Oleksandr Dakhovnik
Ukraine
Email: oleksandr.dakhovnik@leibniz-fli.de
Metformin supplementation starting from old age C. elegans exhibits high toxicity and median lifespan reduction
Friedrich Schiller University Jena (FSU): Faculty of Biological Sciences
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Ermolaeva Research Group
First Supervisor:
Maria Ermolaeva (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))Co – Supervisor(s):
Zhao-Qi Wang (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))Publications 2019:
- Late life metformin treatment limits cell survival and shortens lifespan by triggering an aging-associated failure of energy metabolism
Espada* L, Dakhovnik* A, Chaudhari* P, Martirosyan A, Miek L, Poliezhaieva T, Schaub Y, Nair A, Döring N, Rahnis N, Werz O, Koeberle A, Kirkpatrick J, Ori A, Ermolaeva MA
bioRxiv 2019, https://doi.org/10.1101/863357 * equal contribution - Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging.
Heinze* I, Bens* M, Calzia* E, Holtze S, Dakhovnik O, Sahm A, Kirkpatrick JM, Szafranski K, Romanov N, Sama SN, Holzer K, Singer S, Ermolaeva M, Platzer** M, Hildebrandt** T, Ori** A
BMC Biol 2018, 16(1), 82 * equal contribution, ** co-senior authors - DNA-Damage-Induced Hormetic Responses
Mägdefrau AS, Ludwig K, Weigel C, Köse N, Guerra GM, Dakhovnik A, Kosan C
In: The Science of Hormesis in Health and Longevity, Chapter 13 (edited by Suresh ISR, Marios K) 2018, 149-159, Academic Press, London
