Mohamad Amr Zaini

Syrian Arab Republic
LGSA Member

Regulation of cell metabolism through post-translational modification of the C/EBPalpha transcription factor

University of Groningen and University Medical Center Groningen
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Calkhoven Research Group, University of Groningen - European Institute for the Biology of Ageing (ERIBA)

First Supervisor:

Cornelis Ferdinand Calkhoven (University of Groningen and University Medical Center Groningen)

Doctoral Disputation:

2017

Publications 2018:

  • A p300 and SIRT1 Regulated Acetylation Switch of C/EBPα Controls Mitochondrial Function.
    Zaini MA, Müller C, de Jong TV, Ackermann T, Hartleben G, Kortman G, Gührs KH, Fusetti F, Krämer OH, Guryev V, Calkhoven CF
    Cell Rep 2018, 22(2), 497-511
  • Publications 2017:

    • A screening strategy for the discovery of drugs that reduce C/EBPβ-LIP translation with potential calorie restriction mimetic properties.
      Zaini MA, Müller C, Ackermann T, Reinshagen J, Kortman G, Pless O, Calkhoven CF
      Sci Rep 2017, 7, 42603

    Publications 2016:

    • Shwachman-Bodian-Diamond syndrome (SBDS) protein deficiency impairs translation re-initiation from C/EBPα and C/EBPβ mRNAs.
      In K, Zaini MA, Müller C, Warren AJ, von Lindern M, Calkhoven CF
      Nucleic Acids Res 2016, 44(9), 4134-46