Jiesi Chen

LGSA Member

Therapeutic potential of thyroid hormone analogs in treating Allan-Herndon-Dudley Syndrome

Friedrich Schiller University Jena (FSU) - Faculty of Biology and Pharmacy
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Heuer Research Group, Leibniz Research Institute for Environmental Medicine (IUF): Heuer Research Group

First Supervisor:

Heike Heuer (Leibniz Research Institute for Environmental Medicine (IUF))

Co – Supervisor(s):

Christoph Kaether (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Doctoral Disputation:


Publications 2014:

  • In Vitro and Mouse Studies Supporting Therapeutic Utility of Triiodothyroacetic Acid in MCT8 Deficiency.
    Kersseboom* S, Horn* S, Visser WE, Chen J, Friesema ECH, Vaurs-Barrière C, Peeters RP, Heuer* H, Visser* TJ
    Mol Endocrinol 2014, 28(12), 1961-70 * equal contribution

Scientific CV

Publications from undergraduate studies:
A synthetic steroid 5α-Androst-3β,5,6-Triol blocks hypoxia/reoxygenation - Induced neuronal injuries via protection of mitochondrial function
Jiesi Chen, Tiandong Leng , Wenli Chen, Min Yan, Wei Yin, Yijun Huang, Suizhen Lin, Dayue Duan, Jun Lin, Gongxiong Wu, Jingxia Zhang and Guangmei Yan
Steroids 2013, 78(10): 996-1002
MiR-135a functions as a selective killer of malignant glioma.
S Wu, Y Lin, D Xu, J Chen, M Shu, Y Zhou, W Zhu, X Su, P Qiu and G Yan
Oncogene 2012, 34:3866-74
Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques .
Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li Y, van Gool AJ, Du H, Chen J, Chen R, Zhang P, Huang Z, Thompson JR, Meng Y, Bai Y, Wang J, Zhuo M, Wang T, Huang Y, Wei L, Li J, Wang Z, Hu H, Yang P, Le L, Stenson PD, Li B, Liu X, Ball EV, An N, Huang Q, Zhang Y, Fan W, Zhang X, Li Y, Wang W, Katze MG, Su B, Nielsen R, Yang H, Wang J, Wang X, Wang J.
Nature Biotechnology 2011, 29:1019–1023