Arne Sahm

Germany
Phone: +49 3641 656050
Email: arne.sahm@leibniz-fli.de

Molecular pattern associazed with exeptional lomg healthspan - the mole rats (Bathyergidae)

Leibniz Institute on Aging - Fritz Lipmann Institute (FLI): Platzer Research Group

First Supervisor:

Matthias Platzer (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)), Karol Szafranski (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI))

Publications 2017:

  • Parallel evolution of genes controlling mitonuclear balance in short-lived annual fishes.
    Sahm A, Bens M, Platzer M, Cellerino A
    Aging Cell 2017, 16(3), 488-96
  • PosiGene: automated and easy-to-use pipeline for genome-wide detection of positively selected genes.
    Sahm A, Bens M, Platzer M, Szafranski K
    Nucleic Acids Res 2017 (epub ahead of print)

Publications 2016:

  • FRAMA: from RNA-seq data to annotated mRNA assemblies.
    Bens M, Sahm A, Groth M, Jahn N, Morhart M, Holtze S, Hildebrandt TB, Platzer M, Szafranski K
    BMC Genomics 2016, 17(1), 54
  • Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat.
    Dziegelewska M, Holtze S, Vole C, Wachter U, Menzel U, Morhart M, Groth M, Szafranski K, Sahm A, Sponholz C, Dammann P, Huse K, Hildebrandt** T, Platzer** M
    Redox Biol 2016, 8, 192-8 ** co-senior authors
  • Outgroups and Positive Selection: The Nothobranchius furzeri Case.
    Sahm A, Platzer M, Cellerino A
    Trends Genet 2016, 32(9), 523-5

Publications 2015:

  • Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish.
    Reichwald* K, Petzold* A, Koch* P, Downie* BR, Hartmann* N, Pietsch S, Baumgart M, Chalopin D, Felder M, Bens M, Sahm A, Szafranski K, Taudien S, Groth M, Arisi I, Weise A, Bhatt SS, Sharma V, Kraus JM, Schmid F, Priebe S, Liehr T, Görlach M, Than ME, Hiller M, Kestler HA, Volff JN, Schartl M, Cellerino** A, Englert** C, Platzer** M
    Cell 2015, 163(6), 1527-38 * equal contribution, ** co-senior authors, featured in Cell Preview by Vanisha Lakhina and Coleen T. Murphy: Genome Sequencing Fishes out Longevity Genes. Cell. 2015 163(6):1312-3,Nature News by Ewen Callaway: Short-lived fish may hold clues to human age

Publications 2014:

  • Unusual Ratio between Free Thyroxine and Free Triiodothyronine in a Long-Lived Mole-Rat Species with Bimodal Ageing.
    Henning Y, Vole C, Begall S, Bens M, Broecker-Preuss M, Sahm A, Szafranski K, Burda H, Dammann P
    PLoS One 2014, 9(11), e113698