. Dennis) 2010, Volume 3(Chapter 267), 2225-30, Elsevier Inc. Academic
  • Assembly dynamics of PML nuclear bodies in living cells.
    Brand P, Lenser T, Hemmerich P
    PMC Biophys 2010, 3(1), 3
  • 1H, 13C and 15N resonance assignment of a zinc-binding methionine sulfoxide reductase type-B from the thermophilic archeabacterium Methanothermobacter thermoautotrophicus.
    Carella M, Ohlenschläger O, Ramachandran R, Görlach M
    Biomol NMR Assign 2010, 4(1), 93-5
  • Thymus-derived glucocorticoids mediate androgen effects on thymocyte homeostasis.
    Chen Y, Qiao S, Tuckermann J, Okret S, Jondal M
    FASEB J 2010, 24(12), 5043-51
  • Containment of extended length polymorphisms in silk proteins.
    Chinali A, Vater W, Rudakoff B, Sponner A, Unger E, Grosse F, Guehrs KH, Weisshart K
    J Mol Evol 2010, 70(4), 325-38
  • A restricted spectrum of NRAS mutations causes Noonan syndrome.
    Cirstea IC, Kutsche K, Dvorsky R, Gremer L, Carta C, Horn D, Roberts AE, Lepri F, Merbitz-Zahradnik T, König R, Kratz CP, Pantaleoni F, Dentici ML, Joshi VA, Kucherlapati RS, Mazzanti L, Mundlos S, Patton MA, Silengo MC, Rossi C, Zampino G, Digilio C, Stuppia L, Seemanova E, Pennacchio LA, Gelb BD, Dallapiccola B, Wittinghofer A, Ahmadian MR, Tartaglia M, Zenker M
    Nat Genet 2010, 42(1), 27-9
  • Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis.
    Dalloul RA, Long JA, Zimin AV, Aslam L, Beal K, Blomberg LA, Bouffard P, Burt DW, Crasta O, Crooijmans RPMA, Cooper K, Coulombe RA, De S, Delany ME, Dodgson JB, Dong JJ, Evans C, Frederickson KM, Flicek P, Florea L, Folkerts O, Groenen MAM, Harkins TT, Herrero J, Hoffmann S, Megens HJ, Jiang A, de Jong P, Kaiser P, Kim H, Kim KW, Kim S, Langenberger D, Lee MK, Lee T, Mane S, Marcais G, Marz M, McElroy AP, Modise T, Nefedov M, Notredame C, Paton IR, Payne WS, Pertea G, Prickett D, Puiu D, Qioa D, Raineri E, Ruffier M, Salzberg SL, Schatz MC, Scheuring C, Schmidt CJ, Schroeder S, Searle SMJ, Smith EJ, Smith J, Sonstegard TS, Stadler PF, Tafer H, Tu ZJ, Van Tassell CP, Vilella AJ, Williams KP, Yorke JA, Zhang L, Zhang HB, Zhang X, Zhang Y, Reed KM
    PLoS Biol 2010, 8(9)
  • The nuclear isoform of the LIM domain protein Trip6 integrates activating and repressing signals at the promoter-bound glucocorticoid receptor.
    Diefenbacher ME, Litfin M, Herrlich P, Kassel O
    Mol Cell Endocrinol 2010, 320(1-2), 58-66
  • Systems biology to battle vascular disease.
    Dominiczak AF, Herget-Rosenthal S, Delles C, Fliser D, Fournier I, Graber A, Girolami M, Holmes E, Lang F, Molina F, Nicholson J, Remuzzi G, Rossing P, Rudolph KL, Wolkenhauer O, Xenarios I, Zubarev R, Zubov D, Vlahou A, Schanstra JP
    Nephrol Dial Transplant 2010, 25(4), 1019-22
  • ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.
    Dormann D, Rodde R, Edbauer D, Bentmann E, Fischer I, Hruscha A, Than ME, Mackenzie IRA, Capell A, Schmid B, Neumann M, Haass C
    EMBO J 2010, 29(16), 2841-57
  • Recovery of tubulin functions after freeze-drying in the presence of trehalose.
    Dráberová E, Sulimenko V, Sulimenko T, Böhm KJ, Dráber P
    Anal Biochem 2010, 397(1), 67-72
  • Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch.
    Duchardt-Ferner E, Weigand JE, Ohlenschläger O, Schmidtke SR, Suess B, Wöhnert J
    Angew Chem Int Ed Engl 2010, 49(35), 6216-9
  • Brain ischemic preconditioning does not require PARP-1.
    Faraco G, Blasi F, Min W, Wang ZQ, Moroni F, Chiarugi A
    Stroke 2010, 41(1), 181-3
  • Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.
    Frijters R, Fleuren W, Toonen EJM, Tuckermann JP, Reichardt HM, van der Maaden H, van Elsas A, van Lierop MJ, Dokter W, de Vlieg J, Alkema W
    BMC Genomics 2010, 11, 359
  • Endothelial cell adhesion to the extracellular matrix induces c-Src-dependent VEGFR-3 phosphorylation without the activation of the receptor intrinsic kinase activity.
    Galvagni F, Pennacchini S, Salameh A, Rocchigiani M, Neri F, Orlandini M, Petraglia F, Gotta S, Sardone GL, Matteucci G, Terstappen GC, Oliviero S
    Circ Res 2010, 106(12), 1839-48
  • Purification and crystallization of human Cu/Zn superoxide dismutase recombinantly produced in the protozoan Leishmania tarentolae.
    Gazdag EM, Cirstea IC, Breitling R, Lukes J, Blankenfeldt W, Alexandrov K
    Acta Crystallogr Sect F Struct Biol Cryst Commun 2010, 66(Pt 8), 871-7
  • Impaired endothelial repair capacity of early endothelial progenitor cells in prehypertension: relation to endothelial dysfunction.
    Giannotti G, Doerries C, Mocharla PS, Mueller MF, Bahlmann FH, Horvàth T, Jiang H, Sorrentino SA, Steenken N, Manes C, Marzilli M, Rudolph KL, Lüscher TF, Drexler H, Landmesser U
    Hypertension 2010, 55(6), 1389-97
  • Autophagy and apoptosis in planarians.
    González-Estévez C, Saló E
    Apoptosis 2010, 15(3), 279-92
  • Calculation of the Masses of All Fundamental Elementary Particles with an Accuracy of Approx. 1%.
    Greulich KO
    J Mod Phys 2010, 1(5), 300-2
  • Single molecule experiments challenge the strict wave-particle dualism of light.
    Greulich KO
    Int J Mol Sci 2010, 11(1), 304-11
  • Optical Tweezers.
    Greulich KO
    In: eLS 2010, published online, John Wiley and
  • Single-Molecule Light Microscopy.
    Greulich KO, Uhl V
    In: eLS 2010, published online, John Wiley and
  • A dexter exo within p53.
    Grosse F
    Cell Cycle 2010, 9(6), 1025-30
  • ROS induced DNA damage and checkpoint responses: influences on aging?
    Guachalla LM, Rudolph KL
    Cell Cycle 2010, 9(20), 4058-60
  • Telomere length of patients with major depression is shortened but independent from therapy and severity of the disease.
    Hartmann N, Boehner M, Groenen F, Kalb R
    Depress Anxiety 2010, 27(12), 1111-6
  • Linking chemical and microbial diversity in marine sponges: possible role for poribacteria as producers of methyl-branched fatty acids.
    Hochmuth T, Niederkrüger H, Gernert C, Siegl A, Taudien S, Platzer M, Crews P, Hentschel U, Piel J
    Chembiochem 2010, 11(18), 2572-8
  • Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development.
    Hristova M, Cuthill D, Zbarsky V, Acosta-Saltos A, Wallace A, Blight K, Buckley SMK, Peebles D, Heuer H, Waddington SN, Raivich G
    Glia 2010, 58(1), 11-28
  • The JenAge Information Centre, an information hub for ageing research and systems biology
    Hühne R, Thalheim T, Schleicher J, Wagner K, Sühnel J
    2010, URL
  • Metabolic regulation of stem cell behavior and implications for aging.
    Jasper H, Jones DL
    Cell Metab 2010, 12(6), 561-5
  • Genomic characterisation of the ichthyotoxic prymnesiophyte Chrysochromulina polylepis, and the expression of polyketide synthase genes in synchronized cultures.
    John U, Beszteri S, Glöckner G, Singh R, Medlin L, Cembella AD
    Eur J Phycol 2010, 45(3), 215-29 published during change of institution
  • A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway.
    Kim MS, Yoon SK, Bollig F, Kitagaki J, Hur W, Whye NJ, Wu YP, Rivera MN, Park JY, Kim HS, Malik K, Bell DW, Englert C, Perantoni AO, Lee SB
    J Biol Chem 2010, 285(19), 14585-93
  • What's new in neurofibromatosis? Proceedings from the 2009 NF Conference: new frontiers.
    Kissil JL, Blakeley JO, Ferner RE, Huson SM, Kalamarides M, Mautner VF, McCormick F, Morrison H, Packer R, Ramesh V, Ratner N, Rauen KA, Stevenson DA, Hunter-Schaedle K, North K
    Am J Med Genet A 2010, 152A(2), 269-83
  • A highly efficient multi-core algorithm for clustering extremely large datasets.
    Kraus JM, Kestler HA
    BMC Bioinformatics 2010, 11, 169
  • Telomerase deficiency impairs glucose metabolism and insulin secretion.
    Kuhlow D, Florian S, von Figura G, Weimer S, Schulz N, Petzke KJ, Zarse K, Pfeiffer AFH, Rudolph KL, Ristow M
    Aging (Albany NY) 2010, 2(10), 650-8
  • Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development.
    Landgraf K, Bollig F, Trowe MO, Besenbeck B, Ebert C, Kruspe D, Kispert A, Hänel F, Englert C
    Mol Cell Biol 2010, 30(24), 5764-75
  • Identification and classification of small RNAs in transcriptome sequence data.
    Langenberger D, Bermudez-Santana CI, Stadler PF, Hoffmann S
    Pac Symp Biocomput 2010, 80-7
  • Alpha2-macroglobulin inhibits the malignant properties of astrocytoma cells by impeding beta-catenin signaling.
    Lindner I, Hemdan NYA, Buchold M, Huse K, Bigl M, Oerlecke I, Ricken A, Gaunitz F, Sack U, Naumann A, Hollborn M, Thal D, Gebhardt R, Birkenmeier G
    Cancer Res 2010, 70(1), 277-87
  • Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase in the presence of replication protein A and proliferating-cell nuclear antigen.
    Locatelli GA, Pospiech H, Tanguy Le Gac N, van Loon B, Hubscher U, Parkkinen S, Syväoja JE, Villani G
    Biochem J 2010, 429(3), 573-82
  • Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells on combined tumor necrosis factor receptor-1/lymphotoxin beta-receptor NF-kappaB signaling.
    Lötzer* K, Döpping* S, Connert* S, Gräbner R, Spanbroek R, Lemser B, Beer M, Hildner M, Hehlgans T, van der Wall M, Mebius RE, Lovas A, Randolph GJ, Weih* F, Habenicht* AJR
    Arterioscler Thromb Vasc Biol 2010, 30(3), 395-402 * equal contribution
  • The origins of eukaryotic-like proteins in Legionella pneumophila.
    Lurie-Weinberger MN, Gomez-Valero L, Merault N, Glöckner G, Buchrieser C, Gophna U
    Int J Med Microbiol 2010, 300(7), 470-81
  • Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones.
    Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K, Nyabi O, Haigh K, Naessens M, Haenebalcke L, Tuckermann JP, Tjwa M, Carmeliet P, Mandic V, David JP, Behrens A, Nagy A, Carmeliet G, Haigh JJ
    EMBO J 2010, 29(2), 424-41
  • Processing of the NF-kappa B2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation.
    Maruyama T, Fukushima H, Nakao K, Shin M, Yasuda H, Weih F, Doi T, Aoki K, Alles N, Ohya K, Hosokawa R, Jimi E
    J Bone Miner Res 2010, 25(5), 1058-67
  • An unusual peptide from Conus villepinii: synthesis, solution structure, and cardioactivity.
    Miloslavina A, Ebert C, Tietze D, Ohlenschläger O, Englert C, Görlach M, Imhof D
    Peptides 2010, 31(7), 1292-300
  • Deletion of the nuclear isoform of poly(ADP-ribose) glycohydrolase (PARG) reveals its function in DNA repair, genomic stability and tumorigenesis.
    Min W, Cortes U, Herceg Z, Tong WM, Wang ZQ
    Carcinogenesis 2010, 31(12), 2058-65
  • C/EBPalpha enters the nucleolus.
    Müller C, Calkhoven CF
    Cell Cycle 2010, 9(7), 1229-30
  • CHK2-independent induction of telomere dysfunction checkpoints in stem and progenitor cells.
    Nalapareddy K, Choudhury AR, Gompf A, Ju Z, Ravipati S, Leucht T, Lechel A, Rudolph KL
    EMBO Rep 2010, 11(8), 619-25
  • Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety.
    Nickel HC, Schmidt P, Böhm KJ, Baasner S, Müller K, Gerlach M, Unger E, Günther EG, Prinz H
    Eur J Med Chem 2010, 45(8), 3420-38
  • Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns.
    Norden J, Grieskamp T, Lausch E, van Wijk B, van den Hoff MJB, Englert C, Petry M, Mommersteeg MTM, Christoffels VM, Niederreither K, Kispert A
    Circ Res 2010, 106(7), 1212-20
  • Feedback between p21 and reactive oxygen production is necessary for cell senescence.
    Passos JF, Nelson G, Wang C, Richter T, Simillion C, Proctor CJ, Miwa S, Olijslagers S, Hallinan J, Wipat A, Saretzki G, Rudolph KL, Kirkwood TBL, von Zglinicki T
    Mol Syst Biol 2010, 6, 347
  • The Initiation Step of Eukaryotic DNA Replication.
    Pospiech H, Grosse F, Pisani FM
    In: Genome Stability and Human Diseases, Subcellular Biochemistry 2010, 50, 79-104, Springer Netherlands, Do
  • Synthesis of 2,6-aceanthrylenedione, a cyclic vinylog of anthraquinone.
    Prinz H, Böhm KJ, Müller K
    J Org Chem 2010, 75(11), 3867-70
  • The unique complexity of the CYP3A4 upstream region suggests a nongenetic explanation of its expression variability.
    Qiu H, Mathäs M, Nestler S, Bengel C, Nem D, Gödtel-Armbrust U, Lang T, Taudien S, Burk O, Wojnowski L
    Pharmacogenet Genomics 2010, 20(3), 167-78
  • Potential negative impacts and low effectiveness in the use of African annual killifish in the biocontrol of aquatic mosquito larvae in temporary water bodies.
    Reichard M, Watters BR, Wildekamp RH, Sonnenberg R, Nagy B, Polacik M, Valdesalici S, Cellerino A, Cooper BJ, Hengstler H, Rosenstock J, Sainthouse I
    Parasit Vectors 2010, 3, 89
  • Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
    Rudd TR, Uniewicz KA, Ori A, Guimond SE, Skidmore MA, Gaudesi D, Xu R, Turnbull JE, Guerrini M, Torri G, Siligardi G, Wilkinson MC, Fernig DG, Yates EA
    Org Biomol Chem 2010, 8(23), 5390-7
  • Molecular Mechanisms of Adult Stem Cell Aging
    Rudolph KL (ed)
    Book series: Else Kröner-Fresenius-Symposia 2010, 1, Karger Verlag, Basel, Switzerlan
  • Molecular analysis of cataract families in India: new mutations in the CRYBB2 and GJA3 genes and rare polymorphisms.
    Santhiya ST, Kumar GS, Sudhakar P, Gupta N, Klopp N, Illig T, Söker T, Groth M, Platzer M, Gopinath PM, Graw J
    Mol Vis 2010, 16, 1837-47
  • A subtle alternative splicing event of the Na(V)1.8 voltage-gated sodium channel is conserved in human, rat, and mouse.
    Schirmeyer J, Szafranski K, Leipold E, Mawrin C, Platzer M, Heinemann SH
    J Mol Neurosci 2010, 41(2), 310-4
  • The centrosome and mitotic spindle apparatus in cancer and senescence.
    Schmidt S, Essmann F, Cirstea IC, Kuck F, Thakur HC, Singh M, Kletke A, Jänicke RU, Wiek C, Hanenberg H, Ahmadian MR, Schulze-Osthoff K, Nürnberg B, Piekorz RP
    Cell Cycle 2010, 9(22), 4469-73
  • The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program.
    Schmidt S, Schneider L, Essmann F, Cirstea IC, Kuck F, Kletke A, Jänicke RU, Wiek C, Hanenberg H, Ahmadian MR, Schulze-Osthoff K, Nürnberg B, Piekorz RP
    Oncogene 2010, 29(46), 6184-92
  • Characterisation of prostate cancer lesions in heterozygous Men1 mutant mice.
    Seigne C, Fontanière S, Carreira C, Lu J, Tong WM, Fontanière B, Wang ZQ, Zhang CX, Frappart L
    BMC Cancer 2010, 10, 395
  • Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo.
    Shalapour S, Deiser K, Sercan O, Tuckermann J, Minnich K, Willimsky G, Blankenstein T, Hämmerling GJ, Arnold B, Schüler T
    Eur J Immunol 2010, 40(9), 2391-400
  • The primary transcriptome of the major human pathogen Helicobacter pylori.
    Sharma CM, Hoffmann S, Darfeuille F, Reignier J, Findeiss S, Sittka A, Chabas S, Reiche K, Hackermüller J, Reinhardt R, Stadler PF, Vogel J
    Nature 2010, 464(7286), 250-5
  • A cytohesin homolog in Dictyostelium amoebae.
    Shina MC, Müller R, Blau-Wasser R, Glöckner G, Schleicher M, Eichinger L, Noegel AA, Kolanus W
    PLoS One 2010, 5(2), e9378
  • Identification and characterization of NAGNAG alternative splicing in the moss Physcomitrella patens.
    Sinha R, Zimmer AD, Bolte K, Lang D, Reski R, Platzer M, Rensing SA, Backofen R
    BMC Plant Biol 2010, 10, 76
  • Function of TopBP1 in genome stability.
    Sokka M, Parkkinen S, Pospiech H, Syväoja JE
    In: Genome Stability and Human Diseases, Subcellular Biochemistry 2010, 50, 119-141, Springer Netherlands, D
  • Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood.
    Song Z, von Figura G, Liu Y, Kraus JM, Torrice C, Dillon P, Rudolph-Watabe M, Ju Z, Kestler HA, Sanoff H, Lenhard Rudolph K
    Aging Cell 2010, 9(4), 607-15
  • Alterations of the systemic environment are the primary cause of impaired B and T lymphopoiesis in telomere-dysfunctional mice.
    Song Z, Wang J, Guachalla LM, Terszowski G, Rodewald HR, Ju Z, Rudolph KL
    Blood 2010, 115(8), 1481-9
  • The pivotal role of the alternative NF-kappaB pathway in maintenance of basal bone homeostasis and osteoclastogenesis.
    Soysa NS, Alles N, Weih D, Lovas A, Mian AH, Shimokawa H, Yasuda H, Weih F, Jimi E, Ohya K, Aoki K
    J Bone Miner Res 2010, 25(4), 809-18 excellent by "Faculty of 1000"
  • Synthesis, antiproliferative activity and inhibition of tubulin polymerization by anthracenone-based oxime derivatives.
    Surkau G, Böhm KJ, Müller K, Prinz H
    Eur J Med Chem 2010, 45(8), 3354-64
  • Assisted reproductive technologies do not enhance the variability of DNA methylation imprints in human.
    Tierling S, Souren NY, Gries J, Loporto C, Groth M, Lutsik P, Neitzel H, Utz-Billing I, Gillessen-Kaesbach G, Kentenich H, Griesinger G, Sperling K, Schwinger E, Walter J
    J Med Genet 2010, 47(6), 371-6
  • Development of a functional cis-prolyl bond biomimetic and mechanistic implications for nickel superoxide dismutase.
    Tietze D, Tischler M, Voigt S, Imhof D, Ohlenschläger O, Görlach M, Buntkowsky G
    Chemistry 2010, 16(25), 7572-8
  • Meeting report: nuclear receptors: transcription factors and drug targets connecting basic research with translational medicine.
    Tuckermann J, Bourguet W, Mandrup S
    Mol Endocrinol 2010, 24(7), 1311-21
  • Differential scanning fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a screening test for binding specificity.
    Uniewicz KA, Ori A, Xu R, Ahmed Y, Wilkinson MC, Fernig DG, Yates EA
    Anal Chem 2010, 82(9), 3796-802
  • Transcriptome analysis of the sex pheromone gland of the noctuid moth Heliothis virescens.
    Vogel H, Heidel AJ, Heckel DG, Groot AT
    BMC Genomics 2010, 11, 29
  • C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals.
    Wethmar K, Bégay V, Smink JJ, Zaragoza K, Wiesenthal V, Dörken B, Calkhoven CF, Leutz A
    Genes Dev 2010, 24(1), 15-20
  • A poke into the diversity and associations within human anterior nare microbial communities.
    Wos-Oxley ML, Plumeier I, von Eiff C, Taudien S, Platzer M, Vilchez-Vargas R, Becker K, Pieper DH
    ISME J 2010, 4(7), 839-51
  • Comparative gene expression in toxic versus non-toxic strains of the marine dinoflagellate Alexandrium minutum.
    Yang I, John U, Beszteri S, Glöckner G, Krock B, Goesmann A, Cembella AD
    BMC Genomics 2010, 11, 248
  • Molecular characterization of nuclear DNA helicase II (RNA helicase A).
    Zhang S, Grosse F
    Methods Mol Biol 2010, 587, 291-302
  • Genomic analysis of the 55 kDa subunit of DNA polymerase epsilon in human intracranial neoplasms.
    Zhou Q, Lehtonen T, Lehtonen J, Laakso S, Szymas J, Pospiech H, Huoponen K, Syväoja J, Collan Y
    Cancer Genomics Proteomics 2010, 7(3), 143-6
  • Characterization of mesonephric development and regeneration using transgenic zebrafish.
    Zhou W, Boucher RC, Bollig F, Englert C, Hildebrandt F
    AM J PHYSIOL-RENAL 2010, 299(5), F1040-7

Publications 2009:

  • Bacterial L-forms.
    Allan EJ, Hoischen C, Gumpert J
    In: Advances in Applied Microbiology 2009, 68, 1-39, Elsevier Inc., New York, N
  • Exogenous brain-derived neurotrophic factor (BDNF) reverts phenotypic changes in the retinas of transgenic mice lacking the BDNF gene.
    Arango-González* B, Cellerino* A, Kohler K
    Invest Ophthalmol Vis Sci 2009, 50(3), 1416-22 * equal contribution, published during change of institution
  • Conditional inactivation of the NBS1 gene in the mouse central nervous system leads to neurodegeneration and disorganization of the visual system.
    Baranes K, Raz-Prag D, Nitzan A, Galron R, Ashery-Padan R, Rotenstreich Y, Assaf Y, Shiloh Y, Wang ZQ, Barzilai A, Solomon AS
    Exp Neurol 2009, 218(1), 24-32
  • p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice.
    Begus-Nahrmann Y, Lechel A, Obenauf AC, Nalapareddy K, Peit E, Hoffmann E, Schlaudraff F, Liss B, Schirmacher P, Kestler H, Danenberg E, Barker N, Clevers H, Speicher MR, Rudolph KL
    Nat Genet 2009, 41(10), 1138-43
  • Deposition of palladium nanoparticles on self-assembled, zinc-induced tubulin macrotubes and sheets.
    Behrens S, Habicht W, Wenzel W, Böhm KJ
    J Nanosci Nanotechnol 2009, 9(12), 6858-65
  • It's all about balance: p53 and aging.
    Biteau B, Jasper H
    Aging (Albany NY) 2009, 1(11), 884-6
  • A lytic enzyme cocktail from Streptomyces sp. B578 for the control of lactic and acetic acid bacteria in wine.
    Blättel V, Wirth K, Claus H, Schlott B, Pfeiffer P, König H
    Appl Microbiol Biotechnol 2009, 83(5), 839-48
  • Klotho is a substrate for alpha-, beta- and gamma-secretase.
    Bloch* L, Sineshchekova O, Reichenbach D, Reiss K, Saftig P, Kuro-o M, Kaether C
    FEBS Lett 2009, 583(19), 3221-4 * equal contribution
  • Steady state microtubules and GTP hydrolysis.
    Böhm KJ
    Eur J Cell Biol Suppl 2009, 88(Suppl 1), SE2-24
  • A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros.
    Bollig F, Perner B, Besenbeck B, Köthe S, Ebert C, Taudien S, Englert C
    Development 2009, 136(17), 2883-92
  • Sequence-specific physical properties of African green monkey alpha-satellite DNA contribute to centromeric heterochromatin formation.
    Bussiek M, Hoischen C, Diekmann S, Bennink ML
    J Struct Biol 2009, 167(1), 36-46
  • Life Extension in the Short-Lived Fish Nothobranchius furzeri
    Cellerino A
    In: Aging Medicine (edited by Sell C, Lorenzini A, BrownBorg HM), Life-Span Extension: Single-Cell Organisms to Man 2009, 157-71, Humana Press Inc., Totow
  • Enhancement of chemokine expression by interferon beta therapy in patients with multiple sclerosis.
    Cepok S, Schreiber H, Hoffmann S, Zhou D, Neuhaus O, von Geldern G, Hochgesand S, Nessler S, Rothhammer V, Lang M, Hartung HP, Hemmer B
    Arch Neurol 2009, 66(10), 1216-23
  • Systematic evaluation of the effect of common SNPs on pre-mRNA splicing.
    ElSharawy A, Hundrieser B, Brosch M, Wittig M, Huse K, Platzer M, Becker A, Simon M, Rosenstiel P, Schreiber S, Krawczak M, Hampe J
    Hum Mutat 2009, 30(4), 625-32
  • Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting.
    Fisch KM, Gurgui C, Heycke N, van der Sar SA, Anderson SA, Webb VL, Taudien S, Platzer M, Rubio BK, Robinson SJ, Crews P, Piel J
    Nat Chem Biol 2009, 5(7), 494-501
  • A cost-effective amino-acid-type selective isotope labeling of proteins expressed in Leishmania tarentolae.
    Foldynová-Trantirková S, Matulová J, Dötsch V, Löhr F, Cirstea I, Alexandov K, Breitling R, Lukes J, Trantírek L
    J Biomol Struct Dyn 2009, 26(6), 755-61
  • An intronic single base exchange leads to a brown adipose tissue-specific loss of Ucp3 expression and an altered body mass trajectory.
    Fromme T, Hoffmann C, Nau K, Rozman J, Reichwald K, Utting M, Platzer M, Klingenspor M
    Physiol Genomics 2009, 38(1), 54-62
  • Aging in the lympho-hematopoietic stem cell compartment.
    Geiger H, Rudolph KL
    Trends Immunol 2009, 30(7), 360-5
  • p38-{gamma}-dependent gene silencing restricts entry into the myogenic differentiation program.
    Gillespie MA, Le Grand F, Scimè A, Kuang S, von Maltzahn J, Seale V, Cuenda A, Ranish JA, Rudnicki MA
    J Cell Biol 2009, 187(7), 991-1005
  • Centromere sequence and dynamics in Dictyostelium discoideum.
    Glöckner G, Heidel AJ
    Nucleic Acids Res 2009, 37(6), 1809-16
  • Autophagy meets planarians.
    González-Estévez C
    Autophagy 2009, 5(3), 290-7
  • Diverse miRNA spatial expression patterns suggest important roles in homeostasis and regeneration in planarians.
    González-Estévez C, Arseni V, Thambyrajah RS, Felix DA, Aboobaker AA
    Int J Dev Biol 2009, 53(4), 493-505
  • A non-quantum mechanical explanation of the single photon double slit experiment.
    Greulich KO
    In: The Nature of Light: What are Photons?, Superposition and Divisibility of Photons I (edited by Roychoudhuri C, Kracklauer AF, Khrennikov Andrei Yu), Proceedings of SPIE 2009, 7421, 742104, SPIE Press, Bellingham,
  • Another loophole for the Bell inequalities.
    Greulich KO
    In: The Nature of Light: What are Photons?, Critical Concepts and Interpretations (edited by Roychoudhuri C, Kracklauer AF, Khrennikov Andrei Yu), Proceedings of SPIE 2009, 7421, 74210S, SPIE Press, Bellingham,
  • Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice.
    Guachalla LM, Ju Z, Koziel R, von Figura G, Song Z, Fusser M, Epe B, Jansen-Durr P, Rudolph KL
    Aging (Albany NY) 2009, 1(3), 303-15
  • Improve organ health by chewing up old proteins?
    Guachalla LM, Rudolph KL
    Hepatology 2009, 49(1), 330-2
  • Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution.
    Guimond SE, Rudd TR, Skidmore MA, Ori A, Gaudesi D, Cosentino C, Guerrini M, Edge R, Collison D, McInnes E, Torri G, Turnbull JE, Fernig DG, Yates EA
    Biochemistry 2009, 48(22), 4772-9
  • Minireview: Pathophysiological importance of thyroid hormone transporters.
    Heuer H, Visser TJ
    Endocrinology 2009, 150(3), 1078-83
  • Fast mapping of short sequences with mismatches, insertions and deletions using index structures.
    Hoffmann S, Otto C, Kurtz S, Sharma CM, Khaitovich P, Vogel J, Stadler PF, Hackermüller J
    PLoS Comput Biol 2009, 5(9), e1000502
  • Jena Centre for Systems Biology of Ageing - JenAge.
    Hühne R, Thalheim T, Wagner K, Sühnel J
    2009, URL
  • Control of metabolic homeostasis by stress signaling is mediated by the lipocalin NLaz.
    Hull-Thompson J, Muffat J, Sanchez D, Walker DW, Benzer S, Ganfornina MD, Jasper H
    PLoS Genet 2009, 5(4), e1000460
  • In silico study of kinetochore control, amplification, and inhibition effects in MCC assembly.
    Ibrahim B, Schmitt E, Dittrich P, Diekmann S
    Biosystems 2009, 95(1), 35-50
  • JNK signaling in insulin-producing cells is required for adaptive responses to stress in Drosophila.
    Karpac J, Hull-Thompson J, Falleur M, Jasper H
    Aging Cell 2009, 8(3), 288-95
  • Insulin and JNK: optimizing metabolic homeostasis and lifespan.
    Karpac J, Jasper H
    Trends Endocrinol Metab 2009, 20(3), 100-6
  • A phosphorylation-acetylation switch regulates STAT1 signaling.
    Krämer OH, Knauer SK, Greiner G, Jandt E, Reichardt S, Gührs KH, Stauber RH, Böhmer FD, Heinzel T
    Genes Dev 2009, 23(2), 223-35
  • Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy.
    Kurth I, Pamminger T, Hennings JC, Soehendra D, Huebner AK, Rotthier A, Baets J, Senderek J, Topaloglu H, Farrell SA, Nürnberg G, Nürnberg P, De Jonghe P, Gal A, Kaether C, Timmerman V, Hübner CA
    Nat Genet 2009, 41(11), 1179-81
  • Evidence for human microRNA-offset RNAs in small RNA sequencing data.
    Langenberger D, Bermudez-Santana C, Hertel J, Hoffmann S, Khaitovich P, Stadler PF
    Bioinformatics 2009, 25(18), 2298-301
  • PI3Kgamma controls oxidative bursts in neutrophils via interactions with PKCalpha and p47phox.
    Lehmann K, Müller JP, Schlott B, Skroblin P, Barz D, Norgauer J, Wetzker R
    Biochem J 2009, 419(3), 603-10
  • The role of localization in the operation of the mitotic spindle assembly checkpoint.
    Lohel M, Ibrahim B, Diekmann S, Dittrich P
    Cell Cycle 2009, 8(16), 2650-60
  • Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool.
    Loizou JI, Oser G, Shukla V, Sawan C, Murr R, Wang ZQ, Trumpp A, Herceg Z
    J Immunol 2009, 183(10), 6422-31
  • Disruption of poly(ADP-ribose) homeostasis affects spermiogenesis and sperm chromatin integrity in mice.
    Meyer-Ficca ML, Lonchar J, Credidio C, Ihara M, Li Y, Wang ZQ, Meyer RG
    Biol Reprod 2009, 81(1), 46-55
  • Proapoptotic protein Siva binds to the muscle protein telethonin in cardiomyocytes during coxsackieviral infection.
    Mihatsch K, Nestler M, Saluz HP, Henke A, Munder T
    Cardiovasc Res 2009, 81(1), 108-15
  • Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential.
    Min W, Wang ZQ
    Front Biosci 2009, 14, 1619-26
  • Analysis of hypertrophic thyrotrophs in pituitaries of athyroid Pax8-/- mice.
    Mittag J, Friedrichsen S, Strube A, Heuer H, Bauer K
    Endocrinology 2009, 150(9), 4443-9
  • Identification of heparin-binding sites in proteins by selective labeling.
    Ori A, Free P, Courty J, Wilkinson MC, Fernig DG
    Mol Cell Proteomics 2009, 8(10), 2256-65
  • Conditional inactivation of glucocorticoid receptor gene in dopamine-beta-hydroxylase cells impairs chromaffin cell survival.
    Parlato R, Otto C, Tuckermann J, Stotz S, Kaden S, Gröne HJ, Unsicker K, Schütz G
    Endocrinology 2009, 150(4), 1775-81
  • 10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H, Schmidt P, Böhm KJ, Baasner S, Müller K, Unger E, Gerlach M, Günther EG
    J Med Chem 2009, 52(5), 1284-94
  • High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research.
    Reichwald K, Lauber C, Nanda I, Kirschner J, Hartmann N, Schories S, Gausmann U, Taudien S, Schilhabel MB, Szafranski K, Glöckner G, Schmid M, Cellerino A, Schartl M, Englert C, Platzer M
    Genome Biol 2009, 10(2), R16
  • Telomere dysfunction and DNA damage checkpoints in diseases and cancer of the gastrointestinal tract.
    Rudolph KL, Hartmann D, Opitz OG
    Gastroenterology 2009, 137(3), 754-62
  • Elektronenmikroskopie an Alzheimer-Fibrillen.
    Sachse C, Grigorieff N, Fändrich M
    Bioforum 2009, 32(2), 26
  • Sequence assembly.
    Scheibye-Alsing K, Hoffmann S, Frankel A, Jensen P, Stadler PF, Mang Y, Tommerup N, Gilchrist MJ, Nygård AB, Cirera S, Jørgensen CB, Fredholm M, Gorodkin J
    Comput Biol Chem 2009, 33(2), 121-36
  • The ether-cleaving methyltransferase system of the strict anaerobe Acetobacterium dehalogenans: analysis and expression of the encoding genes.
    Schilhabel A, Studenik S, Vödisch M, Kreher S, Schlott B, Pierik AJ, Pierik AY, Diekert G
    J Bacteriol 2009, 191(2), 588-99
  • Small polydispersed circular DNA contains strains of mobile genetic elements and occurs more frequently in permanent cell lines of malignant tumors than in normal lymphocytes.
    Schmidt H, Taubert H, Lange H, Kriese K, Schmitt WD, Hoffmann S, Bartel F, Hauptmann S
    Oncol Rep 2009, 22(2), 393-400
  • Comparison of Alzheimer Abeta(1-40) and Abeta(1-42) amyloid fibrils reveals similar protofilament structures.
    Schmidt M, Sachse C, Richter W, Xu C, Fändrich M, Grigorieff N
    Proc Natl Acad Sci U S A 2009, 106(47), 19813-8
  • Proteomic analysis of Legionella-containing phagosomes isolated from Dictyostelium.
    Shevchuk O, Batzilla C, Hägele S, Kusch H, Engelmann S, Hecker M, Haas A, Heuner K, Glöckner G, Steinert M
    Int J Med Microbiol 2009, 299(7), 489-508
  • WID, a novel negative regulator of the WNT signaling pathway, is important for kidney development.
    Shin Kim M, Kitagaki J, Bollig F, Englert C, Perantoni AO, Lee SB
    Dev Biol 2009, 331(2), 484
  • X chromosomal variation is associated with slow progression to AIDS in HIV-1-infected women.
    Siddiqui RA, Sauermann U, Altmüller J, Fritzer E, Nothnagel M, Dalibor N, Fellay J, Kaup FJ, Stahl-Hennig C, Nürnberg P, Krawczak M, Platzer M
    Am J Hum Genet 2009, 85(2), 228-39
  • Wound healing defect of Vav3-/- mice due to impaired {beta}2-integrin-dependent macrophage phagocytosis of apoptotic neutrophils.
    Sindrilaru A, Peters T, Schymeinsky J, Oreshkova T, Wang H, Gompf A, Mannella F, Wlaschek M, Sunderkötter C, Rudolph KL, Walzog B, Bustelo XR, Fischer KD, Scharffetter-Kochanek K
    Blood 2009, 113(21), 5266-76
  • Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development.
    Skouloudaki K, Puetz M, Simons M, Courbard JR, Boehlke C, Hartleben B, Engel C, Moeller MJ, Englert C, Bollig F, Schäfer T, Ramachandran H, Mlodzik M, Huber TB, Kuehn EW, Kim E, Kramer-Zucker A, Walz G
    Proc Natl Acad Sci U S A 2009, 106(21), 8579-84
  • Multilocus patterns of nucleotide diversity, population structure and linkage disequilibrium in Boechera stricta, a wild relative of Arabidopsis.
    Song BH, Windsor AJ, Schmid KJ, Ramos-Onsins S, Schranz ME, Heidel AJ, Mitchell-Olds T
    Genetics 2009, 181(3), 1021-33
  • Cell intrinsic and extrinsic mechanisms of stem cell aging depend on telomere status.
    Song Z, Ju Z, Rudolph KL
    Exp Gerontol 2009, 44(1-2), 75-82
  • Evolution of vault RNAs.
    Stadler PF, Chen JJL, Hackermüller J, Hoffmann S, Horn F, Khaitovich P, Kretzschmar AK, Mosig A, Prohaska SJ, Qi X, Schutt K, Ullmann K
    Mol Biol Evol 2009, 26(9), 1975-91
  • De novo 454 sequencing of barcoded BAC pools for comprehensive gene survey and genome analysis in the complex genome of barley.
    Steuernagel B, Taudien S, Gundlach H, Seidel M, Ariyadasa R, Schulte D, Petzold A, Felder M, Graner A, Scholz U, Mayer KFX, Platzer M, Stein N
    BMC Genomics 2009, 10, 547
  • Age-dependent remodelling of retinal circuitry.
    Terzibasi E, Calamusa M, Novelli E, Domenici L, Strettoi E, Cellerino A
    Neurobiol Aging 2009, 30(5), 819-28 published during change of institution
  • Telomeres and Aging, Cancer, and Hepatic Fibrosis
    Tillmann HL, Plentz RR, Lechel A, Rudolph KL
    In: The Liver: Biology and Pathobiology (edited by Irwin MA, Co-Editor AW, James B, David S, Nelson F, Harvey A, David C) 2009, 1105-1119, John Wiley and Sons L
  • Regulation of connexin gene expression during skeletal muscle regeneration in the adult rat.
    Trovato-Salinaro A, Belluardo N, Frinchi M, von Maltzahn J, Willecke K, Condorelli DF, Mudò G
    Am J Physiol Cell Physiol 2009, 296(3), C593-606
  • Calpain-mediated degradation of reversibly oxidized protein-tyrosine phosphatase 1B.
    Trümpler A, Schlott B, Herrlich P, Greer PA, Böhmer FD
    FEBS J 2009, 276(19), 5622-33
  • Mapping loci associated with tail color and sex determination in the short-lived fish Nothobranchius furzeri.
    Valenzano* DR, Kirschner* J, Kamber RA, Zhang E, Weber D, Cellerino A, Englert C, Platzer M, Reichwald K, Brunet A
    Genetics 2009, 183(4), 1385-5 * equal contribution
  • Role of telomere dysfunction in aging and its detection by biomarkers.
    von Figura G, Hartmann D, Song Z, Rudolph KL
    J Mol Med 2009, 87(12), 1165-71
  • [[Cancer and aging--biological mechanisms].
    von Figura G, Rudolph KL
    Onkologie 2009, 32 Suppl 3, 34-8
  • C-terminal tagging with eGFP yields new insights into expression of connexin45 but prevents rescue of embryonic lethal connexin45-deficient mice.
    von Maltzahn J, Kreuzberg MM, Matern G, Euwens C, Höher T, Wörsdörfer P, Willecke K
    Eur J Cell Biol 2009, 88(9), 481-94
  • Procolipase gene: no association with early-onset obesity or fat intake.
    Wermter AK, Scherag A, Holter K, Reichwald K, Lichtner P, Siegfried W, Blundell J, Lawton C, Whybrow S, Stubbs J, Arch JR, Meitinger T, Platzer M, Hinney A, Hebebrand J
    Obes Facts 2009, 2(1), 40-4
  • A whole-genome snapshot of 454 sequences exposes the composition of the barley genome and provides evidence for parallel evolution of genome size in wheat and barley.
    Wicker T, Taudien S, Houben A, Keller B, Graner A, Platzer M, Stein N
    Plant J 2009, 59(5), 712-22
  • Adapted Boolean network models for extracellular matrix formation.
    Wollbold J, Huber R, Pohlers D, Koczan D, Guthke R, Kinne RW, Gausmann U
    BMC Syst Biol 2009, 3, 77
  • Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis.
    Wüst S, Tischner D, John M, Tuckermann JP, Menzfeld C, Hanisch UK, van den Brandt J, Lühder F, Reichardt HM
    PLoS One 2009, 4(12), e8202
  • Short telomeres and prognosis of hypertension in a chinese population.
    Yang Z, Huang X, Jiang H, Zhang Y, Liu H, Qin C, Eisner GM, Jose PA, Jose P, Rudolph L, Ju Z
    Hypertension 2009, 53(4), 639-45
  • Keeping your senescent cells under control.
    Zender L, Rudolph KL
    Aging (Albany NY) 2009, 1(5), 438-41
  • Mutations/polymorphisms in the 55 kDa subunit of DNA polymerase epsilon in human colorectal cancer.
    Zhou Q, Talvinen K, Sundström J, Elzagheid A, Pospiech H, Syväoja JE, Collan Y
    Cancer Genomics Proteomics 2009, 6(6), 297-304

Publications 2008:

  • MRI evidence of white matter damage in a mouse model of Nijmegen breakage syndrome.
    Assaf Y, Galron R, Shapira I, Nitzan A, Blumenfeld-Katzir T, Solomon AS, Holdengreber V, Wang ZQ, Shiloh Y, Barzilai A
    Exp Neurol 2008, 209(1), 181-91
  • The heme oxygenase-carbon monoxide system: regulation and role in stress response and organ failure.
    Bauer M, Huse K, Settmacher U, Claus RA
    Intensive Care Med 2008, 34(4), 640-8
  • Glucocorticoid receptor is required for skin barrier competence.
    Bayo P, Sanchis A, Bravo A, Cascallana JL, Buder K, Tuckermann J, Schütz G, Pérez P
    Endocrinology 2008, 149(3), 1377-88
  • Transport of beads by several kinesin motors.
    Beeg J, Klumpp S, Dimova R, Gracià RS, Unger E, Lipowsky R
    Biophys J 2008, 94(2), 532-41
  • Structural robustness of metabolic networks with respect to multiple knockouts.
    Behre J, Wilhelm T, von Kamp A, Ruppin E, Schuster S
    J Theor Biol 2008, 252(3), 433-41
  • Understanding Nitrogen Limitation in Aurecoccus anophageferens (Pelagophyceae) trough cDNA and qRT-PCR analysis.
    Berg GM, Shrager J, Glöckner G, Arrigo KR, Grossman AR
    J Phycol 2008, 44(5), 1235-49
  • JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut.
    Biteau B, Hochmuth CE, Jasper H
    Cell Stem Cell 2008, 3(4), 442-55
  • Kinesin-driven transport in cell-free environment.
    Böhm KJ
    Cell Biol Int 2008, 32(5), 588-90
  • Opposing effects of dietary protein and sugar regulate a transcriptional target of Drosophila insulin-like peptide signaling.
    Buch S, Melcher C, Bauer M, Katzenberger J, Pankratz MJ
    Cell Metab 2008, 7(4), 321-32
  • Antifungal effects of ethyl pyruvate, ethyl lactate and butyl lactate on selected dermatophytes.
    Büsing K, Birkenmeier G, Huse K, Gruss S, Krüger M
    Mycoses 2008, 51(5), 365–436
  • Centromere anatomy in the multidrug-resistant pathogen Enterococcus faecium.
    Derome A, Hoischen C, Bussiek M, Grady R, Adamczyk M, Kedzierska B, Diekmann S, Barillà D, Hayes F
    Proc Natl Acad Sci U S A 2008, 105(6), 2151-6
  • Restriction to Fos family members of Trip6-dependent coactivation and glucocorticoid receptor-dependent trans-repression of activator protein-1.
    Diefenbacher M, Sekula S, Heilbock C, Maier JV, Litfin M, van Dam H, Castellazzi M, Herrlich P, Kassel O
    Mol Endocrinol 2008, 22(8), 1767-80
  • Cell-specific regulation of PTX3 by glucocorticoid hormones in hematopoietic and nonhematopoietic cells.
    Doni A, Mantovani G, Porta C, Tuckermann J, Reichardt HM, Kleiman A, Sironi M, Rubino L, Pasqualini F, Nebuloni M, Signorini S, Peri G, Sica A, Beck-Peccoz P, Bottazzi B, Mantovani A
    J Biol Chem 2008, 283(44), 29983-92
  • RelB-dependent stromal cells promote T-cell leukemogenesis.
    dos Santos NR, Williame M, Gachet S, Cormier F, Janin A, Weih D, Weih F, Ghysdael J
    PLoS One 2008, 3(7), e2555
  • Diagnosis and treatment of hepatocellular carcinoma.
    El-Serag HB, Marrero JA, Rudolph L, Reddy KR
    Gastroenterology 2008, 134(6), 1752-63
  • Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses.
    Ermolaeva MA, Michallet MC, Papadopoulou N, Utermöhlen O, Kranidioti K, Kollias G, Tschopp J, Pasparakis M
    Nat Immunol 2008, 9(9), 1037-46
  • Tumour suppressor menin is essential for development of the pancreatic endocrine cells.
    Fontanière S, Duvillié B, Scharfmann R, Carreira C, Wang ZQ, Zhang CX
    J Endocrinol 2008, 199(2), 287-98
  • A first glimpse at the transcriptome of Physarum polycephalum.
    Glöckner G, Golderer G, Werner-Felmayer G, Meyer S, Marwan W
    BMC Genomics 2008, 9, 6
  • Identification and characterization of a new conjugation/type IVA secretion system (trb/tra) of Legionella pneumophila Corby localized on two mobile genomic islands.
    Glöckner* G, Albert-Weissenberger* C, Weinmann E, Jacobi S, Schunder E, Steinert M, Hacker J, Heuner K
    Int J Med Microbiol 2008, 298(5-6), 411-28 * equal contribution
  • Autophagy in freshwater planarians.
    González-Estévez C
    In: Methods in Enzymology, Autophagy: Lower Eukaryotes and Non-Mammalian Systems, Part A (edited by Department oDG, Gene C, Institute oG, Queen's MC, University oN, United K) 2008, 451, 439-65, Elsevier BV, Amsterdam
  • The wave property of heavy molecules - its use in mass spectrometry.
    Greulich KO
    Angew Chem Int Ed Engl 2008, 47(42), 7990-1
  • Environmental conditions impinge on dragline silk protein composition.
    Guehrs KH, Schlott B, Grosse F, Weisshart K
    Insect Mol Biol 2008, 17(5), 553-64
  • Protection of vascular smooth muscle cells by over-expressed methionine sulphoxide reductase A: role of intracellular localization and substrate availability.
    Haenold R, Wassef R, Brot N, Neugebauer S, Leipold E, Heinemann SH, Hoshi T
    Free Radic Res 2008, 42(11-12), 978-88
  • Connexin45 is expressed in the juxtaglomerular apparatus and is involved in the regulation of renin secretion and blood pressure.
    Hanner F, von Maltzahn J, Maxeiner S, Toma I, Sipos A, Krüger O, Willecke K, Peti-Peterdi J
    Am J Physiol Regul Integr Comp Physiol 2008, 295(2), R371-80
  • Mitochondrial genome evolution in the social amoebae.
    Heidel AJ, Glöckner G
    Mol Biol Evol 2008, 25(7), 1440-50
  • Supreme EnLIGHTenment: damage recognition and signaling in the mammalian UV response.
    Herrlich P, Karin M, Weiss C
    Mol Cell 2008, 29(3), 279-90
  • Widespread and subtle: alternative splicing at short-distance tandem sites.
    Hiller M, Platzer M
    Trends Genet 2008, 24(5), 246-55
  • Selection against tandem splice sites affecting structured protein regions.
    Hiller M, Szafranski K, Huse K, Backofen R, Platzer M
    BMC Evol Biol 2008, 8, 89
  • Oncostatin M-induced and constitutive activation of the JAK2/STAT5/CIS pathway suppresses CCL1, but not CCL7 and CCL8, chemokine expression.
    Hintzen C, Haan C, Tuckermann JP, Heinrich PC, Hermanns HM
    J Immunol 2008, 181(10), 7341-9
  • HLA-DRB1*0401 and HLA-DRB1*0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis.
    Hoffmann S, Cepok S, Grummel V, Lehmann-Horn K, Hackermüller J, Stadler PF, Hartung HP, Berthele A, Deisenhammer F, Wassmuth R, Hemmer B
    Am J Hum Genet 2008, 83(2), 219-27
  • Escherichia coli low-copy-number plasmid R1 centromere parC forms a U-shaped complex with its binding protein ParR.
    Hoischen C, Bussiek M, Langowski J, Diekmann S
    Nucleic Acids Res 2008, 36(2), 607-15
  • Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane.
    Huber R, Hummert C, Gausmann U, Pohlers D, Koczan D, Guthke R, Kinne RW
    Arthritis Res Ther 2008, 10(4), R98
  • Two new bis-styryl compounds from Miliusa balansae.
    Huong DT, Van NTH, Kamperdick C, Anh NTH, Sung TV
    Z Naturforsch B 2008, 63b, 335-8
  • In-silico modeling of the mitotic spindle assembly checkpoint.
    Ibrahim B, Diekmann S, Schmitt E, Dittrich P
    PLoS One 2008, 3(2), e1555
  • Mad2 binding is not sufficient for complete Cdc20 sequestering in mitotic transition control (an in silico study).
    Ibrahim B, Dittrich P, Diekmann S, Schmitt E
    Biophys Chem 2008, 134(1-2), 93-100
  • SKNy worms and long life.
    Jasper H
    Cell 2008, 132(6), 915-6
  • Marsupial uncoupling protein 1 sheds light on the evolution of mammalian nonshivering thermogenesis.
    Jastroch M, Withers KW, Taudien S, Frappell PB, Helwig M, Fromme T, Hirschberg V, Heldmaier G, McAllan BM, Firth BT, Burmester T, Platzer M, Klingenspor M
    Physiol Genomics 2008, 32(2), 161-9
  • Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease.
    Jiang H, Schiffer E, Song Z, Wang J, Zürbig P, Thedieck K, Moes S, Bantel H, Saal N, Jantos J, Brecht M, Jenö P, Hall MN, Hager K, Manns MP, Hecker H, Ganser A, Döhner K, Bartke A, Meissner C, Mischak H, Ju Z, Rudolph KL
    Proc Natl Acad Sci U S A 2008, 105(32), 11299-304
  • The actinome of Dictyostelium discoideum in comparison to actins and actin-related proteins from other organisms.
    Joseph JM, Fey P, Ramalingam N, Liu XI, Rohlfs M, Noegel AA, Müller-Taubenberger A, Glöckner G, Schleicher M
    PLoS One 2008, 3(7), e2654
  • Telomere dysfunction and stem cell ageing.
    Ju Z, Lenhard Rudolph K, Rudolph L
    Biochimie 2008, 90(1), 24-32
  • Carbonyl reductase 1 is a predominant doxorubicin reductase in the human liver.
    Kassner N, Huse K, Martin HJ, Gödtel-Armbrust U, Metzger A, Meineke I, Brockmöller J, Klein K, Zanger UM, Maser E, Wojnowski L
    Drug Metab Dispos 2008, 36(10), 2113-20
  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.
    Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin LS, Choi A, Chu CT, Chung J, Clarke PGH, Clark RSB, Clarke SG, Clavé C, Cleveland JL, Codogno P, Colombo MI, Coto-Montes A, Cregg JM, Cuervo AM, Debnath J, Demarchi F, Dennis PB, Dennis PA, Deretic V, Devenish RJ, Di Sano F, Dice JF, Difiglia M, Dinesh-Kumar S, Distelhorst CW, Djavaheri-Mergny M, Dorsey FC, Dröge W, Dron M, Dunn WA, Duszenko M, Eissa NT, Elazar Z, Esclatine A, Eskelinen EL, Fésüs L, Finley KD, Fuentes JM, Fueyo J, Fujisaki K, Galliot B, Gao FB, Gewirtz DA, Gibson SB, Gohla A, Goldberg AL, Gonzalez R, González-Estévez C, Gorski S, Gottlieb RA, Häussinger D, He YW, Heidenreich K, Hill JA, Høyer-Hansen M, Hu X, Huang WP, Iwasaki A, Jäättelä M, Jackson WT, Jiang X, Jin S, Johansen T, Jung JU, Kadowaki M, Kang C, Kelekar A, Kessel DH, Kiel JAKW, Kim HP, Kimchi A, Kinsella TJ, Kiselyov K, Kitamoto K, Knecht E, Komatsu M, Kominami E, Kondo S, Kovács AL, Kroemer G, Kuan CY, Kumar R, Kundu M, Landry J, Laporte M, Le W, Lei HY, Lenardo MJ, Levine B, Lieberman A, Lim KL, Lin FC, Liou W, Liu LF, Lopez-Berestein G, López-Otín C, Lu B, Macleod KF, Malorni W, Martinet W, Matsuoka K, Mautner J, Meijer AJ, Meléndez A, Michels P, Miotto G, Mistiaen WP, Mizushima N, Mograbi B, Monastyrska I, Moore MN, Moreira PI, Moriyasu Y, Motyl T, Münz C, Murphy LO, Naqvi NI, Neufeld TP, Nishino I, Nixon RA, Noda T, Nürnberg B, Ogawa M, Oleinick NL, Olsen LJ, Ozpolat B, Paglin S, Palmer GE, Papassideri I, Parkes M, Perlmutter DH, Perry G, Piacentini M, Pinkas-Kramarski R, Prescott M, Proikas-Cezanne T, Raben N, Rami A, Reggiori F, Rohrer B, Rubinsztein DC, Ryan KM, Sadoshima J, Sakagami H, Sakai Y, Sandri M, Sasakawa C, Sass M, Schneider C, Seglen PO, Seleverstov O, Settleman J, Shacka JJ, Shapiro IM, Sibirny A, Silva-Zacarin ECM, Simon HU, Simone C, Simonsen A, Smith MA, Spanel-Borowski K, Srinivas V, Steeves M, Stenmark H, Stromhaug PE, Subauste CS, Sugimoto S, Sulzer D, Suzuki T, Swanson MS, Tabas I, Takeshita F, Talbot NJ, Tallóczy Z, Tanaka K, Tanaka K, Tanida I, Taylor GS, Taylor JP, Terman A, Tettamanti G, Thompson CB, Thumm M, Tolkovsky AM, Tooze SA, Truant R, Tumanovska LV, Uchiyama Y, Ueno T, Uzcátegui NL, van der Klei I, Vaquero EC, Vellai T, Vogel MW, Wang HG, Webster P, Wiley JW, Xi Z, Xiao G, Yahalom J, Yang JM, Yap G, Yin XM, Yoshimori T, Yu L, Yue Z, Yuzaki M, Zabirnyk O, Zheng X, Zhu X, Deter RL
    Autophagy 2008, 4(2), 151-75
  • Combined kinetic osmometry and pyrometric microcalorimetry on protein solutions: Setup and data evaluation.
    Klupsch T, Walter A, Mühlig P, Hilgenfeld R
    Colloid Surface A 2008, 318(1-3), 24-44
  • A new class of ice-binding proteins discovered in a salt-stress-induced cDNA library of the psychrophilic diatom Fragilariopsis cylindrus (Bacillariophyceae).
    Krell A, Beszteri B, Dieckmann G, Glöckner G, Valentin K, Mock T
    Eur J Phycol 2008, 43, 423-33
  • Rho GTPase and Wnt signaling pathways in hepatocarcinogenesis.
    Lechel A, Rudolph KL
    Gastroenterology 2008, 134(3), 875-8
  • Differential RelA- and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts.
    Lovas A, Radke D, Albrecht D, Yilmaz ZB, Möller U, Habenicht AJR, Weih F
    BMC Genomics 2008, 9, 606
  • Synthesis of the phosphinic analogue of thyrotropin releasing hormone.
    Matziari M, Bauer K, Dive V, Yiotakis A
    J Org Chem 2008, 73(21), 8591-3
  • Density functional study of adenine tetrads with N6-H6...N3 hydrogen bonds.
    Meyer M, Sühnel J
    J Phys Chem A 2008, 112(18), 4336-41
  • TRADD protein is an essential component of the RIG-like helicase antiviral pathway.
    Michallet MC, Meylan E, Ermolaeva MA, Vazquez J, Rebsamen M, Curran J, Poeck H, Bscheider M, Hartmann G, König M, Kalinke U, Pasparakis M, Tschopp J
    Immunity 2008, 28(5), 651-61
  • Non-conservative homologous recombination in human B lymphocytes is promoted by activation-induced cytidine deaminase and transcription.
    Mierau M, Drexler GA, Kutzera A, Braunschmidt K, Ellwart J, Eckardt-Schupp F, Fritz E, Bachl J, Jungnickel B
    Nucleic Acids Res 2008, 36(17), 5591-601
  • Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa.
    Müller* TD, Reichwald* K, Brönner G, Kirschner J, Nguyen TT, Scherag A, Herzog W, Herpertz-Dahlmann B, Lichtner P, Meitinger T, Platzer M, Schäfer H, Hebebrand J, Hinney A
    Child Adolesc Psychiatry Ment Health 2008, 2(1), 33 * equal contribution
  • Determining the influence of telomere dysfunction and DNA damage on stem and progenitor cell aging: what markers can we use?
    Nalapareddy K, Jiang H, Guachalla Gutierrez LM, Rudolph KL
    Exp Gerontol 2008, 43(11), 998-1004
  • Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection.
    Nguyen T, Ishida K, Jenke-Kodama H, Dittmann E, Gurgui C, Hochmuth T, Taudien S, Platzer M, Hertweck C, Piel J
    Nat Biotechnol 2008, 26(2), 225-33
  • 14-3-3 Epsilon antagonizes FoxO to control growth, apoptosis and longevity in Drosophila.
    Nielsen MD, Luo X, Biteau B, Syverson K, Jasper H
    Aging Cell 2008, 7(5), 688-99
  • Chromatophore genome sequence of Paulinella sheds light on acquisition of photosynthesis by eukaryotes.
    Nowack ECM, Melkonian M, Glöckner G
    Curr Biol 2008, 18(6), 410-18
  • The solution structure of the amino-terminal domain of human DNA polymerase epsilon subunit B is homologous to C-domains of AAA+ proteins.
    Nuutinen T, Tossavainen H, Fredriksson K, Pirilä P, Permi P, Pospiech H, Syvaoja JE
    Nucleic Acids Res 2008, 36(15), 5102-10
  • Conformational signatures of 13C chemical shifts in RNA ribose.
    Ohlenschläger O, Haumann S, Ramachandran R, Görlach M
    J Biomol NMR 2008, 42(2), 139-42
  • The heparanome and regulation of cell function: structures, functions and challenges.
    Ori A, Wilkinson MC, Fernig DG
    Front Biosci 2008, 13, 4309-38
  • Deficiency in Poly(ADP-ribose) Polymerase-1 (PARP-1) Accelerates Aging and Spontaneous Carcinogenesis in Mice.
    Piskunova TS, Yurova MN, Ovsyannikov AI, Semenchenko AV, Zabezhinski MA, Popovich IG, Wang ZQ, Anisimov VN
    Curr Gerontol Geriatr Res 2008, 754190
  • Critical role of macrophages in glucocorticoid driven vascular calcification in a mouse-model of atherosclerosis.
    Preusch MR, Rattazzi M, Albrecht C, Merle U, Tuckermann J, Schütz G, Blessing E, Zoppellaro G, Pauletto P, Krempien R, Rosenfeld ME, Katus HA, Bea F
    Arterioscler Thromb Vasc Biol 2008, 28(12), 2158-64
  • CYP3 phylogenomics: evidence for positive selection of CYP3A4 and CYP3A7.
    Qiu H, Taudien S, Herlyn H, Schmitz J, Zhou Y, Chen G, Roberto R, Rocchi M, Platzer M, Wojnowski L
    Pharmacogenet Genomics 2008, 18(1), 53-66
  • Mechanisms of Stem Cell Ageing
    Rudolph KL (ed)
    Book series: Telomeres and Telomerase in Ageing, Disease, and Cancer 2008, Springer
  • Mhc class I haplotypes associated with survival time in simian immunodeficiency virus (SIV)-infected rhesus macaques.
    Sauermann U, Siddiqui R, Suh YS, Platzer M, Leuchte N, Meyer H, Mätz-Rensing K, Stoiber H, Nürnberg P, Hunsmann G, Stahl-Hennig C, Krawczak M
    Genes Immun 2008, 9(1), 69-80
  • Characterization of the interaction between the human DNA topoisomerase IIbeta-binding protein 1 (TopBP1) and the cell division cycle 45 (Cdc45) protein.
    Schmidt U, Wollmann Y, Franke C, Grosse F, Saluz HP, Hänel F
    Biochem J 2008, 409(1), 169-77
  • Solution structure of stem-loop alpha of the hepatitis B virus post-transcriptional regulatory element.
    Schwalbe M, Ohlenschläger O, Marchanka A, Ramachandran R, Häfner S, Heise T, Görlach M
    Nucleic Acids Res 2008, 36(5), 1681-9
  • A mutually exclusive alternative exon of slo1 codes for a neuronal BK channel with altered function.
    Soom M, Gessner G, Heuer H, Hoshi T, Heinemann SH
    Channels 2008, 2(4), 278-82
  • SNP and haplotype mapping for genetic analysis in the rat.
    STAR Consortium, Saar K, Beck A, Bihoreau MT, Birney E, Brocklebank D, Chen Y, Cuppen E, Demonchy S, Dopazo J, Flicek P, Foglio M, Fujiyama A, Gut IG, Gauguier D, Guigo R, Guryev V, Heinig M, Hummel O, Jahn N, Klages S, Kren V, Kube M, Kuhl H, Kuramoto T, Kuroki Y, Lechner D, Lee YA, Lopez-Bigas N, Lathrop GM, Mashimo T, Medina I, Mott R, Patone G, Perrier-Cornet JA, Platzer M, Pravenec M, Reinhardt R, Sakaki Y, Schilhabel M, Schulz H, Serikawa T, Shikhagaie M, Tatsumoto S, Taudien S, Toyoda A, Voigt B, Zelenika D, Zimdahl H, Hubner N
    Nat Genet 2008, 40(5), 560-6
  • Hydrophobic interaction of organic chemicals with microtubule assembly in vitro.
    Stoiber T, Unger E, Dorn SB, Degen GH, Bolt HM
    Arch Toxicol 2008, 82(9), 601-6
  • The elongation phase of the eukaryotic DNA replication.
    Syväoja JE, Pospiech H
    In: DNA Replication, Repair and Recombination at the Crossroad Between Genome Integrity and Genome Instability: A Biochemical Perspective (edited by Maga G, Hübscher U, Villani G, Baldacci G) 2008, 21-40, Research Signpost, Kerala
  • Establishment of immortalized multipotent hematopoietic progenitor cell lines by retroviral-mediated gene transfer of beta-catenin.
    Templin C, Kotlarz D, Rathinam C, Rudolph C, Schätzlein S, Ramireddy K, Rudolph KL, Schlegelberger B, Klein C, Drexler H
    Exp Hematol 2008, 36(2), 204-15
  • Large differences in aging phenotype between strains of the short-lived annual fish Nothobranchius furzeri.
    Terzibasi* E, Valenzano* DR, Benedetti M, Roncaglia P, Cattaneo A, Domenici L, Cellerino A
    PLoS One 2008, 3(12), e3866 * equal contribution
  • Autophagy in invertebrates: insights into development, regeneration and body remodeling.
    Tettamanti G, Saló E, González-Estévez C, Felix DA, Grimaldi A, de Eguileor M
    Curr Pharm Des 2008, 14(2), 116-25
  • Transcriptional Regulation.
    Tuckermann JP, Herrlich P
    In: Encyclopedia of Molecular Pharmacology (edited by Rosenthal W) 2008, 1224-9, Springer New York, New Y
  • Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdominance in humans.
    Wermter AK, Scherag A, Meyre D, Reichwald K, Durand E, Nguyen TT, Koberwitz K, Lichtner P, Meitinger T, Schäfer H, Hinney A, Froguel P, Hebebrand J, Brönner G
    Eur J Hum Genet 2008, 16(9), 1126-34
  • Connexin expression and functional analysis of gap junctional communication in mouse embryonic stem cells.
    Wörsdörfer P, Maxeiner S, Markopoulos C, Kirfel G, Wulf V, Auth T, Urschel S, von Maltzahn J, Willecke K
    Stem Cells 2008, 26(2), 431-9
  • Peripheral T cells are the therapeutic targets of glucocorticoids in experimental autoimmune encephalomyelitis.
    Wüst S, van den Brandt J, Tischner D, Kleiman A, Tuckermann JP, Gold R, Lühder F, Reichardt HM
    J Immunol 2008, 180(12), 8434-43
  • Genomic changes of the 55 kDa subunit of DNA polymerase epsilon in human breast cancer.
    Zhou Q, Effati R, Talvinen K, Pospiech H, Syväoja JE, Collan Y
    Cancer Genomics Proteomics 2008, 5(5), 287-92

Publications 2007:

  • Expression levels of 63 p53-related genes add up to similar values in 24 different tissues and are unified in cancer.
    Altenberg B, Rapp A, Schmitt E, Greulich KO
    Genomics 2007, 90(6), 661-73
  • Distinct roles of lymphotoxin-beta signaling and the homeodomain transcription factor Nkx2.3 in the ontogeny of endothelial compartments in spleen.
    Balogh P, Balázs M, Czömpöly T, Weih DS, Arnold HH, Weih F
    Cell Tissue Res 2007, 328(3), 473-86
  • Laser Manipulation of Cells and Tissues.
    Berns MW, Greulich KO (eds)
    Book series: Methods in Cell Biology 2007, 82, pages 792. Academic Press, Lond
  • Antiproliferative activity of CCN3: involvement of the C-terminal module and post-translational regulation.
    Bleau AM, Planque N, Lazar N, Zambelli D, Ori A, Quan T, Fisher G, Scotlandi K, Perbal B
    J Cell Biochem 2007, 101(6), 1475-91
  • Posttranscriptional expression regulation: what determines translation rates?
    Brockmann R, Beyer A, Heinisch JJ, Wilhelm T
    PLoS Comput Biol 2007, 3(3), e57
  • Organisation of nucleosomal arrays reconstituted with repetitive African green monkey alpha-satellite DNA as analysed by atomic force microscopy.
    Bussiek M, Müller G, Waldeck W, Diekmann S, Langowski J
    Eur Biophys J 2007, 37(1), 81-93
  • Specific alterations of tyrosine hydroxylase immunopositive cells in the retina of NT-4 knock out mice.
    Calamusa M, Pattabiraman PP, Pozdeyev N, Iuvone PM, Cellerino A, Domenici L
    Vision Res 2007, 47(11), 1523-36 published during change of institution
  • Analysis of genetic variants of the poly(ADP-ribose) polymerase-1 gene in breast cancer in French patients.
    Cao WH, Wang X, Frappart L, Rigal D, Wang ZQ, Shen Y, Tong WM
    Mutat Res 2007, 632(1-2), 20-8 published during change of institution
  • Neurophysiological correlates for the perception of facial sexual dimorphism.
    Cellerino A, Borghetti D, Valenzano DR, Tartarelli G, Mennucci A, Murri L, Sartucci F
    Brain Res Bull 2007, 71(5), 515-22 published during change of institution
  • Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.
    Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, Wang C, Buer J, Lee HW, von Zglinicki T, Ganser A, Schirmacher P, Nakauchi H, Rudolph KL
    Nat Genet 2007, 39(1), 99-105
  • Role of poly(ADP-ribose) glycohydrolase in the development of inflammatory bowel disease in mice.
    Cuzzocrea S, Mazzon E, Genovese T, Crisafulli C, Min WK, Di Paola R, Muià C, Li JH, Malleo G, Xu W, Massuda E, Esposito E, Zhang J, Wang ZQ
    Free Radic Biol Med 2007, 42(1), 90-105 published during change of institution
  • Mapping human genetic ancestry.
    Ebersberger I, Galgoczy P, Taudien S, Taenzer S, Platzer M, von Haeseler A
    Mol Biol Evol 2007, 24(10), 2266-76
  • Hepatocellular carcinoma: epidemiology and molecular carcinogenesis.
    El-Serag HB, Rudolph KL
    Gastroenterology 2007, 132(7), 2557-76
  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
    ENCODE Project Consortium
    Nature 2007, 447(7146), 799–816
  • On the structural definition of amyloid fibrils and other polypeptide aggregates.
    Fändrich M
    Cell Mol Life Sci 2007, 64(16), 2066-78
  • Absolute correlation between lag time and growth rate in the spontaneous formation of several amyloid-like aggregates and fibrils.
    Fändrich M
    J Mol Biol 2007, 365(5), 1266-70
  • The TATA-binding protein regulates maternal mRNA degradation and differential zygotic transcription in zebrafish.
    Ferg M, Sanges R, Gehrig J, Kiss J, Bauer M, Lovas A, Szabo M, Yang L, Straehle U, Pankratz MJ, Olasz F, Stupka E, Müller F
    EMBO J 2007, 26(17), 3945-56
  • Widespread occurrence and genomic context of unusually small polyketide synthase genes in microbial consortia associated with marine sponges.
    Fieseler L, Hentschel U, Grozdanov L, Schirmer A, Wen G, Platzer M, Hrvatin S, Butzke D, Zimmermann K, Piel J
    Appl Environ Microbiol 2007, 73(7), 2144-55
  • Systematic association mapping identifies NELL1 as a novel IBD disease gene.
    Franke A, Hampe J, Rosenstiel P, Becker C, Wagner F, Häsler R, Little RD, Huse K, Ruether A, Balschun T, Wittig M, Elsharawy A, Mayr G, Albrecht M, Prescott NJ, Onnie CM, Fournier H, Keith T, Radelof U, Platzer M, Mathew CG, Stoll M, Krawczak M, Nürnberg P, Schreiber S
    PLoS One 2007, 2(1), e691
  • Skin inflammation in RelB(-/-) mice leads to defective immunity and impaired clearance of vaccinia virus.
    Freyschmidt EJ, Mathias CB, MacArthur DH, Laouar A, Narasimhaswamy M, Weih F, Oettgen HC
    J Allergy Clin Immunol 2007, 119(3), 671-9
  • Mutation screen and association studies in the diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13.
    Friedel S, Reichwald K, Scherag A, Brumm H, Wermter AK, Fries HR, Koberwitz K, Wabitsch M, Meitinger T, Platzer M, Biebermann H, Hinney A, Hebebrand J
    BMC Genet 2007, 8, 17
  • Chicken ovalbumin upstream promoter transcription factor II regulates uncoupling protein 3 gene transcription in Phodopus sungorus.
    Fromme T, Reichwald K, Platzer M, Li XS, Klingenspor M
    BMC Mol Biol 2007, 8, 1
  • Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase.
    Gao H, Coyle DL, Meyer-Ficca ML, Meyer RG, Jacobson EL, Wang ZQ, Jacobson MK
    Exp Cell Res 2007, 313(5), 984-96 published during change of institution
  • Identification of molecular compounds critical to Alzheimer's-like plaque formation.
    Gellermann* GP, Ullrich* K, Unger C, Fändrich M, Sauter S, Diekmann S
    J Neurosci Res 2007, 85(9), 2037-44 * equal contribution
  • Gtdap-1 promotes autophagy and is required for planarian remodeling during regeneration and starvation.
    González-Estévez C, Felix DA, Aboobaker AA, Saló E
    Proc Natl Acad Sci U S A 2007, 104(33), 13373-8
  • Gtdap-1 and the role of autophagy during planarian regeneration and starvation.
    González-Estévez C, Felix DA, Aboobaker AA, Saló E
    Autophagy 2007, 3(6), 640-2
  • Practical aspects of working with laser microbeams and optical tweezers: data and equations.
    Greulich KO
    In: Laser Manipulation of Cells and Tissues (edited by Berns MW, Greulich KO), Methods in Cell Biology 2007, 82, 735-743, Academic Press, London
  • Selected applications of laser scissors and tweezers and new applications in heart research.
    Greulich KO
    In: Laser Manipulation of Cells and Tissues (edited by Berns MW, Greulich KO), Methods in Cell Biology 2007, 82, 59-80, Academic Press, London
  • Single photons cannot be extracted from the light of multi-atom light sources.
    Greulich KO
    In: The Nature of Light: What Are Photons?, Theoretical Formulations (edited by Roychoudhuri C, Kracklauer AF, Creath K), Proceedings of SPIE 2007, 6664, 66640B, SPIE Press, Bellingham,
  • Sergej Stepanovich Tschachotin: experimental cytologist and political critic (1883-1973).
    Greulich KO, Khodjakov A, Vogt A, Berns MW
    In: Laser Manipulation of Cells and Tissues (edited by Berns MW, Greulich KO), Methods in Cell Biology 2007, 82, 723-734, Academic Press, London
  • Biologie der Alterungsprozesse.
    Grosse F
    In: Grundwissen Medizin des Alterns und des alten Menschen, Querschnittsbereich 7 (edited by Wedding U, Pientka L, Höffken K) 2007, 26-33, Hans Huber, Bern
  • Imaging of self-assembled tubulin polymorphs used as metallization templates.
    Habicht W, Behrens S, Böhm KJ, Dinjus E
    J Phys Conf Ser 2007, 61, 374-8
  • FESEM/EDX and AFM assisted Characterization of Tubulin Derivatives used for Template-directed Metallization.
    Habicht W, Behrens S, Böhm KJ, Dinjus E
    Microsc Microanal 2007, 13(Suppl 2), 670-1
  • A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.
    Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, Albrecht M, Mayr G, De La Vega FM, Briggs J, Günther S, Prescott NJ, Onnie CM, Häsler R, Sipos B, Fölsch UR, Lengauer T, Platzer M, Mathew CG, Krawczak M, Schreiber S
    Nat Genet 2007, 39(2), 207-11 listed among the "most most frequently cited publications 2007-2010 in Human Genetics" in Laborjournal 12/2013
  • In vitro chemosensitivity of freshly explanted tumor cells to pemetrexed is correlated with target gene expression.
    Hanauske AR, Eismann U, Oberschmidt O, Pospisil H, Hoffmann S, Hanauske-Abel H, Ma D, Chen V, Paoletti P, Niyikiza C
    Invest New Drugs 2007, 25(5), 417-23
  • The importance of thyroid hormone transporters for brain development and function.
    Heuer H
    Best Pract Res Clin Endocrinol Metab 2007, 21(2), 265-76
  • TassDB: a database of alternative tandem splice sites.
    Hiller M, Nikolajewa S, Huse K, Szafranski K, Rosenstiel P, Schuster S, Backofen R, Platzer M
    Nucleic Acids Res 2007, 35, D188-92
  • A comparative view at comprehensive information resources on three-dimensional structures of biological macro-molecules.
    Hühne R, Koch FT, Sühnel J
    Brief Funct Genomic Proteomic 2007, 6(3), 220-39
  • Stochastic effects in a compartmental model for mitotic checkpoint regulation.
    Ibrahim B, Dittrich P, Diekmann S, Schmitt E
    J Integr Bioinform 2007, 4(3), 66
  • Expression profiling of Dexamethasone-treated primary chondrocytes identifies targets of glucocorticoid signalling in endochondral bone development.
    James CG, Ulici V, Tuckermann J, Underhill TM, Beier F
    BMC Genomics 2007, 8, 205
  • Telomere shortening and ageing.
    Jiang H, Ju Z, Rudolph KL
    Z Gerontol Geriatr 2007, 40(5), 314-24
  • A dual role of p21 in stem cell aging.
    Ju Z, Choudhury AR, Rudolph KL
    Ann N Y Acad Sci 2007, 1100, 333-44
  • Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment.
    Ju Z, Jiang H, Jaworski M, Rathinam C, Gompf A, Klein C, Trumpp A, Rudolph KL
    Nat Med 2007, 13(6), 742-7
  • Haploinsufficiency of poly(ADP-ribose) polymerase-1-mediated poly(ADP-ribosyl)ation for centrosome duplication.
    Kanai M, Tong WM, Wang ZQ, Miwa M
    Biochem Biophys Res Commun 2007, 359(3), 426-30
  • Crosstalk between the glucocorticoid receptor and other transcription factors: molecular aspects.
    Kassel O, Herrlich P
    Mol Cell Endocrinol 2007, 275(1-2), 13-29
  • Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain.
    Keil C, Maskos K, Than M, Hoopes JT, Huber R, Tan F, Deddish PA, Erdös EG, Skidgel RA, Bode W
    J Mol Biol 2007, 366(2), 504-16 published during change of institution
  • Glucocorticoid receptor action in beneficial and side effects of steroid therapy: lessons from conditional knockout mice.
    Kleiman A, Tuckermann JP
    Mol Cell Endocrinol 2007, 275(1-2), 98-108
  • Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease.
    Lechel A, Holstege H, Begus Y, Schienke A, Kamino K, Lehmann U, Kubicka S, Schirmacher P, Jonkers J, Rudolph KL
    Gastroenterology 2007, 132(4), 1465-75
  • Foxo and Fos regulate the decision between cell death and survival in response to UV irradiation.
    Luo X, Puig O, Hyun J, Bohmann D, Jasper H
    EMBO J 2007, 26(2), 380-90
  • Dual specificity phosphatase 1 knockout mice show enhanced susceptibility to anaphylaxis but are sensitive to glucocorticoids.
    Maier JV, Brema S, Tuckermann J, Herzer U, Klein M, Stassen M, Moorthy A, Cato ACB
    Mol Endocrinol 2007, 21(11), 2663-71
  • Endogenous transforming growth factor beta 1 suppresses inflammation and promotes survival in adult CNS.
    Makwana M, Jones LL, Cuthill D, Heuer H, Bohatschek M, Hristova M, Friedrichsen S, Ormsby I, Bueringer D, Koppius A, Bauer K, Doetschman T, Raivich G
    J Neurosci 2007, 27(42), 11201-13
  • The ancestor of the Paulinella chromatophore obtained a carboxysomal operon by horizontal gene transfer from a Nitrococcus-like gamma-proteobacterium.
    Marin B, Nowack ECM, Glöckner G, Melkonian M
    BMC Evol Biol 2007, 7, 85
  • Density functional study of isoguanine tetrad and pentad sandwich complexes with alkali metal ions.
    Meyer M, Steinke T, Sühnel J
    J Mol Model 2007, 13(2), 335-45
  • Expression and thyroid hormone regulation of annexins in the anterior pituitary.
    Mittag J, Oehr W, Heuer H, Hämäläinen T, Brachvogel B, Pöschl E, Bauer K
    J Endocrinol 2007, 195(3), 385-92
  • Rotational behavior of erythrocytes in optical trap: revisited by confocal fluorescence microscopy.
    Mohanty K, Mohanty S, Monajembashi S, Greulich KO
    In: Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V, Optical Manipulation (edited by Farkas DL, Leif RC, Nicolau DV), Proceedings of SPIE 2007, 6441, 644111, SPIE Press, Bellingham,
  • Orientation of erythrocytes in optical trap revealed by confocal fluorescence microscopy.
    Mohanty K, Mohanty S, Monajembashi S, Greulich KO
    J Biomed Opt 2007, 12(6), 060506
  • Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac.
    Morrison H, Sperka T, Manent J, Giovannini M, Ponta H, Herrlich P
    Cancer Res 2007, 67(2), 520-7
  • No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents.
    Müller TD, Reichwald K, Wermter AK, Brönner G, Nguyen TT, Friedel S, Koberwitz K, Engeli S, Lichtner P, Meitinger T, Schäfer H, Hebebrand J, Hinney A
    Mol Genet Metab 2007, 90(4), 429-34
  • BioBayesNet: a web server for feature extraction and Bayesian network modeling of biological sequence data.
    Nikolajewa S, Pudimat R, Hiller M, Platzer M, Backofen R
    Nucleic Acids Res 2007, 35, W688-93
  • Control of liver cell proliferation
    Nisar PM, Rudolph KL
    In: Textbook of Hepatology, From Basic Science to Clinical Practice (edited by Juan R, Jean-Pierre B, Andres B, Juerg R, Mario R) 2007, 2.5.1, John Wiley and Sons Ltd
  • Hepatocyte growth factor-induced Ras activation requires ERM proteins linked to both CD44v6 and F-actin.
    Orian-Rousseau* V, Morrison* H, Matzke A, Kastilan T, Pace G, Herrlich P, Ponta H
    Mol Biol Cell 2007, 18(1), 76-83 * equal contribution, published during change of institution
  • The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis.
    Osterloh* L, von Eyss* B, Schmit F, Rein L, Hübner D, Samans B, Hauser S, Gaubatz S
    EMBO J 2007, 26(1), 144-57 * equal contribution
  • Endosymbiont-dependent host reproduction maintains bacterial-fungal mutualism.
    Partida-Martinez LP, Monajembashi S, Greulich KO, Hertweck C
    Curr Biol 2007, 17(9), 773-7
  • The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros.
    Perner B, Englert C, Bollig F
    Dev Biol 2007, 309(1), 87-96
  • A novel Dps-type protein from insect gut bacteria catalyses hydrolysis and synthesis of N-acyl amino acids.
    Ping L, Büchler R, Mithöfer A, Svatos A, Spiteller D, Dettner K, Gmeiner S, Piel J, Schlott B, Boland W
    Environ Microbiol 2007, 9(6), 1572-83
  • Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis.
    Plentz RR, Park YN, Lechel A, Kim H, Nellessen F, Langkopf BHE, Wilkens L, Destro A, Fiamengo B, Manns MP, Roncalli M, Rudolph KL
    Hepatology 2007, 45(4), 968-76
  • Constitutive upregulation of the transforming growth factor-beta pathway in rheumatoid arthritis synovial fibroblasts.
    Pohlers D, Beyer A, Koczan D, Wilhelm T, Thiesen HJ, Kinne RW
    Arthritis Res Ther 2007, 9(3), R59
  • Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia.
    Roell W, Lewalter T, Sasse P, Tallini YN, Choi BR, Breitbach M, Doran R, Becher UM, Hwang SM, Bostani T, von Maltzahn J, Hofmann A, Reining S, Eiberger B, Gabris B, Pfeifer A, Welz A, Willecke K, Salama G, Schrickel JW, Kotlikoff MI, Fleischmann BK
    Nature 2007, 450(7171), 819-24
  • GenColors: annotation and comparative genomics of prokaryotes made easy.
    Romualdi A, Felder M, Rose D, Gausmann U, Schilhabel M, Glöckner G, Platzer M, Sühnel J
    Methods Mol Biol 2007, 395, 75-96
  • Functional characterization of two novel 5' untranslated exons reveals a complex regulation of NOD2 protein expression.
    Rosenstiel* P, Huse* K, Franke A, Hampe J, Reichwald K, Platzer C, Roberts RG, Mathew CG, Platzer M, Schreiber S
    BMC Genomics 2007, 8, 472 * equal contribution
  • Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice.
    Schaetzlein S, Kodandaramireddy NR, Ju Z, Lechel A, Stepczynska A, Lilli DR, Clark AB, Rudolph C, Kuhnel F, Wei K, Schlegelberger B, Schirmacher P, Kunkel TA, Greenberg RA, Edelmann W, Rudolph KL
    Cell 2007, 130(5), 863-77
  • LINC, a human complex that is related to pRB-containing complexes in invertebrates regulates the expression of G2/M genes.
    Schmit F, Korenjak M, Mannefeld M, Schmitt K, Franke C, von Eyss B, Gagrica S, Hänel F, Brehm A, Gaubatz S
    Cell Cycle 2007, 6(15), 1903-13
  • Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration.
    Skerka C, Lauer N, Weinberger AAWA, Keilhauer CN, Sühnel J, Smith R, Schlötzer-Schrehardt U, Fritsche L, Heinen S, Hartmann A, Weber BHF, Zipfel PF
    Mol Immunol 2007, 44(13), 3398-406
  • Composition and hierarchical organisation of a spider silk.
    Sponner A, Vater W, Monajembashi S, Unger E, Grosse F, Weisshart K
    PLoS One 2007, 2(10), e998
  • Legionella pathogenicity: genome structure, regulatory networks and the host cell response.
    Steinert M, Heuner K, Buchrieser C, Albert-Weissenberger C, Glöckner G
    Int J Med Microbiol 2007, 297(7-8), 577-87
  • Ist das Schimpansen-Genom sequenziert?
    Taudien S, Ebersberger I, Jahn N, Platzer M
    BIOspektrum 2007, 13, 386-8
  • Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis.
    Tentori L, Lacal PM, Muzi A, Dorio AS, Leonetti C, Scarsella M, Ruffini F, Xu W, Min W, Stoppacciaro A, Colarossi C, Wang ZQ, Zhang J, Graziani G
    Eur J Cancer 2007, 43(14), 2124-33
  • The short-lived fish Nothobranchius furzeri as a new model system for aging studies.
    Terzibasi E, Valenzano DR, Cellerino A
    Exp Gerontol 2007, 42(1-2), 81-9 published during change of institution
  • JunB is required for IgE-mediated degranulation and cytokine release of mast cells.
    Textor B, Licht AH, Tuckermann JP, Jessberger R, Razin E, Angel P, Schorpp-Kistner M, Hartenstein B
    J Immunol 2007, 179(10), 6873-80
  • Poly(ADP-ribose) polymerase-1 plays a role in suppressing mammary tumourigenesis in mice.
    Tong WM, Yang YgG, Cao WH, Galendo D, Frappart L, Shen Y, Wang ZQ
    Oncogene 2007, 26(26), 3857-67 published during change of institution
  • No association of sequence variants in the neuropeptide Y2 receptor (NPY2R) gene with early onset obesity in Germans.
    Wang HJ, Wermter AK, Nguyen TT, Scherag A, Reichwald K, Waldenmaier B, Lichtner P, Bettecken T, Hebebrand J, Hinney A
    Horm Metab Res 2007, 39(11), 840-4
  • PARP1 Val762Ala polymorphism reduces enzymatic activity.
    Wang XG, Wang ZQ, Tong WM, Shen Y
    Biochem Biophys Res Commun 2007, 354(1), 122-6
  • Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms.
    Wassef R, Haenold R, Hansel A, Brot N, Heinemann SH, Hoshi T
    J Neurosci 2007, 27(47), 12808-16
  • Analysis of structures causing instabilities.
    Wilhelm T
    Phys Rev E 2007, 76(1 Pt 1), 011911 published during change of institution
  • Gain and loss of polyadenylation signals during evolution of green algae.
    Wodniok S, Simon A, Glöckner G, Becker B
    BMC Evol Biol 2007, 7, 65
  • C620R mutation of the murine ret proto-oncogene: loss of function effect in homozygotes and possible gain of function effect in heterozygotes.
    Yin L, Puliti A, Bonora E, Evangelisti C, Conti V, Tong WM, Medard JJ, Lavoué MF, Forey N, Wang LC, Manié S, Morel G, Raccurt M, Wang ZQ, Romeo G
    Int J Cancer 2007, 121(2), 292-300 published during change of institution
  • Werner syndrome helicase (WRN), nuclear DNA helicase II (NDH II) and histone gammaH2AX are localized to the centrosome.
    Zhang S, Hemmerich P, Grosse F
    Cell Biol Int 2007, 31(10), 1109-21
  • Centrosomal localization of DNA damage checkpoint proteins.
    Zhang S, Hemmerich P, Grosse F
    J Cell Biochem 2007, 101(2), 451-65
  • Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H
    J Med Chem 2007, 50(24), 6059-66

Publications 2006:

  • Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.
    Abraham SM, Lawrence T, Kleiman A, Warden P, Medghalchi M, Tuckermann J, Saklatvala J, Clark AR
    J Exp Med 2006, 203(8), 1883-9
  • Finding Infeasible Reactions in Metabolic Networks: Comparison of Methods.
    Aho T, Wilhelm T, Beyer A, Schuster S, Yli-Harja O
    In: Proceedings of the 4th TICSP Workshop on Computational Systems Biology 2006, TICSP Series 2006, 32, 23-26, Tampere University of Tec
  • Ubiquitous cancer genes: multipurpose molecules for protein micro-arrays.
    Altenberg B, Gemuend C, Greulich KO
    Proteomics 2006, 6(1), 67-71
  • Ontogeny and postnatal development of the splenic vascular beds: regional cues, phenotypic responses.
    Balogh P, Balázs M, Schumacher A, Weih F, Arnold HH
    In: Embryonic Stem Cell Research (edited by Greer, Erik V), Stem Cells - Laboratory and Clinical Research 2006, 143-169, Nova Sciences Inc., Hau
  • Assembly of Nanoparticle Ring Structures Based on Protein Templates.
    Behrens S, Habicht W, Wagner K, Unger E
    Adv Mater 2006, 18(3), 284-9
  • Tubulin assemblies as biomolecular templates for nanostructure synthesis: from nanoparticle arrays to nanowires.
    Behrens S, Habicht W, Wu J, Unger E
    Surf Interface Anal 2006, 38(6), 1014-8
  • Polymyxin B-conjugated alpha 2-macroglobulin as an adjunctive therapy to sepsis: Modes of action and impact on lethality.
    Birkenmeier G, Nicklisch S, Pockelt C, Mossie A, Steger V, Gläser C, Hauschildt S, Usbeck E, Huse K, Sack U, Bauer M, Schäfer A
    J Pharmacol Exp Ther 2006, 318(2), 762-71
  • Identification and comparative expression analysis of a second wt1 gene in zebrafish.
    Bollig F, Mehringer R, Perner B, Hartung C, Schäfer M, Schartl M, Volff JN, Winkler C, Englert C
    Dev Dyn 2006, 235(2), 554-61
  • A Directed Binding Mechanism of Processive Motion for the Kinesin Motor Protein Families.
    Bolterauer H, Tuszynski JA, Unger E
    Acta Phys Pol B 2006, 37(5), 1425-43
  • Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice.
    Cozzi A, Cipriani G, Fossati S, Faraco G, Formentini L, Min W, Cortes U, Wang ZQ, Moroni F, Chiarugi A
    J Cereb Blood Flow Metab 2006, 26(5), 684-95 published during change of institution
  • Poly(ADP-ribose) glycohydrolase activity mediates post-traumatic inflammatory reaction after experimental spinal cord trauma.
    Cuzzocrea S, Genovese T, Mazzon E, Crisafulli C, Min W, Di Paola R, Muià C, Li JH, Esposito E, Bramanti P, Xu W, Massuda E, Zhang J, Wang ZQ
    J Pharmacol Exp Ther 2006, 319(1), 127-38 published during change of institution
  • Ligand-independent and EGF receptor-supported transactivation: lessons from beta2-adrenergic receptor signalling.
    Drube S, Stirnweiss J, Valkova C, Liebmann C
    Cell Signal 2006, 18(10), 1633-46
  • SNPSplicer: systematic analysis of SNP-dependent splicing in genotyped cDNAs.
    ElSharawy A, Manaster C, Teuber M, Rosenstiel P, Kwiatkowski R, Huse K, Platzer M, Becker A, Nürnberg P, Schreiber S, Hampe J
    Hum Mutat 2006, 27(11), 1129-34
  • Apomyoglobin reveals a random-nucleation mechanism in amyloid protofibril formation.
    Fändrich M, Zandomeneghi G, Krebs MRH, Kittler M, Buder K, Rossner A, Heinemann SH, Dobson CM, Diekmann S
    Acta Histochem 2006, 108(3), 215-9
  • Gene expression profiling in insulinomas of Men1 beta-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic beta-cell tumorigenesis.
    Fontanière S, Tost J, Wierinckx A, Lachuer J, Lu J, Hussein N, Busato F, Gut I, Wang ZQ, Zhang CX
    Endocr Relat Cancer 2006, 13(4), 1223-36
  • Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts.
    Fossati S, Formentini L, Wang ZQ, Moroni F, Chiarugi A
    Biochem Cell Biol 2006, 84(5), 703-12 published during change of institution
  • Paired helical filaments contain small amounts of cholesterol, phosphatidylcholine and sphingolipids.
    Gellermann GP, Appel TR, Davies P, Diekmann S
    Biol Chem 2006, 387(9), 1267-74
  • Alzheimer-like plaque formation by human macrophages is reduced by fibrillation inhibitors and lovastatin.
    Gellermann GP, Ullrich K, Tannert A, Unger C, Habicht G, Sauter SRN, Hortschansky P, Horn U, Möllmann U, Decker M, Lehmann J, Fändrich M
    J Mol Biol 2006, 360(2), 251-7
  • Lipoprotein Receptor-related Protein 1 (LRP1) - one of the Hallmarks of Alzheimer's Disease and other Complex Degenerative Processes.
    Gläser C, Birkenmeier G, Schulz S, Huse K
    In: New Research on Alzheimer's Disease 2006, 99-123, Nova Sciences Inc., Haup
  • Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity.
    Glöckner G, Schulte-Spechtel U, Schilhabel M, Felder M, Sühnel J, Wilske B, Platzer M
    BMC Genomics 2006, 7, 211
  • Inhibition of APP trafficking by tau protein does not increase the generation of amyloid-beta peptides.
    Goldsbury C, Mocanu MM, Thies E, Kaether C, Haass C, Keller P, Biernat J, Mandelkow E, Mandelkow EM
    Traffic 2006, 7(7), 873-88
  • The single DNA molecule as analytical target and as building block.
    Greulich KO
    Lab Plus Int 2006, April/May, 12 –14
  • Single DNA, RNA and protein molecules at work.
    Greulich KO
    In: Proteins, From analysis to structural genomics (edited by Meyers, Robert A) 2006, 2, 833-858, Wiley-VCH Verlagsgesell
  • Efficacy of oncolytic herpesvirus NV1020 can be enhanced by combination with chemotherapeutics in colon carcinoma cells.
    Gutermann A, Mayer E, von Dehn-Rothfelser K, Breidenstein C, Weber M, Muench M, Gungor D, Suehnel J, Moebius U, Lechmann M
    Hum Gene Ther 2006, 17(12), 1241-53
  • Cylindrical and ring-shaped tubulin assemblies as metallization templates explored by FESEM/EDX and SFM.
    Habicht W, Behrens S, Unger E, Dinjus E
    Surf Interface Anal 2006, 38(4), 194-7
  • Retinal pigment epithelium cell damage by A2-E and its photo-derivatives.
    Hammer M, Richter S, Guehrs KH, Schweitzer D
    Mol Vis 2006, 12, 1348-54
  • Near-field scanning optical microscopy in cell biology and cytogenetics.
    Hausmann M, Perner B, Rapp A, Wollweber L, Scherthan H, Greulich KO
    Methods Mol Biol 2006, 319, 275-94
  • Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain.
    Heidel F, Solem FK, Breitenbuecher F, Lipka DB, Kasper S, Thiede MH, Brandts C, Serve H, Roesel J, Giles F, Feldman E, Ehninger G, Schiller GJ, Nimer S, Stone RM, Wang Y, Kindler T, Cohen PS, Huber C, Fischer T
    Blood 2006, 107(1), 293-300
  • Single-nucleotide polymorphisms in NAGNAG acceptors are highly predictive for variations of alternative splicing.
    Hiller M, Huse K, Szafranski K, Jahn N, Hampe J, Schreiber S, Backofen R, Platzer M
    Am J Hum Genet 2006, 78(2), 291-302
  • Phylogenetically widespread alternative splicing at unusual GYNGYN donors.
    Hiller M, Huse K, Szafranski K, Rosenstiel P, Schreiber S, Backofen R, Platzer M
    Genome Biol 2006, 7(7), R65
  • Alternative splicing at NAGNAG acceptors: simply noise or noise and more?
    Hiller M, Szafranski K, Backofen R, Platzer M
    PLoS Genet 2006, 2(11), e207
  • Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany.
    Hinney A, Bettecken T, Tarnow P, Brumm H, Reichwald K, Lichtner P, Scherag A, Nguyen TT, Schlumberger P, Rief W, Vollmert C, Illig T, Wichmann HE, Schäfer H, Platzer M, Biebermann H, Meitinger T, Hebebrand J
    J Clin Endocrinol Metab 2006, 91(5), 1761-9
  • Monolaterol, the first configurationally assigned phenylphenalenone derivative with a stereogenic center at C-9, from Monochoria elata.
    Hölscher D, Reichert M, Görls H, Ohlenschläger O, Bringmann G, Schneider B
    J Nat Prod 2006, 69(11), 1614-7
  • JNK signaling coordinates integrin and actin functions during Drosophila embryogenesis.
    Homsy JG, Jasper H, Peralta XG, Wu H, Kiehart DP, Bohmann D
    Dev Dyn 2006, 235(2), 427-34
  • Migration in action: profiling border cells.
    Jasper H
    Dev Cell 2006, 10(4), 414-5
  • German human methylome project started.
    Jeltsch A, Walter J, Reinhardt R, Platzer M
    Cancer Res 2006, 66(14), 7378
  • Telomeres and telomerase in stem cells during aging and disease.
    Ju Z, Rudolph KL
    Genome Dyn 2006, 1, 84-103
  • Telomeres and telomerase in cancer stem cells.
    Ju Z, Rudolph KL
    Eur J Cancer 2006, 42(9), 1197-203
  • Assembly, trafficking and function of gamma-secretase.
    Kaether C, Haass C, Steiner H
    Neurodegener Dis 2006, 3(4-5), 275-83 published during change of institution
  • Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface.
    Kaether C, Schmitt S, Willem M, Haass C
    Traffic 2006, 7(4), 408-15
  • Topoisomerase II beta expression level correlates with doxorubicin-induced apoptosis in peripheral blood cells.
    Kersting G, Tzvetkov MV, Huse K, Kulle B, Hafner V, Brockmöller J, Wojnowski L
    Naunyn Schmiedebergs Arch Pharmacol 2006, 374(1), 21-30
  • Chemoocclusion vs chemoperfusion for treatment of advanced hepatocellular carcinoma: a randomised trial.
    Kirchhoff TD, Rudolph KL, Layer G, Chavan A, Greten TF, Rosenthal H, Kubicka S, Galanski M, Manns MP, Schild H, Gallkowski U
    Eur J Surg Oncol 2006, 32(2), 201-7
  • Self-organized pattern fonnation of biomolecules at silicon surfaces: Intended application of a dislocation network.
    Kittler M, Yu X, Vyvenko OF, Birkholz M, Seifert W, Reiche M, Wilhelm T, Arguirov T, Wolff A, Fritzsche W, Seibt M
    Mat Sci Eng C 2006, 26(5-7), 902-10 published during change of institution
  • The potential of a new stable ultrasound contrast agent for site-specific targeting. An in vitro experiment.
    Korosoglou G, Behrens S, Bekeredjian R, Hardt S, Hagenmueller M, Dinjus E, Böhm KJ, Unger E, Katus HA, Kuecherer H
    Ultrasound Med Biol 2006, 32(10), 1473-8
  • Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues.
    Lo JC, Basak S, James ES, Quiambo RS, Kinsella MC, Alegre ML, Weih F, Franzoso G, Hoffmann A, Fu YX
    Blood 2006, 107(3), 1048-55 published during change of institution
  • Epigenetic information in chromatin: the code of entry for DNA repair.
    Loizou JI, Murr R, Finkbeiner MG, Sawan C, Wang ZQ, Herceg Z
    Cell Cycle 2006, 5(7), 696-701 published during change of institution
  • Distance determination in protein-DNA complexes using fluorescence resonance energy transfer.
    Lorenz M, Diekmann S
    Methods Mol Biol 2006, 335, 243-55
  • Analysis of expressed sequence tags (ESTs) from the polar diatom Fragilariopsis cylindrus.
    Mock T, Krell A, Glöckner G, Kolukisaoglu Ü, Valentin K
    J Phycol 2006, 42(1), 78-85
  • UVA-induced apoptosis studied by the new apo/necro-Comet-assay which distinguishes viable, apoptotic and necrotic cells.
    Morley N, Rapp A, Dittmar H, Salter L, Gould D, Greulich KO, Curnow A
    Mutagenesis 2006, 21(2), 105-14
  • Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks.
    Murr R, Loizou JI, Yang YG, Cuenin C, Li H, Wang ZQ, Herceg Z
    Nat Cell Biol 2006, 8(1), 91-9 published during change of institution
  • A short PNA targeting coxsackievirus B3 5'-nontranslated region prevents virus-induced cytolysis.
    Musumeci D, Valente M, Capasso D, Palumbo R, Görlach M, Schmidtke M, Zell R, Roviello GN, Sapio R, Pedone C, Bucci EM
    J Pept Sci 2006, 12(3), 161-70
  • Isotopic labeling of recombinant proteins expressed in the protozoan host Leishmania tarentolae.
    Niculae A, Bayer P, Cirstea I, Bergbrede T, Pietrucha R, Gruen M, Breitling R, Alexandrov K
    Protein Expr Purif 2006, 48(2), 167-72
  • Novel singly labelled probes for identification of microorganisms, detection of antibiotic resistance genes and mutations, and tumor diagnosis (Smart Probes).
    Nolte O, Müller M, Häfner B, Knemeyer JP, Stöhr K, Wolfrum J, Hakenbeck R, Denapaite D, Schwarz-Finsterle J, Stein S, Schmitt E, Cremer C, Herten DP, Hausmann M
    In: Biophotonics: Visions for Better Health Care (edited by Popp J, Strehle M) 2006, 167-230, Wiley-VCH Verlagsgesell
  • DNA sequence and analysis of human chromosome 8.
    Nusbaum C, Mikkelsen TS, Zody MC, Asakawa S, Taudien S, Garber M, Kodira CD, Schueler MG, Shimizu A, Whittaker CA, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Yang X, Allen NR, Anderson S, Asakawa T, Blechschmidt K, Bloom T, Borowsky ML, Butler J, Cook A, Corum B, DeArellano K, DeCaprio D, Dooley KT, Dorris L, Engels R, Glöckner G, Hafez N, Hagopian DS, Hall JL, Ishikawa SK, Jaffe DB, Kamat A, Kudoh J, Lehmann R, Lokitsang T, Macdonald P, Major JE, Matthews CD, Mauceli E, Menzel U, Mihalev AH, Minoshima S, Murayama Y, Naylor JW, Nicol R, Nguyen C, O'Leary SB, O'Neill K, Parker SCJ, Polley A, Raymond CK, Reichwald K, Rodriguez J, Sasaki T, Schilhabel M, Siddiqui R, Smith CL, Sneddon TP, Talamas JA, Tenzin P, Topham K, Venkataraman V, Wen G, Yamazaki S, Young SK, Zeng Q, Zimmer AR, Rosenthal A, Birren BW, Platzer M, Shimizu N, Lander ES
    Nature 2006, 439(7074), 331-5
  • Design, synthesis, and biological evaluation of 3,4-diarylmaleimides as angiogenesis inhibitors.
    Peifer C, Stoiber T, Unger E, Totzke F, Schächtele C, Marmé D, Brenk R, Klebe G, Schollmeyer D, Dannhardt G
    J Med Chem 2006, 49(4), 1271-81
  • Mutagenic exploration of the cross-seeding and fibrillation propensity of Alzheimer's beta-amyloid peptide variants.
    Peim A, Hortschansky P, Christopeit T, Schroeckh V, Richter W, Fändrich M
    Protein Sci 2006, 15(7), 1801-5
  • The Human Genome and Its Upcoming Dynamics.
    Platzer M
    In: Genome Dynamics, Vertebrate Genomes (edited by Volff JN) 2006, 2, 1-16, Karger, Basel
  • Die Variabilität der Plastizität - Proteinvielfalt durch subtiles alternatives Spleißen an NAGNAG- Motiven.
    Platzer M, Hiller M, Huse K, Szafranski K, Hampe J, Backofen R, Schreiber S
    GenomXPress 2006, 1, 4-6
  • Sequencing errors or SNPs at splice-acceptor guanines in dbSNP?
    Platzer M, Hiller M, Szafranski K, Jahn N, Hampe J, Schreiber S, Backofen R, Huse K
    Nat Biotechnol 2006, 24(9), 1068-70
  • [Telomere dysfunction and telomerase: implications for human pathophysiology during ageing and chronic diseases].
    Plentz RR, Rudolph KL
    Dtsch Med Wochenschr 2006, 131(38), 2087-90
  • ALys amyloidosis caused by compound heterozygosity in exon 2 (Thr70Asn) and exon 4 (Trp112Arg) of the lysozyme gene.
    Röcken C, Becker K, Fändrich M, Schroeckh V, Stix B, Rath T, Kähne T, Dierkes J, Roessner A, Albert FW
    Hum Mutat 2006, 27(1), 119-20
  • Cathepsin protease activity modulates amyloid load in extracerebral amyloidosis.
    Röcken C, Fändrich M, Stix B, Tannert A, Hortschansky P, Reinheckel T, Saftig P, Kähne T, Menard R, Ancsin JB, Bühling F
    J Pathol 2006, 210(4), 478-87
  • X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition.
    Rohr KB, Selwood T, Marquardt U, Huber R, Schechter NM, Bode W, Than ME
    J Mol Biol 2006, 357(1), 195-209 published during change of institution
  • A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways.
    Rosenstiel P, Huse K, Till A, Hampe J, Hellmig S, Sina C, Billmann S, von Kampen O, Waetzig GH, Platzer M, Seegert D, Schreiber S
    Proc Natl Acad Sci U S A 2006, 103(9), 3280-5
  • [Antibodies to stuctural proteins of endogenous retrovirus of the HERV-K/HTDV family as markers of human germ cell tumors].
    Seniuta NB, Kleiman AM, Triakin AA, Karseladze AI, Shelepova VM, Tiuliandin SA, Gurtsevich VE
    Vopr Virusol 2006, 51(3), 17-21
  • The analysis of cell division and cell wall synthesis genes reveals mutationally inactivated ftsQ and mraY in a protoplast-type L-form of Escherichia coli.
    Siddiqui RA, Hoischen C, Holst O, Heinze I, Schlott B, Gumpert J, Diekmann S, Grosse F, Platzer M
    FEMS Microbiol Lett 2006, 258(2), 305-11
  • EST analysis of the scaly green flagellate Mesostigma viride (Streptophyta): implications for the evolution of green plants (Viridiplantae).
    Simon* A, Glöckner* G, Felder M, Melkonian M, Becker B
    BMC Plant Biol 2006, 6, 2 * equal contribution
  • Role of RNA polymerase III transcription factors in the selection of integration sites by the dictyostelium non-long terminal repeat retrotransposon TRE5-A.
    Siol O, Boutliliss M, Chung T, Glöckner G, Dingermann T, Winckler T
    Mol Cell Biol 2006, 26(22), 8242-51
  • Human topoisomerase I forms double cleavage complexes on natural DNA.
    Søe K, Hartung S, Grosse F
    Biochem Biophys Res Commun 2006, 349(1), 178-85
  • Pore-forming scissors? A first structural glimpse of gamma-secretase.
    Steiner H, Than M, Bode W, Haass C
    Trends Biochem Sci 2006, 31(9), 491-3 published during change of institution
  • Model Host Systems: Tools for Comprehensive Analysis of Host-Pathogen Interactions.
    Steinert M, Glöckner G
    In: Pathogenomics 2006, 445-456, Wiley-VCH Verlagsgesell
  • Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase.
    Steinmetzer T, Schweinitz A, Stürzebecher A, Dönnecke D, Uhland K, Schuster O, Steinmetzer P, Müller F, Friedrich R, Than ME, Bode W, Stürzebecher J
    J Med Chem 2006, 49(14), 4116-26 published during change of institution
  • The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220.
    Stumpf M, Waskow C, Krötschel M, van Essen D, Rodriguez P, Zhang X, Guyot B, Roeder RG, Borggrefe T
    Proc Natl Acad Sci U S A 2006, 103(49), 18504-9
  • tuple_plot: fast pairwise nucleotide sequence comparison with noise suppression.
    Szafranski K, Jahn N, Platzer M
    Bioinformatics 2006, 22(15), 1917-8
  • Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin.
    Tanaka Y, Igarashi S, Nakamura M, Gafni J, Torcassi C, Schilling G, Crippen D, Wood JD, Sawa A, Jenkins NA, Copeland NG, Borchelt DR, Ross CA, Ellerby LM
    Neurobiol Dis 2006, 21(2), 381-91
  • Should the draft chimpanzee sequence be finished?
    Taudien S, Ebersberger I, Glöckner G, Platzer M
    Trends Genet 2006, 22(3), 122-5
  • Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice.
    Tong WM, Lee MK, Galendo D, Wang ZQ, Sabapathy K
    Int J Cancer 2006, 119(4), 745-9 published during change of institution
  • Resveratrol and the pharmacology of aging: a new vertebrate model to validate an old molecule.
    Valenzano DR, Cellerino A
    Cell Cycle 2006, 5(10), 1027-32
  • Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate.
    Valenzano DR, Terzibasi E, Genade T, Cattaneo A, Domenici L, Cellerino A
    Curr Biol 2006, 16(3), 296-300
  • Spatiotemporal expression of connexin 39 and -43 during myoblast differentiation in cultured cells and in the mouse embryo.
    von Maltzahn J, Wulf V, Willecke K
    Cell Commun Adhes 2006, 13(1-2), 55-60
  • The TatAd component of the Bacillus subtilis twin-arginine protein transport system forms homo-multimeric complexes in its cytosolic and membrane embedded localisation.
    Westermann M, Pop OI, Gerlach R, Appel TR, Schlörmann W, Schreiber S, Müller JP
    Bba-Biomembranes 2006, 1758(4), 443-51
  • Differential receptor activation by cockroach adipokinetic hormones produces differential effects on ion currents, neuronal activity, and locomotion.
    Wicher D, Agricola HJ, Söhler S, Gundel M, Heinemann SH, Wollweber L, Stengl M, Derst C
    J Neurophysiol 2006, 95(4), 2314-25
  • Analysis of translation initiation using a translation control reporter system.
    Wiesenthal V, Leutz A, Calkhoven CF
    Nat Protoc 2006, 1(3), 1531-7
  • A translation control reporter system (TCRS) for the analysis of translationally controlled processes in the vertebrate cell.
    Wiesenthal V, Leutz A, Calkhoven CF
    Nucleic Acids Res 2006, 34(3), e23
  • Molecular biology on the ICU. From understanding to treating sepsis.
    Winning J, Claus RA, Huse K, Bauer M
    Minerva Anestesiol 2006, 72(5), 255-67
  • The GxGD motif of presenilin contributes to catalytic function and substrate identification of gamma-secretase.
    Yamasaki A, Eimer S, Okochi M, Smialowska A, Kaether C, Baumeister R, Haass C, Steiner H
    J Neurosci 2006, 26(14), 3821-8 published during change of institution
  • A novel function of DNA repair molecule Nbs1 in terminal differentiation of the lens fibre cells and cataractogenesis.
    Yang YG, Frappart PO, Frappart L, Wang ZQ, Tong WM
    DNA Repair 2006, 5(8), 885-93 published during change of institution
  • Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease.
    Zheng W, Rosenstiel P, Huse K, Sina C, Valentonyte R, Mah N, Zeitlmann L, Grosse J, Ruf N, Nürnberg P, Costello CM, Onnie C, Mathew C, Platzer M, Schreiber S, Hampe J
    Genes Immun 2006, 7(1), 11-8
  • 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H
    J Med Chem 2006, 49(26), 7816-25

Publications 2005:

  • Fragility of telomeres after bleomycin and cisplatin combined treatment measured in human leukocytes with the Comet-FISH technique.
    Arutyunyan R, Rapp A, Greulich KO, Hovhannisyan G, Haroutiunian S, Gebhart E
    Exp Oncol 2005, 27(1), 38-42
  • Nanoparticle Ring Structures based on Protein Assemblies.
    Behrens S, Habicht W, Wagner K, Unger E
    In: Assembly at the Nanoscale - Toward Functional Nanostructured Materials (edited by Materials Research Society), MRS Symposium Proceedings Series 2005, 901, 0901-Ra03-02, Cambridge Universi
  • Dynamic simulation of protein complex formation on a genomic scale.
    Beyer A, Wilhelm T
    Bioinformatics 2005, 21(8), 1610-6
  • Movement and Alignment of Microtubules in Electric Fields and Electric-Dipole-Moment Estimates.
    Böhm KJ, Mavromatos NE, Michette A, Stracke R, Unger E
    Electromagn Biol Med 2005, 24(3), 319-30
  • Directed binding: a novel physical mechanism that describes the directional motion of two-headed kinesin motor proteins.
    Bolterauer H, Tuszynski JA, Unger E
    Cell Biochem Biophys 2005, 42(2), 95-119
  • Genotoxicity of inorganic lead salts and disturbance of microtubule function.
    Bonacker D, Stoiber T, Böhm KJ, Prots I, Wang M, Unger E, Thier R, Bolt HM, Degen GH
    Environ Mol Mutagen 2005, 45(4), 346-53
  • Mapping the binding site of full length HIV-1 Nef on human Lck SH3 by NMR spectroscopy.
    Briese L, Preusser A, Willbold D
    J Biomed Sci 2005, 12(3), 451-6
  • Gamma-secretase complex assembly within the early secretory pathway.
    Capell A, Beher D, Prokop S, Steiner H, Kaether C, Shearman MS, Haass C
    J Biol Chem 2005, 280(8), 6471-8
  • Mutagenic analysis of the nucleation propensity of oxidized Alzheimer's beta-amyloid peptide.
    Christopeit T, Hortschansky P, Schroeckh V, Gührs K, Zandomeneghi G, Fändrich M
    Protein Sci 2005, 14(8), 2125-31
  • Molecular organization of selected prokaryotic S-layer proteins.
    Claus H, Akça E, Debaerdemaeker T, Evrard C, Declercq JP, Harris JR, Schlott B, König H
    Can J Microbiol 2005, 51(9), 731-43
  • Octopamine-immunoreactive neurons in the brain and subesophageal ganglion of the hawkmoth Manduca sexta.
    Dacks AM, Christensen TA, Agricola HJ, Wollweber L, Hildebrand JG
    J Comp Neurol 2005, 488(3), 255-68
  • Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma.
    Djojosubroto MW, Chin AC, Go N, Schaetzlein S, Manns MP, Gryaznov S, Harley CB, Rudolph KL
    Hepatology 2005, 42(5), 1127-36
  • The genome of the social amoeba Dictyostelium discoideum.
    Eichinger L, Pachebat JA, Glöckner G, Rajandream MA, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov BA, Rivero F, Bankier AT, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail MA, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox EC, Chisholm RL, Gibbs R, Loomis WF, Platzer M, Kay RR, Williams J, Dear PH, Noegel AA, Barrell B, Kuspa A
    Nature 2005, 435(7038), 43-57
  • Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons.
    Etter PD, Narayanan R, Navratilova Z, Patel C, Bohmann D, Jasper H, Ramaswami M
    Bmc Neurosci 2005, 6, 39
  • DictyMOLD-a Dictyostelium discoideum genome browser database.
    Felder M, Szafranski K, Lehmann R, Eichinger L, Noegel AA, Platzer M, Glöckner G
    Bioinformatics 2005, 21(5), 696-7
  • An essential function for NBS1 in the prevention of ataxia and cerebellar defects.
    Frappart PO, Tong WM, Demuth I, Radovanovic I, Herceg Z, Aguzzi A, Digweed M, Wang ZQ
    Nat Med 2005, 11(5), 538-44
  • Mutation screen of the brain derived neurotrophic factor gene (BDNF): identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder.
    Friedel S, Horro FF, Wermter AK, Geller F, Dempfle A, Reichwald K, Smidt J, Brönner G, Konrad K, Herpertz-Dahlmann B, Warnke A, Hemminger U, Linder M, Kiefl H, Goldschmidt HP, Siegfried W, Remschmidt H, Hinney A, Hebebrand J
    Am J Med Genet B 2005, 132B(1), 96-9
  • Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity.
    Friedemann J, Grosse F, Zhang S
    J Biol Chem 2005, 280(35), 31303-13
  • Gene expression of connective tissue growth factor in adult mouse.
    Friedrichsen S, Heuer H, Christ S, Cuthill D, Bauer K, Raivich G
    Growth Factors 2005, 23(1), 43-53 published during change of institution
  • Dual function of membrane-bound heat shock protein 70 (Hsp70), Bag-4, and Hsp40: protection against radiation-induced effects and target structure for natural killer cells.
    Gehrmann M, Marienhagen J, Eichholtz-Wirth H, Fritz E, Ellwart J, Jäättelä M, Zilch T, Multhoff G
    Cell Death Differ 2005, 12(1), 38-51 published during change of institution
  • Annual fishes of the genus Nothobranchius as a model system for aging research.
    Genade T, Benedetti M, Terzibasi E, Roncaglia P, Valenzano DR, Cattaneo A, Cellerino A
    Aging Cell 2005, 4(5), 223-33
  • N-acetyl-D-galactosamine/N-acetyl-D-glucosamine--recognizing lectin from the snail Cepaea hortensis: purification, chemical characterization, cloning and expression in E. coli.
    Gerlach D, Schlott B, Zähringer U, Schmidt KH
    FEMS Immunol Med Microbiol 2005, 43(2), 223-32
  • Gemeinsam sind wir stark - was fügt Einzelzellen zu einem Ganzen?
    Glöckner G
    GenomXPress 2005, 3, 14-5
  • Telomere structural dynamics in genome integrity control and carcinogenesis.
    Greenberg RA, Rudolph KL
    Adv Exp Med Biol 2005, 570, 311-41
  • Single-molecule studies on DNA and RNA.
    Greulich KO
    Chemphyschem 2005, 6(12), 2458-24571
  • Nucleic Acid and Protein Single Molecule Detection and Characterization.
    Greulich KO
    In: Encyclopedia of Molecular Cell Biology and Molecular Medicine 2005, 9, 269-293, Wiley-VCH Verlagsgesell
  • Oxidative damage, aging and anti-aging strategies.
    Haenold R, Wassef DM, Heinemann SH, Hoshi T
    Age (Dordr) 2005, 27(3), 183-99
  • New Technologies Measure Genome Domains - High resolution microscopy and novel labeling procedures enable 3-D studies of the functional architecture of gene domains in cell nuclei.
    Hausmann M, Hildenbrand G, Schwarz-Finsterle J, Birk U, Schneider H, Cremer C, Schmitt E
    Biophotonics Int 2005, 12, 34-7
  • Visions of the Cell Nucleus.
    Hemmerich P, Diekmann S (eds)
    2005, American Scientific Publishers,
  • Human Latrophilin-2 is Expressed in the Cytotrophoblast and Syncytiotrophoblast of Placenta and in Endothelial Cells.
    Herberth G, Stein A, Taudien S, Klaman I, Herr A, Glienke J, Thierauch KH, Sommer A
    Am J Biochem and Biotech 2005, 1(3), 136-45
  • The monocarboxylate transporter 8 linked to human psychomotor retardation is highly expressed in thyroid hormone-sensitive neuron populations.
    Heuer H, Maier MK, Iden S, Mittag J, Friesema ECH, Visser TJ, Bauer K
    Endocrinology 2005, 146(4), 1701-6 published as IMB
  • Nano-sizing of specific gene domains in intact human cell nuclei by spatially modulated illumination light microscopy.
    Hildenbrand G, Rapp A, Spöri U, Wagner C, Cremer C, Hausmann M
    Biophys J 2005, 88(6), 4312-8
  • Assessment of DNA damage in target tumor cells after thermoablation in mice.
    Hilger I, Rapp A, Greulich KO, Kaiser WA
    Radiology 2005, 237(2), 500-6
  • Non-EST based prediction of exon skipping and intron retention events using Pfam information.
    Hiller M, Huse K, Platzer M, Backofen R
    Nucleic Acids Res 2005, 33(17), 5611-21
  • Creation and disruption of protein features by alternative splicing -- a novel mechanism to modulate function.
    Hiller M, Huse K, Platzer M, Backofen R
    Genome Biol 2005, 6(7), R58 published as IMB
  • Thermodynamic analysis of the aggregation propensity of oxidized Alzheimer's beta-amyloid variants.
    Hortschansky P, Christopeit T, Schroeckh V, Fändrich M
    Protein Sci 2005, 14(11), 2915-8 published as IMB
  • The aggregation kinetics of Alzheimer's beta-amyloid peptide is controlled by stochastic nucleation.
    Hortschansky P, Schroeckh V, Christopeit T, Zandomeneghi G, Fändrich M
    Protein Sci 2005, 14(7), 1753-9
  • Comet-assay in combination with PNA-FISH detects mutagen-induced DNA damage and specific repeat sequences in the damaged DNA of transformed cells.
    Hovhannisyan G, Rapp A, Arutyunyan R, Greulich KO, Gebhart E
    Int J Mol Med 2005, 15(3), 437-42
  • DREF is required for efficient growth and cell cycle progression in Drosophila imaginal discs.
    Hyun J, Jasper H, Bohmann D
    Mol Cell Biol 2005, 25(13), 5590-8
  • Domain reorientation and induced fit upon RNA binding: solution structure and dynamics of ribosomal protein L11 from Thermotoga maritima.
    Ilin S, Hoskins A, Ohlenschläger O, Jonker HRA, Schwalbe H, Wöhnert J
    Chembiochem 2005, 6(9), 1611-8
  • Design and biological evaluation of linear and cyclic phosphopeptide ligands of the N-terminal SH2 domain of protein tyrosine phosphatase SHP-1.
    Imhof D, Wieligmann K, Hampel K, Nothmann D, Zoda MS, Schmidt-Arras D, Zacharias M, Böhmer FD, Reissmann S
    J Med Chem 2005, 48(5), 1528-39
  • A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein {beta} and NF-{kappa}B activity in Hodgkin and anaplastic large cell lymphomas.
    Jundt F, Raetzel N, Müller C, Calkhoven CF, Kley K, Mathas S, Lietz A, Leutz A, Dörken B
    Blood 2005, 106(5), 1801-7 published during change of institution
  • Breakpoint analysis of the pericentric inversion distinguishing human chromosome 4 from the homologous chromosome in the chimpanzee (Pan troglodytes).
    Kehrer-Sawatzki H, Sandig C, Chuzhanova N, Goidts V, Szamalek JM, Tänzer S, Müller S, Platzer M, Cooper DN, Hameister H
    Hum Mutat 2005, 25(1), 45-55 published as IMB
  • Molecular characterization of the pericentric inversion of chimpanzee chromosome 11 homologous to human chromosome 9.
    Kehrer-Sawatzki H, Szamalek JM, Tänzer S, Platzer M, Hameister H
    Genomics 2005, 85(5), 542-50
  • The BTB-kelch protein KLHL6 is involved in B-lymphocyte antigen receptor signaling and germinal center formation.
    Kroll J, Shi X, Caprioli A, Liu HH, Waskow C, Lin KM, Miyazaki T, Rodewald HR, Sato TN
    Mol Cell Biol 2005, 25(19), 8531-40
  • The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo.
    Lechel A, Satyanarayana A, Ju Z, Plentz RR, Schaetzlein S, Rudolph C, Wilkens L, Wiemann SU, Saretzki G, Malek NP, Manns MP, Buer J, Rudolph KL
    EMBO Rep 2005, 6(3), 275-81
  • Investigation of protein-tyrosine phosphatases by in-gel assays.
    Markova B, Gulati P, Herrlich PA, Böhmer FD
    Methods 2005, 35(1), 22-7 published during change of institution, published as IMB
  • A five-amino-acid peptide blocks Met- and Ron-dependent cell migration.
    Matzke A, Herrlich P, Ponta H, Orian-Rousseau V
    Cancer Res 2005, 65(14), 6105-10 published during change of institution, published as IMB
  • Interaction of sodium and potassium ions with sandwiched cytosine-, guanine-, thymine-, and uracil-base tetrads.
    Meyer M, Hocquet A, Sühnel J
    J Comput Chem 2005, 26(4), 352-64
  • Actinomycin D induces histone gamma-H2AX foci and complex formation of gamma-H2AX with Ku70 and nuclear DNA helicase II.
    Mischo HE, Hemmerich P, Grosse F, Zhang S
    J Biol Chem 2005, 280(10), 9586-94 published as IMB
  • Athyroid Pax8-/- mice cannot be rescued by the inactivation of thyroid hormone receptor alpha1.
    Mittag J, Friedrichsen S, Heuer H, Polsfuss S, Visser TJ, Bauer K
    Endocrinology 2005, 146(7), 3179-84 published as IMB
  • [Matrix metalloproteinases and their inhibitors in lung cancer with malignant pleural effusion].
    Moche M, Hui DSC, Huse K, Chan KS, Choy DKL, Scholz GH, Gosse H, Winkler J, Schauer J, Sack U, Hoheisel G
    Pneumologie 2005, 59(8), 523-8
  • Licht als Werkzeug in der Zell - und Molekularbiologie: Anwendungen in der Herzforschung.
    Monajembashi S, Perner B, Greulich KO
    Bioforum 2005, 9, 40-1
  • Spatial association of homologous pericentric regions in human lymphocyte nuclei during repair.
    Monajembashi S, Rapp A, Schmitt E, Dittmar H, Greulich KO, Hausmann M
    Biophys J 2005, 88(3), 2309-22
  • Genes upregulated in a metastasizing human colon carcinoma cell line.
    Orian-Rousseau V, Mink S, Mengwasser J, HogenEsch H, Guo F, Thies WG, Hofmann M, Herrlich P, Ponta H
    Int J Cancer 2005, 113(5), 699-705 published during change of institution, published as IMB
  • Expressional and functional studies of Wolframin, the gene function deficient in Wolfram syndrome, in mice and patient cells.
    Philbrook C, Fritz E, Weiher H
    Exp Gerontol 2005, 40(8-9), 671-8
  • Exploring the chemistry of uncultivated bacterial symbionts: antitumor polyketides of the pederin family.
    Piel J, Butzke D, Fusetani N, Hui D, Platzer M, Wen G, Matsunaga S
    J Nat Prod 2005, 68(3), 472-9
  • Alternatives Spleißen an NAGNAG-Motiven: kleine Ursache - große Protein-Vielfalt.
    Platzer M, Huse K, Hiller M
    Biol Unserer Zeit 2005, 35, 80-2
  • Prospective analysis of German patients with hepatocellular carcinoma undergoing transcatheter arterial chemoembolization with or without prophylactic antibiotic therapy.
    Plentz RR, Lankisch TO, Bastürk M, Müller CCM, Kirchhoff T, Gebel M, Bleck JS, Kubicka S, Manns MP, Meier PN, Rudolph KL
    J Gastroenterol Hepatol 2005, 20(7), 1134-6
  • Telomere shortening correlates with increasing aneuploidy of chromosome 8 in human hepatocellular carcinoma.
    Plentz RR, Schlegelberger B, Flemming P, Gebel M, Kreipe H, Manns MP, Rudolph KL, Wilkens L
    Hepatology 2005, 42(3), 522-6
  • Hepatocellular carcinoma and octreotide: treatment results in prospectively assigned patients with advanced tumor and cirrhosis stage.
    Plentz RR, Tillmann HL, Kubicka S, Bleck JS, Gebel M, Manns MP, Rudolph KL
    J Gastroenterol Hepatol 2005, 20(9), 1422-8
  • Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3' to 5' DNA helicase.
    Prakash R, Krejci L, Van Komen S, Schürer KA, Kramer W, Sung P
    J Biol Chem 2005, 280(9), 7854-60 research results from former institution
  • Listeria monocytogenes exploits ERM protein functions to efficiently spread from cell to cell.
    Pust* S, Morrison* H, Wehland J, Sechi AS, Herrlich P
    EMBO J 2005, 24(6), 1287-300 * equal contribution, published during change of institution
  • A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor.
    Ramser J, Abidi FE, Burckle CA, Lenski C, Toriello H, Wen G, Lubs HA, Engert S, Stevenson RE, Meindl A, Schwartz CE, Nguyen G
    Hum Mol Genet 2005, 14(8), 1019-27 published as IMB
  • Structural studies on LNA quadruplexes.
    Randazzo A, Esposito V, Ohlenschläger O, Ramachandran R, Virgilio A, Mayol L
    Nucleosides Nucleotides Nucleic Acids 2005, 24(5-7), 795-800
  • Damage in Human Cell Nuclei in Toxicology, Nutrition and Cancer: Visualization by Comet Assay and Comet-FISH.
    Rapp A, Greulich KO, Schäferhenrich A, Louise Pool-Zobel B
    In: Visions of the Cell Nucleus (edited by Hemmerich P, Diekmann S) 2005, 281-304, American Scientific Pub
  • The comet-FISH technique: a tool for detection of specific DNA damage and repair.
    Rapp A, Hausmann M, Greulich KO
    Methods Mol Biol 2005, 291, 107-19
  • Characterisation of hydrogen bonding networks in RNAs via magic angle spinning solid state NMR spectroscopy.
    Riedel K, Leppert J, Ohlenschläger O, Görlach M, Ramachandran R
    J Biomol NMR 2005, 31(4), 331-6
  • Refinement of protein cores and protein-peptide interfaces using a potential scaling approach.
    Riemann RN, Zacharias M
    Protein Eng Des Sel 2005, 18(10), 465-76
  • A novel transgenic mouse model reveals humanlike regulation of an 8-kbp human TERT gene promoter fragment in normal and tumor tissues.
    Ritz JM, Kühle O, Riethdorf S, Sipos B, Deppert W, Englert C, Günes C
    Cancer Res 2005, 65(4), 1187-96 published as IMB
  • GenColors: accelerated comparative analysis and annotation of prokaryotic genomes at various stages of completeness.
    Romualdi A, Siddiqui R, Glöckner G, Lehmann R, Sühnel J
    Bioinformatics 2005, 21(18), 3669-71
  • The DNA sequence of the human X chromosome.
    Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RIS, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Glöckner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl P, Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, Müller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell CN, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J, Bentley DR
    Nature 2005, 434(7031), 325-37
  • Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes.
    Rubio-Moscardo F, Blesa D, Mestre C, Siebert R, Balasas T, Benito A, Rosenwald A, Climent J, Martinez JI, Schilhabel M, Karran EL, Gesk S, Esteller M, deLeeuw R, Staudt LM, Fernandez-Luna JL, Pinkel D, Dyer MJS, Martinez-Climent JA
    Blood 2005, 106(9), 3214-22
  • Telomeres and telomerase influence the course of human diseases, aging and carcinogenesis.
    Rudolph KL
    Curr Mol Med 2005, 5(2), 133-4
  • Hepatitis C virus infection in the elderly
    Rudolph LK, Tillmann HL
    Aging Health 2005, 1(3), 409-17
  • Telomeres and Telomerase: Distinctive Roles in Liver Regeneration, Cirrhosis and Carcinogenesis
    Satyanarayana A, Rudolph KL
    In: Signaling Pathways in Liver Diseases (edited by Jean-François D, Pierre-Alain C, Christian T, Rolf G) 2005, 333-339, Springer, Heidelberg
  • Telomere length regulation during cloning, embryogenesis and ageing.
    Schaetzlein S, Rudolph KL
    Reprod Fertil Dev 2005, 17(1-2), 85-96
  • Human galanin (GAL) and galanin 1 receptor (GALR1) variations are not involved in fat intake and early onset obesity.
    Schäuble N, Reichwald K, Grassl W, Bechstein H, Müller HC, Scherag A, Geller F, Utting M, Siegfried W, Goldschmidt H, Blundell J, Lawton C, Alam R, Whybrow S, Stubbs J, Platzer M, Hebebrand J, Hinney A
    J Nutr 2005, 135(6), 1387-92
  • COMBO-FISH for focussed fluorescence labelling of gene domains: 3D-analysis of the genome architecture of abl and bcr in human blood cells.
    Schwarz-Finsterle J, Stein S, Grossmann C, Schmitt E, Schneider H, Trakhtenbrot L, Rechavi G, Amariglio N, Cremer C, Hausmann M
    Cell Biol Int 2005, 29(12), 1038-46 published as IMB
  • A novel multidomain transcription coactivator SAYP can also repress transcription in heterochromatin.
    Shidlovskii YV, Krasnov AN, Nikolenko JV, Lebedeva LA, Kopantseva M, Ermolaeva MA, Ilyin YV, Nabirochkina EN, Georgiev PG, Georgieva SG
    EMBO J 2005, 24(1), 97-107
  • Characterization of the protein components of Nephila clavipes dragline silk.
    Sponner A, Schlott B, Vollrath F, Unger E, Grosse F, Weisshart K
    Biochemistry 2005, 44(12), 4727-36 published as IMB
  • Differential polymerization of the two main protein components of dragline silk during fibre spinning.
    Sponner A, Unger E, Grosse F, Weisshart K
    Nat Mater 2005, 4(10), 772-5
  • The conserved C-termini contribute to the properties of spider silk fibroins.
    Sponner A, Vater W, Rommerskirch W, Vollrath F, Unger E, Grosse F, Weisshart K
    Biochem Biophys Res Commun 2005, 338(2), 897-902
  • Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of keratoepithelin.
    Stix B, Leber M, Bingemer P, Gross C, Rüschoff J, Fändrich M, Schorderet DF, Vorwerk CK, Zacharias M, Roessner A, Röcken C
    Invest Ophthalmol Vis Sci 2005, 46(4), 1133-9
  • Stable chromosomal association of MSL2 defines a dosage-compensated nuclear compartment.
    Straub T, Neumann MF, Prestel M, Kremmer E, Kaether C, Haass C, Becker PB
    Chromosoma 2005, 114(5), 352-64 published during change of institution
  • Gene organization features in A/T-rich organisms.
    Szafranski K, Lehmann R, Parra G, Guigo R, Glöckner G
    J Mol Evol 2005, 60(1), 90-8
  • Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit (CFU-E).
    Terszowski G, Waskow C, Conradt P, Lenze D, Koenigsmann J, Carstanjen D, Horak I, Rodewald HR
    Blood 2005, 105(5), 1937-45
  • The endoproteinase furin contains two essential Ca2+ ions stabilizing its N-terminus and the unique S1 specificity pocket.
    Than ME, Henrich S, Bourenkov GP, Bartunik HD, Huber R, Bode W
    Acta Crystallogr D Biol Crystallogr 2005, 61(Pt 5), 505-12
  • Merging models of hepatitis C virus pathogenesis.
    Tillmann HL, Manns MP, Rudolph KL
    Semin Liver Dis 2005, 25(1), 84-92
  • Insights into human Lck SH3 domain binding specificity: different binding modes of artificial and native ligands.
    Tran T, Hoffmann S, Wiesehan K, Jonas E, Luge C, Aladag A, Willbold D
    Biochemistry 2005, 44(45), 15042-52
  • Molecular mechanisms of glucocorticoids in the control of inflammation and lymphocyte apoptosis.
    Tuckermann JP, Kleiman A, McPherson KG, Reichardt HM
    Crit Rev Clin Lab Sci 2005, 42(1), 71-104
  • Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model.
    Uhlirova M, Jasper H, Bohmann D
    Proc Natl Acad Sci U S A 2005, 102(37), 13123-8
  • Microtubules in electric fields.
    Unger E, Stracke R, Michette A, Mavromatos N, Tuszynski JA, Böhm KJ
    In: Proceedings of Coherence and Electric Fields in Biological Systems, CEFBIOS July 1-4, 2005 (edited by Pokorný J), Fröhlich Centenary International Symposium 2005, 23-25, Neoset, Praha
  • Sarcoidosis is associated with a truncating splice site mutation in BTNL2.
    Valentonyte R, Hampe J, Huse K, Rosenstiel P, Albrecht M, Stenzel A, Nagy M, Gaede KI, Franke A, Haesler R, Koch A, Lengauer T, Seegert D, Reiling N, Ehlers S, Schwinger E, Platzer M, Krawczak M, Müller-Quernheim J, Schürmann M, Schreiber S
    Nat Genet 2005, 37(4), 357-64
  • Marker free detection on microarrays.
    Vaupel M, Eing A, Greulich KO, Rögener J, Schellenberg P, Martin Striebel H, Arlinghaus HF
    In: Microarray technology and its applications (edited by Müller UR, Nicolau DV) 2005, 181-207, Springer, Heidelberg
  • Molecular basis of the interaction specificity between the human glucocorticoid receptor and its endogenous steroid ligand cortisol.
    von Langen J, Fritzemeier KH, Diekmann S, Hillisch A
    Chembiochem 2005, 6(6), 1110-8
  • Subnuclear pathology.
    von Mikecz A, Hemmerich P
    In: Visions of the Cell Nucleus 2005, 184-203, American Scientific Pub
  • Structure and Function of the Nucleus: Subnuclear Pathology of Disease
    von Mikecz A, Hemmerich P
    In: Visions of the Cell Nucleus (edited by Hemmerich P, Diekmann S) 2005, 184-203, American Scientific Pub
  • Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1.
    Wagner N, Wagner KD, Theres H, Englert C, Schedl A, Scholz H
    Genes Dev 2005, 19(21), 2631-42 published as IMB
  • JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling.
    Wang MC, Bohmann D, Jasper H
    Cell 2005, 121(1), 115-25
  • Validation of mRNA/EST-based gene predictions in human Xp11.4 revealed differences to the organization of the orthologous mouse locus.
    Wen G, Ramser J, Taudien S, Gausmann U, Blechschmidt K, Frankish A, Ashurst J, Meindl A, Platzer M
    Mamm Genome 2005, 16(12), 934-41 published as IMB
  • Mutation analysis of the MCHR1 gene in human obesity.
    Wermter AK, Reichwald K, Büch T, Geller F, Platzer C, Huse K, Hess C, Remschmidt H, Gudermann T, Preibisch G, Siegfried W, Goldschmidt HP, Li WD, Price RA, Biebermann H, Krude H, Vollmert C, Wichmann HE, Illig T, Sørensen TIA, Astrup A, Larsen LH, Pedersen O, Eberlé D, Clément K, Blundell J, Wabitsch M, Schäfer H, Platzer M, Hinney A, Hebebrand J
    Eur J Endocrinol 2005, 152(6), 851-62
  • Early growth response proteins EGR-4 and EGR-3 interact with immune inflammatory mediators NF-kappaB p50 and p65.
    Wieland GD, Nehmann N, Müller D, Eibel H, Siebenlist U, Sühnel J, Zipfel PF, Skerka C
    J Cell Sci 2005, 118(Pt 14), 3203-12
  • Contrasting effects of telomere shortening on organ homeostasis, tumor suppression, and survival during chronic liver damage.
    Wiemann SU, Satyanarayana A, Buer J, Kamino K, Manns MP, Rudolph KL
    Oncogene 2005, 24(9), 1501-9
  • A study of equal node models for food webs.
    Wilhelm T
    Ecol Modell 2005, 181(2-3), 215-27 published as IMB
  • The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles.
    Wilkins* A, Szafranski* K, Fraser DJ, Bakthavatsalam D, Müller R, Fisher PR, Glöckner G, Eichinger L, Noegel AA, Insall RH
    Genome Biol 2005, 6(8), R68 * equal contribution
  • Transfer RNA gene-targeted integration: an adaptation of retrotransposable elements to survive in the compact Dictyostelium discoideum genome.
    Winckler T, Szafranski K, Glöckner G
    Cytogenet Genome Res 2005, 110(1-4), 288-98
  • Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1.
    Wirth T, Kühnel F, Fleischmann-Mundt B, Woller N, Djojosubroto M, Rudolph KL, Manns M, Zender L, Kubicka S
    Cancer Res 2005, 65(16), 7393-402
  • Neuronal activation of NF-kappaB contributes to cell death in cerebral ischemia.
    Zhang W, Potrovita I, Tarabin V, Herrmann O, Beer V, Weih F, Schneider A, Schwaninger M
    J Cereb Blood Flow Metab 2005, 25(1), 30-40 published during change of institution

Publications 2004:

  • Spontaneous homologous recombination is decreased in Rad51C-deficient hamster cells.
    Drexler GA, Rogge S, Beisker W, Eckardt-Schupp F, Zdzienicka MZ, Fritz E
    DNA Repair 2004, 3(10), 1335-43 published as IMB
  • The rate of extrachromosomal homologous recombination within a novel reporter plasmid is elevated in cells lacking functional ATM protein.
    Drexler GA, Wilde S, Beisker W, Ellwart J, Eckardt-Schupp F, Fritz E
    DNA Repair 2004, 3(10), 1345-53 published during change of institution, published as IMB
  • Hyaluronan-oligosaccharide-induced transcription of metalloproteases.
    Fieber C, Baumann P, Vallon R, Termeer C, Simon JC, Hofmann M, Angel P, Herrlich P, Sleeman JP
    J Cell Sci 2004, 117(Pt 2), 359-67 published during change of institution
  • UVA inactivates protein tyrosine phosphatases by calpain-mediated degradation.
    Gulati P, Markova B, Göttlicher M, Böhmer FD, Herrlich PA
    EMBO Rep 2004, 5(8), 812-7 published during change of institution, published as IMB
  • Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity.
    Hiller* M, Huse* K, Szafranski K, Jahn N, Hampe J, Schreiber S, Backofen R, Platzer M
    Nat Genet 2004, 36(12), 1255-7 * equal contribution
  • Autosomal dominant congenital nystagmus is not linked to 6p12, 7p11, and 15q11 in a German family.
    Hoffmann S, Becker A, Hoerle S, Metz A, Oertel WH, Sommer N, Hemmer B
    Am J Ophthalmol 2004, 138(3), 439-43
  • A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kappaB-regulated promoters.
    Kassel O, Schneider S, Heilbock C, Litfin M, Göttlicher M, Herrlich P
    Genes Dev 2004, 18(20), 2518-28 published during change of institution, published as IMB
  • The role of the polio virus receptor and the herpesvirus entry mediator B genes for the development of MS.
    Rosche B, Cepok S, Stei S, Vogel F, Grummel V, Hoffmann S, Kroner A, Mäurer M, Rieckmann P, Sommer N, Hemmer B
    J Neuroimmunol 2004, 156(1-2), 171-7
  • Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice.
    Schilling G, Savonenko AV, Coonfield ML, Morton JL, Vorovich E, Gale A, Neslon C, Chan N, Eaton M, Fromholt D, Ross CA, Borchelt DR
    Exp Neurol 2004, 187(1), 137-49
  • Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice.
    Schilling G, Savonenko AV, Klevytska A, Morton JL, Tucker SM, Poirier M, Gale A, Chan N, Gonzales V, Slunt HH, Coonfield ML, Jenkins NA, Copeland NG, Ross CA, Borchelt DR
    Hum Mol Genet 2004, 13(15), 1599-610
  • Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair.
    Schürer KA, Rudolph C, Ulrich HD, Kramer W
    Genetics 2004, 166(4), 1673-86 to be checked
  • Towards dissecting the complexity of the AP-1 (activator protein 1) family.
    Unal R, Weih F, Schorle H, Herrlich P
    Adv Exp Med Biol 2004, 553, 331-6 published during change of institution

Publications 2002:

  • ORFer--retrieval of protein sequences and open reading frames from GenBank and storage into relational databases or text files.
    Büssow K, Hoffmann S, Sievert V
    BMC Bioinformatics 2002, 3, 40
  • Genetische Aspekte der Multiplen Sklerose
    Hoffmann S, Hemmer B
    Der Neurologe und Psychiater 2002, 17-20
  • A novel mutation in PTPRC interferes with splicing and alters the structure of the human CD45 molecule.
    Jacobsen M, Hoffmann S, Cepok S, Stei S, Ziegler A, Sommer N, Hemmer B
    Immunogenetics 2002, 54(3), 158-63
  • Signal-dependent regulation of splicing via phosphorylation of Sam68.
    Matter N, Herrlich P, König H
    Nature 2002, 420(6916), 691-5
  • CD44 is required for two consecutive steps in HGF/c-Met signaling.
    Orian-Rousseau V, Chen L, Sleeman JP, Herrlich P, Ponta H
    Genes Dev 2002, 16(23), 3074-86

Publications 2001:

  • Viral transport and the cytoskeleton.
    Ploubidou A, Way M
    Curr Opin Cell Biol 2001, 13(1), 97-105
  • Kinesin-dependent movement on microtubules precedes actin-based motility of vaccinia virus.
    Rietdorf J, Ploubidou A, Reckmann I, Holmström A, Frischknecht F, Zettl M, Zimmermann T, Way M
    Nat Cell Biol 2001, 3(11), 992-1000

Publications 2000:

  • Vaccinia virus infection disrupts microtubule organization and centrosome function.
    Ploubidou A, Moreau V, Ashman K, Reckmann I, González C, Way M
    EMBO J 2000, 19(15), 3932-44

Publications 1990:

  • Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone.
    Jonat C, Rahmsdorf HJ, Park KK, Cato AC, Gebel S, Ponta H, Herrlich P
    Cell 1990, 62(6), 1189-204