Yulin Chen

China
Phone: +49 3641 656844
Email: yulin.chen@leibniz-fli.de

Functional genomics analysis of clonal mutation in aging hematopoietic stem cells and myeloid leukemia formation

Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Rudolph Research Group

First Supervisor:

Karl Lenhard Rudolph (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Publications 2019:

  • Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.
    Chen Z, Amro EM, Becker F, Hölzer M, Rasa SMM, Njeru SN, Han B, Di Sanzo S, Chen Y, Tang D, Tao S, Haenold R, Groth M, Romanov VS, Kirkpatrick JM, Kraus JM, Kestler HA, Marz M, Ori A, Neri F, Morita Y, Rudolph KL
    J Exp Med 2019, 216(1), 152-75

Scientific CV

Publications:        Gadd45a Regulates Hematopoietic Stem Cell Stress Responses in Mice.
Chen Y, Ma X, Zhang M, Wang X, Wang C, Wang H, Guo P, Yuan W, Rudolph KL, Zhan Q, Ju Z
Blood 2014, 123(6):851‐62
        Gadd45a Deletion Aggravates Hematopoietic Stem Cell Dysfunction in ATM‐deficient Mice
Chen Y, Yang R, Peng Guo, Ju Z
Protein Cell 2014, 5(1):80‐9
        Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells
Chen Y, Li D, Wang D, Liu X, Yin N, Song Y, Lu SH, Ju Z, Zhan Q
J Cell Biochem 2012, 113(12): 3643‐52
        Hematopoietic Stem Cell Aging and Cancer
Chen Y and Ju Z
In: Adult Stem Cells in Aging, Diseases and Cancer (edited by Rudolph KL), Else Kröner-Fresenius Symposia 2012, 3, 27–35, Karger Verlag, Basel